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| 1 | Lovastain-induced cardiac toxicity involve both oncotic and apoptotic cell death with the apoptotic component blunted by bosth caspase-2 and caspase-3 inhibitor显示文摘 | Rabkin SW Klong JY | 2003 | Toxicol Appl Pharmacol2003，193，3： | 1 |
| 2 | Lovastain-induced cardiac toxicity involve both oncotic and apoptoticcell death with the apoptotic component blunted by bosth caspase-2 and caspase-3 inhibitor显示文摘 | Rabkin SW Klong JY | 2003 | Toxieol Appl Pbarmacol2003，193，3： | 1 |
| 3 | Lovastain-induced cardiac toxicity involve both oncotic and apoptotic cell death with the apoptotic component blunted by bosth caspase-2 and caspase-3 inhibitor 显示文摘 | Rabkin SW Klong J Y | 2003 | Toxieol Appl Pharmacol2003，193，3： | 1 |
| 4 | Lovastain-induced cardiac toxicity involve both oncotic and apoptotic cell death with the apoptotic component blunted by bosth caspase-2 and caspase-3 inhibitor 显示文摘 | Rabkin SW Klong J Y | 2003 | Toxicol Appl Pharmacol2003，193，3： | 1 |
| 5 | Systematic development of biomass overproducing Scheffersomyces stipitis for high-cell-density fermentations显示文摘The development of economically feasible bio-based process requires efficient cell factories capable of producing the desired product at high titer under high-cell-density fermentation.Herein we present a combinatorial approach based on systems metabolic engineering and metabolic evolution for the development of efficient biomass-producing strain.Systems metabolic engineering guided by flux balance analysis(FBA)was first employed to rationally design mutant strains of Scheffersomyces stipitis with high biomass yield.By experimentally implementing these mutations,the biomass yield was improved by 30%in GPD1,25%in TKL1,30%in CIT1,and 44%in ZWF1 overexpressed mutants compared to wild-type.These designed mutants were further fine-tuned through metabolic evolution resulting in the maximal biomass yield of 0.49 g-cdw/g-glucose,whichmatcheswell with predicted yield phenotype.The constructed mutants are beneficial for biotechnology applications dealing with high cell titer cultivations.This work demonstrates a solid confirmation of systems metabolic engineering in combination with metabolic evolution approach for efficient strain development,which could assist in rapid optimization of cell factory for an economically viable and sustainable bio-based process. | Pornkamol Unrean Sukanya Jeennor Kobkul Laoteng Thailand Science Park Phahonyothin Road Klong Nueng Klong Luang Thailand | 2016 | Synthetic and Systems Biotechnology2016，1，1： | 0 |
| 6 | 手串吊灯显示文摘现实中珠宝都是人们用来装饰自己的小物件,而瑞典年轻设计师KATRIINA NUUTINEN的作品Hely Lamp则是为居室设计的首饰。这一串像樱桃样悬挂起来的水晶吊灯,给室内营造出舒适惬意的氛围。Hely这款珠宝吊灯由白、蓝、灰、棕四色玻璃球构成,颜色和形状和谐搭配,灯光在玻璃罩内几经反射后映射在玻璃上,洒落一屋的情调。这款首饰灯的珍贵之处还在于,它的制造商Klong公司仅限量生产了200件。 | 柚子 Klong(图) | 2012 | 设计2012，25，5： | 0 |
| 7 | 源于日常,归于寂静显示文摘“不论世间如何动乱,最后终归于寂静;不论万法如何差别,最后终归于平等。”在这个错综复杂、瞬息流变的世界,我们在追求着怎样的设计?有些人无时无刻不在标榜“个性”,热衷于往自己身上贴上各式各样的“标签”,以“标新立异”作为设计的目标:而有些人却选择沉淀内心,体察和感悟身边世界和日常生活的细微变化,在寂静中寻找设计的本质。 | MOEBE Sonia Pedrazzini toumei studio note Swedish Ninja Anna Thorunn Zuzana Holaňová & Martina ?ílová bisqit Alberto Bellamoli Jonathan Hotz 朱妍澔 Bujnie ROY Stephen Roy Besler & Sons Klong Katriina Nuutinen Yoh Komiyama 彭佳 | 2018 | 现代装饰2018，0，6： | 0 |
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