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	题名	作者	年代	出处	被引量
1	Integration of hepatitis B virus DNA into chromosomal DNA during acute hepatitis B显示文摘AIM: To examine the serum from black African patients with acute hepatitis B to ascertain if integrants of viral DNA can be detected in fragments of cellular DNA leaking from damaged hepatocytes into the circulation.METHODS: DNA was extracted from the sera of five patients with uncomplicated acute hepatitis B and one with fulminant disease. Two subgenomic PCRs designed to amplify the complete genome of HBV were used and the resulting amplicons were cloned and sequenced.RESULTS: HBV and chromosomal DNA were amplified from the sera of all the patients. In one patient with uncomplicated disease, HBV DNA was integrated into host chromosome 7 q11.23 in the WBSCR1 gene. The viral DNA comprised 200 nucleotides covering the S and X genes in opposite orientation, with a 1 169 nudeotide deletion. The right virus/host junction was situated at nucleotide 1774 in the cohesive overlap region of the viral genome, at a preferred topoisomerase I cleavage motif. The chromosomal DNA was not rearranged.The patient made a full recovery and seroconverted to anti-HBs- and anti-HBe-positivity. Neither HBV nor chromosomal DNA could be amplified from his serum at that time.CONCLUSION: Integration of viral DNA into chromosomal DNA may occur rarely during acute hepatitis B and, with clonal propagation of the integrant, might play a role in hepatocarcinogenesis.	Gerald C Kimbi Anna Kramvis Michael C Kew	2005	World Journal of Gastroenterology2005，11，41：	11
2	Induction of chloroquine resistance in P lasmodiumyoelii nigeriensis显示文摘	Kimbi HK Fagbenro Beyioku AF	1996	East Afr Med J1996，73，：	1
3	ESMO Guidelines consensus conference on malignant lymphoma 2011 part1:diffuse large B-cell lymphoma(DLBCL),follicular lymphoma(FL)and chronic lymphocytic leukemia(CLL)显示文摘	GHIELMINI M VITOLO U KIMBY E	2013	Ann Oncol2013，24，：	1
4	Long-term molecular remissions in patients with indolent lymphoma treated with rituximab as a single agent or in combination with interferon alpha-2a: A randomized phase Ⅱ study from the Nordic Lymphoma Group显示文摘	Kimby E Jurlander J Geisler C	2008	Leuk Lymphoma2008，49，1：	1
5	Smallholder Pigs Production Systems in Tanzania显示文摘	Eliakunda Kimbi Faustin Lekule James Mlangwa Helena Mejer Stig Thamsborg	2015	Journal of Agricultural Science and Technology(A)2015，5，1：	1
6	Portal vein thrombosis is a common complication following splenectomy in patients with malignant haematological diseases显示文摘	Svensson M Wiren M Kimby E	2006	Eur J Haematol2006，77，3：	1
7	A systematic overview of chemotherapy effects in acute myeloid leukaemia 显示文摘	Kimby E Nygren P Glimelius B	2001	Acta Oncol2001，40，23：	1
8	A systematic overview of chemotherapy effects in aggressive non- Hodgkin's lymphoma显示文摘	Kimby E Brandt L Nygren P	2001	Acta Oncol2001，40，23：	1
9	A systematic overview of chemotherapy effects in acute myeloid leukaemia显示文摘	Kimby E Nygren P Glimelius B	2001	Acta Oncol2001，40，23：	1
10	Phase 1I trial of subcutaneous anti - CD52monoclonal antibody alemtuzumab (CAMPATH- IH)as lust-line treatment for patients with B- cell chronic lymphocytic leukemia(B - CLL) 显示文摘	Lundin J Kimby E Bjorkbolm M	2002	Blood2002，100，：	1
11	Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: the EB- MT transplant consensus显示文摘	Dreger P Corradini P Kimby E	2007	Leukemia2007，21，1：	1
12	A systematic overview of chemotherapy effects in acute myeloid leukaemia显示文摘	Kimby E Nygren P Glimelius B	2001	Acta Oncol2001，40，：	1
13	A systematic overview of chemotherapy effects in aggressive non-Hodgkin's lymphoma显示文摘	Kimby E Brandt L Nygren P	2001	Acta Oncol2001，40，23：	1
14	A systematic overview of chemotherapy effects in acute myeloid leukemia显示文摘	Kimby E Nygren P Glimellus B	2001	Acta Oncol2001，40，2：	1
15	Update on recommendations for assessing response from the Third International Workshop on Waldenstroms Macroglobulinemia显示文摘	Kimby E Treon SP Anagnostopoulos A	2006	Clin Lymphoma Myeloma2006，6，5：	1
16	Phase Ⅱ trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)显示文摘	KIMBY E BJORKHOLM M	2002	Blood2002，100，：	1
17	Phase Ⅱ trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath- 1 H)as first-line treatment for patients with B-cell chronic lymphoeytic leukemia (B-CLL) 显示文摘	Lundin J Kimby E Bj rkholm M	2002	Blood2002，100，3：	1
18	Phase Ⅱ trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-lH) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL) 显示文摘	LUNDIN J KIMBY E BJORKHOLM M	2002	Blood2002，100，3：	1
19	Propagation and optical interaction of guided acoustic waves in two-mode optical fibers显示文摘	ENGAN H E KIMBY BLACKJ N	1988	J Lightwave Technol1988，6，3：	1
20	A systematic overview of chemotherapy effects in acute myeloid leukaemia显示文摘	Kimby E Nygren P Glimelius B	2001	Acta Oncol2001，40，23：	1

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