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3篇 您的检索式:作者名="Krista Genoway"
    题名 作者 年代 出处 被引量
1Barriers associated with the treatment of hepatitis C virus infection among illicit drug users显示文摘Jason Grebely Krista A. Genoway Jesse D. Raffa Gurbir Dhadwal Tasleem Rajan Grey Showler Kate Kalousek Fiona Duncan Mark W. Tyndall Chris Fraser Brian Conway Benedikt Fischer 2007Drug and Alcohol Dependence2007,,1:1
2Barriers associated with the treatment of hepatitis C virus infection among illicit drug users显示文摘Jason Grebely Krista A. Genoway Jesse D. Raffa Gurbir Dhadwal Tasleem Rajan Grey Showler Kate Kalousek Fiona Duncan Mark W. Tyndall Chris Fraser Brian Conway Benedikt Fischer 2007Drug and Alcohol Dependence2007,,1:1
3Serum estradiol levels decrease after oophorectomy in transmasculine individuals on testosterone therapy显示文摘Transmasculine individuals,considering whether to undergo total hysterectomy with bilateral salpingectomy,have the option to have a concomitant oophorectomy.While studies have evaluated hormone changes following testosterone therapy initiation,most of those patients have not undergone oophorectomy.Data are currently limited to support health outcomes regarding the decision to retain or remove the ovaries.We performed a retrospective chart review of transmasculine patients maintained on high-dose testosterone therapy at a single endocrine clinic in Vancouver,British Columbia,Canada.Twelve transmasculine individuals who underwent bilateral oophorectomy and had presurgical and postsurgical serum data were included.We identified 12 transmasculine subjects as controls,who were on testosterone therapy and did not undergo oophorectomy,but additionally matched to the first group by age,testosterone dosing regimen,and body mass index.There was a statistically significant decrease in the estradiol levels of case subjects postoophorectomy,when compared to presurgical estradiol levels(P=0.02).There was no significant difference between baseline estradiol levels between control and case subjects;however,the difference in estradiol levels at follow-up measurements was significant(P=0.03).Total testosterone levels did not differ between control and case subjects at baseline and follow-up(both P>0.05).Our results demonstrate that oophorectomy further attenuates estradiol levels below what is achieved by high-dose exogenous testosterone alone.Correlated clinical outcomes,such as impacts on bone health,were not available.The clinical implications of oophorectomy versus ovarian retention on endocrinological and overall health outcomes are currently limited.Sahil Kumar Elise Bertin Cormac O' Dwyer Amir Khorrami Richard Wassersug Smita Mukherjee Neeraj Mehra Marshall Dahl Krista Genoway Alexander G Kavanagh 2023Asian Journal of Andrology2023,25,3:0
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