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| 1 | 左心室舒张功能的遗传性和其他影响因素:以家庭为基础的人口研究显示文摘确定遗传因素影响舒张功能多普勒指数的程度,是评估左心室舒张功能障碍与预后关系的一个重要因素。因此,研究人员从一般人群中选出家庭样本,对其家族左心室舒张特性和舒张功能集合评分的遗传度进行评估。方法:随机抽取316个家庭样本,包括452名父母和600名后代,平均年龄分别为58.5和33.3岁, | 刘莉 叶鹏 Kloch-Badelek M Knez J Tikhonoff V Thijs L Sakiewicz W Ryabikov A Stolarz-Skrzypek K Jin Y Malyutina S Casiglia E Narkiewicz K Czarnecka D Kawecka-Jaszcz K Staessen JA Kuznetsova T | 2014 | 中华高血压杂志2014，22，10： | 2 |
| 2 | Field trials of viral preparation viroden on preimaginal stages of blood sucking mosquitoes 显示文摘 | Buchatsky L P Bogdanova E N Kuznetsova M A | 1987 | Med Parasitol Bolezni1987，4，： | 1 |
| 3 | Shockwave activation of high-temperature ferroelectric powders显示文摘 | KUZNETSOVA E M REZNICHENKO L A RAZUMOVSKAYA O N | 2000 | Tech Phys Lett2000，26，9： | 1 |
| 4 | 查看详情显示文摘 | Kuznetsova T G Sadykov V A Moroz E M Trukhan S N Paukshtis E A Kolomiichuk V N Burgina E B Zaikovskii V I Fedotov M A Lunin V V Kemnitz E | | 0，，： | 1 |
| 5 | Methane transformation into syngas over Ce-Zr-O systems:role of the surface/bulk promoters and oxygen mobility显示文摘 | Kuznetsova T G Sadykov V A Veniaminov S A Alikina G M Moroz E M Rogov V A Martyanov O N Yudanov V F Abornev I S Neophytides S | | 0，，： | 1 |
| 6 | Genome- wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family 显示文摘 | Kuznetsova E Proudfoot M Gonzalez C F | 2006 | Journal of Biological Chemistry2006，281，36： | 1 |
| 7 | Low-molecular-weight, biologically active compounds from marine Pseudoaheromonas species显示文摘 | Kalinovskaya N I Ivanova E P Alexeeva Y V Gorshkova N M Kuznetsova T A Dmitrenok A S Nicolau D V | 2004 | Current Microbiology2004，48，： | 1 |
| 8 | Enzyme genomics:application of general enzymatic screens to discover new enzymes 显示文摘 | Kuznetsova E Proudfoot M Sanders SA et ol | 2005 | FEMS Microbiol2005，29，： | 1 |
| 9 | Investigation of temporal-spatial parameters of an urban heat island on the basis of passive microwave remote sensing 显示文摘 | Khaikine M N Kuznetsova I N Kadygrov E N | 2006 | Theoretical and Applied Climatology2006，84，13： | 1 |
| 10 | Shockwave Activation of High-Temperature Ferroelectric Powders显示文摘 | Kuznetsova E M Reznichenko L A Razumovskaya O N | 2000 | Technical Physics Letters2000，26，9： | 1 |
| 11 | Genome- wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family显示文摘 | Kuznetsova E Proudfoot M Gonzalez C F | 2006 | J Biol Chem2006，281，36： | 1 |
| 12 | Flavoprotein miniSOG as a genetically encoded photosensitizer for cancer cells显示文摘 | Ryumina A P Serebrovskaya E O Shirmanova M V Snopova L B Kuznetsova M M Turchin I V Ignatova N I Klementieva N V Fradkov A F Shakhov B E Zagaynova E V Lukyanov K A Lukyanov S A | 2013 | Biochim Biophys Acta2013，1830，11： | 1 |
| 13 | Correlation of p16/INK4a gene damages and protein expression in the tumor tissue of sporadic breast cancer显示文摘 | Nemtsova M V Zemliakova V V Kuznetsova E V | 2008 | Arkh Patol2008，70，4： | 1 |
| 14 | Shockwave activation of high-temperature ferroe- lectric powders显示文摘 | Kuznetsova E M Reznichenko L A Razumovskaya O N | 2000 | Technical Physics Letters2000，26，9： | 1 |
| 15 | 查看详情显示文摘 | Sadykov V A Kuznetsova T G Alikina G M Frolova Y V Lukashevich A I Potapova Y V Muzykantov V S Rogov V A Kriventsov V V Kochubei D I Moroz E M Zyuzin D A Zaikovskii V I Kolomiichuk V N Paukshtis E A Burgina E B Zyryanov V V Uvarov N F Neophytides S Kemnit | | 0，，： | 1 |
| 16 | Systemic juvenile idiopathic arthritis–associated lung disease: A retrospective cohort study显示文摘BACKGROUND Lung damage in systemic juvenile arthritis(sJIA)is one of the contemporary topics in pediatric rheumatology.Several previous studies showed the severe course and fatal outcomes in some patients.The information about interstitial lung disease(ILD)in the sJIA is scarce and limited to a total of 100 cases.AIM To describe the features of sJIA patients with ILD in detail.METHODS In the present retrospective cohort study,information about 5 patients less than 18-years-old with sJIA and ILD were included.The diagnosis of sJIA was made according to the current 2004 and new provisional International League of Associations for Rheumatology criteria 2019.ILD was diagnosed with chest computed tomography with the exclusion of other possible reasons for concurrent lung involvement.Macrophage activation syndrome(MAS)was diagnosed with HLH-2004 and 2016 EULAR/ACR/PRINTO Classification Criteria and hScores were calculated during the lung involvement.RESULTS The onset age of sJIA ranged from 1 year to 10 years.The time interval before ILD ranged from 1 mo to 3 years.The disease course was characterized by the prevalence of the systemic features above articular involvement,intensive rash(100%),persistent and very active MAS(hScore range:194-220)with transaminitis(100%),and respiratory symptoms(100%).Only 3 patients(60%)developed a clubbing phenomenon.All patients(100%)had pleural effusion and 4 patients(80%)had pericardial effusion at the disease onset.Two patients(40%)developed pulmonary arterial hypertension.Infusion-related reactions to tocilizumab were observed in 3(60%)of the patients.One patient with trisomy 21 had a fatal disease course.Half of the remaining patients had sJIA remission and 2 patients had improvement.Lung disease improved in 3 patients(75%),but 1 of them had initial deterioration of lung involvement.One patient who has not achieved the sJIA remission had the progressed course of ILD.No cases of hyper-eosinophilia were noted.Four patients(80%)received canakinumab and one(20%)tocilizumab at the last follow-up visit.CONCLUSION ILD is a severe life-threatening complication of sJIA that may affect children of different ages with different time intervals since the disease onset.Extensive rash,serositis(especially pleuritis),full-blown MAS with transaminitis,lymphopenia,trisomy 21,eosinophilia,and biologic infusion reaction are the main predictors of ILD.The following studies are needed to find the predictors,pathogenesis,and treatment options,for preventing and treating the ILD in sJIA patients. | Konstantin E Belozerov Natalia M Solomatina Eugenia A Isupova Alla A Kuznetsova Mikhail M Kostik | 2024 | World Journal of Clinical Pediatrics2024，13，1： | 0 |
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