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| 1 | 不同入路冠状动脉介入治疗术围手术期周围血管并发症发生率的对比显示文摘目的:比较经股动脉和桡动脉入路冠状动脉介入治疗(percutaneous coronary intervention,PCI)术中周围血管并发症的发生率,为其临床诊治提供参考。方法:分析2014年7月至2016年12月在我院心血管介入治疗中心进行冠状动脉造影及介入治疗的780例患者的临床资料,比较周围血管并发症发生情况。结果:经股动脉途径471例,经桡动脉途径309例。经股动脉途径总体并发症发生率13.2%,高于经桡动脉途径的4.5%,差异有统计学意义(P<0.001)。经股动脉途径出血并发症发生率为7.9%,高于经桡动脉途径2.6%,差异有统计学意义(P=0.002)。经股动脉途径患者重大并发症(后腹膜血肿、假性动脉瘤、动静脉瘘、动脉夹层形成)发生率高于经桡动脉途径(2.1%vs 0%),但差异无统计学意义。结论:经股动脉途径冠状动脉介入治疗术围手术期周围血管并发症发生率高于经桡动脉途径,临床入路选择时需综合考虑。 | 张树清 崔磊 祁荣兴 SANJEEV KUMAR P S 黄胜 葛莉 钱澄 | 2017 | 中国临床医学2017，24，5： | 11 |
| 2 | Antimicrobial potential of Actinomycetes species isolated from marine environment显示文摘Objective:To evaluate the antimicrobial activity of Actinomycetes species isolated from marine environment.Methods:Twenty one strains of Actinomyceteswere isolated from samples of Royapuram, Muttukadu, Mahabalipuram sea shores and Adyar estuary. Preliminary screening was done using cross-streak method against two gram-positive and eight gram-negative bacteria.The most potent strains C11 and C12 were selected from which antibacterial substances were extracted. The antibacterial activities of the extracts were performed using Kirby-Bauer disc diffusion method. Molecular identification of those isolates was done.Results:All those twenty one isolates were active against at least one of the test organisms. Morphological characters were recorded. C11 showed activity againstStaphylococcusspecies(13.0暲0.5 mm),Vibrio harveyi(11.0暲0.2 mm),Pseudomonas species(12.0暲0.3 mm). C12 showed activity against Staphylococcus species(16.0暲0.4 mm),Bacillus subtilis(11.0暲0.2 mm),Vibrio harveyi(9.0暲0.1 mm),Pseudomonas species(10.0暲0.2 mm). 16S rRNA pattern strongly suggested that C11 and C12 strains were Streptomyces species.Conclusions:The results of the present investigation reveal that the marineActinomycetesfrom coastal environment are the potent source of novel antibiotics.Isolation, characterization and study of Actinom ycetescan be useful in discovery of novel species of Actinomy cetes. | Valli S Suvathi Sugasini S Aysha OS Nirmala P Vinoth Kumar P Reena A | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 8 |
| 3 | Laparoscopic liver resection:Wedge resections to living donor hepatectomy, are we heading in the right direction?显示文摘Despite inception over 15 years ago and over 3000 completed procedures, laparoscopic liver resection has remained mainly in the domain of selected centers and enthusiasts. Requirement of extensive open liver resection(OLR) experience, in-depth understanding of anatomy and considerable laparoscopic technical expertise may have delayed wide application. However healthy scepticism of its actual benefits and presence of a potential publication bias; concern about its safety and technical learning curve, are probably equally responsible. Given that a large proportion of our work, at least in transplantation is still OLR, we have attempted to provide an entirely unbiased, mature opinion of its pros and cons in the current invited review. We have dividedthis review into two sections as we believe they merit separate attention on technical and ethical grounds. The first part deals with laparoscopic liver resection(LLR) in patients who present with benign or malignant liver pathology, wherein we have discussed its overall outcomes; its feasibility based on type of pathology and type of resection and included a small section on application of LLR in special scenarios like cirrhosis. The second part deals with the laparoscopic living donor hepatectomy(LDH) experience to date, including its potential impact on transplantation in general. Donor safety, graft outcomes after LDH and criterion to select ideal donors for LLR are discussed. Within each section we have provided practical points to improve safety in LLR and attempted to reach reasonable recommendations on the utilization of LLR for units that wish to develop such a service. | P Thomas Cherian Ashish Kumar Mishra Palaniappen Kumar Vijayant Kumar Sachan Anand Bharathan Gadiyaram Srikanth Baiju Senadhipan Mohamad S Rela | 2014 | World Journal of Gastroenterology2014，20，37： | 4 |
| 4 | Synthesis and evaluation of novel analogues of mangiferin as potent antipyretic显示文摘Objective:To screen different analogues of mangiferin pharmacologically for antipyretic activity. Methods:The naturally occurring xanthone glycoside mangiferin was isolated by column chromatography from the elhanolic extract of stem bark of Mangifera indica.Mangiferin was further converted to 5-(N-phenylamino methyleno) mangiferin.5-(N-p-chlorophenylamino methyleno) mangiferin,5-(N-2-methyl phenylamino methyleno) mangiferin.5-(N-p-methoxy phenylamino methyleno) mangiferin.5-(N,N-diphenylamino methyleno) mangiferin,5-(N-α-napthylamino methyleno) mangiferin and 5-(N-4-methyl phenylamino methyleno) mangiferin analogues.The synthesized compounds were further screened for antipyretic activity along with mangiferin at a dose level of 100 and 200 tng/kg.Mangiferin and its analogues were characterized by melting point and R_f value determination and through spectral technique like UV,IR,and NMR spectral analysis.Results:The antipyretic activity of mangiferin as well as all analogues was found to be more significant in at higher dose ie.200 mg/kg which was depicted thmugh a decrease in rectal temperature up to 3 h.Conclusions:The antipyretic activity of mangiferin and its analogues may be attributed to inhibition in synthesis of TNF-αand anti-oxidant activity associated with amelioration of inflammatory actions of cytokines. | Shashi Kant Singh Saurabh K Sinha SK Prasad R Kumar Bhawani S Bithu S Sadish Kumar P Singh | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，11： | 4 |
| 5 | Genetic determinant s of diabetic nephropathy显示文摘 | Chowdhury T A Dyer P H Kumar S | | 0，，： | 2 |
| 6 | Ordered Intermetallics显示文摘 | E P George M Yamaguchi K S Kumar C T Liu | 1994 | Annual Review of Materials Science1994，，： | 2 |
| 7 | A lupane derivative and the 13C-NMR chemical shifts lupanone from Pleurostylia opposita 显示文摘 | Dantanarayana A P Kumar N S | 1982 | Phytochemistry1982，21，8： | 2 |
| 8 | Nanocrystalline TiO2 studied by optical, FTIR and X-ray photoelectron spectroscopy: correlation to presence of surface states 显示文摘 | Madhu Kumar P Badrinarayanan S Sastry M | 2000 | Thin Solid Films2000，358，12： | 2 |
| 9 | Effect of morin, a flavonoid against DOCA-salt hypertensive rats:a dose dependent study显示文摘Objective:To determine the protective effect of morin, a flavonoid against deoxycorticosterone acetate(DOCA)-salt induced hypertension in male Wistar rats.Methods:Hypertension was induced in uninephrectomized rats by weekly twice subcutaneous injection of DOCA(25 mg/kg bw) and 1% NaCl in the drinking water for six consecutive weeks. Effect of morin against DOCA-salt induced hypertension was evaluated by measuring blood pressure and performing biochemical estimations and histopathological examination of renal tissues.Results:DOCA-salt hypertensive rats showed considerably increased systolic and diastolic blood pressure,serum hepatic marker enzyme activities such as aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatase(ALP) and gamma-glutamyl transpeptidase(GGT)and renal function markers(urea, uric acid and creatinine) in plasma. Oral administration of morin(25, 50 and 75 mg/kg bw) brought back all the above parameters to near normal level.Histopathology of kidney also confirmed the biochemical findings of this study. The effect at a dose of 50 mg/kg bw of morin was more pronounced than that of the other two doses(25 and 75 mg/kg bw).Conclusions:These findings indicate that morin exhibits strong antihypertensive effect against DOCA-salt induced hypertension. | Prahalathan P Kumar S Raja B | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，6： | 2 |
| 10 | 改良搅拌摩擦焊修复汽车保险杠显示文摘本文研究了改良搅拌摩擦焊(MFSW)修复热塑性汽车保险杠。聚酰胺(PA6)复合材料常被用于改良搅拌摩擦焊中连接丙烯腈丁二烯苯乙烯(ABS)复合材料。为保证有效范围内的熔体流动特性,对不同的热塑性塑料进行了处理。然后,通过螺杆挤压制备了用于熔融沉积建模(FDM)过程的原料长丝。最后,为改良搅拌摩擦焊制备了基于PA6的3D打印耗材快速模具(RT),并对制备的接头进行了弯曲、硬度、形态和热性能测试。结果表明,在1400 r/min、50 mm/min横向速度和3 mm深度下焊接的样品力学强度最大,在1000 r/min、30 mm/min横向速度和2 mm深度下焊接的样品力学强度最小,该结果与热成像和显微结果一致。 | Ranvijay KUMAR Rupinder SINGH I P S AHUJA | 2020 | Journal of Central South University2020，27，8： | 2 |
| 11 | Non-destructive method of leaf-area determination in ash gourd ( Benincasa hispida) 显示文摘 | Radhakrishnan V V Kumar P G S Oommen A | 1991 | Indian Journal of Agricultural Sciences1991，61，1： | 1 |
| 12 | Isolation of arbuscular mycorrhizal fungi and Azotobacter chroococcum from local litchi orchards and evaluation of their activity in the air-layers system显示文摘 | SHARMA S D KUMAR P RAJ H | 2009 | Scientia Hortieulturae2009，123，： | 1 |
| 13 | Removal of arsenic from water by electrocoagulation显示文摘 | Kumar P R Chaudhari S Khilar K C | 2004 | Chemosphere2004，55，9： | 1 |
| 14 | Effect of the hydrophilic size on the structural phases of aqueous nonionic Gemini surfactant solutions显示文摘 | Nieh M P Kumar S K Fernando R H | 2004 | Langmuir2004，20，21： | 1 |
| 15 | Genetic variants of platelet glycoprotein receptors and risk of stroke in young women 显示文摘 | Reiner A P Kumar P M Schwartz S M | 2000 | Stroke2000，31，7： | 1 |
| 16 | Special issues on sensor networks and applications 显示文摘 | GHARAVI H KUMAR S P | 2003 | Proceedings of the IEEE2003，91，8： | 1 |
| 17 | An approach to the estimation of the value of agricultural residues used as biofuels 显示文摘 | Kumar A Purohit P Rana S | 2002 | Biomass & Bioenergy2002，22，3： | 1 |
| 18 | Zinc biosorption on Tectona grandis L leaves biomass:Equilibrium and kinetic studies显示文摘 | Kumar Y P King P Prasad V S R K | 2006 | Chemical Engineering Journal2006，124，1： | 1 |
| 19 | Combretastatin A-4 analogs as anticancer agents显示文摘 | Chaudhary A Pandeya S N Kumar P | 2007 | Mini Rev Med Chem2007，7，12： | 1 |
| 20 | Benzoxazine-bismaleimide blends; Curing and thermal properties显示文摘 | Santhosh Kumar K S Reghunadhan Nair C P Sadhana R | 2007 | European Polymer Journal2007，43，12： | 1 |
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