维普中文期刊产品整合服务
7篇 您的检索式:作者名="Kyria"
    题名 作者 年代 出处 被引量
1Antioxidant role of zinc in diabetes mellitus显示文摘Chronic hyperglycemia statue noticed in diabetes mellitus favors the manifestation of oxidative stress by increasing the production of reactive oxygen species and/or by reducing the antioxidant defense system activity.Zinc plays an important role in antioxidant defense in type2 diabetic patients by notably acting as a cofactor of the superoxide dismutase enzyme,by modulating the glutathione metabolism and metallothionein expression,by competing with iron and copper in the cell membrane and by inhibiting nicotinamide adenine dinucleotide phosphate-oxidase enzyme.Zinc also improves the oxidative stress in these patients by reducing chronic hyperglycemia.It indeed promotes phosphorylation of insulin receptors by enhancing transport of glucose into cells.However,several studies reveal changes in zinc metabolism in individuals with type 2 diabetes mellitus and controversies remain regarding the effect of zinc supplementation in the improvement of oxidative stress in these patients.Faced with the serious challenge of the metabolic disorders related to oxidative stress in diabetes along with the importance of antioxidant nutrients in the control of this disease,new studies may contribute to improve our understanding of the role played by zinc against oxidative stress and its connection with type 2 diabetes mellitus prognosis.This could serve as a prelude to the development of prevention strategies and treatment of disorders associated with this chronic disease.Kyria Jayanne Clímaco Cruz Ana Raquel Soares de Oliveira Dilina do Nascimento Marreiro 2015World Journal of Diabetes2015,6,2:4
2Subcutaneous Administration of Amifostine during Fractionated Radiotherapy:A Randomized Phase Ⅱ Study显示文摘Koukourakis M I Kyrias G Kakolyris S 2000J Clin Oncol2000,18,11:1
3Dexmeditomi- dine as an anaesthetic adjuvant in patients undergoing intracra- nial tumour surgery:a double-blind, randomized and placebo- controlled study显示文摘TANSKANEN P E KyrIA J V RANDELL T T 2006Br J Anaesth2006,,97:1
4Bilateral seconda- ry neurolymphomatosis of the internal auditory canal nerves a case report显示文摘Blioskas S Tsaligopoulos M Kyria Cinis G 2013Am J Otolaryngol2013,34,55:1
5Mammalian mitogen-activated protein kinase signal transduction pathway activated by stress and inflammation显示文摘Kyria JM Avrueh J 2001Physiol Rev2001,81,2:1
6Subcutaneous adminis- tration of amifostine during fractionated radiotherapy : arandomized phase ]I study 显示文摘Koukourakis MI Kyrias G Kakolyris S 2000J Clin Oncol2000,18,11:1
7Subcutaneous administration of amifostine during fractionated radiotherapy:a randomized phase Ⅱ study显示文摘Koukourakis MI Kyrias G Kakolyris S 2000J Clin Oncol2000,18,:1
返回顶部 每页显示:
共1页 首页 上一页 第1页 下一页 末页 /1 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费