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2篇 您的检索式:作者名="Judith A.Roether"
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1Incorporation of bioactive glass nanoparticles in electrospun PCL/chitosan fibers by using benign solvents显示文摘The use of bioactive glass(BG)particles as a filler for the development of composite electrospun fibers has already been widely reported and investigated.The novelty of the present research work is represented by the use of benign solvents(like acetic acid and formic acid)for electrospinning of composite fibers containing BG particles,by using a blend of PCL and chitosan.In this work,different BG particle sizes were investigated,namely nanosized and micron-sized.A preliminary investigation about the possible alteration of BG particles in the electrospinning solvents was performed using SEM analysis.The obtained composite fibers were investigated in terms of morphological,chemical and mechanical properties.An in vitro mineralization assay in simulated body fluid(SBF)was performed to investigate the capability of the composite electrospun fibers to induce the formation of hydroxycarbonate apatite(HCA).Liliana Liverani Jonas Lacina Judith A.Roether Elena Boccardi Manuela S.Killian Patrik Schmuki Dirk W.Schubert Aldo R.Boccaccini 2018Bioactive Materials2018,3,1:4
2Bioactive glass based scaffolds coated with gelatin for the sustained release of icariin显示文摘Gelatin-coated,3D sponge-like scaffolds based on 45S5 bioactive glass were produced using the foam replication technique.Compressive strength tests of gelatin-coated samples compared to uncoated scaffolds showed significant strengthening and toughening effects of the gelatin coating with compressive strength values in the range of cortical bone.Additionally,the crosslinked gelatin network(using either caffeic acid or N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride(EDC)/N-hxdroxysuccinimide(NHS)as crosslinking agent)was shown to be a suitable candidate for the sustained release of the bioactive molecule icariin.Concerning bioactivity of the produced scaffolds,characterization by FTIR and SEM indicated the formation of hydroxyapatite(HA)in all samples after immersion in simulated body fluid(SBF)for 14 days,highlighting the favorable combination of mechanical robustness,bioactivity and drug delivery capability of this new type of scaffolds.Theresa Reiter Tanja Panick Katharina Schuhladen Judith A.Roether Jasmin Hum Aldo R.Boccaccini 2019Bioactive Materials2019,4,1:1
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