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| 1 | 中国慢性胆囊炎、胆囊结石内科诊疗共识意见(2014年,上海)显示文摘1前言1.1本共识意见的产生背景和程序临床症状、体征和实验室检查对诊断慢性胆囊炎、胆囊结石有重要作用,但缺乏特异性。超声检查通常是影像学检查的第一步。目前,国内消化内科尚未制订有循证医学证据支持的慢性胆囊炎、胆囊结石的诊断和治疗共识意见。为规范慢性胆囊炎、胆囊结石的诊断和治疗,中华消化杂志编辑部特邀请国内部分消化内外科专家和放射科专家组成《中国慢性胆囊炎、胆囊结石内科诊疗共识意见》专家委员会,依据我国慢性胆囊疾病的流行趋势、最近的研究成果和循证医学证据,并参照《消化疾病诊疗指南》(第3版)及国际相关指南和最新研究成果,共同讨论制订了本共识意见,旨在为慢性胆囊炎、胆囊结石的内科治疗提供合理与规范的诊治策略。 | Editorial Board of Chinese Journal of Digestion | 2015 | 临床肝胆病杂志2015，31，1： | 157 |
| 2 | 大数据时代显示文摘分析了大数据的产生,归纳了大数据的'大'这个特点,可以用多样化、海量、快速、灵活和复杂'4V+1C'来概括;从大数据的存储问题、处理问题、部门之间的信息是否融合几个方面论述了大数据对通信、医药、天文学、宇宙学、材料科学、气象学等领域产生影响;最后,提出了几条应对措施。 | (Editorial Office of 《Journal of China Academy of Electronics and Information Technology》, Beijing 100846,China) | 2013 | 中国电子科学研究院学报2013，8，1： | 44 |
| 3 | Chinese expert consensus statement on the diagnosis and treatment of fulminant myocarditis显示文摘Fulminant myocarditis is primarily caused by infection with any number of a variety of viruses. It arises quickly, progresses rapidly, and may lead to severe heart failure or circulatory failure presenting as rapid-onset hypotension and cardiogenic shock,with mortality rates as high as 50%–70%. Most importantly, there are no treatment options, guidelines or an expert consensus statement. Here, we provide the first expert consensus, the Chinese Society of Cardiology Expert Consensus Statement on the Diagnosis and Treatment of Fulminant Myocarditis, based on data from our recent clinical trial(NCT03268642). In this statement, we describe the clinical features and diagnostic criteria of fulminant myocarditis, and importantly, for the first time,we describe a new treatment regimen termed life support-based comprehensive treatment regimen. The core content of this treatment regimen includes(i) mechanical life support(applications of mechanical respirators and circulatory support systems,including intraaortic balloon pump and extracorporeal membrane oxygenation),(ii) immunological modulation by using sufficient doses of glucocorticoid, immunoglobulin and(iii) antiviral reagents using neuraminidase inhibitor. The proper application of this treatment regimen may and has helped to save the lives of many patients with fulminant myocarditis. | Daowen Wang Sheng Li Jiangang Jiang Jiangtao Yan Chunxia Zhao Yan Wang Yexin Ma Hesong Zeng Xiaomei Guo Hong Wang Jiarong Tang Houjuan Zuo Li Lin Guanglin Cui Section of Precision Medicine Group of Chinese Society of Cardiology,Editorial Board of Chinese Journal of Cardiology &Working Group of Adult Fulminant Myocarditis | 2019 | Science China(Life Sciences)2019，62，2： | 18 |
| 4 | Current gene therapy for stomach carcinoma显示文摘Gastric cancer is common in China [1-42],and its early diagnosis and treatment in advanced stage are difficult [31-50].In recent years ,gene study in cancer is a hotspot ,and great progress has been achieved [41-80] .Cancer gene therapy has shifted from the imagination into the laboratory and clinical trials. | Chang-Tai Xu~1 Lian-Tian Huang~1 Bo-Rong Pan~2 1 Editorial Department,the Journal of Fourth Military Medical University2 Oncology Center,Xijing Hospital,Fourth Military Medical University,169 Changle Xilu,Xi’an 710032,Shaanxi Province,China | 2001 | World Journal of Gastroenterology2001，7，6： | 16 |
| 5 | Adsorption properties of nitrobenzene in wastewater with silica aerogels显示文摘The adsorption properties of nitrobenzene from wastewater by hydrophobic silica aerogels were investigated.The effects of adsorption intensity by pH value,adsorption temperature,adsorption time and the amount of the silica aerogels were studied.The adsorption principle and mechanism of silica aerogels adsorbing nitrobenzene were discussed along with the Freundlich equation.The results showed that the adsorption intensity of the hydrophobic silica aerogels could reach 68.76% at better adsorption conditions of adsorption temperature 25°C,pH value 8.35,the amount of SiO2 aerogels dosage 3.33 g/L,and adsorption time of 30 min,and that the adsorption properties were related to the hydrophobility of aerogels,surface area of organic solution,structure of aerogels. | CUI Sheng1,LIU XueYong2,LIU Yu2,SHEN XiaoDong1,LIN BenLan1,3,HAN GuiFang1 & WU ZhanWu1 1 College of Material Science and Engineering,Nanjing University of Technology,Nanjing 210009,China 2 Institute of Chemical Materials,CAEP,Mianyang 621900,China 3 Editorial Board of Journal,Nanjing University of Technology,Nanjing 210009,China | 2010 | Science China(Technological Sciences)2010，53，9： | 13 |
| 6 | The 150 most important questions in cancer research and clinical oncology series: questions 6–14显示文摘To accelerate our endeavors to overcome cancer,Chinese Journal of Cancer has launched a program of publishing 150most important questions in cancer research and clinical oncology.In this article,nine more questions are presented as followed.Question 6.Why do nasopharyngeal carcinomas rarely metastasize to the brain?Question 7.Can distant spread of cancer cells be blocked by inhibiting the remodeling of high endothelial venules in the sentinel lymph node?Question 8.What sort of live-imaging techniques can be developed to directly observe the dynamic processes of metastasis?Question 9.How does chronic hepatitis prevent liver metastasis from colorectal cancer?Question 10.How many types of host cells contribute to forming the pre-metastatic niche in the lung favorable for metastasis?Question 11.Why do cancers rarely metastasize to the small bowel?Question 12.Why do glioblastomas rarely metastasize outside the central nervous system?Question 13.Despite increased understanding of the molecular genetic events leading to the development and progression of high-grade gliomas,these tumors are the most therapeutically refractory among all human cancers.What then would be the most effective therapeutic approaches to treat what in essence can be regarded as a whole brain malignancy,since even a surgical resection of greater than 99%of tumor tissues is invariably associated with recurrence?Question 14.The blood–brain barrier(BBB)effectively limits a wide variety of potential therapeutic agents from reaching glioma cells widely dispersed in the brain.What therapeutic approaches can be used to breach the BBB and allow therapeutic agents to seek out and kill these tumor cells? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，3： | 11 |
| 7 | The 150 most important questions in cancer research and clinical oncology series:questions 15-24显示文摘To accelerate our endeavors to overcome cancer,Chinese Journal of Cancer has launched a program of publishing 150most important questions in cancer research and clinical oncology.In this article,10 more questions are presented as follows.Question 15:Can tumor-induced erythrogenesis provide qualified red blood cells for carrying oxygen to distant organs?Question 16:Can we overcome tumor resistance to platinum-containing antineoplastic drugs by activating the sensitivity factors in the tumor?Question 17:How can a cancer cell stay dormant for years?Question 18:Why do cancer cells use distinct transcriptomic and proteomic programs to reach the same metastatic phenotype?Question 19:Why do some cancers regress spontaneously?Question 20:What are the regulatory mechanisms occurring in donor cells that determine selective sorting of biological content into vesicles and their biological consequences in recipient cells?Are the genetic transfer and exchange of biological messages between cells transient?Is the phenotypic manipulation of recipient cells temporary or prolonged and persistent?If extracellular vesicles possess immune-modulatory potential,how could they be exploited for immune interventions and cancer immunotherapy?Presumably the cargo of extracellular vesicles reflects the cells of their origin and can be used for cancer diagnosis,how could the uniform/stringent capture criteria be met universally for applying EVs in point-of-care diagnostics for cancer patients?Question 21:Can we use self-sampling technologies to monitor the tumor genetic alterations for more precise targeted therapy?Can we cure a heterogeneous tumor by sequentially targeting the driver molecules?Question 22:Can we postpone the onset of non-infection-related cancers?Question 23:How many types of cells can jointly form the tumor vasculature to provide blood supply for tumor progression?Question 24:How tumor cells transmit their epigenetic features to daughter cells and maintain the malignant phenotype? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，4： | 8 |
| 8 | The 150 most important questions in cancer research and clinical oncology series:Questions 25–30显示文摘To accelerate our endeavors to overcome cancer, Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology. In this article, 6 more questions are presented as followed. Question 25: Does imprinting of immune responses to infections early in life predict future risk of childhood and adult cancers? Question 26: How to induce homogeneous tumor antigen expression in a heterogeneous tumor mass to enhance the efficacy of cancer immunotherapy? Question 27: Could we enhance the therapeutic effects of immunotherapy by targeting multiple tumor antigens simultaneously or sequentially? Question 28: Can immunotargeting to cytokines halt cancer metastasis? Question 29: How can we dynamically and less-invasively monitor the activity of CD8^+ T killer cells at tumor sites and draining lymph nodes? Question 30: How can the immune system destroy the niches for cancer initiation? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，5： | 7 |
| 9 | Hemodynamic Effects of Inhaled Nitric Oxide in Patients with Pulmonary Hypertension.显示文摘Twelve patients with pulmonary hypertension (primary pulmonary hypertension in 3 cases, secondary to recurrent pulmonary embolism in 4 cases, chronic obstructive pulmonary disease in 2 cases and complicated with congeni- | Zhao Yiju et al. Cardiovascular Institute and Fu Wai Hospital. CAMS Beij- ing 100037. National Medical Journal of China. | 1995 | Chinese Medical Journal1995，，9： | 7 |
| 10 | The 150 most important questions in cancer research and clinical oncology series:questions 50-56显示文摘Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology, which sparkle diverse thoughts, interesting communications, and potential collaborations among researchers all over the world. In this article, seven more questions are presented as followed. Question50. When tumor cells spread from primary site to distant sites, are they required to be 'trained' or 'armed' in the bone marrow niche prior to colonizing soft tissues? Question 51. Are there tipping points during cancer progression which can be identified for manipulation? Question 52. Can we replace molecular biomarkers by network biomarkers?Question 53. Are conventional inhibitors of key cellular processes such as cell proliferation and differentiation more effective than targeted chemotherapeutics that antagonize the downstream cell signaling network via cell-surface receptors such as epidermal growth factor receptor(EGFR), vascular endothelial growth factor receptor(VEGFR) and c-Met, or intracellular receptors such as androgen receptor(AR) and estrogen receptor(ER), by drugs like erlotinib,sunitinib and cabozantinib, or enzalutamide and tomoxifen? Question 54. How can we robustly identify the candidate causal event of somatic genome alteration(SGA) by using computational approach? Question 55. How can we systematically reveal the immune evasion mechanism exploited by each tumor and utilize such information to guide targeted therapy to restore immune sensitivity? Question 56. Can the nasopharyngeal carcinoma(NPC) patients with sarcomatoid carcinoma(SC) subtype benefit from more specific targeted therapy? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，8： | 5 |
| 11 | 立足服务,精益求精——庆祝本刊创刊45周年显示文摘回顾45年的发展历程,总结了期刊的发展情况和积累的基本经验,展望未来的发展目标,提出了努力的方向。 | Editorial Board of Journal of Experimental Technology and Management | 2008 | 实验技术与管理2008，25，11： | 4 |
| 12 | The 150 most important questions in cancer research and clinical oncology series:questions 76-85显示文摘Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology to promote cancer research and accelerate collaborations. In this article, 10 questions are presented as followed. Question 76. How to develop effective therapeutics for cancer cachexia? Question 77.How can we develop preclinical animal models to recapitulate clinical situations of cancer patients for more effective anti-cancer drug development? Question 78. How can we develop novel effective therapeutics for pancreatic cancer and hepatocellular carcinoma? Question 79. What are the true beneficial mechanisms of antiangiogenic therapy in cancer patients? Question 80. How to approach the complex mechanisms of interplay among various cellular and molecular components in the tumor microenvironment? Question 81. Can tissue oxygenation improve the efficacy of conventional chemotherapy on cancer? Question 82. Can tissue oxygenation improve the efficacy of radiotherapy on digestive system tumors including liver cancer? Question 83. Can we integrate metabolic priming into multimodal management of liver cancer? Question 84. Has the limit of anti-androgen strategy in prostate cancer treatment been reached by the new generation of anti-androgen drugs? Question 85. Can we identify individuals with early-stage cancers via analyzing their clinical and non-clinical information collected from social media, shopping history, and clinical, pathological, and molecular traces? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，11： | 3 |
| 13 | Entropy correction of charged black hole via fermions tunneling beyond semi-classical approximation显示文摘Motivated by the idea of tunneling beyond semi-classical approximation of Majhi et al., we discuss entropy correction of Dirac particles tunneling from the Reissner-Nordstrm black hole with a global monopole. To get the corrections correctly, we regard the proportionality constants of quantum correction terms to the semi-classical term of action as the inverse of the square of the Planck Length but not that of the Planck Mass. Our study shows that corrections to the Bekenstein-Hawking entropy, namely the logarithmic term and the inverse area term, may be reproduced as the quantum effect is considered. | ZENG XiaoXiong 1 , LI Ling 2 & HU XinYun 3 1 Journal of Sichuan University of Arts and Science, Dazhou 635000, China 2 Department of Maths and Finance-Economics, Sichuan University of Arts and Science, Dazhou 635000, China 3 Library of Sichuan University of Arts and Science, Dazhou 635000, China | 2010 | Science China(Physics,Mechanics & Astronomy)2010，53，1： | 3 |
| 14 | The 150 most important questions in cancer research and clinical oncology series:questions 57-66显示文摘Since the beginning of 2017,Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology,which sparkle diverse thoughts,interesting communications,and potential collaborations among researchers all over the world.In this article,10 more questions are presented as followed.Question 57.What are the major stresses that drive the formation,progression,and metastasis of a cancer? Question 58.What is the mechanism responsible for altering an acidic intracellular pH and a basic extracellular pH in normal tissue cells to a basic intracellular pH and an acidic extracellular pH in cancer cells,a fundamental and yet largely ignored phenomenon? Question 59.Where are the tumor-associated plasma microRNAs from in cancer patients? Question 60.Can we identify mechanisms employed by tumor subpopulations to evade standard therapies and seed relapse/metastatic tumors before treatment? Question 61.Why are mutation rates in epidermal growth factor receptor(EGFR) and erb-b2 receptor tyrosine kinase 2(ERBB2) higher in lung cancer from never smokers than that from smokers? Question 62.Does tumor vasculogenic mimicry contribute to the resistance against antiangiogenic therapy in renal cancer? Question 63.What molecular targeted drugs would be effective for non-clear cell renal cell carcinoma(RCC),especially metastatic papillary RCC and chromophobe RCC? Question 64.Can it be more effective by targeting both the vascular endothelial growth factor receptor(VEGFR) and MET signaling pathways in sporadic metastatic papillary renal cell carcinoma(RCC)? Question 65.What are the predictive biomarkers that may be used to identify the renal cell carcinoma(RCC) patients who can benefit from immune checkpoint inhibitor treatment? Question 66.How do we identify predictive molecular biomarkers to stratify clear cell renal cell carcinoma patients for targeted therapies? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，9： | 3 |
| 15 | 传感器基础知识问答显示文摘无论是无线传感网还是物联网,包括将来可能的泛在网,传感器技术都是其中最关键的技术之一。但是一般人对传感器知识了解甚少,所以在此对传感器的基础知识和常见类型做一些简单介绍。 | RFID Ubiquitous Journal Editor | 2010 | 射频世界2010，，1： | 2 |
| 16 | Electronic Structure of Doped Trans-Polyacetylene显示文摘The behavior of electronic structures of doped trans-polyacetylene is revealed by a simple method. (C 24H 26) +n is used to simulate p-type doped trans-polyacetylene at various doping concentrations. The electronic structure is calculated by CNDO/2 method. These calculations show that at low doping level, the decrease of electronic energy compensates the increase of elastic energy, thus the bond alternation exists, and the charge carriers are solitons. When doping level is high, the increase of elastic energy is larger than the decrease of electronic energy, the bond alternation disappears, solitons no longer exist, and polyacetylene is in a metalic state. | Ren Da-zhi 1,2, Zhuang Wei 2, Wang Jun 2 1. Wuhan University Journals Press,Wuhan 430072,Hubei,China 2. School of Physics and Technology, Wuhan University, Wuhan 430072,Hubei,China | 2002 | Wuhan University Journal of Natural Sciences2002，7，1： | 2 |
| 17 | Chinese Guideline for Percutaneous Coronary Intervention in Patients with Left Main Bifurcation Disease显示文摘The coronary left main(LM)artery is characterized by large caliber,length varying from<8 to>15 mm,and 2 large daughter vessels branching from it;it supplies blood to a large area(>75%)of the myocardium.LM bifurcation lesion is defined as the presence of atherosclerosis involving either or both of the 2 daughter vessels.Thus,the optimal strategy of revascularization for diseased LM has been an interesting research topic for a long time.With developments in percutaneous techniques,design,and materials of drug-eluting stents;intravascular imaging;new generation of antiplatelet medications;and particularly recent pooled evidence from randomized clinical trials comparing percutaneous coronary intervention with coronary artery bypass grafting,implantation of a drug-eluting stenting with or without other approved techniques is considered an important therapeutic approach for LM bifurcation lesions.Mirroring the anatomical complexity of the LM,stenting LM bifurcations is technically demanding,and intraprocedural complications can be catastrophic given the large amount of jeopardized myocardium.Therefore,the Chinese Society of Cardiology designed a writing committee with members from 3 working groups(ie,clinical research,intravascular imaging and physiology,and interventional cardiology)for the first time,to write a guideline on percutaneous treatment for LM bifurcation lesions,with view to improve the procedural quality and clinical outcomes.This guideline consists of introduction,anatomical description of the LM tree,risk stratification,strategies of revascularization,antiplatelet strategy,follow-up,and long-term management for patients with LM bifurcation lesions. | Chinese Society of Cardiology,Chinese Medical Association Editorial Board of Chinese Journal of Cardiology Shaoliang Chen Yaling Han | 2022 | Cardiology Discovery2022，2，3： | 2 |
| 18 | The 150 most important questionsin cancer research and clinical oncology series:questions 40-49显示文摘Since the beginning of 2017,Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology,which sparkle diverse thoughts,interesting communications,and potential collaborations among researchers all over the world.In this article,10 more questions are presented as followed.Question 40.Why do mice being used as tumorigenesis models raised in different places or different conditions possess different tumor formation rate? Question 41.How could we generate more effective anti-metastasis drugs? Question 42.What is the molecular mechanism underlying heterogeneity of cancer cachexia in patients with the same pathologic type? Question 43.Will patients with oligo-metastatic disease be curable by immunotherapy plus stereotactic body radiotherapy? Question 44.Can the Warburg effect regulation be targeted for cancer treatment? Question 45.Why do adenocarcinomas seldom occur in the small intestine? Question 46.Is Epstein-Barr virus infection a causal factor for nasal natural killer/T cell lymphoma formation? Question 47.Why will not all but very few human papillomavirusinfected patients eventually develop cervical cancer? Question 48.Why do cervical carcinomas induced by human papilloma virus have a low mutation rate in tumor suppressor genes? Question 49.Can viral infection trigger lung cancer relapse? | Chinese Journal of Cancer | 2017 | Chinese Journal of Cancer2017，36，7： | 2 |
| 19 | Scientific statement of the Chinese Society of Cardiology(CSC) on using of renin angiotensin system blockers in patients with cardiovascular disease and COVID-19显示文摘The coronavirus disease 2019(COVID-19), which is caused by SARS-CoV-2, has become a worldwide public health crisis. Published clinical data from China and other countries have shown a much higher risk of developing COVID-19 and dying from the disease among the elderly, especially among those who had preexisting hypertension, cardiovascular diseases(CVD) and diabetes mellitus[1]. | Ya-Ling HAN Yu-Ming LI Chang-Sheng MA the Editorial Board of Chinese Journal of Cardiology 无 | 2020 | Journal of Geriatric Cardiology2020，17，5： | 2 |
| 20 | Acknowledgments to reviewers of World Journal of Biological Chemistry显示文摘Many reviewers have contributed their expertise and time to the peer review,a critical process to ensure the quality of World Journal of Biological Chemistry.The | Many reviewers have contributed their expertise and time to the peer review,a critical process to ensure the quality of World Journal of Biological Chemistry.The editors | 2011 | World Journal of Biological Chemistry2011，2，9： | 2 |
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