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| 1 | 聚类有效性评价综述显示文摘在聚类分析应用中,迫切需要一种客观公正的质量评价方法来评判聚类结果的有效性。为此,从外部评价法、内部评价法和相对评价法三个方面,归纳综述了常用的聚类有效性评价方法,并讨论了模糊聚类评价法和聚类最佳类别数的自动确定问题。 | 杨燕 靳蕃 KAMEL Mohamed | 2008 | 计算机应用研究2008，25，6： | 117 |
| 2 | 一种基于蚁群算法的聚类组合方法显示文摘蚂蚁等群居类昆虫被看作能解决复杂问题的分布式系统,研究者从它们的协作性能以及自组织、信息素通信、任务划分等机理中获得灵感,已在组合优化、通信网络、机器人等许多应用领域找到解决问题的新方法。聚类作为一种无监督的学习,能根据数据间的相似程度自动地进行分类。基于蚁群算法的聚类方法已经在当前数据挖掘研究中得到应用。本文提出的基于蚁群算法的聚类组合新方法,模仿多蚁群的协作性能,将运动速度类型各异的多个蚁群,独立而并行地进行聚类分析,然后组合其聚类结果为超图,再用蚁群算法对超图进行2次划分。实验结果表明,该方法能自动决定聚类的数目,聚类组合方法能明显改善聚类质量。 | 杨燕 靳蕃 Mohamed Kamel | 2004 | 铁道学报2004，26，4： | 39 |
| 3 | 微粒群优化算法研究现状及其进展显示文摘对进化计算中引起广泛兴趣的微粒群优化(PSO)算法的研究现状进行了考察,介绍了一些最新研究进展,包括:杂交PSO、基于邻域算子的PSO和基于不同搜索方向的PSO,并简要介绍了PSO在求解复杂优化问题如多目标优化和带约束优化中的优势。最后给出了一些应用实例,讨论了将来可能的研究内容。 | 杨燕 靳蕃 Kamel M | 2004 | 计算机工程2004，30，21： | 23 |
| 4 | Numerical Investigation of the Fluid Flow in Continuous Casting Tundish Using Analysis of RTD Curves显示文摘A detailed mathematical procedure of the optimization of the fluid flow in a tundish water model with and without flow control devices (weir and dam) was carried out using the commercial CFD code FLUENT 6.0. The (k-ε) two-equation model was used to model turbulence. The residence time distribution (RTD) curves were used to analyze the behavior of the flow in tundish. The location of flow control devices in the tundish was studied. The results show that the flow modifiers play an important role in promoting the floatation of nonmetallic inclusions in steel. Comparing the three geometric configurations that are considered (bare tundish, weir, weir+dam), the tundish equipped with the arrangement (weir+dam) is a best and optimal geometric configuration of tundish. | Moumtez Bensouici Ahmed Bellaouar Kamel Talbi | 2009 | Journal of Iron and Steel Research(International)2009，16，2： | 21 |
| 5 | 肝门部胆管癌的诊断、治疗选择与处理策略显示文摘肝门部胆管癌(HC)是一种少见的疾病,通常在60岁左右发病,预后较差;在美国,每年约有3 000例患者被诊断为该病,但仅有不到一半的人可以行手术治疗;有多种因素与HC的发病有关,最常见的有原发性硬化性胆管炎(PSC),胆石症以及寄生虫肝病。患者通常表现为腹痛、瘙痒、体质量减轻和黄疸。CT、MRI及超声可以用来发现胆道病损;逆行性胰胆管造影术(ERCP)及经皮肝胆管造影术(PTC)在评估肿块位置、长度的同时还可以行治疗性的胆汁引流。MRCP在辨别肿瘤延伸范围时同PTC及ERCP有相同的准确性,并且并发症较前两者少。HC的治疗方式主要为手术切除、放射治疗、化疗及光动力学治疗。残余肝脏胆汁引流有助于降低胆红素水平,进而促进残肝的生长;标准的治疗包括切缘为阴性切除(R0),范围为肝外胆管切除、肝切除及周围的淋巴结清扫术;局部的切除术是不适当的;淋巴结侵犯的程度、肿瘤的级别以及切缘的性质是重要的预后指标;如果无法行肿瘤切除,那么在经反复选择后的患者中实施肝移植术也是种可行的方式;尽管数据有限,化疗对于不可切除的患者来说仍有一定的作用;经手术切除的HC患者5年生存率约为10%~40%,然而即使为R0切除,复发率也高达50%~70%。由于这种疾病的复杂性,多种学科的综合治疗是较为理想的治疗方式。 | Kevin C.Soares Ihab Kamel David P.Cosgrove Joseph M.Herman Timothy M.Pawlik 冯铁成 李新营 | 2014 | 中国普通外科杂志2014，23，8： | 15 |
| 6 | Positioning patients for spine surgery: Avoiding uncommon position-related complications显示文摘Positioning patients for spine surgery is pivotal for optimal operating conditions and operative-site exposure. During spine surgery, patients are placed in positions that are not physiologic and may lead to complications. Perioperative peripheral nerve injury(PPNI) and postoperative visual loss(POVL) are rare complications related to patient positioning during spine surgery that result in significant patient disability and functional loss. PPNI is usually due to stretch or compression of the peripheral nerve. PPNI may present as a brachial plexus injury or as an isolated injury of single nerve, most commonly the ulnar nerve. Understanding the etiology, mechanism and pattern of injury with each type of nerve injury is important for the prevention of PPNI. Intraoperative neuromonitoring has been used to detect peripheral nerve conduction abnormalities indicating peripheral nerve stress under general anesthesia and to guide modification of the upper extremity position to prevent PPNI. POVL usually results in permanent visual loss. Most cases are associated with prolonged spine procedures in the prone position under general anesthesia. The most common causes of POVL after spine surgery are ischemic optic neuropathy and central retinal artery occlusion. Posterior ischemic opticneuropathy is the most common cause of POVL after spine surgery. It is important for spine surgeons to be aware of POVL and to participate in safe, collaborative perioperative care of spine patients. Proper education of perioperative staff, combined with clear communication and collaboration while positioning patients in the operating room is the best and safest approach. The prevention of uncommon complications of spine surgery depends primarily on identifying high-risk patients, proper positioning and optimal intraoperative management of physiological parameters. Modification of risk factors extrinsic to the patient may help reduce the incidence of PPNI and POVL. | Ihab Kamel Rodger Barnette | 2014 | World Journal of Orthopedics2014，5，4： | 12 |
| 7 | Antibacterial activity of Rosmarinus officinalis L.alone and in combination with cefuroxime against methicillin-resistant Staphylococcus aureus显示文摘Objective:To determine the antimicrobial activity of rosemary(Rosmarinus of ficinalis L.) and to investigate the synergistic effects of this extract combined with ceforuxime against methicillinresistant Staphylococcus aureus(MRSA).Methods:The inhibitory and bactericidal activities of rosemary ethanol extract,alone and in combination with cefuroxime,were studied.Results:The minimum inhibitory concentrations(MICs) of the ethanol extract of rosemary were in the range of 0.39-3.13 mg/mL.The minimum bactericidal concentrations(MBCs) were usually equal to or double that MICs.The antimicrobial activity of combinations of the ethanol extract of rosemary and cefuroxime indicated their synergistic effects against all MRSAs.Conclusions:The present work clearly demonstrates that rosemary has a key role in the elevation of susceptibility toβ-lactams. | Naser Jarrar Awni Abu-Hijleh Kamel Adwan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，2： | 10 |
| 8 | Procalcitonin and intestinal ischemia:A review of the literature显示文摘Intestinal ischemia is common after emergency gastrointestinal or cardiovascular surgery.At present,there are no diagnostic tools for the early diagnosis of intestinal ischemia.In the last decade,procalcitonin(PCT)has been suggested as a marker of this condition.Here,we review the use of PCT as a diagnostic tool for intestinal ischemia.Two reviewers independently searched the Pub Med and EMBASE databases for articles on intestinal ischemia and PCT.They then considered(1)the criteria applicable to preclinical and clinicaldata;and(2)PCT’s predictive value in the diagnosis of intestinal ischemia.Article quality was rated according to the STAndards for Reporting of Diagnostic accuracy.Between 1993 and 2014,seven studies(including two preclinical studies and five clinical studies)dealt with the use of PCT to diagnose intestinal ischemia.Procalcitonin’s sensitivity,specificity,positive predictive value and negative predictive value ranged between 72%and 100%;68%and 91%;27%and 90%and 81%and 100%,respectively.The area under the receiver operating characteristic curve ranged from 0.77 to 0.92.In view of the preclinical and clinical data,we consider that PCT can be used in daily practice as a tool for diagnosing intestinal ischemia. | Cyril Cosse Charles Sabbagh Sad Kamel Antoine Galmiche Jean-Marc Regimbeau | 2014 | World Journal of Gastroenterology2014，20，47： | 9 |
| 9 | Adaptive mode switching of hypersonic morphing aircraft based on type-2 TSK fuzzy sliding mode control显示文摘This paper presents a novel adaptive mode switching scheme for hypersonic morphing aircraft with retracted winglets based on type-2 Takagi-Sugeno-Kang(TSK) fuzzy sliding mode control. For each of retracting and stretching modes, a specific sliding mode controller has been adopted. Drawing upon input/output linearization to globally linearize the nonlinear model of the hypersonic aircraft at first, a type-2 TSK fuzzy logic system is devised for robust mode switching between these sliding mode controllers. For rapid stabilization of the system, the adaptive law for mode switching is designed using a direct constructive Lyapunov analysis.Simulation results demonstrate the stability and smooth transition using the proposed switched control scheme. | JIAO Xin FIDAN Baris JIANG Ju KAMEL Mohamed | 2015 | Science China(Information Sciences)2015，58，7： | 8 |
| 10 | Pancreatic injury in patients with septic shock: A literature review显示文摘Sepsis and septic shock are life threatening condition associated with high mortality rate in critically-ill patients. This high mortality is mainly related to the inadequacy between oxygen delivery and cellular demand leading to the onset of multiorgan dysfunction. Whether this multiorgan failure affect the pancreas is not fully investigated. In fact, pancreatic injury may occur because of ischemia, overwhelming inflammatory response, oxidative stress, cellular apoptosis and/or metabolic derangement. Increased serum amylase and/or lipase levels are common in patients with septic shock. However, imaging test rarely reveal significant pancreatic damage. Whether pancreatic dysfunction does affect the prognosis of patients with septic shock or not is still a matter of debate. In fact, only few studies with limited sample size assessed the clinical relevance of the pancreatic injury in this group of patients. In this review, we aimed to describe the epidemiology and the physiopathology of pancreatic injury in septic shock patients, to clarify whether it requires specific management and to assess its prognostic value. Our main finding is that pancreatic injury does not significantly affect the outcome in septic shock patients. Hence, increased serum pancreatic enzymes without clinical features of acute pancreatitis do not require further imaging investigations and specific therapeutic intervention. | Anis Chaari Karim Abdel Hakim Kamel Bousselmi Mahmoud Etman Mohamed El Bahr Ahmed El Saka Eman Hamza Mohamed Ismail Elsayed Mahmoud Khalil Vipin Kauts William Francis Casey | 2016 | World Journal of Gastrointestinal Oncology2016，8，7： | 8 |
| 11 | A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1显示文摘 | Giuseppe Militello Mohammed Rabiul Hosen Yuliya Ponomareva Pascal Gellerts Tyler Weirick David John Sajedah Mahmoud Hindi Kamel Mamchaoui Vincent Mouly Claudia Doring Lidan Zhang Miki Nakamura Ashok Kumar So-ichiro Fukada Stefanie Dimmeler Shizuka Uchida | 2018 | Journal of Molecular Cell Biology2018，10，2： | 7 |
| 12 | Association between vitamin D receptor polymorphisms and multiple sclerosis: systematic review and meta-analysis of case-control studies显示文摘维生素 D 受体(VDR ) 多型性作为潜在的贡献者被学习了到多重硬化(MS ) 。然而,出版了研究关于学习设计和检测的效果的意义不同。这研究的目的是确定与在用元分析的 MS 的 VDR 多型性接近的 TaqI, BsmI, ApaI 和 FokI 联系的风险的大小。为系统的评论和元分析指南跟随比较喜欢的报导项目,我们进行了文学的系统的搜索和元分析。亚群分析被执行从选择学习特征检测异质的潜在的来源。概括风险的稳定性用敏感分析被评估。元分析从 13 盒子控制研究包括了 3300 个案例和 3194 控制的一个总数。没有重要协会,在 TaqI 和 BsmI 多型性和 MS 风险之间发现。在 ApaI 多型性和 MS 风险之间的协会是重要的在同型结合并且 codominant 模型(P= 0.013 并且 P= 0.031,分别地) ,建议 AA ApaI 遗传型可能是一个重要 MS 风险因素。出版年和年龄显著地影响了在 TaqI 多型性和 MS 之间的协会(P= 0.014 并且 P= 0.010,分别地) ,它显示主要 T 等位基因的保护的效果。AA ApaI 和 FF FokI 遗传型是为 MS 的重要风险因素。在 TaqI 多型性和 MS 风险之间的协会被学习特征显著地影响。 | Kalthoum Tizaoui Wajih Kaabachi Agnes Hamzaoui Kamel Hamzaoui | 2015 | Cellular & Molecular Immunology2015，12，2： | 7 |
| 13 | New Results on Discrete-time Delay Systems Identification显示文摘A new approach for simultaneous online identification of unknown time delay and dynamic parameters of discrete-time delay systems is proposed in this paper.The proposed algorithm involves constructing a new generalized regression vector and defining the time delay and the rational dynamic parameters in the same vector.The gradient algorithm is used to deal with the identification problem.The effectiveness of this method is illustrated through simulation. | Sada Bedoui Majda Ltaief Kamel Abderrahim | 2012 | International Journal of Automation and computing2012，9，6： | 7 |
| 14 | Unknown Inputs Observer for a Class of Nonlinear Uncertain Systems: An LMI Approach显示文摘This paper deals with the simultaneous estimation of states and unknown inputs for a class of Lipschitz nonlinear systems using only the measured outputs. The system is assumed to have bounded uncertainties that appear on both the state and output matrices. The observer design problem is formulated as a set of linear constraints which can be easily solved using linear matrix inequalities (LMI) technique. An application based on manipulator arm actuated by a direct current (DC) motor is presented to evaluate the performance of the proposed observer. The observer is applied to estimate both state and faults. | Kamel Mohamed Mohammed Chadli Mohamed Chaabane | 2012 | International Journal of Automation and computing2012，9，3： | 6 |
| 15 | 创伤性脑损伤后蛛网膜下腔出血与长期卒中风险的关系(英文)显示文摘BACKGROUND Recent studies suggest that traumatic brain injury(TBI)is a risk factor for subsequent ischemic stroke,even years after the initial insult.The mechanisms of the association remain unclear.The presence of traumatic subarachnoid hemorrhage(t SAH)may mediate the effect of TBI on long-term stroke risk,as it has previously been linked to short-term vasospasm and delayed cerebral ischemia.METHODS Using administrative claims data,we conducted a retrospective cohort study of acute care hospitalizations.Patients discharged with a first-recorded diagnosis of t SAH were followed for a primary diagnosis of stroke.They were matched to patients with TBI but not t SAH.Cox proportional hazards modeling was used to assess the association between t SAH and stroke while adjusting for covariates.RESULTS:We identified 40 908 patients with TBI(20 454 patients with t SAH)who were followed for a mean of 4.3+1.8 years.A total of 531 had an ischemic stroke after discharge.There was no significant difference in stroke risk between those with t SAH(1.79%;95%confidence interval[CI]1.54%-2.08%)versus without t SAH(2.12%;95%CI 1.83%-2.44%).The same pattern was found in adjusted analyses even when the group was stratified by age-group or by proxies of TBI severity.CONCLU-SIONS:Our findings do not support a role of t SAH in mediating the association between TBI and protracted stroke risk.Further study is required to elucidate the mechanisms of long-term increased stroke risk after TBI. | Morris NA Cool J Merkler AE Kamel H | 2017 | 中华神经外科疾病研究杂志2017，16，4： | 6 |
| 16 | Testicular torsion in undescended testis:A persistent challenge显示文摘Objective:To evaluate the management and outcomes of patients who presented with torsion of an undescended testis and review the reported series in the literature.Methods:The case records of 13 patients operated for testicular torsion involving undescended testis were retrospectively reviewed.The medical records included age at presentation,medical history,physical examination,operative findings and the results of follow-up.The diagnosis of torsion of undescended testis was made clinically and confirmed by inguinal exploration.Results:In six cases the testis was preserved and orchiopexy was performed,while in seven cases orchidectomy was performed due to testicular gangrene in six patients and testicular tumor discovered peroperatively in one case.Mean duration of symptoms at time of surgery in the orchiopexy group was 6.5 h and in the orchidectomy group was 21.2 h.From six patients treated by orchiopexy,two patients suffered from testicular atrophy at a mean of 24 months.Conclusion:Testicular torsion in undescended testis is still diagnosed with delay which may affect testicular salvage.The importance of examination of external genital organs is highlighted which should be routinely included by emergency physicians in physical examination for abdominal or groin pain. | Sahbi Naouar Salem Braiek Rafik El Kamel | 2017 | Asian Journal of Urology2017，4，2： | 5 |
| 17 | Phase II Study of Everolimus in Patients with Metastatic Colorectal Adenocarcinoma Previously Treated with Bevacizumab-, Fluoropyrimidine-, Oxaliplatin-, and Irinotecan-Based Regimens显示文摘 | Kimmie Ng Josep Tabernero Jimmy Hwang Emilio Bajetta Sunil Sharma Salvatore A. Del Prete Edward R. Arrowsmith David P. Ryan Michaela Sedova Jin Jin Kamel Malek Charles S. Fuchs | 2013 | Clinical Cancer Research2013，，14： | 4 |
| 18 | Comparative Genomic Study of the Thioredoxin Family in Photosynthetic Organisms with Emphasis on Populus trichocarpa显示文摘Populus trichocarpa 和 Vitis vinifera 定序的最近的染色体,木质的植物的二个模型,蜀黍二色,用 C4 新陈代谢的 monocot ,并且苔藓 Physcomitrella 圣餐盘的一个模型,与过不同生活方式,繁殖模式,生物特点,和生理学的有机体和光合的有机体染色体的可获得性允许比较 genomic 研究的性能。Thioredoxins (Trxs ) 是在在所有亚 cellular 分隔空间在场、在许多生物化学的反应包含的许多目标酶涉及二硫化物桥的减小的小无所不在的蛋白质。为这些酶编码的基因在这些最新定序的染色体被识别了并且注解。基因内容,组织和分发与另外的光合的有机体相比,导致一个精制分类。这分析表明更高的植物和藓苔类的植物与水藻和 cyanobacteria 相比并且到非光合的有机体有一个更复杂的家庭,自从白杨展览为典型、不正常的 thioredoxins 和 thioredoxin reductases 编码的 49 基因,也就是三分之一个多于象 Oryza sativa 和 S 那样的 monocots。二色。在白杨的 Trxs 的更高的数字被基因复制部分在 Trx m, h,和 nucleoredoxin 班解释。注意在班把块称为的象 Trx 一样上与强调对白杨基因被给予的详细规格,象 thioredoxin 一样, lilium 类型和 nucleoredoxins 的 thioredoxins,它没在以前的 genomic 深入地被描述学习。 | Kamel Chibani Gunnar Wingsle Jean-Pierre Jacquot Eric Gelhaye Nicolas Rouhier | 2009 | Molecular Plant2009，2，2： | 4 |
| 19 | Antibacterial activities of some plant extracts alone and in combination with different antimicrobials against multidrug-resistant Pseudomonas aeruginosa strains显示文摘Objective:To evaluate the possible in vitro interaction between ethanolic extracts of Rhus coriaria[R.coriaria)(seed),Sacropoterium spinosum(S.spinosum)(seed),Rosa damascena(R. damascene)(flower) and certain known antimicrobial drugs including oxytetracycline HCl, penicillin C,cephalexin,sulfadimethoxine as sodium,and enr of loxacin.This synergy study was carried out against 3 clinical strains of multidrug-resistant Pseudomonas aeruginosa (P.aeruginosa).Methods:Evaluation of synergy interaction between plant extracts and antimicrobial agents was carried out using microdilution method.Results:The results of this study showed that there is a decrease in the MIC in case of combination of ethanolic plant extracts and test antimicrobial agents.The most interesting result was that the combination between R. coriaria and these antibiotics,showed a high decrease in minimum inhibitory concentration(MIC), and a strong bactericidal activity against these strains.Conclusions:These results may indicate that combinations between R.coriaria extract and these antibiotics could be useful in fighting emerging drug-resistance P.aeruginosa,which may due to that R.coriaria extract contain natural inhibitors working by different mechanisms or inhibiting efflux pumps.Now we have experiments underway leading to the identification of the active molecules present in R.coriaria.Further,in vivo experiments are needed to confirm pseudomonal protection. | Ghaleb Adwan Bassam Abu-Shanab Kamel Adwan | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，4： | 4 |
| 20 | Effectiveness of royal jelly supplementation in glycemic regulation:A systematic review显示文摘BACKGROUND Royal jelly(RJ)has been observed to have therapeutic properties in diabetic individuals,including the reduction of high blood sugar.This systematic review synthesized existing evidence to investigate the effectiveness of RJ supplementation in managing measures of blood glucose.AIM To determine the effectiveness of RJ supplementation on glycemic responses in healthy and non-insulin dependent diabetic adults,as well as animal models of diabetes.METHODS This was a systematic review employing the PRISMA strategy.Peer-reviewed,published articles were extracted from several databases using key words related to target population,intervention and outcome and hand-selected for inclusion.Included articles proceeded to data extraction phase,where information on target parameters and effectiveness of treatment was summarized.Following this,the risk of bias for each included study was evaluated.Then,the long-term and immediate effectiveness of RJ supplementation in glycemic control were assessed using the Grading of Recommendations,Assessment,Development and Evaluations(GRADE)tool,which rates the quality of evidence.RESULTS Of 168 articles extracted from database searching,eighteen were included for analysis in this systematic review.Across the studies,studied populations,intervention styles and outcome measures were largely heterogeneous.Despite this,the results in studies indicate a general trend of positive effect of RJ in glycemic regulation in vitro and in vivo.Additionally,some dose-dependent glycemic effects were observed,along with some large effect sizes.The risk of bias for human and animal studies is generally low-unclear risk,although lack of blinding is a serious concern in both categories.Overall,as per the GRADE tool,the quality of evidence is low,and very low for long-term and immediate effectiveness of RJ,respectively.A major limitation affecting evidence quality is the heterogeneity among included studies.Fasting blood glucose and glucose clearance appear to be most affected by RJ supplementation.CONCLUSION Quality of evidence suggesting that RJ is an effective modulator of glycemic regulation is low for long-term effects of RJ,and very low for immediate effects. | Kamel Omer Maxwell J Gelkopf Genevieve Newton | 2019 | World Journal of Diabetes2019，10，2： | 3 |
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