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| 1 | Endoscopic ultrasonography-guided fine needle aspiration:Relatively low sensitivity in the endosonographer population显示文摘AIM:To assess the characteristics and quality of endoscopic ultrasonography-guided fine needle aspiration(EUS-FNA) in a large panel of endosonographers.METHODS:A survey was conducted during the 13th annual live course of endoscopic ultrasonography(EUS) held in Amsterdam,Netherlands.A 2-page questionnaire was developed for the study.Content validity of the questionnaire was determined based on input by experts in the field and a review of the relevant literature.It contained 30 questions that pertained to demographics and the current practice for EUS-FNA of responders,including sampling technique,sample processing,cytopathological diagnosis and sensitivity of EUS-FNA for the diagnosis of solid mass lesions.One hundred and sixty-one endosonographers who attended the course were asked to answer the survey.This allowed assessing the current practice of EUS-FNA as well as the self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions.We also examined which factors were associated with a self-reported sensitivity of EUS-FNA for the diagnosis of solid mass lesions > 80%.RESULTS:Completed surveys were collected from 92(57.1%) of 161 endosonographers who attended the conference.The endosonographers had been practicing endoscopy and EUS for 12.5 ± 7.8 years and 4.8 ± 4.1 years,respectively;one third of them worked in a hospital with an annual caseload > 100 EUS-FNA.Endoscopy practices were located in 29 countries,including 13 countries in Western Europe that totaled 75.3% of the responses.Only one third of endosonographers reported a sensitivity for the diagnosis of solid mass lesions > 80%(interquartile range of sensitivities,25.0%-75.0%).Factors independently associated with a sensitivity > 80% were(1) > 7 needle passes for pancreatic lesions or rapid on-site cytopathological evaluation(ROSE)(P < 0.0001),(2) a high annual hospital caseload(P = 0.024) and(3) routine isolation of microcores from EUS-FNA samples(P = 0.042).ROSE was routinely available to 27.9% of respondents.For lymph nodes and pancreatic masses,a maximum of three needle passes was performed by approximately two thirds of those who did not have ROSE.Microcores were routinely harvested from EUS-FNA samples by approximately one third(37.2%) of survey respondents.CONCLUSION:EUS-FNA sensitivity was considerably lower than reported in the literature.Low EUS-FNA sensitivity was associated with unavailability of ROSE,few needle passes,absence of microcore isolation and low hospital caseload. | Jean-Marc Dumonceau Thibaud Koessler Jeanin E van Hooft Paul Fockens | 2012 | World Journal of Gastroenterology2012，18，19： | 7 |
| 2 | Prophylaxis of fat and bone marrow embolism in cementedtotal hip arthroplasty显示文摘 | Pitto RP Koessler M | 1998 | Clin Orthop1998，，355： | 1 |
| 3 | Production of histamine, tryamine, brochospastic and artefiospastic substance in blood broth by pure cultures of microorganisms显示文摘 | Koessler K K Hanke M T Sheppard M S | 1928 | Journal of Infectious Diseases1928，3，： | 1 |
| 4 | Optimal delegation with multi-dimensional decisions显示文摘 | Frédéric Koessler David Martimort | 2012 | Journal of Economic Theory2012，，5： | 1 |
| 5 | Common germline varia- tion in mismatch repair genes and survival after a diagnosis of colorectal cancer 显示文摘 | Koessler T Azzato EM Perkins B | 2009 | Int J Cancer2009，124，8： | 1 |
| 6 | The pathololgy of bronch ial asthma显示文摘 | Huber HL Koessler KK | 1922 | A rch Intern Med1922，30，： | 1 |
| 7 | Revisiting games of incomplete information with analogy-based expectations显示文摘 | Jehiel P Koessler F | 2008 | Games and Economic Behavior2008，62，2： | 1 |
| 8 | Comparison of fixation of the femoral component without cement and fixation with use of a bone-vacuum cementing technique for the prevention of fat embolism during THA显示文摘 | Pitto RP Koessler M Joem WK | 1999 | J Bone Joint Surg Am1999，81，6： | 1 |
| 9 | 15 Voltage instability collapse-an overview显示文摘 | Koessler R J | 1997 | IEE Colloquium on Voltage Collapse (Digest No:1997/101)1997，16，： | 1 |
| 10 | The clinical relevance of embolic events detected by transesophageal echocardiography during cemented total hip arthroplasty: a randomized clinical trial 显示文摘 | Koessler M J Fabiani R Hamer H | 2001 | Anesth Analg2001，92，1： | 1 |
| 11 | Challenges to optimal power flow显示文摘 | Momoh J A Koessler R J Bond M S | 1997 | IEEE Trans on Power Systems1997，12，1： | 1 |
| 12 | Intracra?nial evaluation of the epileptogenic zone in regional infrasylvian polymicrogyria显示文摘 | Ramantani G Koessler L Colnat-Coulbois S | 2013 | Epilepsia2013，54，2： | 1 |
| 13 | Influence of source separation and montage on ictal source localization显示文摘 | Koessler L Salido-Ruiz R Ranta R | 2010 | Conf Proc IEEE Eng Med Biol Soc2010，，： | 1 |
| 14 | Comparison of fixation of the femoral component without cement and fixation with use of a bonevacuum cementing technique for the prevention of fat embolism during total hip arthroplasty : A prospective, randomized clinical trial显示文摘 | Pitto RP Koessler M Kuehle JW | 1999 | J Bone Joint Surg Am1999，81，： | 1 |
| 15 | Production of histamine,tryamine,brochospastic and arteriospastic substance in blood broth by pure cultures of microorganisms显示文摘 | Koessler K K Hanke M T Sheppard M S | 1928 | Journal of Infectious Diseases1928，3，： | 1 |
| 16 | Challenges to optimal power flow显示文摘 | Momoh J A Koessler R J Bond M S | 1997 | IEEE Transactions on Power Systems1997，12，1： | 1 |
| 17 | Common germline variation in mismatch repair genes and survival after a diagnosis of colorectalcancer显示文摘 | Koessler T Azzato E M Perkins B | 2009 | Int J Cancer2009，124，8： | 1 |
| 18 | Fat and bone marrow embolism during percutaneous vertebroplasty显示文摘 | Koessler MJ ebli N Pitto RP | 2003 | AnesthAnalg2003，97，1： | 1 |
| 19 | Giant cystic widening of Vichow-Robin space:an anatomo functional study显示文摘 | Mathias J Koessler L Brissart H | 2007 | AJNR2007，28，8： | 1 |
| 20 | The clinic relevance ofembolic events detected by transophageal cardiography during cemented total hip arthroplasty: a randominized clinical trial 显示文摘 | Koessler MJ Fabiani R Hamer H | 2001 | Anesth Analg2001，92，： | 1 |
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