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| 1 | Prevalence of respiratory syncytial virus infection among children hospitalized with acute lower respiratory tract infections in Southern India显示文摘BACKGROUND Respiratory syncytial virus(RSV) is a leading cause of lower respiratory infections among children.AIM To investigate the proportion of RSV and non-RSV respiratory viral infections among hospitalized children ≤ 5 years.METHODS Hospitalized children aged < 5 years, with a diagnosis of acute lower respiratory infections(ALRI), admitted between August 2011-August 2013, were included.Cases were defined as laboratory-confirmed RSV and non-RSV respiratory viruses by direct fluorescence assay from the nasopharyngeal wash.RESULTS Of 383 1-59 mo old children hospitalized with an acute lower respiratory infection, 33.9%(130/383) had evidence of viral infection, and RSV was detected in 24.5%(94/383). Co-infections with RSV and other respiratory viruses(influenza A or B, adenovirus, para influenza 1, 2 or 3) were seen in children 5.5%(21/383). Over 90% of the RSV-positive children were under 2 years of age. RSV was detected throughout the year with peaks seen after the monsoon season.Children hospitalized with RSV infection were more likely to have been exposed to a shorter duration of breastfeeding of less than 3 mo. RSV positive children had a shorter hospital stay, although there were significant complications requiring intensive care. Use of antibiotics was high among those with RSV and non-RSV viral infections.CONCLUSION Our study provides evidence of a high proportion of RSV and other virusassociated ALRI among hospitalized children in India. RSV infection was associated with fewer days of hospital stay compared to other causes of lower respiratory infections. A high level of antibiotic use was seen among all respiratory virus-associated hospitalizations. These results suggest the need for implementing routine diagnostics for respiratory pathogens in order to minimize the use of unnecessary antibiotics and plan prevention strategies among pediatric populations. | Sandesh Kini Bhuvanesh Sukhlal Kalal Sara Chandy Ranjani Shamsundar Anita Shet | 2019 | World Journal of Clinical Pediatrics2019，8，2： | 3 |
| 2 | Effect of osteoporosis and intervertebral disc degeneration on endplate cartilage injury in rats显示文摘Objective:To investigate the effect of osteoporosis and intervertebral disc degeneration on the endplate cartilage injury in rats.Methods:A total of 48 female Sprague Dawley rats(3 months)were randomly divided into Groups A,B,C and D with 12 rats in each group.Osteoporosis and intervertebral disc degeneration composite model,simple degeneration model and simple osteoporosis model were prepared in Groups A,B and C respectively.After modeling,four rats of each group at 12th.18th and 24th week were sacrificed,Intervertebral height of cervical vertebra C6/C7 was measured.Micro-CT was used to image the endplate of cephalic and caudal cartilage at C6/C7 intervertebral disc.Abraded area rate of C6 caudal and C7 cephalic cartilage endplate was calculated,and then C6/C7 intervertebral disc was routinely embedded and sectioned.stained with safranin O to observe histological changes microscopically.Results:At 12,18 and24 weeks,intervertebral disc height of C6/C7 were(0.58±0.09)mm,(0.53±0.04)mm and(0.04±0.06)mm in Group A rats,(0.55±0.05)mm,(0.52±0.07)mm and(0.07±0.05)mm in Group B rats.At 24th week.intervertebral disc height of Group A rats was significantly lower than that of Group B rats(P<0.05);intervertebral disc height of Groups A and B rats at each time point were significantly lower than that of Groups C and D(P<0.05).There was no significantly statistical difference of intervertebral disc height between Groups C and D(P>0.05).At 12 and 18 weeks,the abraded rate of C6 caudal and C7 cephalic cartilage endplate in Group A rats were significantly higher than that in Groups B.C and D rats(P<0.05);the abraded rate in Group B was significantly higher than that in Groups C and D(P>0.05).Microscopic observation of CT showed that ventral defects in C6caudal or C7 cephalic cartilage endplate in Groups A and B appeared after 12 weeks of modeling;obvious cracks were found in front of the C6 and C7 vertebral body,and cartilage defect shown the trend of'repairing'at 18 and 24 weeks after modeling.Conclusions:Intervertebral disc degeneration and osteoporosis can cause damage to the cartilage endplate.Co-existence of these two factors can induce more serious damage to the endplate.which has possitive correlation with intervertebral disc degeneration.Osteoporosis plays a certain role in intervertebral disc degeneration process,and accelerates the degeneration of intervertebral disc in a specific time window. | Lei Wang Wei Cui Jean Pierre Kalal Tom Van Hoof Bao-Ge Liu | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，10： | 2 |
| 3 | Tracking Learning Detection 显示文摘 | Kalal Z Mikolajczyk K Matas J | 2011 | IEEE Transactions on Pattern Analysis and Machine Intelligence(S0162-8828)2011，6，1： | 1 |
| 4 | Thermal smoothing by laser-produced plasma of porous matter显示文摘 | KALAL M LIMPOUCH J KROUSKY E | 2003 | Fusion Science and Tech- nology2003，43，3： | 1 |
| 5 | Tracking-leaming-detection显示文摘 | Kalal Z Mikolajczyk K Matas J | 2012 | IEEE Transactions on Pattern Analysis and MachineIntelligence2012，34，7： | 1 |
| 6 | Tracking-learning-detection显示文摘 | Kalal Z Mikolajczyk K Matas J | 2012 | IEEE Transactions on Pattern Analysis and Machine Intel ligence2012，34，7： | 1 |
| 7 | Pn learning:Bootstrapping binary classifiers by structural constraints显示文摘 | Kalal Z Matas J Mikolajczyk K | | 0，，： | 1 |
| 8 | Tracking learning detection 显示文摘 | Kalal Z Mikolajczyk K Matas J | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 9 | Tracking-learning-detection 显示文摘 | Kalal Z Mikolajczyk K Matas J | 2012 | IEEE Trans on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 10 | Tracking-learning-detection 显示文摘 | KALAL Z MIKOLAJCZYK K MATAS J | 2012 | Pattern Analysis and Machine In-telligence IEEE Transactions on2012，34，7： | 1 |
| 11 | Tracking-learning-detec- tion显示文摘 | Kalal Z Mikolajczyk K Matas J | 2010 | IEEE Transactions on Pattern Analysis and Ma- chine Intelligence2010，6，1： | 1 |
| 12 | Tracking- learning-detection显示文摘 | Kalal Z Mikolajczyk K and Matas J | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 13 | Tracking learning detection显示文摘 | KALAL Z MIKOLAJCZYK K MATAS J | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 14 | Tracking learning detection显示文摘 | KALAL Z MIKOLAJCZYK K and MATAS J | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 15 | Tracking-learning-detection显示文摘 | Kalal Z Mikolajczyk K Matas J | | 0，，07： | 1 |
| 16 | Tracking-learning-de-tection 显示文摘 | Kalal Z Mikolaiczyk K Matas J | 2012 | Pattern Analysis and Machine Intelligence IEEE Transactions on2012，34，7： | 1 |
| 17 | Tracking- Learning-detection显示文摘 | KALAL Z MIKOLAJCZYK K MATAS J | 2011 | IEEE Transactions on Pattern Analysis and Machine Intelligence2011，34，7： | 1 |
| 18 | Tracking-learuing- detection显示文摘 | Kalal Z Mikolajczyk K Matas J | 2012 | IEEE Transactions on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 19 | Tracking-learning-detection显示文摘 | Kalal Z Mikolajczyk K Matas J | 2012 | IEEE Trans on Pattern Analysis and Machine Intelligence2012，34，7： | 1 |
| 20 | Tracking learning detection 显示文摘 | KALAL Z MIKOLAJCZYK K MATAS J | 2011 | IEEE transactions on pattern analysis & machine intelligence2011，34，7： | 1 |
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