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56篇 您的检索式:作者名="Kalgutkar"
    题名 作者 年代 出处 被引量
1Indolyl Esters and Amides Related to Indomethacin are Selective COx-2 Inhibitors显示文摘Kalgutkar A S Crews C B Saleh S 2005Bioorg Med Chem Lett2005,13,24:1
2Drug metabolites as cytochrome p450 inhibitors: a retrospective analysis and proposed algorithm for evaluation of the pharmacokinetic interaction potential of metabolites in drug discovery and development 显示文摘Callegari E Kalgutkar AS Leung L 2013Drug Metab Dispos2013,41,12:1
3Preclinical species and human disposition of PF-04971729, a selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus 显示文摘Kalgutkar A S Tugnait M Zhu T 2011Drug Metab Dispos2011,39,9:1
4Aspirin-like molecules that covalently inactivate cyclooxygenase-2显示文摘Kalgutkar AS Crews BC Rowlinson SW 1998Science1998,280,5367:1
5Metabolic activation in drug-induced liver injury显示文摘Leung L Kalgutkar AS Obach RS 2012Drug Metab Rev2012,44,1:1
6Covalent modification of cyclooxygenase-2 (COX- 2) by 2-acetoxyphenyl alkyl sulfides, a new class of se- lective COX-Z inactivators 显示文摘(a) KALGUTKAR A S KOZAK K R CREWS B C 1998J Med Chem1998,41,24:1
7Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inbibitors显示文摘Kalgutkar AS Crews BC Rowlinson SW 2000Proc Natl Acad Sci USA2000,97,3:1
8Inhibition of hepatobiliary transport as a predictive method for clinical hepato- toxicity of nefazodone 显示文摘Kostrubsky S E Strom S C Kalgutkar A S 2006Toxicol Sci2006,90,2:1
9Ester and amidederivatives of the nonsteroidal anti-inflammatory drug,indomethacin, as selective cyclooxygenase-2 inhibitors显示文摘Kalgutkar AS Marnett AB Crews BC 2000J Med Chem2000,43,2:1
10Inhibition of hepatobiliary transport as a predictive method for clinical hepatotoxicity of nefazodone显示文摘Kostrubsky S E Strom S C Kalgutkar A S 2006Toxicol Sci2006,90,2:1
11Blastopathies symmetrical conjoined twins 显示文摘Kalgutkar AD Pethe V Pandit SP 1996Indian J Pathol Microbiol1996,39,3:1
12Covalent modification of cyclooxygen- ase-2 (COX-2) by 2-acetoxyphenyl alkyl sulfides, a new class of selective COX-2 inactivators 显示文摘Amit S Kalgutkar 1998J Med Chem1998,41,:1
13Ester and amide derivatires of the nonsteroidal anti-inflammatory drug, indomethacin as selective cyclooxygenase-2 inhibitors 显示文摘KALGUTKAR A MAMETT A B CROWS B 2000J Med Chem2000,43,15:1
14Aspirin - like molecules that covalendy inactivate cyclooxygenase - 2 显示文摘Kalgutkar AS Crews BC Rowlinson SW 1998Science1998,280,5367:1
15Biotransfor?mation reactions of five-membered aromatic heterocyclic rings显示文摘Dalvie DK Kalgutkar AS Khojasteh-Bakht SC 2002Chem Res Toxicol2002,15,3:1
16Biochemically based design of eyclooxygenase-2(COX-2) inhibitors : facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors显示文摘Kalgutkar AS Caews BC Rowlinson SW 2000Proc Natl Acad Sci USA2000,97,92:1
17Ester and amide derivatives of the nonsteroidal anti inflammatory drug,indomethacin,as selective cyclooxygenase-2 inhibitors显示文摘Kalgutkar AS Marrnet AB Craws BC 2000J Med Chem2000,43,15:1
18Interactions of nitrogen-containing xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR Studies on MAO substrates and inhibitors 显示文摘Kalgutkar A S Dalvie D K Jr N C 2001Chemical Research in Toxicology2001,9,14:1
19Aspirin-like molecules that covalently inactivate cyclooxygenase-2显示文摘Kalgutkar AS Crews BC Rowlinson SW 1998Science1998,280,12:1
20Covalent modification of cyclooxygenase-2(COX-2) by 2-acetoxyphenyl alkyl sulfides,a new class of selective COX-2 inactivators显示文摘 Kozak KR Crews BC 1998J Med Chem1998,41,24:1
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