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| 1 | Role of quorum sensing in bacterial infections显示文摘Quorum sensing(QS) is cell communication that is widely used by bacterial pathogens to coordinate the expression of several collective traits, including the production of multiple virulence factors, biofilm formation, and swarming motility once a population threshold is reached. Several lines of evidence indicate that QS enhances virulence of bacterial pathogens in animal models as well as in human infections; however, its relative importance for bacterial pathogenesis is still incomplete. In this review, we discuss the present evidence from in vitro and in vivo experiments in animal models, as well as from clinical studies, that link QS systems with human infections. We focus on two major QS bacterial models, the opportunistic Gram negative bacteria Pseudomonas aeruginosa and the Gram positive Staphylococcus aureus, which are also two of the main agents responsible of nosocomial and wound infections. In addition, QS communication systems in other bacterial, eukaryotic pathogens, and even immune and cancer cells are also reviewed, and finally, the new approaches proposed to combat bacterial infections by the attenuation of their QS communication systems and virulence are also discussed. | Israel Castillo-Juárez Toshinari Maeda Edna Ayerim Mandujano-Tinoco María Tomás Berenice Pérez-Eretza Silvia Julieta García-Contreras Thomas K Wood Rodolfo García-Contreras | 2015 | World Journal of Clinical Cases2015，3，7： | 15 |
| 2 | 颈椎压缩性骨折伴脊髓损伤保守治疗后的局部后凸进展显示文摘颈椎屈曲压缩性骨折常伴有小关节面明显移位、颈椎力线偏移以及灾难性的神经功能障碍,因此建议及时施行外科手术。但是,一些患者的小关节面尚能维持平整,颈椎力线可,此外,由于伤后可能同时存在多发性损伤和/或失血性休克,常无法施行手术,因此保守治疗仍是可取的选择。目前鲜有报道评估保守治疗颈椎屈曲压缩性骨折伴脊髓损伤的长期疗效。本研究回顾性分析此类患者的临床特征、影像学表现和远期治疗结果,同时探讨患者损伤后局部后凸进展的潜在危险因素。 | Yokota K Maeda T Kawano 白朝晖 王建华 | 2019 | 中国骨科临床与基础研究杂志2019，11，3： | 4 |
| 3 | Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review显示文摘 | H Maeda J Wu T Sawa Y Matsumura K Hori | 2000 | Journal of Controlled Release2000，，1： | 3 |
| 4 | Protein release from collagen matrices 显示文摘 | FUJIOKA K MAEDA M HOJO T | 1998 | Advance d Drug Delivery Reviews1998，31，： | 2 |
| 5 | Prognostic value of vascular endothelial growth factor in gastriccarcinoma显示文摘 | MAEDA K CHUNG Y S OGAWA Y | 1996 | Cancer1996，77，5： | 2 |
| 6 | Respiratory health associated with exposure to automobile exhaust Ⅲ :results of a cross-sectional study in 1987,and repeated pulmonary function tests from 1987 to 1990 显示文摘 | Nakai S Nitta H Maeda K | 1999 | Arch of Environ Health1999，54，： | 2 |
| 7 | Plasma brain natriuretic peptde level as a biochemical marker of morbidity and mortality in patienst with asymptomatic or minimally symptomatic left ventficular dysfunction 显示文摘 | TASUTAMOTO T WADA A MAEDA K | 1999 | Eur Heart J1999，20，24： | 1 |
| 8 | A T-shaped musculomucosal buccal flap method for cleft palate surgery显示文摘 | Maeda K Ojimi H Utsugi R | 1987 | Plast Reconstr Surg1987，79，6： | 1 |
| 9 | Plasma brain natriuretic peptide as biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction显示文摘 | Maeda K Tsutamoto T Wada A | 1998 | Am Heart J1998，135，51： | 1 |
| 10 | Practical control method for ultra-precision positioning using ballscrew mechanism显示文摘 | Maeda G J Sato K | 2008 | Precision Engineering2008，32，4： | 1 |
| 11 | Synthesis and Characterization of Novel Biodegradable Copolyeater by Transreaction of Poly ( Ethylene Terephthalate) with Copoly( Succinic Anhydride/Ethylene Oxide) 显示文摘 | Maeda Y Maeda T Yamaguchi K | 2000 | J Polym Sci Part A : Polym Chem2000，38，： | 1 |
| 12 | Video-assisted neck surgery for thyroid and parathyroid disease显示文摘 | Shimizu K Minami S | 2002 | Biomed Pharmacother2002，56，1： | 1 |
| 13 | Development of the automatic system for pneumatic caisson显示文摘 | KODAKI K NAKANO M MAEDA S | 1997 | Automation in Construction1997，6，3： | 1 |
| 14 | Periodontal ligament cells secrete the factor that inhibits osteoclastic differentiation and function: the factor is osteoprotegerin/ osteoclastogenesis inhibitory factor显示文摘 | Wada N Maeda H Tanabe K | 2001 | J Periodontal Res2001，36，1： | 1 |
| 15 | Antiherpetic activities of sul- fated polysaccharides from green algae 显示文摘 | Lee J B Hayashi K Maeda M | 2004 | Planta Med2004，70，9： | 1 |
| 16 | The lack of the C - terminal domain of adipose triglyeeride li- pase causes neutral lipid storage disease through impaired interactions with lipid droplets显示文摘 | KOBAYASHI K INOGUCHI T MAEDA Y | 2008 | Journal of Clinical En- docrinology and Metabolism2008，93，： | 1 |
| 17 | Diabetic neuropathy and nerveregeneration显示文摘 | Yasuda H Terada M Maeda K | 2003 | Prog Neurobiol2003，69，4： | 1 |
| 18 | Aggravation of brain injury after transient focal ischemia in p53-deficient mice显示文摘 | Maeda K Hata R Gillardon F Hossmann KA | 2001 | Mol Brain Res2001，88，12： | 1 |
| 19 | The relationship of preoperative magnetic resonance imaging findings and closed sestem drainage in the recurrence of chronic subdural hematoma显示文摘 | TSUTSUMI K MAEDA K LIJIMA A | 1997 | J Neurosurg1997，87，6： | 1 |
| 20 | Triple Primary Intracranial Tumors of Diffierent Cell Types:a Case Report显示文摘 | Miyagi A Maeda K Sugawara T | 1995 | No Shinkei Geka Neurological Surgery1995，23，6： | 1 |
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