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17篇 您的检索式:作者名="Kalb RG"
    题名 作者 年代 出处 被引量
1A PDZ protein regulates the distribution of the transmembrane semaphorin,M-SemF显示文摘Wang LH Kalb RG Strittmatter SM 1999J Biol Chem1999,274,14:1
2Serum/glueoeortieoid - inducible kinase can phosphorylate the cyclieAMP response element binding protein,CREB 显示文摘David S Kalb RG 2005FEBS Lett2005,579,6:1
3Sequence-specific cleavage of Huntingtin mRNA by catalytic DNA显示文摘Yen L Strittmatter SM Kalb RG 0,,:1
4Sequence-specific cleavage of Huntingtin mBNA by catalytic DNA 显示文摘Yen L Strittmatter SM Kalb RG 1999Ann Neurul1999,46,3:1
5A PDZ protein regulates the distribution of the transmembrane semaphorin, M- SemF显示文摘Wang LH Kalb RG Strittmatter SM 1999J Biol Chem1999,274,14:1
6Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway显示文摘Papapetropoulos A Fulton D Mahboubi K Kalb RG O'Connor DS Li F 2000J Biol Chem2000,275,13:1
7Molecular basis of semaphorin-mediated axon guidance显示文摘Nakamura F Kalb RG Strittmatter SM 2000J Neurobiol2000,44,2:1
8Expression of neural proteoglycans correlates with the acquisition of mature neuronal properties in the mammalian brain显示文摘Hockfield S Kalb RG Zaremba S 1990Cold Spring Harbor Syrup Quant Biol1990,55,14:1
9Angiopoietin-1 inhibitin-l inhibits endothelial cell apoptosis via the Akt/survivin pathway显示文摘Papatetropoulos A Fulton D Mahboubi K Kalb RG Oconnor DS Li F 2000J Biol Chem2000,275,13:1
10Sequence-specific cleavage of Huntington mRNA by catalytic DNA显示文摘 Strittmatter SM Kalb RG 1999Ann Neurol1999,46,3:1
11Molecular evidence for nitric oxide-mediated motor neuron development显示文摘Kalb RG Agostini J 0,,:1
12Sequence-specific cleavage of Huntington mRNA by catalytic DNA显示文摘 Strittmatter SM Kalb RG 1999Ann Neurol1999,46,3:1
13Getting the spinal cord to think for itself显示文摘Kalb RG 2003Arch Neurol2003,60,6:1
14GluAl promotes the activity-depen- dent development of motor circuitry in the developing segmen- tal spinal cord显示文摘Jablonski AM Kalb RG 2013AnnNYAcad Sci2013,1279,:1
15Sequence-specific Cleavage of Huntingtin mRNA by Catalytic DNA显示文摘 Strittmatter SM Kalb RG 1999Ann Neurol1999,46,3:1
16Sequence-specific cleavage of Huntingon mRNA by catalytic DNA 显示文摘Yen L Strittmatter SM Kalb RG 1999Ann Neurol1999,46,3:1
17No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors显示文摘Background:IgG-class autoantibodies to N-Methyl-D-Aspartate(NMDA)-type glutamate receptors define a novel entity of autoimmune encephalitis.Studies examining the prevalence of NMDA IgA/IgM antibodies in patients with Parkinson disease with/without dementia produced conflicting results.We measured NMDA antibodies in a large,well phenotyped sample of Parkinson patients without and with cognitive impairment(n=296)and controls(n=295)free of neuropsychiatric disease.Detailed phenotyping and large numbers allowed statistically meaningful correlation of antibody status with diagnostic subgroups as well as quantitative indicators of disease severity and cognitive impairment.Methods:NMDA antibodies were analysed in the serum of patients and controls using well established validated assays.We used anti-NMDA antibody positivity as the main independent variable and correlated it with disease status and phenotypic characteristics.Results:The frequency of NMDA IgA/IgM antibodies was lower in Parkinson patients(13%)than in controls(22%)and higher than in previous studies in both groups.NMDA IgA/IgM antibodies were neither significantly associated with diagnostic subclasses of Parkinson disease according to cognitive impairment,nor with quantitative indicators of disease severity and cognitive impairment.A positive NMDA antibody status was positively correlated with age in controls but not in Parkinson patients.Conclusion:It is unlikely albeit not impossible that NMDA antibodies play a significant role in the pathogenesis or progression of Parkinson disease e.g.to Parkinson disease with dementia,while NMDA IgG antibodies define a separate disease of its own.Franziska Hopfner Stefanie HMüller Dagmar Steppat Joanna Miller Nele Schmidt Klaus-Peter Wandinger Frank Leypoldt Daniela Berg Andre Franke Wolfgang Lieb Lukas Tittmann Monika Balzer-Geldsetzer Simon Baudrexel Richard Dodel Ruediger Hilker-Roggendorf Elke Kalbe Jan Kassubek Thomas Klockgether Inga Liepelt-Scarfone Brit Mollenhauer Petra Neuser Kathrin Reetz Oliver Riedel Claudia Schulte Jörg BSchulz Annika Spottke Alexander Storch Claudia Trenkwalder Hans-Ulrich Wittchen Karsten Witt Ullrich Wüllner Günther Deuschl Gregor Kuhlenbäumer 2019Translational Neurodegeneration2019,8,1:0
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