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| 1 | Speech and language therapy for aphasia following subacute stroke显示文摘The aim of this study was to investigate the time window, duration and intensity of optimal speech and language therapy applied to aphasic patients with subacute stroke in our hospital. The study consisted of 33 patients being hospitalized for stroke rehabilitation in our hospital with first stroke but without previous history of speech and language therapy. Sixteen sessions of impairment-based speech and language therapy were applied to the patients, 30–60 minutes per day, 2 days a week, for 8 successive weeks. Aphasia assessment in stroke patients was performed with Gülhane Aphasia Test-2 before and after treatment. Compared with before treatment, fluency of speech, listening comprehension, reading comprehension, oral motor evaluation, automatic speech, repetition and naming were improved after treatment. This suggests that 16 seesions of speech and language therapy, 30–60 minutes per day, 2 days a week, for 8 successive weeks, are effective in the treatment of aphasic patients with subacute stroke. | Engin Koyuncu Pinar Cam Nermin Altinok Duygu Ekinci Calli Tuba Yarbay Duman Nese Ozgirgin | 2016 | Neural Regeneration Research2016，11，10： | 9 |
| 2 | Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis显示文摘AIM:To investigate in vitro effects of propofol,midazolam and dexmedetomidine,which are commonly used anaesthesic or sedatives,on spontaneous contractions of the ileum both in normal rats and those exposed to hyperdynamic peritonitis.METHODS:Spontaneous contractions of isolated ileum muscle segments from sham operated rats and those exposed to peritonitis,were studied in vitro.The amplitude and the frequency of spontaneous contractions of ileum muscle segments were studied after adding dexmetetomidine,propofol,and midazolam to the organ bath in a cumulative manner.RESULTS:Both amplitude(85.2±6.6 vs 47.4±7.1)and frequency(32.8±4.6 vs 20.2±3.9)of spontaneous contractions in ileum smooth muscle segments were decreased significantly in the peritonitis group compared to the control group(P<0.05).Dexmedetomidine significantly increased the amplitude of spontaneous contractions(85.2±6.6 vs 152.0±5.4,P<0.05)whereas,propofol(85.2±6.6 vs 49.6±4.8,P<0.05)and midazolam(85.2±6.6 vs 39.2±4.5,P<0.05)decreased it in both control and peritonitis groups.The frequency of spontaneous contractions were significantly decreased by propofol in both control(32.8±4.6 vs 18.2±3.4,P<0.05)and peritonitis groups 20.2±3.9 vs 11.6±3.2,P<0.05).Dexmedetomidine and midazolam did not cause significant changes in the number of spontaneous contractions in both control and the peritonitis groups(P>0.05).CONCLUSION:Propofol,midazolam and dexmedetomidine have various in vitro effects on spontaneous contractions of the rat ileum.While dexmedetomidine augments the spontaneous contraction of the rat ileum,propofol attenuates it.However,the effects of these compounds were parallel in both control and peritonitis groups. | Cengiz Aydin Ihsan Bagcivan Sinan Gursoy Ahmet Altun Omer Topcu Ayhan Koyuncu | 2009 | World Journal of Gastroenterology2009，15，13： | 6 |
| 3 | Adsorption of Pb(II) ions from aqueous solution by native and activated bentonite: Kinetic, equilibrium and thermodynamic study显示文摘 | Ali R?za Kul Hülya Koyuncu | 2010 | Journal of Hazardous Materials2010，，1： | 2 |
| 4 | Cytotoxic, genotoxic and apoptotic effects of naringenin-oxime relative to naringenin on normal and cancer cell lines显示文摘Objective: To assess and compare the cytotoxic, genotoxic, apoptotic and reactive oxygen species(ROS) generating effects of naringenin(NG) and its new derived compound naringenin-oxime(NG-Ox) on MCF-7, HT-29, PC-12 cancer and L-929 normal cell lines.Methods: The cells were incubated with different doses of NG-Ox and NG(50–1 000 mmol/L) for 24 h. The cell viability was assessed based on ATP cell viability assay.Intracellular accumulation of ROS was determined using the fluorescent probes 2070-dichlorodihydrofluorescin diacetate. Genotoxic effects were evaluated by alkaline single cell gel electrophoresis assay(comet assay) and, the apoptotic effect was evaluated by acridine orange staining at below the IC50 levels.Results: Both NG-Ox and NG exhibited cytotoxic, genotoxic and apoptotic effects and resulted in increased ROS values in a dose-dependent manner. The effects were more pronounced on cancer cell lines. The cytotoxic, genotoxic and apoptotic effects of NG-Ox were higher than that of NG in all cell lines. Significant correlations were observed between cell viability, DNA damage, apoptosis and ROS, in all cell lines exposed to either NG-Ox or NG.Conclusions: This study showed that both NG-Ox and NG possess cytotoxic, genotoxic and apoptotic activities through the production of ROS on cells, NG-Ox being the more effective one. Therefore, derived compound of NG might be used as antiproliferative agents for the treatment of cancer. | Abdurrahim Kocyigit Ismail Koyuncu Murat Dikilitas Fatemeh Bahadori Baki Turkkan | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，10： | 2 |
| 5 | Dissociative disorders in a psychiatric emergency ward显示文摘 | Sar V Koyuncu A Ozturk E | 2007 | Cen Hosp Psychiatry2007，29，1： | 1 |
| 6 | The effectiveness of functional electrical stimulation for the treatment of shoulder subluxation and shoulder pain in hemiplegic patients:A randomized controlled trial显示文摘 | Koyuncu E Nakipo lu-Yüzer GF Do an A | | 0，，07： | 1 |
| 7 | Fat and fatty acid composition of hazelnut kernels in vacuum packages during storage显示文摘 | Koyuncu M A Islam A Ktiqtik M | 2005 | Grasas y Aceites2005，56，4： | 1 |
| 8 | Application of low pressure NF membme for the recovery and reuse of dairy in- dustry effluents显示文摘 | Koyuncu I Turan M Topacik D | 2000 | Water Sci Techn2000，41，1： | 1 |
| 9 | The effec- tiveness of functional electrical stimulation for the treatment of shoulder subluxation and shoulder pain in hemiplegic patients: A randomized controlled trial 显示文摘 | Koyuncu E Nakipolu-Yiizer GF Do an A | 2010 | Disabil Rehabil2010，32，7： | 1 |
| 10 | Desalination of produced water from oil production fields by membrane processes 显示文摘 | Mehmet Cakmakca Necati Kayaalp Isrnail Koyuncu | 2008 | Desalination2008，222，： | 1 |
| 11 | Tuberculosis of the pancreas 显示文摘 | Sozbilen M Erhan Y Koyuncu A | 1992 | Br J Surg1992，79，： | 1 |
| 12 | Antigenotoxic and antiox- idant potentials of newly derivatized compound naringenin-oxime relative to naringenin on human mononuclear cells显示文摘 | Kocyigit A Koyuncu I Taskin A | 2015 | Drug Chem Toxicol2015，31，1： | 1 |
| 13 | A survey of indoor positioning and object locating systems显示文摘 | Koyuncu H Yang S H | 2010 | IJCSNS International Journal of Computer Science and Network Security2010，10，5： | 1 |
| 14 | Direct trocar insertion versus Veress needle insertion in laparoscopic cholecystectomy显示文摘 | Yerdel MA Karayalcin K Koyuncu A | 1999 | Am J Surg1999，177，： | 1 |
| 15 | Serum resistin and insulin-like growth factor-1 levels in patients with hy- pothyroidism and hyperthyroidism显示文摘 | Eke Koyuncu C Turkmen Yildinrmak S Temizel M | 2013 | J''Thyroid Res2013，2013，30： | 1 |
| 16 | The cold storage of some persimmon fruit cultivars显示文摘 | Koyuncu M A Savran E Dilmacunal T Kepenek K Cangi R Cagatay O | | 0，，01： | 1 |
| 17 | Color removal of high strength paper- and fermentation industry effluents with membranet echnology 显示文摘 | Koyuncu I Yalcin F | 1999 | Water Science and Technology1999，40，1112： | 1 |
| 18 | Advanced physicochemical treatment experiences on young municipal landfill leachates 显示文摘 | Ozturki Ahinbas M Koyuncu I | 2003 | Waste Management2003，23，5： | 1 |
| 19 | Reactive dye removal in dye/ salt mixtures by nanofiltration membranes containing vinylsulphone dyes effects of feed concentration and cross folw velocity显示文摘 | Ismail Koyuncu | 2002 | Desalination2002，143，3： | 1 |
| 20 | Removal of hormones and antibiotics by nanofiltration membranes 显示文摘 | Koyuncu l Arikan O A Wiesner M R | 2008 | Journal of Membrane Science2008，309，： | 1 |
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