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31篇 您的检索式：作者名="Kalgutkar AS"

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	题名	作者	年代	出处	被引量
1	Drug metabolites as cytochrome p450 inhibitors: a retrospective analysis and proposed algorithm for evaluation of the pharmacokinetic interaction potential of metabolites in drug discovery and development 显示文摘	Callegari E Kalgutkar AS Leung L	2013	Drug Metab Dispos2013，41，12：	1
2	Aspirin-like molecules that covalently inactivate cyclooxygenase-2显示文摘	Kalgutkar AS Crews BC Rowlinson SW	1998	Science1998，280，5367：	1
3	Metabolic activation in drug-induced liver injury显示文摘	Leung L Kalgutkar AS Obach RS	2012	Drug Metab Rev2012，44，1：	1
4	Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inbibitors显示文摘	Kalgutkar AS Crews BC Rowlinson SW	2000	Proc Natl Acad Sci USA2000，97，3：	1
5	Ester and amidederivatives of the nonsteroidal anti-inflammatory drug,indomethacin, as selective cyclooxygenase-2 inhibitors显示文摘	Kalgutkar AS Marnett AB Crews BC	2000	J Med Chem2000，43，2：	1
6	Aspirin - like molecules that covalendy inactivate cyclooxygenase - 2 显示文摘	Kalgutkar AS Crews BC Rowlinson SW	1998	Science1998，280，5367：	1
7	Biotransfor?mation reactions of five-membered aromatic heterocyclic rings显示文摘	Dalvie DK Kalgutkar AS Khojasteh-Bakht SC	2002	Chem Res Toxicol2002，15，3：	1
8	Biochemically based design of eyclooxygenase-2(COX-2) inhibitors : facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors显示文摘	Kalgutkar AS Caews BC Rowlinson SW	2000	Proc Natl Acad Sci USA2000，97，92：	1
9	Ester and amide derivatives of the nonsteroidal anti inflammatory drug,indomethacin,as selective cyclooxygenase-2 inhibitors显示文摘	Kalgutkar AS Marrnet AB Craws BC	2000	J Med Chem2000，43，15：	1
10	Aspirin-like molecules that covalently inactivate cyclooxygenase-2显示文摘	Kalgutkar AS Crews BC Rowlinson SW	1998	Science1998，280，12：	1
11	Covalent modification of cyclooxygenase-2(COX-2) by 2-acetoxyphenyl alkyl sulfides,a new class of selective COX-2 inactivators显示文摘	Kozak KR Crews BC	1998	J Med Chem1998，41，24：	1
12	In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha- cyanoenol metabolite A77 1726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes显示文摘	Kalgutkar AS Nguyen HT Vaz AD	2003	Drug Metab Dispos2003，31，10：	1
13	A bioactivation pathways of organic functional groups显示文摘	Kalgutkar AS comprehensive Gardner I listing of Obach RS	2005	Curr Drug Metab2005，6，3：	1
14	Minimising the potential for metabolic activation in drug discovery 显示文摘	Kalgutkar AS Soglia JR	2005	Expert Opin Drug Metab Toxicol2005，1，1：	1
15	Mechanism-based inactivation of cytochrome P450 enzymes: chemical mechanisms, structure-activity relationships and relationship to clinical drug-drug interactions and idiosyncratic adverse drug reactions 显示文摘	Kalgutkar AS Obach RS Maurer TS	2007	Curr Drug Metab2007，8，：	1
16	A comprehensive listing of bioactivation pathways of organic functional groups显示文摘	Kalgutkar AS Gardner I Obach RS	2005	Curr Drug Metab2005，6，：	1
17	Minimizing the potential for metabolic activation in drug discovery显示文摘	Kalgutkar AS Soglia JR	2005	Expert Opin Drug Metab Toxicol2005，，：	1
18	Mechanism-based inactivation of human recombinant P450 2C9 by the nonsteroidal anti-inflammatory drug suprofen 显示文摘	O'Donnell JP Dalvie DK Kalgutkar AS	2003	Drug Metab Dispos2003，31，11：	1
19	Ester and amide derivatives of the nonsteroidal anti - inflammatory drug,indomethacin,as selective cyclooxygenase - 2 inhibitors显示文摘	Kalgutkar AS Marrnet AB Craws BC	2000	J Med Chem2000，43，15：	1
20	Aspirin like molecules that covalently inactivate cyclooxygenase -2显示文摘	Kalgutkar AS Crews BC Rowlinson SW	1998	Science1998，280，5367：	1

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