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您的检索式：作者名="Junjun LANG"
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| 1 | ZokorDB: tissue specific regulatory network annotation for non-coding elements of plateau zokor显示文摘Background:Plateau zokor inhabits in sealed burrows from 2,000 to 4,200 meters at Qinghai-Tibet Plateau.This extreme living env ironment makes it a great model to study animal adaptation to hypoxia,low temperature,and high carbon dioxide concentration.Methods:We provide an integrated resource,ZokorDB,for tissue specific regulatory network annotation for zokor.ZokorDB is based on a high-quality draft genome of a plateau zokor at 3,300 m and its transcriptional profiles in brain,heart,liver,kidney,and lung.The conserved non-coding elements of zokor are annotated by their nearest genes and upstream transcriptional factor motif binding sites.Results:ZokorDB provides a general draft gene regulatory network(GRN),Le?potential transcription factor(TF)binds to non-coding regulatory elements and regulates the expression of target genes(TG).Furthermore,we refined the GRN by incorporating matched RNA-seq and DNase-seq data from mouse ENCODE project and reconstructed five tissue-specific regulatory networks.Conclusions:A web-based,open-access database is developed for easily searching,visualizing,and downloading the annotation and data.The pipeline of non-coding region annotation for zokor will be useful for other non-model species.ZokorDB is free available at the website(bigd.big.ac.cn/zokordb/). | Jingxue Xin Junjun Hao Lang Chen Tao Zhang Lei Li Luonan Chen Wenmin Zhao Xuemei Lu Peng Shi Yong Wang | 2020 | Quantitative Biology2020，8，1： | 0 |
| 2 | Complete moment convergence for weighted sums of widely orthant-dependent random variables and its application in nonparametric regression models显示文摘We establish some results on the complete moment convergence for weighted sums of widely orthant-dependent(WOD)random variables,which improve and extend the corresponding results of Y.F.Wu,M.G.Zhai,and J.Y.Peng[J.Math.Inequal.,2019,13(1):251–260].As an application of the main results,we investigate the complete consistency for the estimator in a nonparametric regression model based on WOD errors and provide some simulations to verify our theoretical results. | Lu CHENG Junjun LANG Yan SHEN Xuejun WANG | 2022 | Frontiers of Mathematics in China2022，17，4： | 0 |
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