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19篇 您的检索式：作者名="KAINDL H"

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		题名	作者	年代	出处	被引量
	1	Binding pathway determines norepinephrine selectivity for the human β_(1)AR over β_(2)AR显示文摘Beta adrenergic receptors(βARs)mediate physiologic responses to the catecholamines epinephrine and norepinephrine released by the sympathetic nervous system.While the hormone epinephrine binds β_(1)AR and β_(2)AR with similar affinity,the smaller neurotransmitter norepinephrine is approximately tenfold selective for the β_(1)AR.To understand the structural basis for this physiologically important selectivity,we solved the crystal structures of the human β_(1)AR bound to an antagonist carazolol and different agonists including norepinephrine,epinephrine and BI-167107.Structural comparison revealed that the catecholamine-binding pockets are identical between β_(1)AR and β_(2)AR,but the extracellular vestibules have different shapes and electrostatic properties.Metadynamics simulations and mutagenesis studies revealed that these differences influence the path norepinephrine takes to the orthosteric pocket and contribute to the different association rates and thus different affinities.	Xinyu Xu Jonas Kaindl Mary J.Clark Harald Hübner Kunio Hirata Roger K.Sunahara Peter Gmeiner Brian K.Kobilka Xiangyu Liu	2021	Cell Research2021，31，5：	2
	2	The Sukari gold mine,eastern Desert-Egypt:structural setting,mineralogy and fluid inclusion study显示文摘	Helmy H.M Kaindl R Fritz H Loizenbauer J		0，，：	1
	3	Acute ascending motoric paraplegia following intrathecal chemotherapy for treatment of acute lymphoblastic leukemia in children: case reports and review of the literature显示文摘	Roll N Boehm H Kaindl AM	2006	Kiln Padiatr2006，218，6：	1
	4	Incidence of septic and throm boembolic related deaths after splenectomy in adults显示文摘	PIMPL W KAINDL H	1989	Br J Surg1989，76，5：	1
	5	Biostructure derived ceramics显示文摘	Sieber H Kaindl A Greil P	2000	Ceramic Engineering and Science Proceedings2000，21，4：	1
	6	Biomorhic cellular ceramics显示文摘	Sieber H Honann C Kaindl A	2000	Advanced Engineering Materials2000，2，3：	1
	7	Light-weight cellular ceramics from biologically-derived preforms显示文摘	SIEBER H KAINDL A SCHWARZE D	2000	Cfi-Ceramie Forum International2000，77，12：	1
	8	Experimental Determinations and Quantum-chemical Calculations of the Vibrational Spectra of β-ZnB4O7 and β-CaB4O7显示文摘	Kaindl R Sohr G Huppertz H	2013	Spectrochim Acta A2013，116，：	1
	9	Biomorphic cellular ceramics显示文摘	SIEBEtl H HONANN C KAINDL A	1999	Advanced Engineering Materials1999，2，3：	1
	10	Light weight cellular ceramics from biologically-derived preforms 显示文摘	SEIBER H KAINDL A SCHWARZE D	2000	cfi/BerDKG2000，77，：	1
	11	Biomorphic cellular ceramics 显示文摘	SIEBER H HOFFMANN C KAINDL A etal	2000	Adv Eng Mater2000，2，：	1
	12	Bidirectional heuristic search reconsidered显示文摘	Kaindl H Kainz G	1997	Journal of Artificial Intelligence Research1997，7，：	1
	13	Acute ascending motoric paraplegia following intrathecal chemotherapy for treatment of acute lymphoblastic leukemia in children: case report and review of the literature显示文摘	ROLF N BOEHM H KAINDL AM	2006	Klin Padiatr2006，218，6：	1
	14	Biomorphic cellular ceramics显示文摘	Sieber H Hoffmann C Kaindl A	2000	Adv Eng Mater2000，2，3：	1
	15	Biomorphic cellular ceramics 显示文摘	Sieber H Hoffmann C Kaindl A	2000	Advanced Engineering Materials2000，2，3：	1
	16	Biomorphic cellular ceramics显示文摘	Sieber H Hoffmann C Kaindl A	2000	Adv Eng Mater2000，2，3：	1
	17	Superstructure of mul- lite-type KA19OI4 显示文摘	LAZIC B KRUGER H KAINDL R	2013	Chem Mater2013，25，3：	1
	18	Biomorphic cellular ceramics显示文摘	Sieber H Hoffmann C Kaindl A	2000	Adv Eng Mater2000，2，3：	1
	19	Biomorphic cellular eeramics显示文摘	SIEBER H HOFFMANN C KAINDL A	2000	Adv Eng Mater2000，2，3：	1

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