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| 1 | Revised recommenda- tions on screening for chloroquine and hydroxychloroquine reti- nopathy显示文摘 | Marmor M F Kenner U Lai T Y | 2011 | Ophthalmology2011，118，2： | 1 |
| 2 | How fast can you change you mind? The speed of top-down guidance in visual search显示文摘 | WOLFE J M HOROWITZ T S KENNER N | 2004 | Vision Research2004，44，12： | 1 |
| 3 | Rare Items Often Missed in Visual Searches 显示文摘 | Wolfe J M Horowitz T S Kenner N M | 2005 | Nature2005，435，7401： | 1 |
| 4 | Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects 显示文摘 | Kenner L Hoebertz A Beil T | 2004 | J Cell Biol2004，164，4： | 1 |
| 5 | Ability of the no - reflow phenomenon during an acute myocardial infarction to predict left ventricular dysfunction at one - month follow - up显示文摘 | Kenner M D Zajac E J Kondos G T | 1995 | Am J Cardiol1995，76，： | 1 |
| 6 | Numerical Blood Flow an Alysis: Arterial Bit~arcation with a saccular Aneurysm 显示文摘 | PerktoId K Kenner T | 1988 | Basic Res Cardiol1988，83，： | 1 |
| 7 | SO2 removal by NH3 gas injection:effects of temperature and moisture content显示文摘 | Hsunling B Biswas P Kenner T C | 1994 | Indus & Eng Chem Research1994，33，3： | 1 |
| 8 | Gas-chromatographic separation of chlorosilanes,methyichlorosilanes,and associated siloxanes显示文摘 | Burson K R Kenner C T | 1969 | Analyt-ical Chemistry1969，41，6： | 1 |
| 9 | Rare Items Often Missed in Visual Searches 显示文摘 | Wolfe J M Horowitz T S Kenner N M | 2005 | Nature2005，435，1： | 1 |
| 10 | Ability of the no-reflow phenomenon during an acute myocardial infarction to predict left ventricular dysfunction at one-month follow- up显示文摘 | KENNER M ZAJAC E J KONDOS G T | 1995 | Am J Cardiol1995，76，： | 1 |
| 11 | Numerical blood flow analysis: Arterial bifurcation with a saccular aneurysm 显示文摘 | Pepktold K Kenner T Ilbert D | 1998 | Basic ResCardiol1998，83，1： | 1 |
| 12 | Numerical blood flow analysis: arterial bifurcation with asaccular aneurysm 显示文摘 | PEPKTOLD K KENNER T ILBERT D | 1998 | Basic Res Cardiol1998，83，1： | 1 |
| 13 | In vivo functional requirement of the mouse ifitml gene for germ cell develop- ment,interferon mediated immune response and somitogenesis 显示文摘 | KLYMIUK I KENNER L ADLER T | 2012 | PLoS One2012，7，44： | 1 |
| 14 | Rare items often missed in visual searches显示文摘 | Wolfe J M Horowitz T S Kenner N M | 2005 | Nature2005，435，1： | 1 |
| 15 | Flow and stress characteristics in rigid walled compliant carotid artery bifurcation models 显示文摘 | Perktold K Thumer E Kenner T | 1994 | Medical and Biological Engg and Computing1994，32，： | 1 |
| 16 | Abuse-related effects of synthetic cathinones:importance of DAT/SERT relationships显示文摘OBJECTIVE Wide spread abuse of synthetic cathinones found in bath salts preparations has resulted in regulation of some cathinones internationally.Chemists skirt these laws by altering the chemical structures of first-generation cathinones(ie,MDPV,methylone,and mephedrone),resulting in second-generation cathinones(eg,α-PVP,α-PPP,MDPPP,and MDPBP).Although MDPV is a more effective reinforcer than cocaine,little is known about the reinforcing effectiveness of secondgeneration cathinones.To test the hypothesis that synthetic cathinones with higher selectivity for DAT relative to SERT are more effective reinforcers.METHODS Monoamine transporter inhibition was determined using synaptosomes prepared from rat brains.The relative reinforcing effectiveness of intravenously self-administered MDPV,MDPBP,MDPPP,α-PVP,α-PPP,and cocaine were directly compared through evaluations of (1)dose-response curves under a progressive ratio(PR)schedule of reinforcement and (2)demand curves obtained for each drug in male Sprague-Dawley rats.RESULTS Rank order selectivity for DAT/SERT wasα-PVP>MDPV>α-PPP≈MDPBP>MDPPP>cocaine.Comparisons of the maximum number of infusions obtained under a PR schedule of reinforcement(α-PVP>MDPV>α-PPP>MDPBP≈MDPPP>cocaine)and the essential value obtained for each drug in demand analyses(α-PVP>MDPV>α-PPP≈MDPBP≈MDPPP>cocaine)suggest relative reinforcing effectiveness is related to DAT/SERT selectivity.CONCLUSION These data provide evidence that DAT/SERT selectivity accounts for select synthetic cathinones functioning as more effective reinforcers than cocaine and may predict the abuse-related effects of novel synthetic cathinones in humans. | Brenda M GANNON Michael H BAUMANN Kenner C RICE Gregory T COLLINS | 2017 | 中国药理学与毒理学杂志2017，31，10： | 0 |
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