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| 1 | GRP78 upregulation-induced increase in cisplatin sensitivity of SPCA1 lung cancer cells显示文摘背景葡萄糖调整了蛋白质 78 ( GRP78 ),一个 endoplasmic 蜂窝胃(嗯)女伴,在许多 cancers.In 在化疗抵抗起一个关键作用这研究,我们调查了 A23187 和它的协会在房间是的人的肺癌症房间线 SPCA1.Methods SPCA1 与 chemotherapeutical 敏感导致到 cisplatin 的 GRP78 的起来规定有在在 mRNA 水平的 GRP78 的不同 concentrations.The 表示的 A23187 的 pretreated 被 RT-PCR 分析;在蛋白质水平的 GRP78 的表示被西方的弄污决定, immunofluorescence assay.Cell 幸存被 MTT assay.Cell apoptosis 决定被流动 cytometry.Results 分析在 mRNA 和蛋白质层次的 GRP78 的表示被 A23187 显然在 SPCA1 房间导致,与由在 mRNA 水平的2.1褶层并且由在与 control.There 相比的蛋白质水平的3.8褶层的 GRP78 的举起是分析表明了的一条剂量依赖者 response.Survival 曲线那 | ZHANG Li-chuan WANG Jia-rui ZHAO Long WANG Tao WU Jing FAN Su-fang CHEN Li-xia SHAO Shu-juan Joseph Molnar WANG Qi | 2011 | Chinese Medical Journal2011，，20： | 3 |
| 2 | Comparative organizational properties and interorganizational interdependence显示文摘 | Molnar Joseph J | 1978 | Sociology and Social Research1978，，63： | 1 |
| 3 | Sound Policies Forfood Security: The Role of Culture and Social Organization 显示文摘 | Joseph J Molnar | 2000 | Review of agricultural economics2000，21，2： | 1 |
| 4 | Acceleration of Integra Incorporation in Complex Tissue Defects with Subatmospheric Pressure显示文摘 | Joseph A. Molnar Anthony J. DeFranzo Anoush Hadaegh Michael J. Morykwas Perry Shen Louis C. Argenta | 2004 | Plastic and Reconstructive Surgery2004，，： | 1 |
| 5 | Ultrasound absorption and entropy production in biological tissue:a novel approach to anticancer therapy显示文摘 | Liaofu Luo Joseph Molnar Hui Ding | 2006 | Diagnostic Pathology2006，1，： | 1 |
| 6 | Physiochemical attack against solid tumors based on the reversal of direction of entropy flow:an attempt to introduce thermodynamics in anticancer therapy显示文摘 | Liaofu Luo Joseph Molnar Hui Ding | 2006 | Diagnostic Pathology2006，1，： | 1 |
| 7 | Mantle dynamics,uplift of the Tibetan plateau and the Indian monsoon显示文摘 | Molnar P England P Joseph M | 1993 | Reviews of Geophysics1993，31，4： | 1 |
| 8 | Antimicrobial and antiplasmid activities of essential oils显示文摘 | Zsuzsanna Schelz Joseph Molnar Judit Hohmann | 2006 | Fitoterapia2006，，77： | 1 |
| 9 | Antimierobial and antiplasmid activities of essential oils显示文摘 | Zsuzsanna Schelz Joseph Molnar Judit Hohmann | 2006 | Fitoterapia2006，77，4： | 1 |
| 10 | Mantle dynamics, uplift of the Tibetan plateau and the Indian monsoon 显示文摘 | Molnar P England P Joseph M | 1993 | Reviews of Geophysics1993，31，4： | 1 |
| 11 | Antimicrobial and antiplasmid activities of essential oils 显示文摘 | Zsuzsanna Schelz Joseph Molnar Judit Hohmann | 2006 | Fitoterapia2006，77，： | 1 |
| 12 | Antiplasmid effect of promethazine in mixed bacterial cultures 显示文摘 | Annamaria Molnar Leonard Amaral Joseph Molnar | 2003 | International Journal of Antimicrobial Agents2003，22，： | 1 |
| 13 | Mantle dynamics, uplift of the Tibatan plateau and the Indian monsoon 显示文摘 | Molnar P England P Joseph M | 1993 | Reviews of Geophysics1993，31，4： | 1 |
| 14 | Reversal of multidrug resistance and antitumor promoting activity of 3-oxo-6β-hydroxy-β-amyrin isolated from Pistacia integerrima显示文摘The bioactive triterpenoid 3-oxo-6-β-hydroxy-β-amyrin(1)has been isolated from multiple plant sources.In this study,chloroform fraction of Pistacia integerrima extract was processed for the isolation of the compound.The compound identity was confirmed by advanced spectroscopy technique.X-ray crystallography was applied for molecular structure confirmation.In addition,compound 1 was screen for its activity on reversal of MDR(multidrug resistance)mediated by P-gp(P-glycoprotein).This was accomplished by using rhodamine123 exclusion on multidrug-resistant human ABCB1 gene transfected mouse T-lymphoma cell line.Outcomes revealed that MDR reversing effect was comparable to verapamil as positive control in vitro.Treatment of TPA-induced tumor promotion with 3-oxo-6β-hydroxy-β-amyrin led to reduction in the applied anti-tumor promotion experiment.The chemo-preventive effect of 3-oxo-6β-hydroxy-β-amyrin was comparable to curcumin as positive control based on the reduction of immediate early tumor antigen expression.Molecular docking by applying Autodock Vina 1 and i-GEMDOCK v 2.1 tools indicated that compound 1 gives good docking results,as determined by their fitness score and specificity.Moreover,results showed that compound 1 isolated from Pistacia integerrima precisely attached to a region where co-crystallized ligand for receptor previously existed.Our findings may explain the use of Pistacia integerrima plant extracts as an anticancer agent in folk medicine. | ABDUR RAUF SAUD BAWAZEER MUSLIM RAZA EMAN EL-SHARKAWY MD.HABIBUR RAHMAN MOHAMED A.EL-ESAWI GHIAS UDDIN BINA SSIDDIQUI ANEES AHMED KHALIL JOSEPH MOLNAR AKOS CSONKA DIÁNA SZABÓ HAROON KHAN MOHAMMAD SMUBARAK TAIBI BEN HADDA MUDYAWATI KAMARUDDIN SEEMA PATEL | 2021 | BIOCELL2021，45，1： | 0 |
| 15 | 癌生长是寄主中的过寄生现象(英文)显示文摘报道了人乳腺癌细胞MCF7和正常细胞MCF10,MRC5混合培养实验,分析了实验结果.结果表明:在营养物充足条件下癌细胞和正常细胞系寄生共存关系,而在饥饿条件下癌细胞和正常细胞是过寄生-捕食者和食饵的关系.讨论了此结果的生物医学含义. | Molnar Joseph 罗辽复 Gyemant Nora Mucsi Ilona Vezendi Klára Ocsovszki Imre Sz kefalvi-Nagy Elisabeth Thornton BarryS | 2007 | 内蒙古大学学报(自然科学版)2007，38，1： | 0 |
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