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| 1 | THE CASE STUDY ON THE EFFECT OF CO_2 IN CAVE ATMOSPHERE ON STABILITY OF SPELEOTHEM SCENERY IN YAOLIN CAVE, ZHEJIANG PROVINCE, CHINA显示文摘Because of the development of tourist activities and the facilities in the show cave, the closed system of show cave has been changed into the complicated open system. The great number of the visitors and the landscape lights give great deal of thermoenergy to the show cave system, especially the high intensive lights make the temperature nearby goes up very fast and reduce the humidity. After the visitors leaving and the lights switching off, the temperature goes down and humidity increases even upto saturation, the condensation taken place. In the dry seasons, the cave humidity is relative low, even down to 40 50 percent. The administrations of show cave rushes the water to clean the touristic trails and keep the high humidity as to protect the cave environment. Under the function of artificial readjustment, the humidity of Yaolin cave atmosphere reaches to 97-100 percent throughtout the year. | Song Linhua Yang Jingrong Lin Junshu Group of Karstology and Speleology, Institute of Geography, CAS, Beijing 100101 People’s Republic of ChinaWang Laihong Administration of Yaolin Cave, Tonglu County, Zhejiang Province, 311500 People’s Republic | 1997 | Journal of Geographical Sciences1997，7，3： | 8 |
| 2 | Porous Ruthenium Selenide Nanoparticle as a Peroxidase Mimic for Glucose Bioassay显示文摘Nanozyme is a promising field that offers the substitution for natural enzymes using various nanomaterials.Various nanoma-terials with peroxidase-like activity were investigated.Among them,transition metal chalcogenides were explored as promis-ing nanozymes due to their excellent enzyme-mimicking activities.However,ruthenium selenide has not been studied as a peroxidase mimic because of the difficulty for synthesis.Herein,we prepared ruthenium selenide nanomaterial with ordered mesoporous structure(P-RuSe_(2))employing KIT-6 silica as the template.The composition and structure of P-RuSe_(2) were fully characterized.Further,its peroxidase-like activity was investigated.P-RuSe_(2) possessed excellent peroxidase-mimicking activ-ity,which catalyzed the oxidation of peroxidase substrates,including 3,3′,5,5′-tetramethylbenzidine,o-phenylenediamine,and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)in the presence of H_(2)O_(2).Moreover,P-RuSe_(2) exhibited higher peroxidase-like activity when compared with several representative nanozymes as well as bulk RuSe_(2).To demonstrate its potential applications,the colorimetric detection systems for H_(2)O_(2) and glucose were successfully constructed based on P-RuSe_(2) nanozyme. | Wen Cao Junshu Lin Faheem Muhammad Quan Wang Xiaoyu Wang Zhangping Lou Hui Wei | 2019 | Journal of Analysis and Testing2019，3，3： | 1 |
| 3 | Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice显示文摘Cancer and impaired tissue wound healing with ageing are closely related to the quality of life of the elderly population.Given the increased incidence of cancer and the population ageing trend globally,it is very important to explore how ageing impairs tissue wound healing and spontaneous cancer.In a murine model of DSS-induced acute colitis and AOM/DSS-induced colitis-associated cancer(CAC),we found ageing significantly decreases intestinal wound healing and simultaneous CAC initiation,although ageing does not affect the incidence of AOM-induced,sporadic non-inflammatory CRC.Mechanistically,reduced fibroblasts were observed in the colitis microenvironment of ageing mice.Through conditional lineage tracing,an important source of fibroblasts potentially derived from intestinal smooth muscle cells(ISMCs)was identified orchestrating intestinal wound healing and CAC initiation in young mice.However,the number of transformed fibroblasts from ISMCs significantly decreased in ageing mice,accompanied by decreased intestinal wound healing and decreased CAC initiation.ISMCs-fibroblasts transformation in young mice and reduction of this transformation in ageing mice were also confirmed by ex-vivo intestinal muscular layer culture experiments.We further found that activation of YAP/TAZ in ISMCs is required for the transformation of ISMCs into fibroblasts.Meanwhile,the reduction of YAP/TAZ activation in ISMCs during intestinal wound healing was observed in ageing mice.Conditional knockdown of YAP/TAZ in ISMCs of young mice results in reduced fibroblasts in the colitis microenvironment,decreased intestinal wound healing and decreased CAC initiation,similar to the phenotype of ageing mice.In addition,the data from intestine samples derived from inflammatory bowel disease(IBD)patients show that activation of YAP/TAZ also occurs in ISMCs from these patients.Collectively,our work reveals an important role of the ageing stromal microenvironment in intestinal wound healing and CAC initiation.Furthermore,our work also identified a potential source of fibroblasts involved in colitis and CAC. | Yi Liu Yanhong Ji Ruiyi Jiang Chao Fang Gang Shi Lin Cheng Yinan Zuo Yixin Ye Xiaolan Su Junshu Li Huiling Wang Yuan Wang Yi Lin Lei Dai Shuang Zhang Hongxin Deng | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 0 |
| 4 | APPROACH TO KARST SOLUTION PROCESS RESPONSES ON CLIMATE显示文摘Based upon the studies of solutional rates with environment from South China to North China over a range of about 30 。 latitude, this paper discusses some of the consequence with equations. The response model shows that the precipitation is the most important factor influencing the rate of solutional denudation except the lithology, the relief etc., but it is an integrational action on the solution process; at the same time, temperature acts as a threshold in bringing the precipitation into play. These suggest that firstly, the solutional denudation process is a comprehensive response to the multiple factors; secondly, karst solution is a complex response process to the climate, and as an integrated exogenic process under the bioclimate. | Lin Junshu Li Juzhang Fang Jinfu Institute of Geography, CAS, Beijing 100101 People’s Republic of China | 1997 | Journal of Geographical Sciences1997，7，3： | 0 |
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