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    题名 作者 年代 出处 被引量
1Salvia miltiorrhiza: Traditional medicinal uses, chemistry, and pharmacology显示文摘Salvia miltiorrhiza Bunge(SM) is a very popular medicinal plant that has been extensively applied for many years to treat various diseases, especially coronary heart diseases and cerebrovascular diseases, either alone or in combination with other Chinese plant-based medicines. Although a large number of studies on SM have been performed, they are scattered across a variety of publications. The present review is an up-to-date summary of the published scientific information about the traditional uses, chemical constituents, pharmacological effects, side effects, and drug interactions with SM, in order to lay the foundation for further investigations and better utilization of SM. SM contains diverse chemical components including diterpenoid quinones, hydrophilic phenolic acids, and essential oils. Many pharmacological studies have been done on SM during the last 30 years, focusing on the cardiovascular and cerebrovascular effects, and the antioxidative, neuroprotective, antifibrotic, anti-inflammatory, and antineoplastic activities. The research results strongly support the notion that SM has beneficial therapeutic properties and has a potential of being an effective adaptogenic remedy.SU Chun-Yan MING Qian-Liang RAHMAN Khalid HAN Ting QIN Lu-Ping 2015Chinese Journal of Natural Medicines2015,13,3:74
2苍耳子中酚酸类化合物及不同品种和居群苍耳子中总酚酸含量的测定(英文)显示文摘目的:研究中药苍耳子(FructusXanthii)中的化学成分;测定不同居群和不同品种苍耳属植物果实中的总酚酸含量以评价其品质。方法:运用各种层析方法分离纯化化合物,以绿原酸作对照,用紫外分光光度法测定总酚酸的含量。结果:(1)从苍耳子中分离到6个咖啡酰奎宁酸类化合物,以及咖啡酸和阿魏酸;(2)从中国29个居群采集到的样品,总酚酸含量为0.31%~1.44%。在采集到2个品种及1个变种的苍耳属植物中,近无刺苍耳X.sibiricumvar.subinerme样品的总酚酸含量较其他两种都偏低。苍耳X.sibiricum样品中,从上海采集的3号苍耳子样品总酚酸含量最高,达1.44%,而从江西新建采集的12号样品含量最低,仅0.38%。结论:5O咖啡酰奎宁酸,1,4-二O咖啡酰奎宁酸和4,5二O咖啡酰奎宁酸是从苍耳属植物中首次分离获得。不同品种和不同居群苍耳子药材中,总酚酸含量的差异较为显著。若以总酚酸含量作为指标评价苍耳子药材的品质,则认为上海和福建三明产苍耳子为优质种群。韩婷 李慧梁 胡园 张巧艳 黄宝康 郑汉臣 Khalid RAHMAN 秦路平 2006中西医结合学报2006,4,2:45
3Epidemiology of varicocele显示文摘精索静脉曲张是在繁殖的药实践的一个普通问题。精索静脉曲张与主要不孕在 15% 健康的人被识别。精索静脉曲张的准确 pathophysiology 很好没被理解,特别关于它男不孕上的效果。我们进行了在一般人口并且在与不孕介绍的人评估精索静脉曲张的传染病学的研究的系统的评论。在这篇文章,我们识别了一些能影响精索静脉曲张的流行病学的方面的因素。我们也认识到精索静脉曲张传染病学仍然保持不完全地理解,并且有需要让设计得好的、大规模研究充分定义这个条件的流行病学的方面。Bader Alsaikhan Khalid Alrabeeah Guila Delouya Armand Zini 2016Asian Journal of Andrology2016,18,2:44
4Type 2 diabetes mellitus:From a metabolic disorder to an inflammatory condition显示文摘Diabetes mellitus is increasing at an alarming rate and has become a global challenge.Insulin resistance intarget tissues and a relative deficiency of insulin secretion from pancreatic β-cells are the major features of type 2 diabetes(T2D).Chronic low-grade inflammation in T2 D has given an impetus to the field of immuno-metabolism linking inflammation to insulin resistance and β-cell dysfunction.Many factors advocate a causal link between metabolic stress and inflammation.Numerous cellular factors trigger inflammatory signalling cascades,and as a result T2 D is at the moment considered an inflammatory disorder triggered by disordered metabolism.Cellular mechanisms like activation of Tolllike receptors,Endoplasmic Reticulum stress,and inflammasome activation are related to the nutrient excess linking pathogenesis and progression of T2 D with inflammation.This paper aims to systematically review the metabolic profile and role of various inflammatory pathways in T2 D by capturing relevant evidence from various sources.The perspectives include suggestions for the development of therapies involving the shift from metabolic stress to homeostasis that would favour insulin sensitivity and survival of pancreatic β-cells in T2 D.Iqra Hameed Shariq R Masoodi Shahnaz A Mir Mudasar Nabi Khalid Ghazanfar Bashir A Ganai 2015World Journal of Diabetes2015,6,4:36
5A comparative review of HLA associations with hepatitis Band C viral infections across global populations显示文摘Hepatitis B (HBV) and hepatitis C (HCV) viral infection or co-infection leads to risk of development of chronic infection, cirrhosis and hepatocellular carcinoma (HCC). Immigration and globalization have added to the challenges of public health concerns regarding chronic HBV and HCV infections worldwide. The aim of this study is to review existing global literature across ethnic populations on HBV and HCV related human leukocyte antigen (HLA) associations in relation to susceptibility, viral persistence and treatment. Extensive literature search was conducted to explore the HLA associations in HBV and HCV infections reported across global populations over the past decade to understand the knowledge status, weaknesses and strengths of this information in different ethnic populations. HLA DR13 is consistently associated with HBV clearance globally. HLADRB1*11/*12 alleles and DQB1*0301 are associated with HBV persistence but with HCV clearance worldwide. Consistent association of DRB1*03 and *07 is observed with HCV susceptibility and non-responsiveness to HBV vaccination across the population. HLA DR13 is protective for vertical HBV and HCV transmission in Chinese and Italian neonates, but different alleles are associated with their susceptibility in these populations. HLA class Ⅰmolecule interactions with Killer cell immunoglobulin like receptors (KIR) of natural killer (NK) cells modulate HCV infection outcome via regulating immune regulatory cells and molecules. HLA associations with HBV vaccination, interferon therapy in HBV and HCV, and with extra hepatic manifestations of viral hepatitis are also discussed. Systematic studies in compliance with global regulatory standards are required to identify the HLA specific viral epitope, stage specific T cell populations interacting with different HLA alleles during disease progression and viral clearance of chronic HBV or HCV infections among different ethnic populations. These studies would facilitate stage specific therapeutic strategies for clearance of HBV and HCV infections or co-infections across global populations and aid in identification of HBV-HCV combined vaccine. HLA associations of chronic HBV or HCV development with confounding host factors including alcohol, drug abuse, insulin resistance, age and gender are lacking and warrant detailed investigation across global populations.Rashmi Singh Rashmi Kaul Anil Kaul Khalid Khan 2007World Journal of Gastroenterology2007,13,12:31
6基于波形相似度比较的线路快速纵联保护研究显示文摘针对基于工频量线路纵联保护动作速度受制于滤波算法数据窗以及抗干扰能力不足的问题,提出一种基于波形相似度比较的线路快速纵联保护算法。该方法利用故障发生后故障线路两侧波形间不一致形变的特征,通过Hausdorff距离算法对包括故障暂态时刻在内的任意时刻信号进行相似度比较,实现故障的快速识别和切除。该文结合算法特点提出对应的保护整定方法,并在整定的基础上分析算法的动作特性。针对原有Hausdorff距离算法受异常数据影响的缺陷,分析线路保护可能面临的异常数据特征,提出相应的改进策略。理论分析和仿真试验验证了所提算法的有效性和优越性。陈乐 薄志谦 林湘宁 魏繁荣 余梦琪 金能 Muhammad Shoaib Khalid 李正天 黄景光 邓科 2017中国电机工程学报2017,37,17:33
7考虑可转移负荷效率的风/光/柴/蓄孤岛微网日运行能量控制优化策略显示文摘大型负荷尤其是可转移负荷的效率–功率特性常常被忽视,因此考虑风/光/柴/蓄微网系统的运行调度是不经济的。该文提出一种考虑可转移负荷效率的风/光/柴/蓄微网能量控制优化策略。首先以典型的可转移负荷——反渗透型制淡设备为例,建立包含设备工作全程的淡水输入–产出模型,实时计算其功率–效率特性曲线。在考虑制淡设备功率特性、蓄电池寿命(使用成本)、柴油机工作效率等因素的基础上,以燃料及蓄电池使用成本最少为目标,提出一种风/光/柴/蓄微网系统的日运行能量控制优化策略。通过与两种典型微网能量控制方案进行比较,仿真结果验证在包含可转移负荷的微网场景中,针对各种可能的储能设备和燃料的使用成本组合,在淡水需求量一定时,所提策略均具有较好的成本优势,为包含可转移负荷的微网经济运行策略制定提供了全新的视角。魏繁荣 随权 林湘宁 李正天 陈乐 邓科 薄志谦 黄景光 Muhammad Shoaib Khalid Owolabi Sunday Adio 2018中国电机工程学报2018,38,4:34
8Hepatitis B virus,HBx mutants and their role in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC)is one of the leading causes of death induced by cancer in the modern world and majority of the cases are related to chronic hepatitis B virus(HBV)infection.HBV-encoded X protein(HBx)is known to play a pivotal role in the pathogenesis of viral induced HCC.HBx is a multifunctional protein of17 kDa which modulates several cellular processes by direct or indirect interaction with a repertoire of host factors resulting in HCC.HBX might interfere with several cellular processes such as oxidative stress,DNA repair,signal transduction,transcription,protein degradation,cell cycle progression and apoptosis.A number of reports have indicated that HBx is one of the most common viral ORFs that is often integrated into the host genome and its sequence variants play a crucial role in HCC.By mutational or deletion analysis it was shown that carboxy terminal of HBx has a likely role in protein-protein interactions,transcriptional transactivation,DNA repair,cell,signaling and pathogenesis of HCC.The accumulated evidence thus far suggests that it is difficult to understand the mechanistic nature of HBx associated HCC,and HBx mediated transcriptional transactivation and signaling pathways may be a major determinant.This article addresses the role of HBx in the development of HCC with particular emphasis on HBx mutants and their putative targets.Ashraf Ali Hany Abdel-Hafiz Mohd Suhail Amany Al-Mars Mohammad Khalid Zakaria Kaneez Fatima Sultan Ahmad Esam Azhar Adeel Chaudhary Ishtiaq Qadri 2014World Journal of Gastroenterology2014,20,30:29
9Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea显示文摘瞄准:估计酵母属 boulardii 的功效和安全(S。boulardii ) 在在减少腹泻的事件的频率在的尖锐水的腹泻和它的角色随后二个月。方法:从 2 瞬间的孩子到 12 岁,在 S 根据包括标准和随机的 ised 与尖锐腹泻被选择。boulardii 组(与 ORS,营养的支持和 S 一起对待。boulardii, 250 mg 出价) 并且在控制组(仅仅与 ORS 和营养的支持一起对待) 。直接疗法阶段是 5 d,每个孩子以后被跟随二个月。象药的安全一样的凳子的频率和一致性在每访问上被估计。二个组的比较以痢疾的事件的数字被做在随后二个月。结果:在每个组有五十个病人。象吝啬的年龄和凳子的平均频率那样的基线特征在 S 是可比较的。boulardii 和控制在试用在包括的时候组织。由 d 3 它分别地并且由 d 每 d 归结为 2.7 和 4.2 张凳子 6 它归结为 1.6 (S。boulardii 组) 并且 3.3 (控制组) 。腹泻的持续时间是在 S 的 3.6 d。而它是在控制组的 4.8 d, boulardii 组织(P = 0.001 ) 。在下列二个月内, S。有的 boulardii 组一显著地, 0.54 个事件的低频率作为与在控制的 1.08 个事件相比组织。这药很好被接受并且容忍。在治疗时期期间没有副作用的报告。结论:S。boulardii 显著地减少尖锐腹泻的频率和持续时间。凳子的一致性也改善。这药是容忍得好的。AG Billoo MA Memon SA Khaskheli G Murtaza Khalid Iqbal M Saeed Shekhani Ahson Q Siddiqi 2006World Journal of Gastroenterology2006,12,28:22
10紫花牡荆素体内抗炎作用的研究(英文)显示文摘目的:探讨中药蔓荆子中主要成分紫花牡荆素的抗炎作用。方法:通过急性抗炎模型——二甲苯致小鼠耳廓肿胀实验、鸡蛋清致大鼠足跖肿胀实验以及腹腔注射0.7%醋酸致小鼠腹腔毛细血管通透性增高的实验,观察紫花牡荆素的抗炎作用。结果:紫花牡荆素对二甲苯所致小鼠耳廊肿胀、鸡蛋清所致大鼠足肿胀以及醋酸所致小鼠毛细血管通透性增加均有明显的抑制作用。结论:紫花牡荆素具有明显的体内抗炎作用,为蔓荆子抗炎作用的有效成分。林珊 张宏 韩婷 吴锦忠 Khalid RAHMAN 秦路平 2007中西医结合学报2007,5,5:23
11农林废弃生物质吸附材料在水污染治理中的应用显示文摘环境污染问题已经成为人类社会可持续发展的巨大挑战之一,化工、冶炼及核燃料循环过程等排放的废水中含大量重金属离子、有机物及放射性核素等,若未经处理即排放会给环境带来了极大的危害。吸附法的效率高、操作简单、低成本且无副产物、可循环利用及无二次污染等优点使其成为废水处理的重要方法之一。由于农林废弃生物质成本低、来源丰富、绿色环保且可再生,以其为原料制备的吸附材料被广泛研究。本文主要针对以农林废弃生物质为原料制备的生物炭、纤维素及木质素为研究对象,综述了生物炭的制备及改性方法、天然纤维素及木质素的改性方法及其在水污染治理中的应用现状。从原材料、制备工艺、改性方法等方面总结分析了吸附材料的性能对水中污染物吸附的影响,提出了生物质基吸附材料在水污染治理应用中所存在的问题,并展望了未来的发展方向。易锦馨 霍志鹏 Abdullah M.Asiri Khalid A.Alamry 李家星 2019化学进展2019,31,5:22
12微生物碳酸盐岩的成因、分类以及问题与展望——来自华北地台寒武系微生物碳酸盐岩研究的启示显示文摘微生物碳酸盐岩以其漫长的地史分布、多样的产出环境、复杂的沉积构成和与微生物活动密切相关的特性而成为沉积学研究的焦点,同时也是沉积学研究的难点,被誉为'最难研究的沉积岩之一'。其研究的中心主要是钙化微生物席和微生物膜及其地质记录,即石化/成岩作用的产物。从成因着手,系统总结和梳理了2个类型的微生物群落,较薄的生物膜和较厚的微生物席,经过生物/有机矿化作用和石化/成岩作用形成微生物碳酸盐岩的过程。提出除微生物群落自身的复杂性和沉积过程的复杂性之外,多重状生物膜是导致微生物碳酸盐岩多样性的另外一个重要原因。以中国华北地台寒武系微生物碳酸盐岩的研究为基础,梳理了不同类型的微生物碳酸盐岩的沉积特征和分类依据。认为微生物碳酸盐岩应该置于Embry和Kloven描述的黏结岩类下,根据宏观组构可进一步分为叠层石、凝块石、核形石、层纹石和均一石5类,树形石不易独立成类而应归于凝块石。微生物碳酸盐岩为整个地质历史时期与微生物活动相关的生物/有机矿化作用过程研究提供了有用信息,不但是了解地球表层环境演变的一个重要窗口,而且还形成和储集了较大规模的油气,具有重要的科学意义和经济价值。王龙 Khalid Latif Muhammad Riaz 刘晓晔 2018地球科学进展2018,33,10:18
13结直肠癌造口术后患者社会心理适应现状及影响因素分析显示文摘目的了解结直肠癌造口术后患者的社会心理适应现状并探讨其影响因素,为结直肠癌造口术后患者造口护理干预提供依据。方法于2017年3月至2019年6月,选取就诊于湖南省肿瘤医院造口伤口护理中心门诊的结直肠癌造口术后患者作为调查对象,采用自制的一般资料问卷和社会心理适应量表对其进行调查。结果共调查造口患者200例,其社会心理适应量表得分为(42.46±12.99)分,处于中等水平。多元线性回归分析结果显示,工作情况、是否自行更换造口袋、造口术后时间及有无并发症是造口术后患者心理社会适应的影响因素。结论结直肠癌造口术后患者的社会心理适应水平处于中等水平;医护人员应通过开展针对性的健康宣教,增强患者自护能力,提高其社会心理适应水平,促进其身心健康。刘华云 李旭英 谌永毅 朱小妹 汤新辉 陈玉盘 韦迪 Khalid khan 2021上海护理2021,21,11:18
14Diagnostic dilemma of abdominal tuberculosis in non-HIV patients:An ongoing challenge for physicians显示文摘AIM: To assess the clinical features, yield of the diagnostic tests and outcome of abdominal tuberculosis in non-HIV patients. METHODS: Adult patients with discharge diagnosis of abdominal tuberculosis (based upon; positive microbiology, histo-pathology, imaging or response to trial of anti TB drugs) during the period 1999 to 2004 were analyzed. Patient’s characteristics, laboratory investigations, radiological, endoscopic and surgical findings were evaluated. Abdominal site involved (intestinal, peritoneal, visceral, and nodal) and response to treatment was also noted. RESULTS: There were 209 patients enrolled. One hundred and twenty-three (59%) were females. Symptoms were abdominal pain 194 (93%), fever 134 (64%), night sweats 99 (48%), weight loss 98 (47%), vomiting 75 (36%), ascites 74 (35%), constipation 64 (31%), and diarrhea 25 (12%). Sub-acute and acute intestinal obstruction was seen in 28 (13%) and 12 (11%) respectively. Radiological evidence of pulmonary tuberculosis was found in 134 (64%) patients. Basis of diagnosis of abdominal tuberculosis were radiology (Chest and barium X-Rays, Ultrasound and CT scan abdomen) in 111 (53%) and histo-pathology (tissue obtained during surgery, colonoscopy, CT or ultrasound guided biopsy, laparoscopy and upper gastro intestinal endoscopy) in 87 (42%) patients. Mycobacterium culture was positive in 6/87 (7%) patients and response to therapeutic trial of anti tubercular drugs was the basis of diagnosis in 5 (2.3%) patients. Predominant site of involvement by abdominal TB was intestinal in 103 (49%) patients, peritoneal in 87 (42%) patients, solid viscera in 10 (5%) and nodal in 9 (4%) patients. Response to medical treatment was found in 158 (76%) patients andadditionally 35 (17%) patients also underwent surgery. In a 425 ± 120 d follow-up period 12 patients died (eight post operative) and no case of relapse was noted. CONCLUSION: Abdominal TB has diverse and non- specific symptomatology. No single test is adequate for diagnosis of abdominal tuberculosis in all patients. Abdominal TB in non-HIV patients remains an ongoing diagnostic dilemma requiring a high index of clinical suspicion.Rustam Khan Shahab Abid Wasim Jafri Zaigham Abbas Khalid Hameed Zubair Ahmad 2006World Journal of Gastroenterology2006,12,39:17
15寒武系张夏组鲕粒滩中微生物碳酸盐岩主导的生物丘:以河北秦皇岛驻操营剖面为例显示文摘华北地台的寒武系苗岭统,大致包括毛庄组、徐庄组、张夏组和崮山组,这些组分别组成相应的三级沉积层序,在它们的顶部集中发育着鲕粒滩相灰岩而构成强迫型海退沉积,成为时间特化的相,代表着鲕粒主导的特别的寒武纪碳酸盐岩台地类型,表现在浅海陆架中大面积分布鲕粒滩,而且在这样的鲕粒滩中生长和发育着微生物碳酸盐岩主导的生物丘;河北省秦皇岛市驻操营剖面的张夏组上部鲕粒滩相灰岩中的生物丘正是上述现象最为典型的代表。虽然类似的现象曾经被描述为'藻坪'沉积,或者笼统地归为'微生物礁',但是,河北省秦皇岛市驻操营剖面的张夏组上部鲕粒滩相灰岩中的生物丘,以下现象不但将其特征化而且代表着壮观的沉积学现象:(1)在强迫型海退体系域的下部与鲕粒滩相灰岩交互产出的主要是柱状叠层石生物丘;(2)在张夏组顶部则以集中产出的均一石和树形石生物丘为特征;(3)下部的柱状叠层石生物丘中主要包括石松藻(Lithocodium)-孢网菌(Bacinella)状组构的钙化蓝细菌;(4)在上部集中产出的均一石与树形石生物丘,则发育着丝状钙化蓝细菌、基座菌(Hedstroemia)和附枝菌(Epiphyton)之类的多样化的钙化蓝细菌。由于石松藻(Lithocodium)-孢网菌(Bacinella)状组构的钙化蓝细菌是一种灭绝了的浅海生命形式,而且是不知道分类位置归属的生命形式,尤其是石松藻(Lithocodium)状组构近年来在寒武纪微生物碳酸盐岩研究中多被解释为'硅质海绵骨针的网状物'或'非骨针角质海绵骨骼纤维',再考虑到均一石自从命名以来很少描述在古老的地层记录之中,因此,驻操营剖面张夏组上部多样化微生物碳酸盐岩所主导的生物丘,以及生物丘中特别而且多样的钙化蓝细菌化石构成,为了解蓝细菌主导的光合作用微生物席复杂的钙化作用形成微生物碳酸盐岩提供了较为典型的实例。梅冥相 Khalid Latif 孟庆芬 胡媛 2019地质学报2019,93,1:17
16贻贝等六种软体动物磷脂的比较显示文摘对紫贻贝、栉孔扇贝、褶牡蛎、杂色蛤、缢蛏、毛蚶六种贝类的磷脂作了比较研究 ,对它们的出肉率、总脂、中性脂、极性脂、磷脂及其组分、脂肪酸的组成做了检测分析。结果表明 ,六种贝类的磷脂特性有一定的差异 ,牡蛎中磷脂酰肌醇含量特别高。心磷脂只在牡蛎和毛蚶中被检出 ,毛蚶中只含EPA ,而无DHA。六种贝类共同特点是磷脂酰胆碱与磷脂酰乙醇胺之和在 70林洪 吕青 Khalid Jamil 薛长湖 欧阳昌荣 王海英 2000水产学报2000,24,2:17
17基于隔直装置全局优化投切的直流偏磁治理方法显示文摘由于缺乏对直流电流全局分布的考虑,传统隔直装置投切方法容易造成区域内其他变压器出现中性点直流电流被动超标。为了有效地指导偏磁治理工作,提出一种基于隔直装置全局优化投切的偏磁治理方法。首先根据直流电位衰减规律确定交流系统建模范围,其次结合交流系统等效电阻网络、变电站与接地极地理位置分布情况,采用场–路耦合分析思想建立全局隔直装置优化投切数学模型,最后以全局中性点直流电流最大值最小为目标进行寻优,得到最优投切方案。通过宜昌地区电网实际参数验证所提方法(基于穷举法寻优)隔直效果优于传统方法,同时为了保证在交流系统规模扩大后寻优的效率,采用多种智能方法对优化问题进行求解,验证了智能算法同样可以实现趋近于穷举法的隔直效果。谢志成 林湘宁 李正天 郑颖 郭倩雯 Muhammad Shoaib Khalid Owolabi Sunday Adio 薄志谦 2017中国电机工程学报2017,37,24:16
18Distributed cooperative control of autonomous multi-agent UAV systems using smooth control显示文摘This paper addresses the cooperative control problem of multiple unmanned aerial vehicles(multi-UAV)systems.First,a new distributed consensus algorithm for second-order nonlinear multi-agent systems(MAS)is formulated under the leader-following approach.The algorithm provides smooth input signals to the agents’control channels,which avoids the chattering effect generated by the conventional sliding mode-based control protocols.Second,a new formation control scheme is developed by integrating smooth distributed consensus control protocols into the geometric pattern model to achieve three-dimensional formation tracking.The Lyapunov theory is used to prove the stability and convergence of both distributed consensus and formation controllers.The effectiveness of the proposed algorithms is demonstrated through simulation results.BELKACEM Kada MUNAWAR Khalid MUHAMMAD Shafique Shaikh 2020Journal of Systems Engineering and Electronics2020,31,6:16
19A survey on trust based detection and isolation of malicious nodes in ad-hoc and sensor networks显示文摘Adnan AHMED Kamalrulnizam ABU BAKAR Muhammad Ibrahim CHANNA Khalid HASEEB Abdul Waheed KHAN 2015Frontiers of Computer Science2015,9,2:15
20中国对虾肌动球蛋白变性后ATPase活性的研究显示文摘在中国对虾肌动球蛋白(Aotomyosin)经冷冻变性和热变性后,对Ca2+-ATPase、Mg2+-ATPase活性及蛋白质溶解度进行了研究。冷冻变性之后,肌动球蛋白Ca2+-ATPase活性呈逐渐下降趋势,一般贮藏温度越低,活性降低越快。热变性之后,肌动球蛋白Ca2+或Mg2+-ATPase活性都随温度升高而下降,但肌动球蛋白Ca2+或Mg2+-ATPase活性在35℃有一急剧下降的拐点,并分别在45℃、40℃附近低到0。由于蛋白质的变性。林洪 王长峰 李兆杰 Khalid Jamil 1996青岛海洋大学学报(自然科学版)1996,26,4:14
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