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7篇 您的检索式:作者名="Jonathan Fine"
    题名 作者 年代 出处 被引量
1Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis显示文摘AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to surgery.RESULTS: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P < 0.05). Patients undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P < 0.01), had less post-operative complications (12% vs 58%, P < 0.01), and shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P < 0.01).CONCLUSION: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up time to surgery should be considered.Chris N Daniak David Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale 2008World Journal of Gastroenterology2008,14,7:13
2Relatedness of the incidence decay with exponential adjustment(IDEA)model,“Farr's law”and SIR compartmental difference equation models显示文摘Mathematical models are often regarded as recent innovations in the description and analysis of infectious disease outbreaks and epidemics,but simple mathematical expressions have been in use for projection of epidemic trajectories for more than a century.We recently introduced a single equation model(the incidence decay with exponential adjustment,or IDEA model)that can be used for short-term epidemiological forecasting.In the mid-19th century,Dr.William Farr made the observation that epidemic events rise and fall in a roughly symmetrical pattern that can be approximated by a bell-shaped curve.He noticed that this time-evolution behavior could be captured by a single mathematical formula(“Farr's law”)that could be used for epidemic forecasting.We show here that the IDEA model follows Farr's law,and show that for intuitive assumptions,Farr's Law can be derived from the IDEA model.Moreover,we show that both mathematical approaches,Farr's Law and the IDEA model,resemble solutions of a susceptible-infectious-removed(SIR)compartmental differential-equation model in an asymptotic limit,where the changes of disease transmission respond to control measures,and not only to the depletion of susceptible individuals.This suggests that the concept of the reproduction number eR 0T was implicitly captured in Farr's(pre-microbial era)work,and also suggests that control of epidemics,whether via behavior change or intervention,is as integral to the natural history of epidemics as is the dynamics of disease transmission.Mauricio Santillana Ashleigh Tuite Tahmina Nasserie Paul Fine David Champredon Leonid Chindelevitch Jonathan Dushoff David Fisman 2018Infectious Disease Modelling2018,3,1:1
3Conscious or unconscious:The impact of sedation choice on colon adenoma detection显示文摘AIM: To determine if anesthesiologist-monitored useof propofol results in improved detection of adenomaswhen compared with routine conscious sedation. METHODS: This retrospective study was conductedat two separate hospital-based endoscopy units whereapproximately 12 000 endoscopic procedures are permed annually, with one endoscopy unit exclusivelyusing anesthesiologist-monitored propofol. Three thousand two hundred and fifty-two patients underwent initial screening or surveillance colonoscopies. Our primaryend point was the adenoma detection rate, def ined asthe number of patients in whom at least one adenomawas found, associated with the type of sedation. RESULTS: Three thousand two hundred and fi ftytwooutpatient colonoscopies were performed by fi ve selected endoscopists. At least one adenoma was detected in 27.6% of patients (95% CI = 26.0-29.1) with no difference in the detection rate between the anesthes-ologist propofol and group and the gastroenterologist-midazolam/fentanyl group (28.1% vs 27.1%, P = 0.53). CONCLUSION: The type of sedation used during colonoscopy does not affect the number of patients in whom adenomatous polyps are detected.Mark Metwally Nicholas Agresti William B Hale Victor Ciofoaia Ryan O'Connor Michael B Wallace Jonathan Fine Yun Wang Seth A Gross 2011World Journal of Gastroenterology2011,17,34:1
4Renal Carcinoid Tumor: A Clinicopathologic Study of 21 Cases显示文摘Donna E. Hansel Jonathan I. Epstein Ema Berbescu Samson W. Fine Robert H. Young John C. Cheville 2007The American Journal of Surgical Pathology2007,,10:1
5Associations Between Initial Antimicrobial Therapy and Medical Outcomes for Hospitalized Elderly Patients With Pneumonia显示文摘Patrick P Gleason Thomas P Meehan Jonathan M Fine 1999Arch Intern Med1999,159,:1
6Renal Carcinoid Tumor: A Clinicopathologic Study of 21 Cases显示文摘Donna E. Hansel Jonathan I. Epstein Ema Berbescu Samson W. Fine Robert H. Young John C. Cheville 2007The American Journal of Surgical Pathology2007,,:1
7下方玻璃体腔注射后眼内炎高发病率研究(英文)显示文摘目的:探讨下方玻璃体腔注射比上方注射出现注射后眼内炎的几率是否更高。下方小梁切除术滤过泡眼内炎的发病率高于上方小梁切除术滤过泡,有可能是因为细菌聚集在下方的泪湖。方法:经过广泛实践过的眼内炎病例数据库验证,发现在2a的研究期间内,有5例眼内炎病例。同时,为了评估注射部位对发病率的影响,对治疗过的909例1 121眼共计8672次注射进行了回顾性调查。结果:5眼出现感染性眼内炎,80%的眼内炎病例均是下方注射,尽管所选病例中84.6%是位于上方注射。与感染有关的下方注射部位的危险比是(OR)22.1(P=0.006)。结论:玻璃体腔注射后感染眼内炎的几率很小,仅为0.025%。避免在偏下象限进行玻璃体腔注射可能会进一步减小眼内炎的发病率。Gowtham Jonna Daniel B. Roth Howard F. Fine H. Matthew Wheatley Jonathan L. Prenner Arvin Kheterpal Suzanne Cohen William J. Feuer 2015国际眼科杂志2015,15,5:0
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