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| 1 | Gastroenterologist perceptions of faecal microbiota transplantation显示文摘AIM: To explore gastroenterologist perceptions towards and experience with faecal microbiota transplantation(FMT).METHODS: A questionnaire survey consisting of 17 questions was created to assess gastroenterologists' attitude towards and experience with FMT. This was anonymously distributed in hard copy format amongst attendees at gastroenterology meetings in Australia between October 2013 and April 2014. Basic descriptive statistical analyses were performed.RESULTS: Fifty-two clinicians participated. Twenty one percent had previously referred patients for FMT,8% more than once. Ninety percent would refer patients with Clostridium difficile infection(CDI) for FMT if easily available,37% for ulcerative colitis,13% for Crohn's disease and 6% for irritable bowel syndrome. Six percent would not refer any indication,including recurrent CDI. Eighty-six percent would enroll patients in FMT clinical trials. Thirty-seven percent considered the optimal mode of FMT administration transcolonoscopic,17% nasoduodenal,13% enema and 8% oral capsule. The greatest concerns regarding FMT were: 42% lack of evidence,12% infection risk,10% non infectious adverse effects/lack of safety data,10% aesthetic,10% lack of efficacy,4% disease exacerbation,and 2% inappropriate use; 6% had no concerns. Seventy seven percent believed there is a lack of accessibility while 52% had an interest in learning how to provide FMT. Only 6% offered FMT at their institution.CONCLUSION: Despite general enthusiasm,most gastroenterologists have limited experience with,or access to,FMT. The greatest concerns were lack of supportive evidence and safety issues. However a significant proportion would refer indications other than CDI for FMT despite insufficient evidence. These data provide guidance on where education and training are required. | Sudarshan Paramsothy Alissa J Walsh Thomas Borody Douglas Samuel Johan van den Bogaerde Rupert WL Leong Susan Connor Watson Ng Hazel M Mitchell Nadeem O Kaakoush Michael A Kamm | 2015 | World Journal of Gastroenterology2015，21，38： | 5 |
| 2 | Vasoactive in testinal Polypepatide Levels diseasein sigm oid idiopation and diverticular显示文摘 | Milner P Crowe R Kamm M A | 1990 | Gastroenterology1990，99，3： | 1 |
| 3 | Haemorrhoids: pathology, pathophysiology and aetiology显示文摘 | Loder P B Kamm M A Nicholls R J | 1994 | Br J Surg1994，81，7： | 1 |
| 4 | Erythromycin for the treatment of chronic intestinal pseudo-obstruction: description of six cases with a positive response显示文摘 | Emmanuel A V Shand A G Kamm M A | 2004 | Aliment Pharmacol Ther2004，19，6： | 1 |
| 5 | Reassessing artificial bowel sphincter 显示文摘 | MALFOUF A J VAIZEY C J KAMM M A | 2000 | Lancet2000，355，： | 1 |
| 6 | Non-surgical management of fecal incontinence 显示文摘 | CHEETHAM M J KENEFICK N J KAMM M A | 2001 | Hosp Med2001，62，： | 1 |
| 7 | 2D Vortex-Glass Transition with Tg=0Kin Tl2Ba2CaCu2O8 Thin Films due to High Magnetic Fields显示文摘 | Wen H H Radovan H A Kamm F M | 1998 | Phys Rev Lett1998，80，： | 1 |
| 8 | Effect of a novel prokinetic drug, R093877, on gastrointestinal transit in healthy volunteers 显示文摘 | Emmanuel A Kamm M Roy A | 1998 | Gut1998，42，4： | 1 |
| 9 | Laser Doppler flowmetry as a measure of extrinsic colonic innervation in functional bowel disease显示文摘 | Emmanuel A Kamm M | 2000 | Gut2000，46，： | 1 |
| 10 | Mechanisms of action of probiotics:recent advances显示文摘 | NG S C HART A L KAMM M A | 2009 | Inflamm Bowel Dis2009，15，2： | 1 |
| 11 | Response to a behavioural treatment, biofeedback, in constipated patients is associated with improved gut transit and autonomic innervation显示文摘 | AV Emmanuel M A Kamm | 2001 | Gut2001，49，： | 1 |
| 12 | Topical phenylephrine increases anal canal resting pressure in patients with fecal incontinence 显示文摘 | CHEETHAM M J KAMM M A PHILIPS R K S | 2001 | Gut2001，48，： | 1 |
| 13 | Me- chanical stress is communicated between different cell types to elicit matrix remodeling显示文摘 | SWARTZ M A TSCHUMPERLIN D J KAMM R D | 2001 | Proceedings of the National Academy of Sciences of the United States of America2001，98，11： | 1 |
| 14 | Perianal fistulizing Crohn's disease: a call to action显示文摘 | KAMM M A NG S C | 2008 | Clinical Gastroenterology and Hepatology~ the Oi''fieial Clinical Practice Journal of the American Gastroen terological Association2008，6，1： | 1 |
| 15 | Use of probiotics in the treatment of inflammatory bowel disease显示文摘 | Hart A L Stagg A J Kamm M A | 2003 | Clin Gastroenterol2003，36，2： | 1 |
| 16 | Gastrointestinal hormones in short bowel syndrome, Peptide YY may be the “colonic brake” togastric emptying显示文摘 | Nightingale J M Kamm M A ver der sijp J R | 1996 | Gut1996，39，2： | 1 |
| 17 | Review article:biological drugs in Crohn's disease显示文摘 | | 2006 | Aliment Pharmacol Ther2006，24，3： | 1 |
| 18 | Hereditary internal anal sphincter myopathy causing proctalgia fugax and constipation :A newly identified condition显示文摘 | Kamm M A Hoyle C H Burleigh D E | 1991 | Gastroenterology1991，100，： | 1 |
| 19 | Randomized,controlled trial of anal electrical stimulation for fecal incontinence显示文摘 | Gibbs A Kamm M A | 2006 | Dis Colon Rectum2006，49，2： | 1 |
| 20 | Debate: should mesalamine be used in Crohn's disease:comments and conclusions显示文摘 | Kamm M A | 2005 | Infiamm Bowel Dis2005，11，6： | 1 |
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