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| 1 | Crustal structure in Xiaojiang fault zone and its vicinity显示文摘Based on the integrative interpretation of travel-time data and amplitude information obtained from the deep seismic sounding experiment on the Chuxiong-Luoping profile,eastern Yunnan province,carried out in January of 2005,we present a 2-D P wave velocity structure along the profile. The crustal structure shows remarkable contrasts between the two sides of the Xiaojiang fault zone,although the whole profile is situated within the Yangtze platform. The average P wave velocities of the crust on the west and east sides of the fault zone are 6.21 km/s and 6.32 km/s,respectively,and the crustal thicknesses are 41 km and 45 km,respectively. These results imply that the crust to the east of the Xiaojiang fault zone presents characteristics of crustal structure in a stable platform,while the crust to the west is complicated with a lower velocity zone in middle of the upper crust. The average velocity of 6.21 km/s is lower than the global continental crustal average (6.30 km/s),indicating that the region is tectonically active. According to the lateral variation of velocity and depth of interfaces (including the Moho),it is inferred that the Xiaojiang fault zone has cut through the whole crust. It is also deduced that existence of low velocity zone in middle of the upper crust is conducive to the south-southeastern sliding of the SichuanYunnan (Chuan-Dian) rhombus block. | Chunyong Wang Hai Lou Xili Wang Jiazheng Qin Runhai Yang Jinming Zhao | 2009 | Earthquake Science2009，22，4： | 14 |
| 2 | Fuzzy energy management strategy for parallel HEV based on pigeon-inspired optimization algorithm显示文摘Improvements in fuel consumption and emissions of hybrid electric vehicle(HEV)heavily depend upon an efficient energy management strategy(EMS).This paper presents an optimizing fuzzy control strategy of parallel hybrid electric vehicle em- | PEI JiaZheng SU YiXin ZHANG DanHong | 2017 | Science China(Technological Sciences)2017，60，3： | 13 |
| 3 | Independent continuous mapping for topological optimization of frame structures显示文摘基于独立连续印射方法(ICM ) ,有连续拓扑的变量的一个拓扑的优化模型被为元素重量介绍三过滤器功能造,元素许可的压力和元素僵硬,哪个变换 0-1 类型分离拓扑的变量进在 0 和 1 之间的连续拓扑的变量。为过滤器功能的二个方法被采用避免结构的奇特并且恢复虚伪地删除的元素:弱材料元素方法和微小的节元素方法。三个标准(没有结构的奇特,没有违背的限制和结构的重量的没有变化) 被介绍判定重复集中。这些标准允许由在重复过程调整一个折扣因素发现适当阀值。改进效率,原来的优化模型根据双理论被转变成一个双问题并且在它的双空间解决了。由作为发展中的平台把 MSC/Nastran 用作结构的解答者和 MSC/Patran,框架结构的一个拓扑的优化软件被完成。数字例子证明 ICM 方法为框架结构的拓扑的优化是很有效的。 | Yunkang Sui Jiazheng Du Yingqiao Guo | 2006 | Acta Mechanica Sinica2006，22，6： | 10 |
| 4 | Activation of liver X receptors promotes inflammatory cytokine mRNA degradation by upregulation of tristetraprolin显示文摘肝 X 受体(LXR ) 有反煽动性的性质。LXR 是否在煽动性的 cytokine 表示的 post-transcriptional 控制起一个作用,不是清楚的。这里,我们第一鉴别合成 LXR 收缩筋 T0901317 支持了 IL-1, IL-6 和 TNF mRNA 降级。而且, T0901317 使动摇通过它的 3-untranslated 区域的 TNF mRNA。另外, T0901317 增加了 tristetraprolin (TTP ) 的表示,当与 siRNA 反对 TTP 废除了调停 T0901317 的煽动性的 cytokine mRNA 腐烂时。有趣地, T0901317 镇压了 ERK1/2 和 p38 的导致 LPS 的 phosphorylation 在 THP-1 巨噬细胞的激活 mitogen 的蛋白质 kinase (MAPK ) 。这里介绍的证据证实有 T0901317 的 LXR 激活禁止 ERK1/2 和 p38 MAPK 的 phosphorylation,在 TTP 的增加的表示和 LPS 导致煽动性的 cytokine mRNAs 的腐烂的可能的结果。 | Ji Xiao Quan Chen Dan Tang Weiwei OU Jiazheng Wang1 Zhongcheng Mo Chaoke Tang Liangyu Peng Deming Wang | 2017 | Acta Biochimica et Biophysica Sinica2017，49，3： | 7 |
| 5 | An App knock-in rat model for Alzheimer’s disease exhibiting Aβand tau pathologies,neuronal death and cognitive impairments显示文摘A major obstacle in Alzheimer’s disease(AD)research is the lack of predictive and translatable animal models that reflect disease progression and drug efficacy.Transgenic mice overexpressing amyloid precursor protein(App)gene manifest non-physiological and ectopic expression of APP and its fragments in the brain,which is not observed in AD patients.The App knock-in mice circumvented some of these problems,but they do not exhibit tau pathology and neuronal death.We have generated a rat model,with three familiar App mutations and humanized Aβsequence knocked into the rat App gene.Without altering the levels of full-length APP and other APP fragments,this model exhibits pathologies and disease progression resembling those in human patients:deposit of Aβplaques in relevant brain regions,microglia activation and gliosis,progressive synaptic degeneration and AD-relevant cognitive deficits.Interestingly,we have observed tau pathology,neuronal apoptosis and necroptosis and brain atrophy,phenotypes rarely seen in other APP models.This App knock-in rat model may serve as a useful tool for AD research,identifying new drug targets and biomarkers,and testing therapeutics. | Keliang Pang Richeng Jiang Wei Zhang Zhengyi Yang Lin-Lin Li Makoto Shimozawa Simone Tambaro Johanna Mayer Baogui Zhang Man Li Jiesi Wang Hang Liu Ailing Yang Xi Chen Jiazheng Liu Bengt Winblad Hua Han Tianzi Jiang Weiwen Wang Per Nilsson Wei Guo Bai Lu | 2022 | Cell Research2022，32，2： | 6 |
| 6 | Velocity forecasts using a combined deep learning model in hybrid electric vehicles with V2V and V2I communication显示文摘Vehicle velocity forecast is an important clue in improving the performance of energy management in hybrid electric vehicles(HEV). This paper presents a new combined model for predicting vehicle’s velocity time series. The main features of the model are to combine the feature extraction capability of deep restricted Boltzmann machines(DBM) and sequence pattern predicting capability of bidirectional long short-term memory(BLSTM). Hence, the model is named as DBMBLSTM. In addition, the DRMBLSTM model utilizes the vehicle driving information and roadside infrastructure information provided respectively through vehicle-to-vehicle(V2V) and vehicle-to-infrastructure(V2I) communication channels to predict vehicle velocity at various length of prediction horizon. Furthermore, the predictions results of this study are compared with the state of the art of vehicle velocity forecasts. The root mean square error(RMSE) is used as an evaluation criteria of predictions accuracy. Finally,these compared prediction model are applied in model predictive control(MPC) energy management strategy for the verifications of fuel economy improvement of a HEV. Simulation results confirm that the proposed combined deep learning model performs better than other five prediction methods. Therefore, it is a means of arriving at a reliable forecast model for HEV. | PEI JiaZheng SU YiXin ZHANG DanHong QI Yue LENG ZhiWen | 2020 | Science China(Technological Sciences)2020，63，1： | 6 |
| 7 | Seismic phases from the Moho and its implication on the ultraslow spreading ridge显示文摘The Moho interface provides critical evidence for crustal thickness and the mode of oceanic crust accretion.The seismic Moho interface has not been identified yet at the magma-rich segments(46°–52°E)of the ultraslow spreading Southwestern Indian Ridge(SWIR).This paper firstly deduces the characteristics and domains of seismic phases based on a theoretical oceanic crust model.Then,topographic correction is carried out for the OBS record sections along Profile Y3Y4 using the latest OBS data acquired from the detailed 3D seismic survey at the SWIR in 2010.Seismic phases are identified and analyzed,especially for the reflected and refracted seismic phases from the Moho.A 2D crustal model is finally established using the ray tracing and travel-time simulation method.The presence of reflected seismic phases at Segment 28 shows that the crustal rocks have been separated from the mantle by cooling and the Moho interface has already formed at zero age.The 2D seismic velocity structure across the axis of Segment 28 indicates that detachment faults play a key role during the processes of asymmetric oceanic crust accretion. | ZHANG Jiazheng ZHAO Minghui QIU Xuelin LI Jiabiao RUAN Aiguo | 2013 | Acta Oceanologica Sinica2013，32，12： | 5 |
| 8 | Ternary mesoporous cobalt-iron-nickel oxide efficiently catalyzing oxygen/hydrogen evolution reactions and overall water splitting显示文摘Among various efficient electrocatalysts for water splitting,CoFe and NiFe-based oxides/hydroxides are typically promising candidates thanks to their extraordinary activities towards oxygen evolution reaction (OER).However,the endeavor to advance their performance towards overall water splitting has been largely impeded by the limited activities for hydrogen evolution reaction (HER).Herein,we present a CoFeNi ternary metal-based oxide (CoFeNi-O) with impressive hierarchical bimodal channel nanostructures,which was synthesized via a facile one-step dealloying strategy.The oxide shows superior catalytic activities towards both HER and OER in alkaline solution due to the alloying effect and the intrinsic hierarchical porous structure.CoFeNi-O loaded on glass carbon electrodes only requires the overpotentials as low as 230 and 278 mV to achieve the OER current densities of 10 and 100 mA·cm-2,respectively.In particular,extremely low overpotentials of 200 and 57.9 mV are sufficient enough for Ni foam-supported CoFeNi-O to drive the current density of 10 mA·cm-2 towards OER and HER respectively,which is comparable with or even better than the already-developed state-of-the-art non-noble metal oxide based catalysts.Benefiting from the bifunctionalities of CoFeNi-O,an alkaline electrolyzer constructed by the Ni foam-supported CoFeNi-O electrodes as both the anode and the cathode can deliver a current density of 10 mA·cm-2 at a fairly low cell-voltage of 1.558 V.In view of its electrocatalytic merits together with the facile and cost-effective dealloying route,CoFeNi-O is envisioned as a promising catalyst for future production of sustainable energy resources. | Lulu Han Limin Guo Chaoqun Dong Chi Zhang Hui Gao Jiazheng Niu Zhangquan Peng Zhonghua Zhang | 2019 | Nano Research2019，12，9： | 5 |
| 9 | Strong Earthquake Activity and Its Relation to Regional Neotectonic Movement in Sichuan-Yunnan Region显示文摘Based on analyzing space inhomogeneous image of strong earthquake activity, the image of source rupture and the mechanical property of the source fault in Sichuan-Yunnan region, the relations among the strong earthquake activity, active fault, modern movement status of active blocks and structural background of the deep media have been discussed, and the characteristics of strong earthquake activity and possible mechanism have been also discussed. | Su Youjin and Qin Jiazheng Seismological Bureau of Yunnan Province,Kunming 650041,China | 2001 | Earthquake Research in China2001，15，3： | 4 |
| 10 | MEF2C promotes M1 macrophage polarization and Th1 responses显示文摘The polarization of macrophages to the M1 or M2 phenotype has a pivotal role in inflammation and host defense;however,the underlying molecular mechanism remains unclear.Here,we show that myocyte enhancer factor 2 C(MEF2C)is essential for regulating M1 macrophage polarization in response to infection and inflammation.Global gene expression analysis demonstrated that MEF2C deficiency in macrophages downregulated the expression of M1 phenotypic markers and upregulated the expression of M2 phenotypic markers.MEF2C significantly promoted the expression of interleukin-12 p35 subunit(Il12a)and interleukin-12 p40 subunit(Il12b).Myeloid-specific Mef2c-knockout mice showed reduced IL-12 production and impaired Th1 responses,which led to susceptibility to Listeria monocytogenes infection and protected against DSS-induced IBD in vivo.Mechanistically,we showed that MEF2C directly activated the transcription of Il12a and Il12b.These findings reveal a new function of MEF2C in macrophage polarization and Th1 responses and identify MEF2C as a potential target for therapeutic intervention in inflammatory and autoimmune diseases. | Xibao Zhao Qianqian Di Han Liu Jiazheng Quan Jing Ling Zizhao Zhao Yue Xiao Han Wu Zherui Wu Wengang Song Huazhang An Weilin Chen | 2022 | Cellular & Molecular Immunology2022，19，4： | 4 |
| 11 | Experimental investigation on active acoustic flutter control显示文摘Experimenial studies on active acoustic fiutter control are carried out successfully in wind-tunnel after the theoretical study The experdrients verify the theory presented in the reference[1] and give valuable experimeotal results which predict a prondsing future of applying new techology and new ideas to the area of vibration induced by flow. | YANG Jun(Institute of Acoustics, Academic Sinica Beijing 100080)(State Key Lab. of Modern Acoustics, Naniing Universitg Naning 210093)HAN Fei QIU Xiaojun and SHA Jiazheng(State Key Lab. of Modern Acoustics, Nanjing Universitg Naning 210093) | 1997 | Chinese Journal of Acoustics1997，16，1： | 3 |
| 12 | Topology optimization of continuum structures considering damage based on independent continuous mapping method显示文摘A continuum topology optimization usually produces results similar to a skeleton structure. In addition, the material utilization in the optimized structure is greatly improved compared with the original structure. On the other hand, the redundancy of the structure is greatly reduced due to the removed material. A partial local failure in the optimized structure makes it more difficult for the entire structure to meet the strength/stiffness requirements. By using the independent continuous mapping (ICM) method, with minimal weight as the objective and both stress and displacement as the respective constraints, the continuum topology optimization models can be employed, which also consider damage. A dual-sequence quadratic programming (DSQP) algorithm is used to solve the topology optimization models. Numerical examples confirm the effectiveness and feasibility of the models. The results indicate that both a good load-path and weight reduction can be obtained. In addition, compared with the structure obtained using conventional topology optimization, redundancy is improved greatly, and the strength/stiffness requirements for the structure can be satisfied for each damage scenario. Furthermore, the results indicate that the strength/stiffness of the structure, after topology optimization, is slightly sensitive for local damage. | Jiazheng Du Yunhang Guo Zuming Chen Yunkang Sui | 2019 | Acta Mechanica Sinica2019，35，2： | 3 |
| 13 | Meridional movement of northern and southern equatorial ionization anomaly crests in the East-Asian sector during 2002-2003SSW显示文摘The present paper investigates the asymmetrical variability of the location of the north and the south equatorial ionization anomaly(EIA) crests in the East-Asian sector,along with their association with simultaneous observations of equatorial electrojet(EEJ) strength,geomagnetic activity index,and solar flux index during the 2002-2003 sudden stratospheric wanning(SSW) event.Analysis of these observations indicates the existence of a large-scale quasi 16-day periodic meridional movement in both EIA crests,and also reveals a strong correlation between the quasi 16-day oscillation in geomagnetic latitudes of the EIA crest and EEJ strength.The latitude of the northern/southern EIA crest and the EEJ strength indicate that obvious synchronous periodic oscillations were in-phase in the northern and southern hemisphere when the SSW occurred.In addition,it is also found that both the EIA crest location and amplitude of the periodic movement of the EIA locations exhibit hemispheric asymmetry.The amplitude of the periodic movement of the EIA location in the southern hemisphere is larger than that of the northern hemisphere,and the southern EIA crest is further off from the equator than the north one.Understanding these asymmetries requires a combination of mechanisms that involve at least trans-equator meridional winds and the position of a sub-solar point;however,potential disturbances in neutral winds associated with the SSW may additionally complicate the equatorial ionospheric dynamics. | MO XiaoHua ZHANG DongHe Larisa GONCHARENKO ZHANG ShunRong HAO YongQiang XIAO Zuo PEI JiaZheng Akimasa YOSHIKAWA CHAU HaDuyen | 2017 | Science China Earth Sciences2017，60，4： | 3 |
| 14 | Artificial intelligence in gastric cancer:applications and challenges显示文摘Gastric cancer(GC)is one of the most common malignant tumors with high mortality.Accurate diagnosis and treatment decisions for GC rely heavily on human experts’careful judgments on medical images.However,the improvement of the accuracy is hindered by imaging conditions,limited experience,objective criteria,and inter-observer discrepancies.Recently,the developments of machine learning,especially deep-learning algorithms,have been facilitating computers to extract more information from data automatically.Researchers are exploring the far-reaching applications of artificial intelligence(AI)in various clinical practices,including GC.Herein,we aim to provide a broad framework to summarize current research on AI in GC.In the screening of GC,AI can identify precancerous diseases and assist in early cancer detection with endoscopic examination and pathological confirmation.In the diagnosis of GC,AI can support tumor-node-metastasis(TNM)staging and subtype classification.For treatment decisions,AI can help with surgical margin determination and prognosis prediction.Meanwhile,current approaches are challenged by data scarcity and poor interpretability.To tackle these problems,more regulated data,unified processing procedures,and advanced algorithms are urgently needed to build more accurate and robust AI models for GC. | Runnan Cao Lei Tang Mengjie Fang Lianzhen Zhong Siwen Wang Lixin Gong Jiazheng Li Di Dong Jie Tian | 2022 | Gastroenterology Report2022，10，1： | 3 |
| 15 | GrabCut image segmentation algorithm based on structure tensor显示文摘This paper attempts to present an interactive color natural images segmentation method. This method extracts the feature of images by using the nonlinear compact structure tensor(NCST) and then uses GrabCut method to obtain the segmentation. This method not only realizes the non-parametric fusion of texture information and color information, but also improves the efficiency of the calculation. Then, the improved GrabCut algorithm is used to evaluate the foreground target segmentation. In order to calculate the simplicity and efficiency, this paper also extends the Gaussian mixture model(GMM) constructed base on the GrabC ut to the tensor space, and uses the Kullback-Leibler(KL) divergence instead of the usual Riemannian geometry. Lastly, an iteration convergence criterion is proposed to reduce the time of the iteration of GrabCut algorithm dramatically with satisfied segmentation accuracy. After conducting a large number of experiments on synthetic texture images and natural images, the results demonstrate that this method has a more accurate segmentation effect. | Zhang Yong Yuan Jiazheng Liu Hongzhe Li Qing | 2017 | The Journal of China Universities of Posts and Telecommunications2017，24，2： | 3 |
| 16 | Operando X-ray diffraction analysis of the degradation mechanisms of a spinel LiMn2O4 cathode in different voltage windows显示文摘The understanding of reaction mechanisms of electrode materials is of significant importance for the development of advanced batteries.The LiMn2O4 cathode has a voltage plateau around 2.8 V(vs.Li^+/Li),which can provide an additional capacity for Li storage,but it suffers from a severe capacity degradation.In this study,operando X-ray diffraction is carried out to investigate the structural evolutions and degradation mechanisms of LiMn2O4 in different voltage ranges.In the range of 3.0-4.3 V(vs.Li^+/Li),the LiMn2O4 cathode exhibits a low capacity but good cycling stability with cycles up to 100 cycles and the charge/discharge processes are associated with the reversible extraction/insertion of Li^+from/into LixMn2O4(0≤x≤1).In the range of 1.4-4.4 V(vs.Li^+/Li),a capacity higher than 200 mAh/g is achieved,but it rapidly decays during the cycling.The voltage plateau around 2.8 V(vs.Li^+/Li)is related to the transformation of the cubic LiMn2O4 phase to the tetragonal Li2Mn2O4 phase,which leads to the formation of cracks as well as the performance degradation. | Fakui Luo Congcong Wei Chi Zhang Hui Gao Jiazheng Niu Wensheng Ma Zhangquan Peng Yanwen Bai Zhonghua Zhang | 2020 | Journal of Energy Chemistry2020，29，5： | 2 |
| 17 | Undrained vane shear strength of sand-foam mixtures subjected to different shear rates显示文摘The shear strength of sand-foam mixtures plays a crucial role in ensuring successful earth pressure balance(EPB)shield tunneling.Since the sand-foam mixtures are constantly sheared by the cutterhead and the screw conveyor with varied rotation speeds during tunneling,it is non-trivial to investigate the effect of shear rates on the undrained shear strength of sand-foam mixtures under chamber pressures to extend the understanding on the tunneling process.This study conducted a series of pressurized vane shear tests to investigate the role of shear rates on the peak and residual strengths of sand-foam mixtures at different pore states.Different from the shear-rate characteristics of natural sands or clay,the results showed that the peak strength of sand-foam mixtures under high vertical total stress(σ_(v)≥200 kPa)and low foam injection ratio(FIR30%)decreased with the increase in shear rate.Otherwise,the peak strength was not measurably affected by shear rates.The sand-foam mixtures in the residual state resembled low-viscous fluid with yield stress and the residual strength increased slightly with shear rates.In addition,the peak and residual strengths were approximately linear with vertical effective stress regardless of the total stress and FIR.The peak effective internal friction angle remained almost invariant in a low shear rate(γ′<0.25 s1)but decreased when the shear rate continued increasing.The residual effective internal friction angle was lower than the peak counterpart and insensitive to shear rates.This study unveiled the role of shear rates in the undrained shear strength of sand-foam mixtures with various FIRs and vertical total stresses.The findings can extend the understanding of the rate-dependent shear characteristics of conditioned soils and guide the decision-making of soil conditioning schemes in the EPB shield tunneling practice. | Jiazheng Zhong Shuying Wang Tongming Qu | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023，15，6： | 2 |
| 18 | Three-dimensional ATUM-SEM reconstruction and analysis of hepatic endoplasmic reticulum-organelle interactions显示文摘The endoplasmic reticulum(ER)is a contiguous and complicated membrane network in eukaryotic cells,and membrane contact sites(MCSs)between the ER and other organelles perform vital cellular functions,including lipid homeostasis,metabolite exchange,calcium level regulation,and organelle division.Here,we establish a whole pipeline to reconstruct all ER,mitochondria,lipid droplets,lysosomes,peroxisomes,and nuclei by automated tape-collecting ultramicrotome scanning electron microscopy and deep learning techniques,which generates an unprecedented 3D model for mapping liver samples.Furthermore,the morphology of various organelles and the MCSs between the ER and other organelles are systematically analyzed.We found that the ER presents with predominantly flat cisternae and is knitted tightly all throughout the intracellular space and around other organelles.In addition,the ER has a smaller volume-to-membrane surface area ratio than other organelles,which suggests that the ER could be more suited for functions that require a large membrane surface area.Our data also indicate that ER-mitochondria contacts are particularly abundant,especially for branched mitochondria.Our study provides 3D reconstructions of various organelles in liver samples together with important fundamental information for biochemical and functional studies in the liver. | Yi Jiang Linlin Li Xi Chen Jiazheng Liu Jingbin Yuan Qiwei Xie Hua Han | 2021 | Journal of Molecular Cell Biology2021，13，9： | 2 |
| 19 | Order-Aligned Mn3O4Nanostructures as Super High-Rate Electrodes for Rechargeable Lithium-Ion Batteries显示文摘 | Wang Jiazheng Du Ning Wu Hao | 2013 | Journal of Power Sources2013，222，15： | 1 |
| 20 | Structured method for XML-based SVG显示文摘 | Jiazheng Yuan De Xu hong Sheng Hong Bao | 2007 | Journal of Computational Information System2007，3，2： | 1 |
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