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10篇 您的检索式:作者名="Josh N"
    题名 作者 年代 出处 被引量
1Effects of tempera- ture on events in the infection cycle of two clonal lineages of Phy- tophthora in显示文摘Josh Marcelo N M Luiz A M Fxtuardo S G M 2009Plant Disease2009,93,5:1
2Transient diffusion of ion-implanted B in Si: Dose, time, and matrix dependence of atomic and electrical profiles 显示文摘 JANSSEN K T F JOSH F F 1990J Appl Phys1990,68,6:1
3Lattice Boltzmann method for multi-component,non-continuum mass diffusion显示文摘JOSH]A S PERACCHIO A A GREW K N 0,,:1
4Ionic liquid crystals of imidazolium salts with a pendant hydroxyl group 显示文摘Josh Y Z Chen J N Lei J S 2006J Mater Chem2006,16,29:1
5Pre- and post-exposure protection against Western equine encephalitisvirus after single inoculation with adenovirus vector expressing interferon alpha 显示文摘Wu Josh Q H Barab6 N D Huang Ying-min 2007Virology2007,369,1:1
6Trends in the management of anorectal melanoma:A multiinstitutional retrospective study and review of the world literature显示文摘BACKGROUND Anorectal melanoma(ARM)is a rare disease with a poor prognosis.Evidence on optimal treatment is limited and surgical management varies widely.We hypothesized that the frequency of abdominoperineal resection used as primary treatment of ARM has decreased over the past several decades.AIM To update our understanding of outcomes for patients with ARM and analyze management trends around the world.METHODS This is a multi-institutional,retrospective study of patients treated for ARM at 7 hospitals.Hospitals included both large,academic,tertiary care centers and smaller,general community hospitals.Using prospectively maintained institutional tumor registries,we identified 24 patients diagnosed with ARM between January 2000 and May 2019.We analyzed factors prognostic for recurrence and survival.We then used Cox regression to measure overall survival(OS)and melanoma-specific survival.We also performed a literature review to assess trends in surgical management and outcomes.RESULTS Of the 24 patients diagnosed with ARM,12(50.0%)had local,8(33.3%)regional,and 4(16.7%)distant disease at diagnosis.Median time to recurrence was 10.4 mo[interquartile range(IQR)7.5-17.2]with only 2 patients(9.3%)not developing recurrence following surgical resection.Median OS was 18.8 mo(IQR 13.5-33.9).One patient is still alive without recurrence at 21.4 mo from diagnosis;no other patient survived 5 years.Primary surgical management with abdominoperineal resection(APR)vs wide excision(WE)did not lead to differences in OS[hazard ratio=1.4(95%CI:0.3-6.8)].Review of the literature revealed geographic differences in surgical management of ARM,with increased use of WE in the United States and Europe over time and more frequent use of APR in Asia and India.There was no significant improvement in survival over time.CONCLUSION There is wide variation in the management of ARM and survival outcomes remain poor regardless of approach.Surgical management should aim to minimize morbidity.Josh Bleicher Jessica N Cohan Lyen C Huang William Peche T Bartley Pickron Courtney L Scaife Tawnya L Bowles John R Hyngstrom Elliot A Asare 2021World Journal of Gastroenterology2021,27,3:1
7Complete protection of mice against a lethal dose challenge of western equine en- cephalomyelitis virus after immunization with an adenovirus-vec- tored vaccine 显示文摘Wu Josh Q H Barab6 N D Chan D 2007Vaccine2007,25,22:1
8Refractory thrombotic thrombocytopenic purpura associated with primary Sjgren′s syndrome treated with Rituximab:a case report显示文摘Toumeh A Josh N Narwal R 2014Am J Ther2014,21,2:1
9A Default Temporal Logic for Regulatory Conformance Checking显示文摘DINESH N JOSH I A K LEE I 2008A Default Temporal Logic for Regulatory Conformance Checking2008,,:1
10Mobiles in Malawi: A Text Message-Based Intervention to Bridge the Patient-Physician Gap in the Rural Developing World显示文摘MaPrnud N Rodriguez J Nesbit Josh 2010Global Pulse2010,6,1:1
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