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1国际宫颈腺癌标准和分类:宫颈浸润性腺癌一种新的病理分类显示文摘与2014版WHO分类不同,作者试图根据与病因[即人类乳头瘤病毒(HPV)感染]相关的形态学特征对宫颈腺癌(ECAs)进行分类。该文描述的国际宫颈腺癌标准和分类(IECC标准)将ECAs区分为两种类型,即人乳头状瘤病毒相关性腺癌(HPVA)(高倍可见腺上皮的核分裂和细胞凋亡)和无或有限的HPVA特征的宫颈腺癌[非人类乳头状瘤病毒相关性腺癌(HPVA)],然后根据胞质特点对HPVA进行分类(主要是提供与现有分类方案的连续性)。解建军 张仁亚 Stolnicu S Barsan I Hoang L 2018临床与实验病理学杂志2018,34,11:74
2Environmental issues from coal mining and their solutions显示文摘The environmental challenges from coal mining include coal mine accidents,land subsidence,damage to the water environment,mining waste disposal and air pollution.These are either environmental pollution or landscape change.A conceptual framework for solving mine environmental issues is proposed.Clean processes,or remediation measures,are designed to address environmental pollution.Restoration measures are proposed to handle landscape change.The total methane drainage from 56 Chinese high methane concentration coal mines is about 101.94 million cubic meters.Of this methane,19.32 million,35.58 million and 6.97 million cubic meters are utilized for electricity generation,civil fuel supplies and other industrial purposes,respectively.About 39% of the methane is emitted into the atmosphere.The production of coal mining wastes can be decreased 10% by reuse of mining wastes as underground fills,or by using the waste as fuel for power plants or for raw material to make bricks or other infrastructure materials.The proper use of mined land must be decided in terms of local physical and socio-economical conditions.In European countries more than 50% of previously mined lands are reclaimed as forest or grass lands.However,in China more than 70% of the mined lands are reclaimed for agricultural purposes because the large population and a shortage of farmlands make this necessary.Reconstruction of rural communities or native residential improvement is one environmental problem arising from mining.We suggest two ways to reconstruct a farmer's house in China.BIAN, Zhengfu INYANG, Hilary I DANIELS, John L OTTO, Frank STRUTHERS, Sue 2010Mining Science and Technology2010,20,2:47
3The Chromosome-Level Reference Genome of Tea Tree Unveils Recent Bursts of Nonautonomous LTR Retrotransposons in Driving Genome Size Evolution显示文摘Dear Editor,The tea tree Camellia sinensis,a member of the genus Camellia in the Theaceae family,includes two major cultivated varieties,C.sinensis var.assamica(CSA\Assam type)and C.sinensis var.sinensis(CSS;Chinese type)(Ming and Bartholomew,2007).Due to the high economic importance of the tea tree,considerable efforts have been made to explore genetic basis of the biosynthesis of natural metabolites that determine health benefits and diverse tea flavors(Shi et al.,2011;Li et al.,2011;Li et al.,2015;Xia et aL,2017;Liu et al.,2019).Qun-Jie Zhang Wei L i Kui Li Hong Nan Cong Shi Yun Zhang Zhang-Yan Dai Yang-Lei Lin Xiao-Lan Yang Yan Tong Dan Zhang Cui Lu Li-Ying Feng Chen-Feng Wang Xiao-Xin Liu Jian-An Huang Wen-Kai Jiang Xing-Hua Wang Xing-Cai Zhang Evan E.Eichler Zhong-Hua Liu and Li-Zhi Gao 2020Molecular Plant2020,13,7:27
4OPTICAL PROPERTIES OF GeO_2 AND Ge NANOCRYSTALS显示文摘he co m pound m aterial of n m size particles Ge O2 Si O2 w as synthesied through hydrolysis of Si( O C2 H4) and Ge Cl4 . A heat treatm ent w as carried out for the sa m ples at 100 ~1200 ℃in air . Its optical property w as deter mined by U V Vis spectur m . We have found that theabsorption edge of spectru m shifted progressively to longer w avelengths . The quantu m size ef fect of nanocrystals appears because crystals gro w and energy of optical band gap reduces d ueto the influence of te m perature . By the analysis of X ray diffraction w e have observed theprocess in w hich the structure of particles changed fro m disorder into order .Y.H.Zhou 1) ,Y.Y.Feng 2) and H.Y.Lu 2) 1)Department of Physics Nanjing Normal University, Nanjing 210097,China 2)Physics and Ch寁O P T I C A L P R O P E R T I E S O F Ge O2 A N D Ge N A N O C R Y S T A L S Y. H. Zhou1) , Y. Y. Feng2) 1999Acta Metallurgica Sinica(English Letters)1999,12,5:22
5微小RNA-1和微小RNA-29b对急性心肌梗死后不良心室重塑的诊断和预后价值显示文摘已知微小RNA(microRNAs,miRs)在急性心肌梗死(acute myocardial infarction,AMI)临床前期模型中可发挥纤维化和抗纤维化作用。为了评估miR-1,miR-21,miR-29b和miR-92a能否作为患者发生AMI后不良心室重塑(adverse ventricular remodeling,AVR)的循环生物标志物,刘莉 叶鹏 Grabmaier U Clauss S Gross L Klier I Franz WM Steinbeck G Wakili R Theiss HD Brenner C 2017中华高血压杂志2017,25,7:17
6具有极性反转的乳头状肾肿瘤:形态学、免疫组化和分子学研究显示文摘作者评估了特殊类型乳头状肾肿瘤的临床病理和染色体特征,并将其与1型和2型乳头状肾细胞癌进行比较。18例中,9例男性,9例女性;年龄范围46~80岁(平均64岁,中位年龄66岁);肿瘤直径0.6~3 cm(平均1.63 cm,中位直径1.4 cm);其中14例WHO/ISUP 2级,4例WHO/ISUP 1级,肿瘤分期均为pT1期。这类肿瘤具有细小纤维血管轴心的分支状乳头,被覆立方/柱状细胞,胞质颗粒状嗜酸性,管腔边缘光滑,核规则且多位于细胞顶端,偶尔核仁明显或不明显。5例形成小管状结构,9例有明显的胞质空泡,10例具有假包膜。18例肿瘤均无砂粒体、坏死、核分裂象和细胞内含铁血黄素沉积。相比之下,1型乳头状肾细胞癌具有纤细的乳头状结构,被覆单层细胞,胞质稀少,细胞核通常位于乳头状结构基底部呈单层排列,而2型乳头状肾细胞癌具有较宽的乳头状结构,表面被覆细胞呈假复层排列,胞质嗜酸性,核无规则分布。1型和2型乳头状肾细胞癌可见砂粒体、泡沫样巨噬细胞以及细胞内含铁血黄素沉积。免疫组化结果显示,18例肿瘤中CK(AE1/AE3)、EMA、MUC1、CD10、GATA3和L1CAM均阳性。魏建国(摘译) 方三高(审校) Al-Obaidy K I Eble J N Cheng L 2019临床与实验病理学杂志2019,35,8:15
7Recovery of valuable metals from a low-grade nickel ore using an ammonium sulfate roasting-leaching process显示文摘Metal leaching from a low-grade nickel ore was investigated using an ammonium sulfate roasting-water leaching process.The nickel ore was mixed with ammonium sulfate,followed by roasting and finally leaching with water.During the process the effects of the amount of ammonium sulfate,roasting temperature,and roasting time on the leaching recovery of metal elements were analyzed.The optimum technological parameters were determined as follows:ammonium sulfate/ore ratio,0.8 g/g;roasting temperature,400°C;and roasting time,2 h.Under the optimum condition the leaching recoveries of Ni,Cu,Fe,and Mg were 83.48%,76.24%,56.43%,and 62.15%,respectively.Furthermore,the dissolution kinetics of Ni and Mg from the nickel ore was studied.The apparent activation energies for the leaching reaction of Ni and Mg were 18.782 and 10.038 kJ·mol-1,which were consistent with the values of diffusion control reactions.Therefore,the results demonstrated that the leaching recoveries of Ni and Mg were controlled by diffusion.Xin-wei L iu Ya-li Feng Hao-ran L i Zhi-chao Yang Zhen-lei Cai 2012International Journal of Minerals,Metallurgy and Materials2012,19,5:14
8Helicobacter pylori and autoimmune disease:Cause or bystander显示文摘Helicobacter pylori(H.pylori)is the main cause of chronic gastritis and a major risk factor for gastric cancer.This pathogen has also been considered a potential trigger of gastric autoimmunity,and in particular of autoimmune gastritis.However,a considerable number of reports have attempted to link H.pylori infection with the development of extra-gastrointestinal autoimmune disorders,affecting organs not immediately relevant to the stomach.This review discusses the current evidence in support or against the role of H.pylori as a potential trigger of autoimmune rheumatic and skin diseases,as well as organ specific autoimmune diseases.We discuss epidemiological,serological,immunological and experimental evidence associating this pathogen with autoimmune diseases.Although over one hundred autoimmune diseases have been investigated in relation to H.pylori,we discuss a select number of papers with a larger literature base,and include Sj grens syndrome,rheumatoid arthritis,systemic lupus erythematosus,vasculitides,autoimmune skin conditions,idiopathic thrombocytopenic purpura,autoimmune thyroid disease,multiple sclerosis,neuromyelitis optica and autoimmune liver diseases.Specific mention is given to those studies reporting an association of anti-H.pylori antibodies with the presence of autoimmune disease-specific clinical parameters,as well as those failing to find such associations.We also provide helpful hints for future research.Daniel S Smyk Andreas L Koutsoumpas Maria G Myt-ilinaiou Eirini I Rigopoulou Lazaros I Sakkas Dimitrios P Bogdanos 2014World Journal of Gastroenterology2014,20,3:12
9玉米种子大小和播深对出苗和幼苗活力的影响显示文摘林波波河省小农户主要以玉米为主粮来生产,播种时常因翻耕翻埋种子而造成植株个体生长差。本研究目的就是要确定种子大小和播种深度对玉米出苗和生长的影响。实验处理包括两种不同大小的种子(大粒种子和小粒种子)和4个播种深度(5cm、10cm、15cm、20cm)。种子大小对出苗率无显著影响,但不同播深对出苗率有显著影响。种子大小和播种深度均对幼苗高度有显著影响。种子大小对幼苗干重和叶片数没有影响。随播种深度增加,幼苗干重减少。结果显示,播深在5cm和10cm时,种子大小对出苗和幼苗活力没有影响,但播种深度在15cm和20cm时,对出苗和种子活力有不良影响。Molatudi R L Mariga I K 马志强 2010中国种业2010,,7:11
10Relationship between the exocrine and endocrine pancreas after acute pancreatitis显示文摘AIM:To determine the prevalence and time course of pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.METHODS:Relevant literature cited in three major biomedical journal databases(EMBASE,MEDLINE,and Scopus)was reviewed independently by two authors.There were no language constraints but the search was limited to human studies.Studies included were cohort studies of adult patients who were discharged after an attack of acute pancreatitis.Patients were excluded if they were under 18 years of age or had a previous diagnosis of prediabetes or diabetes mellitus,pancreatic exocrine insufficiency,or chronic pancreatitis.The main outcome measure was the prevalence of concomitant pancreatic exocrine insufficiency in patients who were diagnosed with prediabetes and diabetes mellitus after an attack of acute pancreatitis.Subgroup analysis was conducted for patients who were diagnosed with prediabetes only and those who were diagnosed withdiabetes mellitus only.Subgroup analysis looking at the time course of concomitant pancreatic exocrine and endocrine insufficiency was also conducted.Pooled prevalence and corresponding 95%confidence intervals were calculated for all outcome measures and P-values<0.05 were deemed statistically significant.RESULTS:Eight clinical studies comprising of 234patients met all eligibility criteria.The pooled prevalence of newly diagnosed prediabetes or diabetes in individuals after acute pancreatitis was 43%(95%CI:30%-56%).The pooled prevalence of pancreatic exocrine insufficiency in individuals after acute pancreatitis was 29%(95%CI:19%-39%).The prevalence of concomitant pancreatic exocrine insufficiency in individuals with newly diagnosed prediabetes or diabetes was 40%(95%CI:25%-55%).The prevalence of concomitant pancreatic exocrine insufficiency among individuals with prediabetes alone and diabetes mellitus alone was 41%(95%CI:12%-75%)and 39%(95%CI:28%-51%),respectively.Further analysis showed that the prevalence of concomitant pancreatic exocrine insufficiency in individuals with prediabetes or diabetes decreases over time after an attack of acute pancreatitis.CONCLUSION:Pancreatic exocrine insufficiency occurs in 40%of individuals with newly diagnosed prediabetes or diabetes mellitus after acute pancreatitis.Further studies are needed to investigate the pathogenesis of diabetes in this setting.Stephanie L M Das James I C Kennedy Rinki Murphy Anthony R J Phillips John A Windsor Maxim S Petrov 2014World Journal of Gastroenterology2014,20,45:9
11Dietary and metabolomic determinants of relapse in ulcerative colitis patients: A pilot prospective cohort study显示文摘AIM To identify demographic, clinical, metabolomic, and lifestyle related predictors of relapse in adult ulcerative colitis(UC) patients.METHODS In this prospective pilot study, UC patients in clinical remission were recruited and followed-up at 12 mo to assess a clinical relapse, or not. At baseline information on demographic and clinical parameters was collected. Serum and urine samples were collected for analysis of metabolomic assays using a combined direct infusion/liquid chromatography tandem mass spectrometry and nuclear magnetic resolution spectroscopy. Stool samples were also collected to measure fecal calprotectin(FCP). Dietary assessment was performed using a validated self-administered food frequency questionnaire. RESULTS Twenty patients were included(mean age: 42.7 ± 14.8 years, females: 55%). Seven patients(35%) experienced a clinical relapse during the follow-up period. While 6 patients(66.7%) with normal body weight developed a clinical relapse, 1 UC patient(9.1%) who was overweight/obese relapsed during the follow-up(P = 0.02). At baseline, poultry intake was significantly higher in patients who were still in remission during follow-up(0.9 oz vs 0.2 oz, P = 0.002). Five patients(71.4%) with FCP > 150 μg/g and 2 patients(15.4%) with normal FCP(≤ 150 μg/g) at baseline relapsed during the follow-up(P = 0.02). Interestingly, baseline urinary and serum metabolomic profiling of UC patients with or without clinical relapse within 12 mo showed a significant difference. The most important metabolites that were responsible for this discrimination were trans-aconitate, cystine and acetamide in urine, and 3-hydroxybutyrate, acetoacetate and acetone in serum. CONCLUSION A combination of baseline dietary intake, fecal calprotectin, and metabolomic factors are associated with risk of UC clinical relapse within 12 mo.Ammar Hassanzadeh Keshtel iFloris F van den Brand Karen L Madsen Rupasri Mandal Rosica ValchevaKaren I Kroeker Beomsoo Han Rhonda C Bell Janis Cole Thomas Hoevers David S Wishart Richard N Fedorak Levinus A Dieleman 2017World Journal of Gastroenterology2017,23,21:9
12Titanium dioxide induced inflammation in the small intestine显示文摘AIM:To investigate the effects of titanium dioxide (TiO2) nanoparticles (NPTiO 2 ) and microparticles (MPTiO 2 ) on the inflammatory response in the small intestine of mice. METHODS: Bl 57/6 male mice received distilled water suspensions containing TiO 2 (100 mg/kg body weight) as NPTiO 2 (66 nm), or MPTiO 2 (260 nm) by gavage for 10 d, once a day; the control group received only distilled water. At the end of the treatment the duodenum, jejunum and ileum were extracted for assessment of cytokines, inflammatory cells and titanium content. The cytokines interleukin (IL)-1b, IL-4, IL-6, IL-8, IL-10, IL-12, IL-13, IL-17, IL-23, tumor necrosis factor-α (TNF-α), intracellular interferon-γ (IFN-γ) and transforming growth factor-β (TGF-β) were evaluated by enzyme-linked immunosorbent assay in segments of jejunum and ileum (mucosa and underlying muscular tissue). CD4 + and CD8 + T cells, natural killer cells, and dendritic cells were evaluated in duodenum, jejunum and ileum samples fixed in 10% formalin by immuno-histochemistry. The titanium content was determined by inductively coupled plasma atomic emission spectrometry. RESULTS: We found increased levels of T CD4 + cells (cells/mm 2 ) in duodenum:NP 1240 ± 139.4, MP 1070 ± 154.7 vs 458 ± 50.39 (P < 0.01); jejunum:NP 908.4 ± 130.3, MP 813.8 ± 103.8 vs 526.6 ± 61.43 (P < 0.05); and ileum:NP 818.60 ± 123.0, MP 640.1 ± 32.75 vs 466.9 ± 22.4 (P < 0.05). In comparison to the control group, the groups receiving TiO 2 showed a statistically significant increase in the levels of the inflammatory cytokines IL-12, IL-4, IL-23, TNF-α, IFN-γ and TGF-β. The cytokine production was more pronounced in the ileum (mean ± SE):IL-12: NP 33.98 ± 11.76, MP 74.11 ± 25.65 vs 19.06 ± 3.92 (P < 0.05); IL-4: NP 17.36 ± 9.96, MP 22.94 ± 7.47 vs 2.19 ± 0.65 (P < 0.05); IL-23: NP 157.20 ± 75.80, MP 134.50 ± 38.31 vs 22.34 ± 5.81 (P < 0.05); TNFα: NP 3.71 ± 1.33, MP 5.44 ± 1.67 vs 0.99± 019 (P < 0.05); IFNγ: NP 15.85 ± 9.99, MP 34.08 ± 11.44 vs 2.81 ± 0.69 (P < 0.05); and TGF-β: NP 780.70 ± 318.50, MP 1409.00 ± 502.20 vs 205.50 ± 63.93 (P < 0.05). CONCLUSION:Our findings indicate that TiO2 particles induce a Th1-mediated inflammatory response in the small bowel in mice.Carolina Maciel Nogueira Walter Mendes de Azevedo Maria Lucia Zaidan Dagli Sérgio Hiroshi Toma AndréZonetti de Arruda Leite Maria Laura Lordello Iêda Nishitokukado Carmen Lúcia Ortiz-Agostinho Maria IrmaSeixas Duarte Marcelo Alves Ferreira Aytan Miranda Sipahi 2012World Journal of Gastroenterology2012,18,34:8
13A Multiscalar Drought Index Sensitive to Global Warming: The Standardized Precipitation Evapotranspiration Index显示文摘Vicente-Serrano Sergio M Beguería Santiago López-Moreno Juan I 2010Journal of Climate2010,,7:8
14半嵌套式PCR检测转几丁质酶基因烟草研究显示文摘用含卡那霉素的培养基首先对转几丁质酶基因烟草种子和烟苗进行初步筛选鉴定 ,再用 Western Blot进一步证实抗卡那霉素的转基因烟苗中外源转几丁质酶基因的表达。然后研究半嵌套式 PCR(Semi- nested PCR)检测转几丁质酶基因烟草植株及其烤后烟叶中的所转目的基因 ;利用限制性内切酶 H ind 对半嵌套式 PCR产物进行酶切 ,从而验证半嵌套式 PCR产物是否为真正的目的基因。研究结果表明 ,半嵌套式 PCR是一种快速。时焦 M Naylor M L Edwards J I Cooper 韩锦峰 2002中国烟草学报2002,8,2:8
15Metadoxine improves the three- and six-month survival rates in patients with severe alcoholic hepatitis显示文摘AIM:To evaluate the impact of metadoxine(MTD) on the 3- and 6-mo survival of patients with severe alcoholic hepatitis(AH).METHODS:This study was an open-label clinical trial,performed at the'Hospital General de México,Dr.Eduardo Liceaga'.We randomized 135 patients who met the criteria for severe AH into the following groups:35 patients received prednisone(PDN)40 mg/d,35patients received PDN+MTD 500 mg three times daily,33 patients received pentoxifylline(PTX)400 mg three times daily,and 32 patients received PTX+MTD 500 mg three times daily.The duration of the treatment for all of the groups was 30 d.RESULTS:In the groups treated with the MTD,thesurvival rate was higher at 3 mo(PTX+MTD 59.4%vs PTX 33.3%,P=0.04;PDN+MTD 68.6%vs PDN20%,P=0.0001)and at 6 mo(PTX+MTD 50%vs PTX18.2%,P=0.01;PDN+MTD 48.6%vs PDN 20%,P=0.003)than in the groups not treated with MTD.A relapse in alcohol intake was the primary independent factor predicting mortality at 6 mo.The patients receiving MTD maintained greater abstinence than those who did not receive it(74.5%vs 59.4%,P=0.02).CONCLUSION:MTD improves the 3-and 6-mo survival rates in patients with severe AH.Alcohol abstinence is a key factor for survival in these patients.The patients who received the combination therapy with MTD were more likely to maintain abstinence than those who received monotherapy with either PDN or PTX.Fátima Higuera-de la Tijera Alfredo I Servín-Caamano Aurora E Serralde-Zúniga Javier Cruz-Herrera Eduardo Pérez-Torres Juan M Abdo-Francis Francisco Salas-Gordillo JoséL Pérez-Hernández 2015World Journal of Gastroenterology2015,21,16:8
16Breath test for differential diagnosis between small intestinal bacterial overgrowth and irritable bowel disease:An observation on non-absorbable antibiotics显示文摘AIM: To estimate the prevalence of small intestine bacterial overgrowth (SIBO) among patients with an earlier diagnosis of irritable bowel disease (IBS) in our geographical area, and to collect information on the use of locally acting non-absorbable antibiotics in the management of SIBO. METHODS: A non-interventional study was conducted in 73 consecutive patients with a symptom-based diagnosis.. RESULTS: When the patients underwent a 'breath test', 33 (45.2%) showed the presence of a SIBO. After treatment with rifaximin 1200 mg/d for seven days in 32 patients, 19 (59.4%) showed a negative 'breath test' one week later as well as a significant reduction of symptoms, thus confirming the relationship between SIBO and many of the symptoms claimed by patients. In the other 13 patients, 'breath test' remained positive, and a further cycle of treatment with ciprofloxacin 500 mg/d was given for 7 additional days, resulting in a negative 'breath test' in one patient only. CONCLUSION: (1) about half of the patients with a symptomatic diagnosis of IBS have actually SIBO, which is responsible for most of the symptoms attributed to IBS; (2) only a 'breath test' with lactulose (or with glucose in subjects with an intolerance to lactose) can provide a differential diagnosis between IBS and SIBO, with almost identical symptoms; and (3) the use of non-absorbable antibiotics may be useful to reduce the degree of SIBO and related symptoms; it must be accompanied, however, by the correction of the wrong alimentary habits underlying SIBO.I Esposito A de Leone G Di Gregorio S Giaquinto L de Magistris A Ferrieri G Riegler 2007World Journal of Gastroenterology2007,13,45:8
17Review of the treatment of liver hydatid cysts显示文摘A review was carried out in Medline,LILACS and the Cochrane Library.Our database search strategy included the following terms: 'hydatid cyst','liver','management','meta-analysis' and 'randomized controlled trial'.No language limits were used in the literature search.The latest electronic search date was the 7th of January 2014.Inclusion and exclusion criteria: all relevant studies on the assessment of therapeutic methods for hydatid cysts of the liver were considered for analysis.Information from editorials,letters to publishers,low quality review articles and studies done on animals were excluded from analysis.Additionally,well-structured abstracts from relevant articles were selected and accepted for analysis.Standardized forms were designed for data extraction; two investigators entered the data on patient demographics,methodology,recurrence of HC,mean cyst size and number of cysts per group.Four hundred and fourteen articles were identified using the previously described search strategy.After applying the inclusion and exclusion criteria detailed above,57 articles were selected for final analysis: one meta-analysis,9 randomized clinical trials,5 non-randomized comparative prospective studies,7 non-comparative prospective studies,and 34 retrospective studies(12 comparative and 22 noncomparative).Our results indicate that antihelminthic treatment alone is not the ideal treatment for liver hydatid cysts.More studies in the literature support the effectiveness of radical treatment compared with conservative treatment.Conservative surgery with omentoplasty is effective in preventing postoperative complications.A laparoscopic approach is safe in some situations.Percutaneous drainage with albendazole therapy is a safe and effective alternative treatment for hydatid cysts of the liver.Radical surgery with preand post-operative administration of albendazole is the best treatment option for liver hydatid cysts due to low recurrence and complication rates.Concepción Gomez i Gavara Rafael López-Andújar Tatiana Belda Ibáez José M Ramia ngel ngel Moya Herraiz Francisco Orbis Castellanos Eugenia Pareja Ibars Fernando San Juan Rodríguez 2015World Journal of Gastroenterology2015,21,1:8
18Ultrafine Grained HSLA Steels for Cold Forming显示文摘The industrial level production of ultrafine grained(or ultrafine ferrite)ferrous alloys was investigated through three examples of steels that complied with the EN 10149-2 Euronorm and were produced by advanced controlled hot rolling techniques.The steel samples were tension tested and chemically analyzed,and the microstructure was evaluated through quantitative metallographic techniques to determine parameters such as yield stress,amount of microalloying elements,strain hardening coefficient,grain size,and grain size distribution.These steels were microalloyed with Ti,Nb,and Mn with ASTM grain sizes of approximately 13-15.The careful control of chemical composition and deformation during production,giving a specific attention to the deformation sequences,austenite non-recrystallization temperatures and allotropic transformations during cooling,are indispensable to obtain steels with an adequate strain hardening coefficient that allows cold working operations such as bending,stretching or drawing.R González J O García M A Barbés M J Quintana L F Verdeja J I Verdeja 2010Journal of Iron and Steel Research(International)2010,17,10:7
19Recurrence of inflammatory pseudotumor in the distal bile duct: Lessons learned from a single case and reported cases显示文摘煽动性的 myofibroblastic 肿瘤(IMT ) 或煽动性的假肿瘤(IP ) 广泛地在文学被讨论了。他们通常在肺和上面的呼吸道被发现。然而,包含 biliopancreatic 区域的案例报导在最近的年增加了。限制到胰腺的头或远侧的胆汁管的这些损害的 Immunohistochemical 学习似乎与那些在称为自体免疫的胰腺炎的一个新实体观察了兼容,但是通常强烈的纤维变性反应(带状配列) 支配生产一个团。当这个条件限于胰腺的头时,胆总管可能被煽动性的过程包含,黄疸可以经常发生类似于胰的腺癌。我们以前报导了从与是一个极其稀罕的实体的自体免疫的胰腺炎联系的胆汁管产生的 IMT 的一个案例。在 Kaush-Whipple 切除术以后的四年,平淡的后续上的放射学的检查揭示了一个肿瘤团,建议本地复发。指导超声的 FNA 证实了我们的可疑诊断。作为其它,这个现在的案例建议坚持的后续是必要的以便在这个特定的地点阻止不可逆的肝损坏。EM López-Tomassetti Fernández H Díaz Luis A Martín Malagón I Arteaga González A Carrillo Pallarés 2006World Journal of Gastroenterology2006,12,24:7
20Thermal Ablation in the Management of Adrenal Metastasis Originating from Non-small Cell Lung Cancer: A 5-year Single-center Experience显示文摘Evanthia I Botsa Ioanna L Thanou Aspasia T Papatheodoropoulou Loukas I Thanos 2017Chinese Medical Journal2017,,17:6
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