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| 1 | Risk factors for bleeding after endoscopic submucosal dissection for gastric lesions显示文摘AIM:To assess risk factors for bleeding after gastric endoscopic submucosal dissection(ESD) and to develop preventive measures.METHODS:This retrospective study was performed in a tertiary referral center.A total of 328 patients underwent ESD for 398 gastric neoplasms between July 2007 and June 2009.The main outcome was association between post-ESD bleeding and the following:age;sex;comorbidities;daily use of medicine potentially related to gastric injury/bleeding;location,size,and histological depth of lesions;ulceration;experience of operator coagulating the ulcer floor,and duration of operation.We also determined the relationship between the location of post-ESD bleeding and risk factors for hemorrhage.RESULTS:Univariate analysis revealed significant risk factors:tumor location [odds ratio(OR),2.86;95% CI:1.21-6.79,P=0.024],coagulator experience(OR,4.29;95% CI:1.43-12.86,P=0.009),and medicine potentially related to gastric injury/bleeding(OR,2.80;95% CI:1.14-6.90,P=0.039).Multivariate logistic regression analysis confirmed significant,independent risk factors:tumor in lower third of stomach(OR,2.47;95% CI:1.02-5.96,P=0.044),beginner coagulator(OR,3.93;95% CI:1.29-11.9,P=0.016),and medicine(OR,2.76;95% CI:1.09-6.98,P=0.032).We classif ied cases of post-ESD bleeding into two groups(bleeding at the ulcer margin vs bleeding at the center) and found that bleeding at the margin occurred more frequently with beginner coagulators compared with experts(OR,16.00;95% CI:1.22-210.59,P=0.040).CONCLUSION:Beginner coagulators,tumor in the antrum,and medicines were significant risk factors for post-ESD bleeding.Bleeding at the ulcer margin frequently occurred with beginner operators. | Yosuke Tsuji Ken Ohata Takafumi Ito Hideyuki Chiba Tomohiko Ohya Toshiaki Gunji Nobuyuki Matsuhashi | 2010 | World Journal of Gastroenterology2010，16，23： | 60 |
| 2 | 癌症康复评价系统简表中文版的信度和效度显示文摘目的考察癌症患者生命质量评定工具“癌症康复评价简表”(CARES-SF)中文版的信度和效度。方法采用“WHO-QOL跨文化生命质量研究问卷翻译法”对CARES-SF进行系统翻译和评价,并应用中文版CARES-SF对146名恶性肿瘤患者的生命质量进行调查,并在6个月后对其中的107名患者进行生命质量随访。结果CARES-SF中文版重测信度为0.81,内部一致性为0.66-0.93,与症状困扰程度、焦虑、抑郁评分之间的相关系数分别为0.46,0.43,0.49(P<0.01);因素分析得到9个因素,各条目负载大于0.4,该9个因素共解释了66.82%的方差,基本证实了其结构效度;该量表能区分出不同类型的癌症患者生命质量之间的差异,以及同一患者生命质量在6个月中的纵向变化。结论CARES-SF中文版是一份具有较好信度和效度的癌症患者生命质量评定量表,可应用与肿瘤临床和科研。 | 胡雁 Ken Sellick | 2006 | 中国心理卫生杂志2006，20，2： | 51 |
| 3 | Portal vein thrombosis in liver cirrhosis显示文摘Portal vein thrombosis(PVT) is considered to be a frequent complication of liver cirrhosis. However, unlike PVT in patients without cirrhosis, very few data are available on the natural history and management of PVT in cirrhosis, despite its association with potentially life-threatening conditions, such as gastroesophageal bleeding and acute intestinal ischemia. Moreover, no consensus regarding PVT in cirrhosis exists. Suggested causes of PVT in cirrhosis include reduced portal blood flow velocity, multiple congenital or acquired thrombophilic factors, inherited or acquired conditions, and derangement of liver architecture. However, the understanding of PVT in cirrhosis is incomplete. In addition, information on the management of PVT in cirrhosis is inadequate. The aims of this review are to:(1) assemble data on the physiopathological mechanism, clinical findings, diagnosis and management of PVT in cirrhosis;(2) describe the principal factors most frequently involved in PVT development; and(3) summarize the recent knowledge concerning diagnostic and therapeutic procedures. | Nao Kinjo Hirofumi Kawanaka Tomohiko Akahoshi Yoshi-hiro Matsumoto Masahiro Kamori Yoshihiro Nagao Naotaka Hashimoto Hideo Uehara Morimasa Tomikawa Ken Shirabe Yoshihiko Maehara | 2014 | World Journal of Hepatology2014，6，2： | 38 |
| 4 | 互动元话语:学术语境变迁中的论辩与修辞显示文摘元话语是作者组织语篇、表达对概念和读者的态度与评价,是构建学术互动的重要资源。本文采用元话语的人际视角,考察互动类元话语标记50年间(1965-2015)在不同学科学术论文中的历时变化。基于源自文理四个学科期刊论文的自建语料库(约220万词符),研究发现互动类元话语资源呈下降趋势,人文及社会科学领域逐渐减少元话语的使用,而理工学科则不断增加元话语的投入。这反映出学术论辩与话语实践随社会文化等语境变迁而发生变化,同时本文也对学术写作和学术英语教学提供重要的启示。 | 姜峰 Ken Hyland | 2020 | 外语教学2020，41，2： | 31 |
| 5 | 老年人重要社会支持的特点及其与老化态度的关系显示文摘采用重要他人和老化态度问卷测查了441名老年人的社会支持和老化态度情况,并且从支持的数量和质量角度以及实际支持和期望支持的角度细致考察了社会支持与老化态度的关系。结果表明:(1)老年人的支持来源符合层级补偿模型;(2)不同性别、年龄及受教育水平的老年人在重要社会支持上存在显著差异;(3)老年人从重要他人那里获得的实际社会支持的质量越高,老化态度越积极。 | 张明妍 王大华 Mick Power Ken Laidlaw | 2011 | 心理科学2011，34，2： | 29 |
| 6 | Cancer-associated fibroblasts in hepatocellular carcinoma显示文摘The hepatic stellate cells in the liver are stimulated sustainably by chronic injury of the hepatocytes, activating myofibroblasts, which produce abundant collagen. Myofibroblasts are the major source of extracellular proteins during fibrogenesis, and may directly, or secreted products, contribute to carcinogenesis and tumor progression. Cancer-associated fibroblasts(CAFs) are one of the components of the tumor microenvironment that promote the proliferation and invasion of cancer cells by secreting various growth factors and cytokines. CAFs crosstalk with cancer cells stimulates tumor progression by creating a favorable microenvironment for progression, invasion, and metastasis through the epithelial-mesenchymal transition. Basic studies on CAFs have advanced, and the role of CAFs in tumors has been elucidated. In particular, for hepatocellular carcinoma, carcinogenesis from cirrhosis is a known fact, and participation of CAFs in carcinogenesis is supported. In this review, we discuss the current literature on the role of CAFs and CAF-related signaling in carcinogenesis, crosstalk with cancer cells, immunosuppressive effects, angiogenesis, therapeutic targets, and resistance to chemotherapy. The role of CAFs is important in cancer initiation and progression. CAF-targeted therapy may be effective for suppression not only of fibrosis but also cancer progression. | Norio Kubo Kenichiro Araki Hiroyuki Kuwano Ken Shirabe | 2016 | World Journal of Gastroenterology2016，22，30： | 25 |
| 7 | 多频海底声学原位测试系统研制和试用显示文摘海底沉积物的声学特性(最重要的是声速和声衰减)以及它们与物理(包括土力学)特性之间的关系是沉积物声学中两个重要的研究项目.介绍了新研制的实时监控多频海底声学原位测试系统.该系统可测量浅表层沉积物的声速.探测频率为8,10,12,15kHz,可根据实际情况选择发射波形、接收增益和采样长度,采样率为0.5~2.0MHz,工作水深为300m.系统具有倾斜传感器、8通道扩充等功能.用该系统在杭州湾测得了四种频率的沉积物原位声速. | 陶春辉 金肖兵 金翔龙 周建平 张金辉 顾春华 何拥华 WIL KENS R H FU Shung-sheng | 2006 | 海洋学报2006，28，2： | 23 |
| 8 | Benefits of early postoperative jejunal feeding in patients undergoing duodenohemipancreatectomy显示文摘瞄准:学习早手术后的肠内的营养是否减少复杂并发症的发生或改进营养的地位追随者 duodenohemipancreatectomy (DHP ) 。方法:我们学习了为一个 peri-ampullary 团经历了 DHP 的 39 个病人。23 个病人收到了全部的父母营养然后开始有在手术后的白天(邮政部门) 之间的营养的口头的吸入 7 和 14 [晚手术后的肠内的营养(LPEN ) 组] 。十六个病人开始有肠内的在手术以后整个空肠造口术导管日子喂[早手术后的肠内的营养(EPEN ) 组] 。在早手术后的阶段的复杂并发症和实验室数据的发生在在 LPEN 和 EPEN 组之间的比较被学习。结果:在 EPEN 组的白朊和全部的蛋白质的浆液层次比在 LPEN 组的那些显著地高。身体团索引的损失显著地作为与 LPEN 组相比在 EPEN 组被压制。在操作比在 LPEN 组在 EPEN 组更快显著地被恢复以后,淋巴细胞计数立即减少了。EPEN 组显著地比 LPEN 组显示出手术后的胰腺的管,以及住院的显著地更短的长度的更少发生。在在二个组之间的另外的手术后的复杂并发症的发生没有有效差量,例如推迟的胃的倒空,外科的地点感染,胆管炎,和小肠阻塞。结论:EPEN 是为为一个 peri-ampullary 团经历了 DHP 的病人的一个安全、有益的机会。 | Takehiro Okabayashi Michiya Kobayashi Isao Nishimori Tekeki Sugimoto Toyokazu Akimori Tsutomu Namikawa Ken Okamoto Saburo Onishi Keijiro Araki | 2006 | World Journal of Gastroenterology2006，12，1： | 23 |
| 9 | AZF microdeletions and partial deletions of AZFc region on the Y chromosome in Moroccan men显示文摘瞄准:第一次评估 Y 染色体的频率,并且讨论 AZF 删除的临床的意义微删除和在摩洛哥的人的 AZFc 区域的部分删除的出现。方法:我们屏蔽了 Y 染色体微删除和不肥沃的人的一个连续的组的 AZFc 区域的部分删除(n = 149 ) 并且控制(100 个肥沃的人, 76 个 normospermic 人) 。AZFa, AZFb, AZFc 和 AZFc 区域的部分删除被聚合酶链反应(PCR ) 根据确定的协议分析。结果:在为微删除屏蔽的 127 个不肥沃的人之中,四个题目被发现有微删除:二 AZFc 删除和二 AZFb+AZFc 删除。所有删除仅仅在 azoospermic 题目被发现(4/48, 8.33%) 。全面 AZFc 删除频率是低的(4/127, 3.15%) 。AZF 微删除没在 oligoasthenoteratozoospermia (燕麦) 或控制被观察。AZFc (gr/gr ) 的部分删除总共部分 AZFc 删除(gr/gr ) 在控制组被发现的 149 个不肥沃的人(4.70%) 中的 7 个和 7 的被观察(7/176, 3.98%) 。另外,二 b2/b3 删除在二个 azoospermic 题目被识别(2/149, 1.34%) 然而并非在控制组。结论:我们的结果建议 Y 染色体 AZF 微删除的频率与严重 spermatogenic 失败在个人被提高并且 gr/gr 删除没与 spermatogenic 失败被联系。 | Laila Imken Brahim El Houate Abdelaziz Chafik Halima Nahili Redouane Boulouiz Omar Abidi Elbakkay Chadli Noureddine Louanjli Abdelouhab Elfath Mohammed Hassar Ken McElreavey Abdelhamid Barakat Hassan Rouba | 2007 | Asian Journal of Andrology2007，9，5： | 22 |
| 10 | 消化道恶性肿瘤病人确诊初期生命质量纵向研究显示文摘目的探讨消化道恶性肿瘤病人确诊初期生命质量的纵向变化 ,为针对性护理干预提供理论依据。方法采用癌症康复评价简表 (CARES SF)、MSAS量表、社会支持评定量表、状态焦虑自评量表、贝克抑郁量表对 10 7例消化道恶性肿瘤病人进行 6个月的追踪调查。结果生命质量中生理、心理社会及与医务人员的关系评分在 6个月中较稳定 (均数变化 ,P >0 .0 5 ,相关性分析 ,P <0 .0 1) ;婚姻关系、性功能评分均显著增加 (均P <0 .0 1)。确诊初期的生命质量、疾病时间长短、性别、教育层次是 6个月后生命质量的预测变量 (P <0 .0 5 ,P <0 .0 1)。结论病人确诊初期的生命质量为中等 ,6个月后婚姻关系、性功能问题加重 ;生命质量的影响因素为确诊初期的生命质量、疾病时间长短、性别、教育层次。制订针对性的干预方案可望提高病人的生命质量。 | 胡雁 Ken Sellick | 2003 | 护理学杂志(综合版)2003，18，10： | 22 |
| 11 | Evaluation of the effect of pyrrolidine dithiocarbamate in suppressing inflammation in mice with dextran sodium sulfate-induced colitis显示文摘AIM: To evaluate the effect of pyrrolidine dithio- carbamate (PDTC; an NF-κB inhibitor) administered at low (50 mg/kg) and high (100 mg/kg) doses in suppressing colitis in mice with dextran sodium sulfate (DSS)-induced colitis. METHODS: Mice were divided into a DSS-untreated group (normal group), DSS-treated control group, DSS+PDTC-treated groupⅠ(low-dose group), and DSS+PDTC-treated groupⅡ (high-dose group). In each group, the disease activity index score (DAI score), intestinal length, histological score, and the levels of activated NF-κB and inflammatory cytokines (IL-1β and TNF-α) in tissue were measured. RESULTS: The DSS+PDTC-treated groupⅡ exhibited suppression of shortening of intestinal length and reduction of DAI score. Activated NF-κB level and IL-1β and TNF-α levels were significantly lower in DSS+PDTC- treated groupⅡ. CONCLUSION: These findings suggest that PDTC is useful for the treatment of ulcerative colitis. | Ichiro Hirata Shingo Yasumoto Ken Toshina Takuya Inoue Takashi Nishikawa Naoko Murano Mitsuyuki Murano Fang-Yu Wang Ken-ichi Katsu | 2007 | World Journal of Gastroenterology2007，13，11： | 20 |
| 12 | Diagnostic and therapeutic single-operator cholangiopancreatoscopy in biliopancreatic diseases:Prospective multicenter study in Japan显示文摘AIM: To assess the utility and safety of single-operator cholangiopancreatoscopy(SOCPS) using the Spy Glass system in widespread clinical application for biliary and pancreatic diseases.METHODS: This study was a prospective case series conducted in 20 referral centers in Japan. There were 148 patients who underwent SOCPS; 124 for biliary diseases and 24 for pancreatic diseases. The attempted interventions were SOCPS examination, SOCPS-directed tissue sampling, and therapy for stone removal, among others. The main outcomes were related to the procedure success rate in terms of visualizing the target lesions, SOCPS-directed adequate tissue sampling, and complete stone removal. RESULTS: A total of 148 patients were enrolled for the diagnosis of indeterminate biliary and pancreatic lesions or treatment of biliary and pancreatic disease. The overall procedure success rate of visualizing the target lesions was 91.2%(135/148). The overall procedural success rates of visualizing the target lesions of diagnostic SOCPS in the bile duct and pancreatic duct were 95.5%(84/89) and 88.2%(15/17), respectively. Diagnosis: the overall adequate tissue for histologic examination was secured in 81.4% of the 86 patients who underwent biopsy under SOCPS(bile duct, 60/75, 80.0%; pancreatic duct, 10/11, 90.9%). The accuracy of histologic diagnosis using SOCPS-directed biopsies in indeterminate bile duct lesions was 70.7%(53/75). In the pancreatic duct, the accuracy of SOCPS visual impression of intraductal papillary mucinous neoplasm was 87.5%(14/16). Stone therapy: complete biliary and pancreatic stone clearance combined with SOCPS-directed stone therapy using electrohydraulic lithotripsy or laser lithotripsy was achieved in 74.2%(23/31) and 42.9%(3/7) of the patients, respectively. Others: SOCPS using the Spy Glass system was used in cannulation of the cystic duct in two patients and for passing across the obstructed self-expandable metallic stent for a malignant biliary stricture in two patients. All procedures were successful in both SOCPS-guided therapies. The incidence of procedure-related adverse events was 5.4%(8/148). CONCLUSION: SOCPS with direct visualization and biopsy for diagnosis and SOCPS-directed therapy for biliary and pancreatic diseases can be safely performed with a high success rate. | Toshio Kurihara Ichiro Yasuda Hiroyuki Isayama Toshio Tsuyuguchi Taketo Yamaguchi Ken Kawabe Yoshinobu Okabe Keiji Hanada Tsuyoshi Hayashi Takao Ohtsuka Syuhei Oana Hiroshi Kawakami Yoshinori Igarashi Kazuya Matsumoto Kiichi Tamada Shomei Ryozawa Hiroki Kawashima Yutaka Okamoto Iruru Maetani Hiroyuki Inoue Takao Itoi | 2016 | World Journal of Gastroenterology2016，22，5： | 20 |
| 13 | Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis显示文摘AIM: To evaluate the effi cacy of continuous regional arterial infusion therapy (CRAI) with gabexate mesilate and antibiotics for severe acute pancreatitis (SAP). METHODS: We conducted a prospective study on patients who developed SAP with or without CRAI. Out of 18 patients fulf illed clinical diagnostic criteria for SAP in Japan, 9 patients underwent CRAI, while 9 patients underwent conventional systemic protease inhibitor and antibiotics therapy (non-CRAI). CRAI was initiated within 72 h of the onset of pancreatitis. Gabexate mesilate (2400 mg/d) was continuously administered for 3 to 5 d. The clinical outcome including serum infl ammation-related parameters were examined. RESULTS: The duration of abdominal pain in the CRAI group was 1.9 ± 0.26 d, whereas that in the non-CRAI group was 4.3 ± 0.50. The duration of SIRS in the CRAI group was 2.2 ± 0.22 d, whereas that in the non- CRAI group was 3.2 ± 0.28. Abdominal pain and SIRS disappeared signifi cantly in a short period of time after the initiation of CRAI using gabexate mesilate. The average length of hospitalization signifi cantly differed between the CRAI and non-CRAI groups, 53.3 ± 7.9 d and 87.4 ± 13.9 d, respectively. During the first two weeks, levels of serum CRP and the IL6/IL10 ratio in the CRAI group tended to have a rapid decrease compared to those in the non-CRAI group. CONCLUSION: The present results suggest that CRAI using gabexate mesilate was effective against SAP. | Yoshifumi Ino Yoshiyuki Arita Tetsuro Akashi Toshinari Kimura Hisato Igarashi Takamasa Oono Masayuki Furukawa Ken Kawabe Keiichiro Ogoshi Jiro Ouchi Toshihiko Miyahara Ryoichi Takayanagi Tetsuhide Ito | 2008 | World Journal of Gastroenterology2008，14，41： | 20 |
| 14 | 审计专业判断研究:有关研究的回顾及在中国研究的机遇所在显示文摘本文指出了审计专业判断在审计工作中的重要性所在,分析了审计专业判断研究的目的并对审计专业判断的研究的种类及方法进行了一次全面的回顾。。在本文中,主要讨论下述几个领域的有关研究问题:审计政策的把握、集体决策的制定、知识与记忆方式的研究,及审计环境因素问题。本文还讨论了上述领域的问题在中国学术研究中的机遇所在。 | 肯·T·陶特曼(Ken T.Trotman) 陆正飞(译) 邱寒(译) | 1999 | 中国会计与财务研究1999，，1： | 20 |
| 15 | 两广交界地区S型花岗岩中麻粒岩包体的特征和成因显示文摘粤西南和桂东南地区S型花岗岩中的麻粒岩包体属于同源包体。麻粒岩具有斜长石+石英+黑云母+紫苏辉石±石榴石±钾长石的矿物组合,其稀土总量(135.95~268.83μg/g)和轻重稀土比值(1.85~5.70)变化不大,稀土配分模式一致,且与下地壳相似。同时,它们的铷锶等时线年龄为638~813Ma,锶同位素初始比值为0.7151~0.7152。岩石变质峰期的温度和压力经估算为781~883℃和0.527~0.709GPa,与中下地壳的温压对应。上述资料表明本区的麻粒岩是形成于晚元古代前后的中下地壳产物。此外,岩相学、矿物学和地球化学方面的证据还表明,粤西南地区的麻粒岩是由热穹隆影响下的区域变质作用形成的。 | 杜杨松 Ken D.Collerson 赵建新 庞保成 | 1999 | 岩石学报1999，15，2： | 20 |
| 16 | 中国传统文化的负效应——中文作文法对英文作文法的影响显示文摘一人们往往把两种语言中类似的说法或概念等同起来。例如,人们常把汉语中“单位”一词与英语中的“place of work”(工作地点)相提并论。其实,汉语中“单位”不光是指任职的公司,机关等。对一个中国人来说,“单位”也可能就是家庭住址,也是领导们决定给不给你加薪,让不让你升官,甚至决定让不让你出国,结婚,生孩子的地方。然而,“单位”这个概念也许还不难解释,一般不会引起误解。 | Ken Keobke 张煤 | 1995 | 外语教学理论与实践1995，，3： | 20 |
| 17 | Management of thrombocytopenia due to liver cirrhosis:A review显示文摘Thrombocytopenia is a common complication in liver disease and can adversely affect the treatment of liver cirrhosis,limiting the ability to administer therapy and delaying planned surgical/diagnostic procedures because of an increased risk of bleeding.Multiple factors,including splenic sequestration,reduced activity of the hematopoietic growth factor thrombopoietin,bone marrow suppression by chronic hepatitis C virus infection and anti-cancer agents,and antiviral treatment with interferon-based therapy,can contribute to the development of thrombocytopenia in cirrhotic patients.Of these factors,the major mechanisms for thrombocytopenia in liver cirrhosis are(1)platelet sequestration in the spleen;and(2)decreased production of thrombopoietin in the liver.Several treatment options,including platelet transfusion,interventional partial splenic embolization,and surgical splenectomy,are now available for severe thrombocytopenia in cirrhotic patients.Although thrombopoietin agonists and targeted agents are alternative tools for noninvasively treating thrombocytopenia due to liver cirrhosis,their ability to improve thrombocytopenia in cirrhotic patients is under investigation in clinical trials.In this review,we propose a treatment approach to thrombocytopenia according to our novel concept of splenic volume,and we describe the current management of thrombocytopenia due to liver cirrhosis. | Hiromitsu Hayashi Toru Beppu Ken Shirabe Yoshihiko Maehara Hideo Baba | 2014 | World Journal of Gastroenterology2014，20，10： | 19 |
| 18 | Chitosan and chemically modified chitosan beads for acid dyes sorption显示文摘The capabilities of chitosan and chitosan-EGDE(ethylene glycol diglycidyl ether) beads for removing Acid Red 37(AR 37) and Acid Blue 25(AB 25) from aqueous solution were examined.Chitosan beads were cross-linked with EGDE to enhance its chemical resistance and mechanical strength.Experiments were performed as a function of pH,agitation period and concentration of AR 37 and AB 25.It was shown that the adsorption capacities of chitosan for both acid dyes were comparatively higher than those of chitosan-EGDE.This is mainly because cross-linking using EGDE reduces the major adsorption sites-NH3+ on chitosan.Langmuir isotherm model showed the best conformity compared to Freundlich and BET.The kinetic experimental data agreed very well to the pseudo second-order kinetic model.The desorption study revealed that after three cycles of adsorption and desorption by NaOH and HCl,both adsorbents retained their promising adsorption abilities.FT-IR analysis proved that the adsorption of acid dyes onto chitosan-based adsorbents was a physical adsorption.Results also showed that chitosan and chitosan-EGDE beads were favourable adsorbers and could be employed as low-cost alternatives for the removal of acid dyes in wastewater treatment. | AZLAN Kamari WAN SAIME Wan Ngah LAI KEN Liew | 2009 | Journal of Environmental Sciences2009，21，3： | 18 |
| 19 | 消化道恶性肿瘤患者焦虑和抑郁及生命质量追踪调查显示文摘目的 :调查初期诊断的消化道恶性肿瘤患者半年中的焦虑和抑郁情绪和生命质量变化。方法 :采用SAI、BDI -13和CARES -SF对 14 6名初期诊断的消化道恶性肿瘤患者的情绪特征和生命质量进行为期半年的追踪调查。结果 :初期诊断的消化道恶性肿瘤患者的生命质量为中等 ,焦虑得分和生命质量大多数维度得分在半年中较稳定 ,但半年后患者的抑郁程度加重 ,生命质量的婚姻关系维度、性关系维度得分下降。结论 :初期诊断的消化道恶性肿瘤患者存在明显的情绪障碍 ,应持续评估其心理状态 ,并制订有针对性的干预方案 ,以提高肿瘤患者的生命质量。 | 胡雁 Ken Sellick | 2003 | 中国心理卫生杂志2003，17，12： | 18 |
| 20 | Urgent endoscopic ultrasound-guided choledochoduodenostomy for acute obstructive suppurative cholangitis-induced sepsis显示文摘Acute obstructive suppurative cholangitis(AOSC) due to biliary lithiasis is a life-threatening condition that requires urgent biliary decompression. Although endoscopic retrograde cholangiopancreatography(ERCP) with stent placement is the current gold standard for biliary decompression, it can sometimes be difficult because of failed biliary cannulation. In this retrospective case series, we describe three cases of successful biliary drainage with recovery from septic shock after urgent endoscopic ultrasound-guided choledochoduodenostomy(EUS-CDS) was performed for AOSC due to biliary lithiasis. In all three cases, technical success in inserting the stents was achieved and the patients completely recovered from AOSC with sepsis in a few days after EUS-CDS. There were no procedure-related complications. When initial ERCP fails, EUS-CDS can be an effective life-saving endoscopic biliary decompression procedure that shortens the procedure time and prevents post-ERCP pancreatitis, particularly in patients with AOSC-induced sepsis. | Kosuke Minaga Masayuki Kitano Hajime Imai Kentaro Yamao Ken Kamata Takeshi Miyata Shunsuke Omoto Kumpei Kadosaka Tomoe Yoshikawa Masatoshi Kudo | 2016 | World Journal of Gastroenterology2016，22，16： | 18 |
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