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    题名 作者 年代 出处 被引量
1利用PRECIS分析SRES B2情景下中国区域的气候变化响应显示文摘利用Hadley气候预测与研究中心的区域气候模式系统PRECIS单向嵌套该中心全球海.气耦合气候模式HadCM3高分辨率的大气部分HadAM3P,分析PRECIS对中国区域当代气候的模拟能力和SRESB2情景下2071-2100时段(2080s)相对于气候基准时段(1961~1990年)中国区域的气候变化响应.气候基准时段的模拟结果与观测资料的对比分析表明:PRECIS能够很好地模拟中国区域地面气温的局地分布特征;总体上讲,PRECIS对中国北方地区降水的模拟效果优于南方地区,模拟的冬季降水型态分布较好,而夏季降水对地形比较敏感,东南沿海地区降水的模拟值偏低.对SRESB2情景下相对于气候基准时段的气候变化响应分析表明:2080s中国北方地区增温幅度明显大于南方,西北和东北地区尤为显著,其夏季平均气温增幅可达50℃以上;中国大部分地区降水量呈增加趋势;冬季华南地区降水量明显减少;夏季东北和华北地区气温增幅大而降水量减少明显,而长江以南地区降水量显著增加.许吟隆 张勇 林一骅 林而达 林万涛 董文杰 Richard Jones David Hassell Simon Wilson 2006科学通报2006,51,17:86
2近百年中国气温变化中的不确定性估计显示文摘利用均一化的中国近百年气温观测数据,结合英国East Anglia大学气候研究中心(CRU)的CRUTEM3气温数据集中中国周边国家长序列资料对20世纪前50年资料进行了补充,研制了中国及周边地区近百年逐月5°×5°气温网格数据集,并综合系统考虑了该气温数据集中存在的3类误差(台站误差、抽样误差和偏差误差)导致的不确定性水平,重新构建了近百年全国气温变化序列,并给出了各种不确定性水平,得出了近百年中国气温变化的最新估计.基于上述数据集系统性地对中国近100年地表气温变化趋势进行了重新估计.结果显示:1900~2006年中国气温变化速度为(0.09±0.017)℃/10a;冬季最大,为(0.14±0.021)℃/10a;夏季最小为(0.04±0.017)℃/10a;春季为(0.11±0.021)℃/10a;秋季为(0.07±0.017)℃/10a.近50年(1954~2006年)气温增暖趋势约为(0.26±0.032)℃/10a,近30年(1979~2006年)增暖趋势为(0.45±0.13)℃/10a,气温增暖速率呈明显加剧趋势,值得引起注意.从地理分布上来看,东北、西北和华北地区的增暖幅度最为明显,而西南、华南地区增暖幅度最小,这种变化在近100,50和30年具有较好的一致性.李庆祥 董文杰 李伟 高小蓉 JONES Phil KENNEDY John PARKER David 2010科学通报2010,55,16:82
3Severe acute pancreatitis: pathogenesis, diagnosis and surgical management显示文摘BACKGROUND: Severe acute pancreatitis is a subtype of acute pancreatitis, associated with multiple organ failure and systemic inflammatory response syndrome. In this qualitative review we looked at the principles of pathogenesis, classification and surgical management of severe acute pancreatitis. We also looked at the current shift in paradigm in the management of severe acute pancreatitis since the guideline developed by the British Society of Gastroenterology.DATA SOURCES: Studies published between 1st January 1991 and 31st December 2015 were identified with Pub Med, MEDLINE, EMBASE and Google Scholar online search engines using the following Medical Subject Headings: 'acute pancreatitis, necrosis, mortality, pathogenesis, incidence' and the terms 'open necrosectomy and minimally invasive necrosectomy'.The National Institute of Clinical Excellence(NICE) Guidelines were also included in our study. Inclusion criteria for our clinical review included established guidelines, randomized controlled trials and non-randomized controlled trials with a follow-up duration of more than 6 weeks.RESULTS: The incidence of severe acute pancreatitis within the UK is significantly rising and pathogenetic theories are still controversial. In developed countries, the most common cause is biliary calculi. The British Society of Gastroenterology,acknowledges the Revised Atlanta criteria for prediction of severity. A newer Determinant-based system has been developed.The principle of surgical management of acute necrotizing pancreatitis requires intensive care management, identifying infection and if indicated, debridement of any infected necrotic area. The current procedures opted for include standard surgical open necrosectomy, endoscopic necrosectomy and minimally invasive necrosectomy. The current paradigm is shifting towards a step-up approach.CONCLUSIONS: Severe acute pancreatitis is still a subject of grey areas in its surgical management even though new studies have been recorded since the origin of the latest UK guidelines for management of severe acute pancreatitis.Mark Portelli Christopher David Jones 2017Hepatobiliary & Pancreatic Diseases International2017,16,2:201
4Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes显示文摘This review aims to outline the most up-to-date knowledge of pancreatic adenocarcinoma risk, diagnostics, treatment and outcomes, while identifying gaps that aim to stimulate further research in this understudied malignancy. Pancreatic adenocarcinoma is a lethal condition with a rising incidence, predicted to become the second leading cause of cancer death in some regions. It often presents at an advanced stage, which contributes to poor five-year survival rates of 2%-9%, ranking firmly last amongst all cancer sites in terms of prognostic outcomes for patients. Better understanding of the risk factors and symptoms associated with this disease is essential to inform both health professionals and the general population of potential preventive and/or early detection measures. The identification of high-risk patients who could benefit from screening to detect pre-malignant conditions such as pancreatic intraepithelial neoplasia, intraductal papillary mucinous neoplasms and mucinous cystic neoplasms is urgently required, however an acceptable screening test has yet to be identified. The management of pancreatic adenocarcinoma is evolving, with the introduction of new surgical techniques and medical therapies such as laparoscopic techniques and neo-adjuvant chemoradiotherapy, however this has only led to modest improvements in outcomes. The identification of novel biomarkers is desirable to move towards a precision medicine era, where pancreatic cancer therapy can be tailored to the individual patient, while unnecessary treatments that have negative consequences on quality of life could be prevented for others. Research efforts must also focus on the development of new agents and delivery systems. Overall, considerable progress is required to reduce the burden associated with pancreatic cancer. Recent, renewed efforts to fund large consortia and research into pancreatic adenocarcinoma are welcomed, but further streams will be necessary to facilitate the momentum needed to bring breakthroughs seen for other cancer sites.Andrew McGuigan Paul Kelly Richard C Turkington Claire Jones Helen G Coleman R Stephen McCain 2018World Journal of Gastroenterology2018,24,43:140
5藏北高原地壳及上地幔导电性结构——超宽频带大地电磁测深研究结果显示文摘为了研究西藏中、北部壳、幔导电性结构,讨论高原中、北部岩石圈热状态,1998年和1999年(INDEPTH(Ⅲ)-MT)在西藏中、北部完成了德庆—龙尾错(500线)和那曲—格尔木(600线)超宽频带大地电磁深探测剖面的研究.研究结果表明,西藏中、北部以昆仑山断裂为界,其南北壳、幔电性结构有很大差异.昆仑山断裂以北地壳和上地幔为高阻区.而昆仑山以南,地壳和上地幔的导电性有明显的分层结构:地壳上部以不连续的高阻体为主,夹有局部低阻异常体,沿南北方向上地壳的电性结构复杂,具有不连续、分块的特点;但中、下地壳为大范围的高导异常区,区内发育有大规模、不相连续、产状各异的高导体,其电阻率均小于4Ωm;在班公—怒江和金沙江缝合带之下,壳内高导体都具有向上地幔延伸的趋势,存在连通壳、幔的低阻通道.根据西藏高原中、北部壳、幔电性结构的研究推断:如同藏南一样,这里也普遍存在部分熔融体和热流体,它们的成因主要与班公—怒江和金沙江缝合带的壳-幔热交换、热活动有关,这是两期形成的壳-幔热交换通道.其中,班公—怒江缝合带的壳-幔热交换通道形成时间比金沙江缝合带早.因此,研究区壳、幔的热活动是从南边和西边开始,向北、向东扩展,导致现今西藏中、北部地壳和上地幔的热流分布由西向东、由南向北增大.魏文博 金胜 叶高峰 邓明 谭捍东 Martyn Unsworth Alan G. Jones John Booker Shenghui Li 2006地球物理学报2006,49,4:71
6婴幼儿卒中的处理:来自美国心脏协会卒中委员会和青少年心血管病委员会专门写作组的科学声明显示文摘目的:本声明旨在回顾有关儿童卒中的文献,为最佳的诊断和治疗提供推荐意见,供负责诊断和治疗婴儿、儿童和青少年脑血管病的医生使用。方法:写作组成员由美国心脏协会卒中委员会科学声明监督委员会任命,由多个不同领域的专家组成。应用美国心脏协会卒中委员会的证据分级标准对每条推荐意见进行分级。在经过小组成员审查后,草稿由4位同行评议专家和卒中委员会指导委员会成员审阅,并由美国心脏协会科学咨询和协调委员会批准。我们预计该声明需在4年内进行更新。结果:为镰状细胞病、烟雾病、颈一脑动脉夹层分离和心源性栓塞引起的缺血性卒中的预防提供循证推荐,同时为出血性卒中的评价和处理提供推荐意见。提出儿童使用肝素和华法林的剂量方案。另外,还为围产期卒中和儿童脑静脉窦血栓形成的评价和处理提供推荐。E.Steve Roach(著) Meredith R. Golomb(著) Robert Adams(著) Jose Biller(著) Stephen Daniels(著) Gabrielle deVeber(著) Donna Ferriero(著) Blaise V. Jones(著) Fenella J. Kirkham(著) R. Michael Scott(著) Edward R. Smith(著) 刘丽芳(译) 王胜男(译) 王伟(译) 林镇洲(译) 朱佳佳(译) 潘速跃(译) 2008国际脑血管病杂志2008,16,11:60
7利用ECMWF再分析数据验证PRECIS对中国区域气候的模拟能力显示文摘本文利用1979-1983年的ECMWF再分析数据作为准观测侧边界条件驱动:Hadley气候预测和研究中心的区域气候模式系统PRECIS,验证PRECIS对中国区域的气候模拟能力。选择典型的观测站点北京模拟的日最高/最低气温、太阳短波总辐射和月均降水量与观测结果进行直接比较,显示:PRECIS具有很强的模拟地面气候季节变化的能力。全国740个台站的观测与模拟值的统计分析表明:尽管模拟的最高,最低气温在0℃附近有一‘锯齿’状的偏差,PRECIS能够很好地模拟全国范围最高/最低气温的型态分布特征;从全国范围看,模拟的降水值偏高,但显示出很强的模拟极端降水事件的能力;模拟的地面太阳短波总辐射与全国122个台站的观测结果的比较显示:PRECIS模拟的辐射值偏高,全国范围内约高22%。因此,当应用PRECIS输出结果进行气候变化的影响评价时,需要对模式的输出结果进行订正。许吟隆 Richard Jones 2004中国农业气象2004,25,1:59
8西藏高原南部雅鲁藏布江缝合带地区地壳电性结构研究显示文摘为了探测西藏高原南部雅鲁藏布江缝合带地区地壳浅部和深部构造沿东西和南北方向的变化特征 ,在雅鲁藏布江缝合带地区布设了三条南北向剖面 (错那—墨竹工卡、亚东—雪古拉、吉隆—措勤 ) ,采用超宽频带大地电磁测深方法进行了地壳、上地幔电性结构探测研究 ,发现该区主要电性结构特征为 :1.雅鲁藏布江缝合带附近表层发育大规模的高阻体 ,岩体延伸最深达 30km以上 ,是冈底斯花岗岩体的反映 .2 .雅鲁藏布江缝合带的南部有小规模的良导体 ,在其下方和北侧发育有大规模良导体 .3.沿剖面从南往北壳内普遍发育良导体 ,各良导体主体间是不连续的 ,规模逐渐增大 ,总体北倾 ,在缝合带附近产状较陡 .4 .在雅鲁藏布江缝合带附近良导体由西往东规模逐渐增大 ,导电性逐渐变好 ,相对雅鲁藏布江在剖面上的位置逐渐南移 .这些重要的电性特征可能是印度板块向北俯冲所形成的 。谭捍东 魏文博 Martyn Unsworth 邓明 金胜 John Booker Alan Jones 2004地球物理学报2004,47,4:42
9藏南岩石圈导电性结构与流变性——超宽频带大地电磁测深研究结果显示文摘为了比较全面、客观地认识青藏高原岩石圈深部结构,探讨高原岩石圈形变特征、应变状态、热结构、板块(或地体)运动和壳、幔物质流变等重要科学问题,必须研究高原内部各个地质构造区域壳、幔电性结构沿东西方向的变化;INDEPTH-MT在喜马拉雅-西藏南部地区完成了6条超宽频带大地电磁深探测剖面研究.通过这6条剖面的电性结构成像,讨论了研究区地壳和上地幔导电性三维结构特点;发现西藏南部沿东西方向超出1000km范围,较普遍存在中、下地壳高导层,这高导层并不完全是连续的,向雅鲁藏布江大拐弯处高导层变薄、变浅、电阻率升高.讨论了藏南岩石圈的流变性问题,认为藏南中、下地壳具有良导电性,可以证明西藏巨厚的地壳中确实存在部分'熔融体'和'热流体',藏南巨厚的中、下地壳的物质状态是热的、软弱的、塑性的,甚至可能是'流变'的;结合岩石物理实验结果的讨论认为,与藏南大地电磁资料相适应的地壳部分熔融百分比应能达到5%~14%;对于地壳中的细晶岩来说,在这个熔融百分比下引起黏度的降低量有可能达到引起地壳'流变性'的要求;但对于花岗岩来说,也许不足以引起地壳产生'流变'.魏文博 金胜 叶高峰 邓明 景建恩 Unsworth MARTYN Jones G.ALAN 2009中国科学(D辑)2009,39,11:41
10Hydrogen Sulfide Alleviates Aluminum Toxicity in Germinating Wheat Seedlings显示文摘Protective role of hydrogen sulfide(H2S) on seed germination and seedling growth was studied in wheat(Triticum) seeds subjected to aluminum(Al3+) stress.We show that germination and seedling growth of wheat is inhibited by high concentrations of AlCl3.At 30 mmol/L AlCl3 germination is reduced by about 50% and seedling growth is more dramatically inhibited by this treatment.Pre-incubation of wheat seeds in the H2S donor NaHS alleviates AlCl3-induced stress in a dose-dependant manner at an optimal concentration of 0.3 mmol/L.We verified that the role of NaHS in alleviating Al3+ stress could be attributed to H2S/HS-by showing that the level of endogenous H2S increased following NaHS treatment.Furthermore,other sodium salts containing sulfur were ineffective in alleviating Al3+ stress.NaHS pretreatment significantly increased the activities of amylases and esterases and sustained much lower levels of MDA and H2O2 in germinating seeds under Al3+ stress.Moreover,NaHS pretreatment increased the activities of guaiacol peroxidase,ascorbate peroxidase,superoxide dismutase and catalase and decreased that of lipoxygenase.NaHS pretreatment also decreased the uptake of Al3+ in AlCl3-treated seed.Taken together these results suggest that H2S could increase antioxidant capability in wheat seeds leading to the alleviation of Al3+ stress.Hua Zhang Zhu-Qin Tan Lan-Ying Hu Song-Hua Wang Jian-Ping Luo Russell L. Jones 2010Journal of Integrative Plant Biology2010,52,6:49
11Analyses on the climate change responses over China under SRES B2 scenario using PRECIS显示文摘The PRECIS,a regional climate model system developed at the UK Met Office Hadley Cen- tre for Climate Prediction and Research,which is nested in one-way mode within the HadAM3P,a higher-resolution version of the atmospheric com- ponent of the Hadley Centre climate model HadCM3,is employed to simulate the baseline (1961—1990) climate for evaluation of model’s capacity of simu- lating present climate and analyze the future climate change responses in the time-slice of 2071—2100 (2080s) under SRES B2 scenario over China relative to baseline average. It is indicated from the com- parison of the simulated baseline climate with in situ observation that PRECIS can simulate the local dis- tribution characteristics of surface air temperature over China quite well; generally speaking,the simu- lation for precipitation in the north of China and in winter is better than in the south of China and in summer,respectively; the simulation of precipitation in summer is sensitive to topography,and the simu- lated precipitation values are lower than observations over southeast coastal areas. It is shown from the analyses on the simulated climate change responses in 2080s under SRES B2 scenario relative to base- line that there would be an obvious surface air tem- perature increase in the north of China relative to that in the south of China,and especially in Northwest China and Northeast China,the amplitude ofsummer mean surface air temperature increments could reach 5℃; there would be an overall increase of the simulated precipitation in 2080s under SRES B2 scenario over most areas of China,while there would be significant precipitation decreases in South China in winter; there would be obvious precipitation decreases in Northeast China and North China in summer with high surface air temperature increase. However,it presents an obvious precipitation in- crease over the middle and lower reaches of the Yangtze River in summer.XU Yinlong ZHANG Yong LIN Erda LIN Wantao DONG Wenjie Richard Jones David Hassell Simon Wilson 2006Chinese Science Bulletin2006,51,18:39
12青岛近海沉积物PCBs的水平与垂直分布及贝类污染显示文摘利用13C 同位素内标法及气相色谱-质谱方法对青岛胶州湾内外8个表层沉积物,1个沉积物柱状岩心和2个贝类样品中包括14种共平面PCBs在内的50种PCBs同系物含量进行了测定,在所有样品中均检测出了PCBs化合物.讨论了PCBs的分布特征.表层样品以胶州湾东岸的含量最高,从北岸、西岸、胶州湾口及胶州湾外PCBBs含量逐渐降低.表层沉积物中总PCBs含量在0.65~32.9ng/g dw.PCBs总含量落在国内外海洋近岸表层沉积物含量范围的中值区.表明污染来源有城市污水排放及大气来源2种,而不属于工业污染类型.多氯联苯主要以低氯取代PCBs为主,大部分高氯取代PCBs的含量低于检出限.柱状样中共平面PCBs的含量及毒性当量浓度总的垂直变化趋势是从1951年到现在逐渐减少.贝类样品的总PCBs含量为4.9~8.4ngg/g dw,属低污染水平.杨永亮 潘静 李悦 石磊 殷效彩 李凤业 Kevin Jones 2003中国环境科学2003,23,5:32
13功率IGBT模块的寿命预测显示文摘介绍了功率循环试验数据的威布尔分析方法,分析了现有的典型模块寿命模型,论述了寿命预测的方法:将任务曲线转化成温度曲线,利用雨流计数法,根据线性疲劳损伤积累理论和寿命模型计算功率循环寿命。最后,预测了应用于HXD1C电力机车的株洲南车时代电气股份有限公司3300V/1200A IGBT模块的功率循环寿命。王彦刚 Chamund Dinesh 李世平 Jones Steve 窦泽春 忻兰苑 刘国友 2013机车电传动2013,,2:27
14Assessment of the uncertainties in temperature change in China during the last century显示文摘We have used the China Homogenized Historic Temperature dataset and some long-term station series of the neighbor countries from CRUTEM3,a 5°×5° gridded dataset of monthly mean temperature since 1900,to provide a 107-year record of surface temperature trends and variability.We derived a comprehensive set of uncertainty estimates to accompany the data:measurement and sampling errors,uncertainties in temperature bias estimates,and uncertainties arising from limited observational coverage on large-scale averages have all been estimated.We reanalysed the temperature changes during the period of record.The best estimates of trends for 1900-2006 with uncertainties at 95% confidence range are about 0.09±0.017°C/decade for the year as a whole,and 0.14±0.021°C/decade,0.11±0.021°C/decade,0.04±0.017°C/decade,and 0.07±0.017°C/decade for winter,spring,summer and autumn respectively.For 1954-2006,the trends for annual,winter,spring,summer and autumn are:0.26±0.032°C/decade,0.35±0.046°C/decade,0.25±0.051°C/decade,0.16±0.037°C/decade and 0.22±0.055°C/decade.Winter saw the most significant warming trend in both 1900-2006 and 1954-2006,while during the most recent period(the satellite era,1979-2006),all the seasons show similar warming trends:0.45±0.13°C/decade,0.51±0.11°C/decade,0.52±0.16°C/decade,0.37±0.10°C/decade and 0.50±0.16°C/decade for annual,winter,spring,summer and autumn.Trends arising from urbanization have been evaluated as less than 5% of the total warming trend for 1951-2001,so this bias was not removed.LI QingXiang DONG WenJie LI Wei GAO XiaoRong JONES P KENNEDY J PARKER D 2010Chinese Science Bulletin2010,55,19:26
15Current practices and future prospects for the management of gallbladder polyps: A topical review显示文摘A gallbladder polyp is an elevation of the gallbladder mucosa that protrudes into the gallbladder lumen. Gallbladder polyps have an estimated prevalence in adults of between 0.3%-12.3%. However, only 5% of polyps are considered to be 'true' gallbladder polyps, meaning that they are malignant or have malignant potential. The main radiological modality used for diagnosing and surveilling gallbladder polyps is transabdominal ultrasonography. However, evidence shows that other modalities such as endoscopic ultrasound may improve diagnostic accuracy. These are discussed in turn during the course of this review. Current guidelines recommend cholecystectomy for gallbladder polyps sized 10 mm and greater, although this threshold is lowered when other risk factors are identified. The evidence behind this practice is relatively low quality. This review identifies current gaps in the available evidence and highlights the necessity for further research to enable better decision making regarding which patients should undergo cholecystectomy, and/or radiological follow-up.R Stephen McCain Anna Diamond Claire Jones Helen G Coleman 2018World Journal of Gastroenterology2018,24,26:25
16中国的炭疽杆菌DNA分型及其地理分布显示文摘炭疽广泛分布于中国各地 ,特别是西部地区 ,并经常造成人畜疾病。在一项合作研究中 ,用多位点VNTR分析 (MLVA)对从 195 2~ 1998年自中国主要地理流行区域分离的病人、病畜和土壤等来源的炭疽杆菌进行了基因分型。MLVA分析结果揭示了 2 1种新的基因型 ,其等位基因组合在以前世界范围分离物的研究中未曾发现。此外 ,分离物的分群显示 ,A3b组是地理上最广泛分布的基因组 ,说明该组可能是中国的“地方流行株”。王秉翔 SmithKL Keys C Coker P Keimp Jones M H 2002微生物学免疫学进展2002,30,1:22
17北京城区可吸入颗粒物(PM_10)的矿物学研究显示文摘使用X射线衍射技术(XRD)和扫描电镜技术(SEM/EDX)对北京PM10中的矿物组分进行了分析.结果表明,北京PM10中的矿物组分存在明显的季节变化规律,春季PM10中的矿物组成种类最多;秋季PM10中的矿物种类最少;在夏季PM10中,矿物的种类有所减少,却有新的物种出现,如NH4Cl、K(NH4)Ca(SO4)2?H2O、As2O3?SO3等.粘土矿物是北京PM10中含量最高的矿物,石英的含量次之,其他依次为方解石、石膏、长石、白云石以及其他矿物颗粒;北京PM10中还存在一定数量的复合颗粒,颗粒表面常有S、Cl元素的存在.吕森林 邵龙义 吴明红 焦正 JONES T P 2005中国环境科学2005,25,2:21
18不同埋藏深度交代白云石晶体结构及其对白云岩储层研究的意义显示文摘交代白云石化作用是除了原生沉淀外白云石的主要成因,对于不同埋藏深度的交代白云石晶体结构的研究有助于分析白云石被交代的过程及主要影响因素。选取加勒比海Cayman岛中新统Cayman组、南海中新统宣德组和四川盆地上震旦统灯影组3类保留了原岩颗粒结构的交代白云石进行研究,3类白云石均未受到陆源物质影响。研究手段为:X衍射分析成分、有序度、晶胞参数;透射电镜观察晶体微形貌特征。随着埋藏深度从几米至几百米再至几千米依次加深,晶体自形程度逐渐变差,反映了埋藏成岩作用对交代白云石自由生长具有抑制作用;白云石有序度逐渐升高,晶胞参数逐渐向理想晶胞参数值接近,反映了后期稳定的埋藏成岩作用有利于白云石向有序转化。白云石的晶形与有序度之间不具有必然联系。通过X衍射发现,Cayman组白云岩样品中含有高镁方解石(HMC)和高钙白云石(HCD)、低钙白云石(LCD),其岩石学特征和晶体结构特征反映了交代白云石的形成是从最初的高镁方解石转化为高钙的白云石,再转化为低钙的白云石,交代白云石化可以被认为是镁离子逐渐进入方解石晶格的过程。经历足够长时间的稳定演化后,逐渐向理想白云石接近。3类交代白云石的镁离子来源为海水。表生岩溶作用不仅对于交代白云石化作用具有一定的催化作用,且经历白云石化后的岩石有利于保证原有的孔隙不易被破坏,形成了良好的储集空间,有利于后期油气的保存和运移。张杰 Brian Jones 张建勇 2014中国石油勘探2014,19,3:19
19基因枪法获得优质HMW亚基基因表达的转基因小麦显示文摘为探讨利用基因工程技术进行小麦品质改良的可行性,用基因枪法对湖北省3个小麦品种鄂恩1号、鄂麦11号和鄂麦12号分别进行优质高分子量麦谷蛋白亚基(HMW-GS)基因1Ax1和1Dx5+1Dy10的转导。试验结果表明,经基因枪轰击的幼胚外植体的再生频率和转化频率明显比幼穗高;基因型间愈伤组织再生能力和转化频率的差异,直接影响着小麦转化的成功率;3个品种的幼胚发育时期与其再生频率均呈显著负相关(r=-0.93或-0.95);在可控环境条件下,花后12~14d的供试植株幼胚的转化频率最高(鄂恩1号、鄂麦11号和鄂麦12号分别为4.5%、2.9%和2%)。研究表明,鄂恩1号、鄂麦11号适龄期的幼胚试材,用等摩尔比的优势亚基基因1Dx5和1Dy10与选择标记基因以2:1摩尔比混合的沉淀物包裹金粉,经600~900psi氦气压轰击后,在含0.5mg·L-12,4-D的MS培养基中诱导愈伤、含0.1mg·L-12,4-D和5mg·L-1玉米素的R培养基中分化、3mg·L-1L-PPT选择压下继代分化筛选,可获得稳定可育的T0代转基因植株以及胚乳特异性表达的T1代转基因种子。施农农 何光源 李克秀 Jones H.D. Shewry P.R. 2005中国农业科学2005,38,5:19
20Liver alveolar echinococcosis in China: Clinical aspect with relative basic research显示文摘This paper deals with all aspects of liver alveolar echinococcosis (AE) including epidemiology, pathology, clinical manifestations, imaging examinations, diagnosis and differential diagnosis, surgical treatment and chemotherapy.The review is not only based on personal clinical experiences but also in combination with relative basic research such as proliferation and growth of alveococcus, preclinical studies of a novel compound extracted from TCM for treatment of liver AE, and molecular immunology used for specific AE diagnosis, etc.Ci-Peng Jiang McManus Don Malcolm Jones 2005World Journal of Gastroenterology2005,11,30:19
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