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| 1 | Proteolysis in milk: the significance of proteinases originating from milk leucocytes and a comparison of the action nf leucocute,bacterial and natural milk proteinases on casein显示文摘 | Grieve P A Kitchen B J | 1985 | Journal of Dariy Research1985，52，： | 1 |
| 2 | 显示文摘 | Kitchens C McLeod M C Roberts C B | 2003 | J Phys Chem: B2003，107，11： | 1 |
| 3 | Effects of mastiffs on milk yield, milk composition, processing properties and yield and quality of milk products Aust 显示文摘 | MUNRO E L GRIEVE P A KITCHEN B J | 1984 | Dairy Technol1984，39，： | 1 |
| 4 | Docking and scoring in virtual screening for drug discovery: Methods and applications显示文摘 | DOUGLAS B KITCHEN HLNE D | 2004 | Nat Rev Drug Discov2004，3，11： | 1 |
| 5 | Fluorescent tren-based 4-amino-1,8-naphthalimide sensor for Cu (Ⅱ)based on the use of the (fluorophore-spacer-receptor)photoinduced electron transfer (PET) principle显示文摘 | Veale E B Kitchen J A Gunnlaugsson T | | 0，，2： | 1 |
| 6 | Milk enzymes-their distribution and activity显示文摘 | Kitchen B J Taylor G C White I C | 1970 | Journal of Dairy Research1970，37，27： | 1 |
| 7 | Copper nanoparticle synthesis in compressed liquid and supercritical fluid reverse micelle systems显示文摘 | KITCHENS C L ROBERTS C B | 2004 | Ind Eng Chem Res2004，3，： | 1 |
| 8 | Acutemonoblastic leukemia of infancy in Klinefelter^ syn-drome显示文摘 | FOOT A B’OAKHILL A KITCHEN C | 1992 | Cancer Genetic Cytogenet1992，61，： | 1 |
| 9 | Mastitis diagnostic tests to estimate mammary gland epithelial cell damage显示文摘 | Kitchen B J Middleton G durward I G | 1980 | Journal Dairy Science1980，63，： | 1 |
| 10 | Bovine milk Nacetyle-β-D-gluosaminidase and its significance in the detection of abnormal udder secretions显示文摘 | Kitchen B J Middleton G Salmon M | 1978 | Journal of Dairy Research1978，45，： | 1 |
| 11 | Relationshipbetween the level of N-acetyl-beta-D-glucosaminidase(NAGase)in bovine milk and the presence of mastitis pathogens显示文摘 | KITCHEN B J KWEE W S MIDDLETON G | 1984 | J Dairy Res1984，51，1： | 1 |
| 12 | Role of IL-10 in regulating proinflammatory cytokine release by Kupffer cells following traumahemorrhage显示文摘 | Yokoyama Y Kitchens WC Toth B | 2004 | Am J Physiol Gastrointest Liver Physiol2004，286，6： | 1 |
| 13 | Milk compositional changes and related diagnostic tests显示文摘 | Kitchen B J | | 0，，： | 1 |
| 14 | Upregulation of hepatic prolactin receptor gene expression by 17 beta-estradiol following trauma-hemorrhage 显示文摘 | Yokoyama Y Kitchens WC Toth B | 2003 | J Appl Physiol2003，95，6： | 1 |
| 15 | Dynamics of Non-Ergodic Piecewise Affine Maps of the Torus显示文摘 | Adler R Kitchens B Tresser C | 2001 | Ergod Th & Dynam Sys2001，21，： | 1 |
| 16 | Docking and scoring in virtual screening for drug discovery: methods and applications显示文摘 | Kitchen B Decornez H Furr J R | 2004 | Nat Rev Drug Discov2004，3，11： | 1 |
| 17 | Streptomycin and neo- mycin in veterinary medicine显示文摘 | Kitchen H B Waksman S A | 1955 | American Veterina- ry Medical Association1955，127，942： | 1 |
| 18 | Review of the progress of dairy science: bovine mastitis: milk compositional changes and re- lated diagnostic tests 显示文摘 | Kitchen B J | 1981 | J Dairy Sci1981，48，1： | 1 |
| 19 | 人乳头瘤病毒16/18型AS04佐剂疫苗预防肿瘤基因型HPV引起的宫颈感染和癌前病变的效应(PATRICIA):一项在年轻女性中进行的双盲、随机研究的最终分析显示文摘背景在年轻成人中进行的Ⅲ期随机、双盲对照PATRICIA试验(PApilloma TRial)的事件驱动期中分析显示,人乳头瘤病毒(HPV)16/18AS04佐剂疫苗具有免疫原性,且总体耐受性良好,对HPV16或HPV18感染及相关的癌前病变具有预防效应。本文作者旨在评估最终事件驱动分析中的疫苗效应。方法将在基线、1个月和6个月接种疫苗的15~25岁女性分类为符合方案的效应队列(ATP-E队列;疫苗组8093例,对照组8069例)、总接种队列(TVC;包括至少接种1剂疫苗的所有女性,而不考虑其基线HPV状态;代表普遍的年轻女性人群,包括性活跃者;疫苗组9319例,对照组9325例)和TVC-naive(无证据表明基线时存在肿瘤基因型HPV感染;代表无性行为女性;疫苗组5822例,对照组5819例)。主要终点是。在基线时血清和DNA均为阴性且在6个月时为相应类型(ATP-E队列)的女性中,评估疫苗对HPV16或HPV18相关性宫颈上皮内瘤变≥2级(CIN2+)的预防效应。该试验在ClinicalTrial.gov上的注册编码为NCT00122681.结果第3剂疫苗接种后平均随访34.9个月(s=6.4)。在主要分析中疫苗对HPV16/18相关性CIN2+的预防效应为92.9%(96.1%CI79.9%~98.3%),在对可能因多种肿瘤基因型HPV引起的病变(ATP-E队列)的分析中,其预防效应为98.1%(96.1%CI88.4%~100%)。不考虑病变HPVDNA时,疫苗对CIN2+的预防效应在TVC中为30.4%(96.1%CI16.4%~42.1%),在TVC-naive中为70.2%(96.1%CI54.7%~80.9%);而对CIN3+的相应效应在TVC中为33.4%(96.1%CI9.1%~51.5%).在TVC-naive中为87.0%(96.1%CI54.9%~97.7%).在预防12种非疫苗肿瘤基因型HPv相关性CIN2+的效应为54.0%(96.1%CI34.0%~68.4%:ATP-E队列)。在TVC中可见对HPV31、33和45相关性CIN2+的个体交叉保护效应。结论HPV16/18 AS04佐剂疫苗表现出对HPV16/18和非疫苗肿瘤基因型HPV相关性CIN2+较强的预防效应,而要获得整体预防效应就需要在更广泛的人群中进行大面积强化免疫计划。基金 葛兰素史克。 | J Paavonen P Naud J Salmeron C M Wheeler S-N Chow D Apter H Kitchener X Castellsague J C Teixeira S R Skinner J Hedrick U Jaisamrarn G Limson S Garland A Szarewski B Romanowski F Y Aoki T F Schwarz W A J Poppe F X Bosch D Jenkins K Hardt T Zahaf D Descamps F Struyf M Lehtinen G Dubin 周彩虹(译) | 2009 | 世界临床医学2009，，12： | 1 |
| 20 | GABAB receptor subtypes differentially modulate synaptic inhibition in the dentate gyrus to enhance granule cell output显示文摘 | Foster JD Kitchen I Bettler B et al | 2013 | Br J Pharmacol2013，168，8： | 1 |
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