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您的检索式：作者名="Jerry L.Workman"
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| 1 | Histone lysine de-β-hydroxybutyrylation by SIRT3显示文摘Recent studies have demonstrated the addition and removal of a smorgasbord of site-specific acylation modifications on lysine residues of histone tails.The study by Zhang et al. now shows how the SIRT3 histone deacylase exhibits class specificity, acting on only a subset of p-hydroxybutyrylated lysines. Modification of histones by acetylation was discovered more than half a century ago. Studies in the intervening decades have uncovered the histone acetyltransferases (HATs) responsible for this modification and the protein complexes in which these enzymes are embedded (reviewed in1). | Susan M. Abmayr Jerry L.Workman | 2019 | Cell Research2019，29，9： | 1 |
| 2 | MOCS2 links nucleotide metabolism to nucleoli function显示文摘Dear Editor,Three polyamines,putrescine,spermidine,and spermine,are tightly regulated and are synthesized from arginine,ornithine,and methionine(Miller-Fleming et al.,2015;Figure 1A).Polyamine levels are increased in the red blood cells of amyotrophic lateral sclerosis and Parkinson’s disease(PD)patients(Miller-Fleming et al.,2015).Sulfur amino acid catabolism regulated by the molybdopterin synthase associating complex prevents onset of early events in PD and Alzheimer’s disease(Suganuma et al.,2018).MPT synthase,a heterodimer of MOCS2A and MOCS2B encoded by MOCS2,is essential for the biosynthesis of molybdenum cofactor(Moco). | Tamaki Suganuma Selene K.Swanson Madelaine Gogol Timothy J.Garrett Laurence Florens Jerry L.Workman | 2021 | Journal of Molecular Cell Biology2021，13，11： | 0 |
| 3 | Reading and Interpreting the Histone Acylation Code显示文摘Decades of research has explored the epigenetic control of gene expression and the impact of histone post-translational modifications(PTMs),such as acetylation,on chromatin remodeling.Indeed,the writers,readers,and erasers of lysine acetylation are increasingly well understood.Recent studies have added crotonylation,butyrylation,and | Jelly H.M.Soffers Xuanying Li Susan M.Abmayr Jerry L.Workman | 2016 | Genomics, Proteomics & Bioinformatics2016，14，6： | 0 |
| 4 | Rpd3S meets the nucleosome显示文摘Two recent reports in Cell Research present cryo-electron microscopy structures of the Rpd3S HDAC complex bound to the nucleosome.These structures provide novel insight into the binding properties of the Rpd3S subunits Sin3,Rco1 and Eaf3 to DNA and Rco1 and Eaf3 to unmodified H3K4 and methylated H3K36,respectively,and also provide a fascinat-ing look at the unique properties of Rpd3 in recognizing specific acetylated lysines for deacetylation in the context of Rpd3S. | Michael J.Carrozza Jerry L.Workman | 2024 | Cell Research2024，34，1： | 0 |
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