2篇
您的检索式：作者名="Keyong Tian"
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Radiofrequency field enhanced chemical ionization with vacuum ultraviolet lamp for miniature time-of-flight mass spectrometer显示文摘It is difficult to rapidly and on-line detect trace volatile organic compounds for miniature mass spectrometry due to its limited sampling volume at slow pumping speed. In this paper, we developed a new radiofrequency field enhanced chemical ionization source(RF-ECI) with vacuum ultraviolet(VUV)lamp by coupling radiofrequency electric field and direct-current field together. The experiment results showed that the sensitivity of benzene, toluene, hydrogen sul fide and other compounds increased by 2–3 orders of magnitude under the introduction of RF-ECI comparing to traditional single photon ionization(SPI). At the same time, the reagent ion of O_2^+realized the charge transfer reaction chemical ionization,and the RF-ECI effectively expanded the detection range of the VUV lamp based SPI. The VUV lamp has inherent advantages in the on-site analytical instrument for its small size and low power consumption,and the VUV lamp based RF-ECI miniature time-offlight mass spectrometer(TOFMS) has a limit-ofdetection for H_2S as low as 0.0571 mg/m^3, and it is expected to be used widely in the field of on-site rapid analysis. | Lijuan Zhou Jichun Jiang Kun Zhao Jinxu Li Chenxin Wu Haiyang Li Di Tian Keyong Hou | 2018 | Chinese Chemical Letters2018，29，5： | 1 |
| 2 | Translocation of telomerase reverse transcriptase coincided with ATP release in postnatal cochlear supporting cells显示文摘The spontaneous bursts of electrical activity in the developing auditory system are derived from the periodic release of adenosine triphosphate(ATP)by supporting cells in the Kölliker’s organ.However,the mechanisms responsible for initiating spontaneous ATP release have not been determined.Our previous study revealed that telomerase reverse transcriptase(TERT)is expressed in the basilar membrane during the first postnatal week.Its role in cochlear development remains unclear.In this study,we investigated the expression and role of TERT in postnatal cochlea supporting cells.Our results revealed that in postnatal cochlear Kölliker’s organ supporting cells,TERT shifts from the nucleus into the cytoplasm over time.We found that the TERT translocation tendency in postnatal cochlear supporting cells in vitro coincided with that observed in vivo.Further analysis showed that TERT in the cytoplasm was mainly located in mitochondria in the absence of oxidative stress or apoptosis,suggesting that TERT in mitochondria plays roles other than antioxidant or anti-apoptotic functions.We observed increased ATP synthesis,release and activation of purine signaling systems in supporting cells during the first 10 postnatal days.The phenomenon that TERT translocation coincided with changes in ATP synthesis,release and activation of the purine signaling system in postnatal cochlear supporting cells suggested that TERT may be involved in regulating ATP release and activation of the purine signaling system.Our study provides a new research direction for exploring the spontaneous electrical activity of the cochlea during the early postnatal period. | Yukai Zhang Keyong Tian Wei Wei Wenjuan Mi Fei Lu Zhenzhen Liu Qingwen Zhu Xinyu Zhang Panling Geng Jianhua Qiu Yongli Song Dingjun Zha | 2024 | Neural Regeneration Research2024，19，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员