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| 1 | Actions of human telomerase beyond telomeres显示文摘Telomerase 由维持 telomere 动态平衡和正直在绕过细胞的老化并且在癌症前进有基本角色。然而,最近的研究导致了一些调查者在没有它的很好确定的功能的明显的参与,在 telomere 维护表明小径的几个必要房间建议 telomerase 的新奇生物化学的性质。这些观察可以进一步在老化和癌症提高我们 telomerase 的分子的行动的理解。这评论将在 apoptosis 在 telomerase 的课外活动提供更改, DNA 修理,干细胞功能,并且在基因表示的规定。 | Yusheng Cong Jerry W Shay | 2008 | Cell Research2008,18,7: | 36 |
| 2 | 闽语词汇的时代层次(英文)显示文摘语言里往往有读音不同而来源相同的词,譬如英文的shirt和skirt都可以追溯到同一个古日耳曼语的词根;只是前者为固有的盎格鲁撒克逊语,后者却是从与古英语很相近的一种古斯堪的纳维亚方言借来的。许多语言的词汇是这样分层次的;研究语言的历史演变,辨别这种词汇层次(lexical stratification)极其重要。汉语方言里类似的现象也很普遍。北京话有不少又读字:薄bao/bo,落lao/luo,熟Shou//shu,模mu/mo,更jing/geng,等等。这些字的又读都和上述英文例子一样:前者是北京方言固有的,而后者可视为外来的借词。这种词汇层次起因于方言受某一时代共同语或标准语的影响。在中国历史上方言不断吸收共同语的成份。在华南这种情形特别地普遍而复杂。汉族多次南迁。每次都带着某种汉语方言。秦汉时,汉人第一次涌进南方,与当地土著民族杂居。关于这些早期移民的语言,我们知道得很少,据《史记》记载,多半是犯逃亡罪的人、赘婿及小商,可以推测他们的语言是当代民间通用的共同汉语。南方方言,尤其是闽语方言,还保存着这个语言的遗迹。秦汉以后,汉族第二次大规模地迁移南方是在西晋灭亡的时候(公元316年),那时大量的北方士族移居江南,南朝的首都建菜就变成中国的文化中心。因为建业的文化声望远播四方,其语言对中国南方各地方言有相当大的影响,有时甚至于代替了当地方言。陆法言的《切韵》编于陈朝灭亡后不久,据周祖谟先生研究的结果,建业和邺下的雅言对《切韵》音系的影响很大。唐代的共同语大概以长安方言为基础,与《切韵》音系颇有出入。这个方言对当时各地方言的影响非常大。到辽金元三代,北京话就成为中国的新共同语,即所谓的“官话”。中国各地方言虽然也吸收了许多“官话”的成份,但其影响力不如上面所提的那些共同语那么广泛。闽语地区比较偏僻,受其他外来影响较少,至今还保存了不少秦汉时移民带来的词汇,同时也吸收了许多南朝和唐代的词汇。因此间语里同一个汉语词根,因为历史来源不一,往往有不同的读音。这就是词汇的时代层次的宝贵证据。厦门话里这类同源词特别多:譬如《切韵》昔韵的字时常有两三个或更多的读法。我认为这些“又读字”是由不同时代遗留下来的:最早的可以推测是汉代移民所说的汉语方言的遗迹;还有些是从南朝的雅言借来的;较新的就是唐朝中叶以后借的。比方说厦门话“石”字有三个读法;最老的是[tisio?~8],就是石头的意思;第二个读法是[sia?~8],用于石砚[sia?~8hi^6];第三个读法[sik^8]是一般的文言音。福州话有相同的现象:“悬”字读[kei?~2]是高的意思;读[hei?~2]用于悬落来[hei?~2 lo?~8 li^2],是下垂的意思;读[hie?~2]用于悬空[hie?~2 khu?~1]。[kein?~2,hei?~2,hie?~2]三个音都是从一个“悬”字演变下来的,反映出三个不同时代的层次。这样,闽语方言大体上可以分成三个重要的时代层次。闽语里也许有一些词不能归到这三个层次中,可以视为例外。一般说来,中国南方方言的词汇几乎都能追溯到上述的时代。这个现象不仅汉语方言里有,中国边缘上的和国内的非汉语也都吸收了大量的汉语措词,这些借词也可以追溯到不同的历史时代。譬如越南语“墓”字有三个音:ma,mo,mo,这三个读法正相当于上述三个层次。日本语也有类似的情形:所谓上古音(Joko-on)相当于第一个层次,吴音(Go-on)相当于第二个层次,而汉音(Kanon)乃是第三个层次。泰语、朝鲜语和苗瑶语都具有大量的汉语借词;这些语言是否也有这类层次现象,有待进一步研究。 | JERRY NORMAN | 1979 | 方言1979,1,4: | 30 |
| 3 | 视网膜母细胞瘤的治疗进展显示文摘当前对视网膜母细胞瘤 (RB)的治疗方法包括化学减容法 (chemoreduction)、经瞳孔温热疗法 (TTT)、冷冻疗法、激光光凝、巩膜敷贴放射治疗、外照射放射治疗、眼球摘除、眶内容剜除和全身化学治疗。近年来 ,对于单眼为 Reese- Ellsworth V级肿瘤的患者行眼球摘除术、I~ IV级的患眼则采用化学减容法或局部治疗方法 ;对于大部分双眼 RB患者采用化学减容治疗 ,而对双眼病变程度极不对称的病例 ,在摘除高度进展患眼后 ,肿瘤较小的对侧眼常采用保守的局部治疗。 | Carol L.Shields 孙红 张军军 Jerry A.Shields | 2004 | 中华眼底病杂志2004,20,3: | 23 |
| 4 | Readers of histone modifications显示文摘在调整染色质的重要角色组织的不仅玩和原子过程而且罐头作为 epigenetic 标记被传递给女儿房间的 Histone 修正。积累的证据建议 histone 修正的关键函数是为下游的受动器的招募或活动发信号。这里,我们讨论 histone 修正读者的最近的发现并且修正语言怎么被解释。 | Miyong Yun Jun Wu Jerry L Workman Bing Li | 2011 | Cell Research2011,21,4: | 21 |
| 5 | 闽语里的古方言字显示文摘The chief task of Chinese historical dialectology is to explain how the present-day dialects were formed.This is not an easy task since we still have only a very incomplete record of modern words.Historical records of ancient dialects are unfortunately even more sparse,and while the recording of modern dialects is an on-going process,the amount of dialectal data known from written sources of early centuries is unlikely to increase appreciably.Moreover,dialectal data from historical sources is of a fragmentary and unsystematic nature.But despite these shortcomings,in some casesthese ancient recordings can and do shed light on problems in modern dialectology.In this paper I will examine a number of such ancient dialect words and attempt to interpret their significance. | JERRY NORMAN | 1983 | 方言1983,5,3: | 15 |
| 6 | 高效液相色谱-飞行时间质谱法筛查大豆中残留的多种除草剂和杀虫剂显示文摘应用高效液相色谱-飞行时间质谱建立了筛查大豆中77种除草剂和杀虫剂残留的新方法。在不同添加浓度下获得了精确的分子离子质量,质量偏差的绝对值低于3×10^-6。所有除草剂和杀虫剂在0.03~1.00mg/kg范围内线性关系良好(r≥0.99)。除一些除草剂外,多数除草剂和杀虫剂的添加回收率为60%~120%,在大豆基质中的检测限为0.003~0.026mg/kg。该方法适合于大豆中多种除草剂和杀虫剂残留的分析检测需要,方法简便、高效、准确。 | 储晓刚 雍炜 凌云 姚惠源 ZWEIGENBAUM Jerry 方晏燕 | 2007 | 色谱2007,25,6: | 15 |
| 7 | Bioactive hydrogels for bone regeneration显示文摘Bone self-healing is limited and generally requires external intervention to augment bone repair and regeneration.While traditional methods for repairing bone defects such as autografts,allografts,and xenografts have been widely used,they all have corresponding disadvantages,thus limiting their clinical use.Despite the development of a variety of biomaterials,including metal implants,calcium phosphate cements(CPC),hydroxyapatite,etc.,the desired therapeutic effect is not fully achieved.Currently,polymeric scaffolds,particularly hydrogels,are of interest and their unique configurations and tunable physicochemical properties have been extensively studied.This review will focus on the applications of various cutting-edge bioactive hydrogels systems in bone regeneration,as well as their advantages and limitations.We will examine the composition and defects of the bone,discuss the current biomaterials for bone regeneration,and classify recently developed polymeric materials for hydrogel synthesis.We will also elaborate on the properties of desirable hydrogels as well as the fabrication techniques and different delivery strategies.Finally,the existing challenges,considerations,and the future prospective of hydrogels in bone regeneration will be outlined. | Xin Bai Mingzhu Gao Sahla Syed Jerry Zhuang Xiaoyang Xu Xue-Qing Zhang | 2018 | Bioactive Materials2018,3,4: | 15 |
| 8 | 视网膜母细胞瘤的临床表现和诊断显示文摘视网膜母细胞瘤 (RB)是一种好发于 3岁以下儿童的高度恶性眼内肿瘤 ,其临床表现因就诊时疾病所处的阶段不同而不同。可表现为视网膜感觉层内的透明或半透明病灶 ;朦胧可见视网膜血管的白色混浊团块 ;继发视网膜脱离的视网膜下黄白色肿物等。任何大小的 RB均可表现为白瞳症。最常见的假性RB包括永存增生性原始玻璃体、Coats病和眼弓蛔虫病。对可疑 RB患儿的正确诊断过程 ,应包括详细的病史采集、体格检查、外眼检查、裂隙灯生物显微镜检查、结合巩膜压迫法的双目间接检眼镜检查等。B型超声和 CT检查可显示眼内肿瘤并检测出肿块内可能存在的钙化 ;MRI通常不能检测出钙化 ,但对评估视神经、眼眶和脑内是否有转移极具价值 ;光相干断层扫描可用于对化学药物治疗不敏感的囊性 RB检查以及评估随访患者的黄斑解剖结构。外周血和肿瘤组织的 DNA检测分析有助于鉴定患者是否存在种质(germline)突变。对具有 13号染色体长臂缺失综合征或其他面部畸形特征的儿童 ,染色体组型分析有可能早期检测出 RB。 | Carol L.Shields 孙红 张军军 Jerry A.Shields | 2004 | 中华眼底病杂志2004,20,2: | 15 |
| 9 | Bone morphogenetic protein-2 gene controls tooth root development in coordination with formation of the periodontium显示文摘Formation of the periodontium begins following onset of tooth-root formation in a coordinated manner after birth. Dental follicle progenitor cells are thought to form the cementum, alveolar bone and Sharpey's fibers of the periodontal ligament (PDL). However, little is known about the regulatory morphogens that control differentiation and function of these progenitor cells, as well as the progenitor cells involved in crown and root formation. We investigated the role of bone morphogenetic protein-2 (Bmp2) in these processes by the conditional removal of the Bmp2 gene using the Sp7-Cre-EGFP mouse model. Sp7-Cre-EGFP first becomes active at E18 in the first molar, with robust Cre activity at postnatal day 0 (P0), followed by Cre activity in the second molar, which occurs after P0. There is robust Cre activity in the periodontium and third molars by 2 weeks of age. When the Bmp2 gene is removed from Sp7+ (Osterix+) cells, major defects are noted in root, cellular cementum and periodontium formation. First, there are major cell autonomous defects in root-odontoblast terminal differentiation. Second, there are major alterations in formation of the PDLs and cellular cementum, correlated with decreased nuclear factor IC (Nfic), periostin and α-SMA+ cells. Third, there is a failure to produce vascular endothelial growth factor A (VEGF-A) in the periodontium and the pulp leading to decreased formation of the microvascular and associated candidate stem cells in the Bmp2-cKOSp7-Cre-EGFP . Fourth, ameloblast function and enamel formation are indirectly altered in the Bmp2-cKOSp7-Cre-EGFP . These data demonstrate that the Bmp2 gene has complex roles in postnatal tooth development and periodontium formation. | Audrey Rakian Wu-Chen Yang Jelica Gluhak-Heinrich Yong Cui Marie A Harris Demitri Villarreal Jerry Q Feng Mary MacDougall Stephen E Harris | 2013 | International Journal of Oral Science2013,5,2: | 14 |
| 10 | 数学教学中的开放式教学——创造一种课堂数学文化显示文摘数学教学中需要对开放式教学进行合作研究.在日本的开放式教学中,数学问题被选择是用来说明一个问题的多种解法或多个正确答案.数学教学要实现一种全新的课堂数学文化,这种教学形式的特点是:问题开放、解决问题的过程开放、构建问题开放、评价开放,使学生能自由地思考,发展学生的思维能力. | 桥本吉彦 Jerry Becker 孙连举 于卓 | 2002 | 数学教育学报2002,11,1: | 14 |
| 11 | 在DEA模型中应用病例组合指数评价医院服务效率显示文摘目的 应用病例组合指数在DEA模型中估计医院的相对服务效率。方法 首先应用信息理论计算病例组合指数 ,再将其与出院人数的乘积 (产出量 )作为产出指标 ,在DEA模型中估计医院的相对服务效率。结果 应用病例组合指数所得到的效率值更加合理准确 ;大多数医院处于规模收益递减、低效率的运行状态。结论 此方法考虑到了疾病严重程度对于医院服务效率的影响 ,使估计的效率值更加准确。 | 李杰 姜潮 刘宗航 Jerry Han 刘启贵 司丹 禹海波 王蕾 胡冬梅 | 2003 | 中国卫生统计2003,20,5: | 13 |
| 12 | Method for prevention and control of spontaneous combustion of coal seam and its application in mining field显示文摘Spontaneous combustion of coal seam has been and continues to be a big problem in coal mines. It could pose great threat to the safety of the whole mine and all miners, especially when it occurs in or nearby coal mines. Besides, environment of area surrounded mines during combustion can be threatened where large amount of toxic gases including CO_2, CO, SO_2 and H_2S can be leased by fire in mine. Hence, it is important and significant for scholars to study the controlling and preventing of the coal seam fire. In this paper, the complicated reasons for the occurrence and development of spontaneous combustion in coal seam are analysed and different models under various air leakage situations are built as well. Based on the model and approximately calculation, the difficulty of fire extinguishment in coal seam is pointed out as the difficulty and poor effect to remove the large amount of heat released. Detailed measurements about backfilling and case analyses are also provided on the basis of the recent ten years' practice of controlling spontaneous combustion in coal seams in China. A technical fire prevention and control method has been concluded as five steps including detection, prevention, sealing, injection and pressure adjustment. However, various backfill materials require different application and environmental factors, so in this paper, analyses and discussion about the effect and engineering application of prevention of spontaneous combustion are provided according to different backfilling technologies and methods. Once the aforementioned fire prevention can be widely applied and regulated in mines, green mining will be achievable concerning mine fire prevention and control. | Wei Lu Ying-Jiazi Cao Jerry C.Tien | 2017 | International Journal of Mining Science and Technology2017,27,5: | 11 |
| 13 | 基于模型的构件软件修改影响分析显示文摘基于构件的软件构建方法目前被广泛使用在软件开发中,用于减少软件开发的工程成本和加快软件开发进度.面向构件的系统主要由第三方提供的可重用构件或者内建的可重用构件组成,因此,系统的质量好坏和维护的难易程度依赖于构件的品质.一个软件修改会给其他构件甚至整个系统带来影响,而修改影响分析是控制和消除这类影响的有效手段.然而,现有的研究很少涉及构件软件的修改影响分析,尤其缺少对系统层面的修改影响分析研究.提出了一种基于模型的系统化修改影响分析方法,该方法的基本思路是:首先提出构件及系统层面的修改影响分析模型,然后根据分析模型分别从构件和系统两个层面对构件软件修改前后的版本进行修改识别,并且利用'防火墙'方法进行影响分析.理论分析和实验结果表明,该方法是可行的,也是有效的. | 陶传奇 李必信 Jerry GAO 孙小兵 | 2013 | 软件学报2013,24,5: | 10 |
| 14 | The Arabidopsis P450 protein CYP82C2 modulates jasmonateinduced root growth inhibition, defense gene expression and indole glucosinolate biosynthesis显示文摘Jasmonic 酸(JA ) 是对草食动物和一些微生物引起的病原体调整大量植物防卫回答的一个丰满的导出酸的发信号分子。分子的基因研究证实了 JA 也在植物开发的几个方面执行一个关键角色。这里,我们描述 Arabidopsis 变异的 jasmonic acid-hypersensitive1-1 (jah1-1 ) 的描述,它在 JA 回答的几个方面是有缺点的。尽管异种在根生长抑制展出增加的敏感到 JA,它显示出 JA 可诱导的防卫基因和减少的抵抗的减少的表示到 necrotrophic 真菌 Botrytis cinerea。基因克隆研究显示这些缺点被一个变化在细胞色素 P450 蛋白质 CYP82C2 引起。我们提供证明的证据到 B 的 jah1-1 异种的损害抵抗。cinerea 被导致 JA 的防卫基因的减少的表示伴随并且减少了导致 JA 的吲哚 glucosinolates (IG ) 的累积。相反地,提高的抵抗到 B。在 CYP82C2-overexpressing 植物的 cinerea 被导致 JA 的防卫基因的增加的表示伴随并且提高了导致 JA 的 IG 的层次。我们证明 CYP82C2 影响 IG biosynthetic 先锋的导致 JA 的累积色氨酸(Trp ) ,然而并非导致 JA 的 IAA 或导致病原体的 camalexin。一起,我们 CYP82C2 可以在导出 Trp 的第二等的代谢物的新陈代谢扮演在下面的一个假设在 JA 在哪个铺平调节的结果支持被提高。jah1-1 异种应该因此在向理解位于调停 JA 的微分回答的复杂性下面的机制的未来研究是重要的,它是重要的让植物使他们的生长适应千变万化环境。 | Fang Liu Hongling Jiang Songqing Ye Wen-Ping Chen Wenxing Liang Yingxiu Xu Bo Sun Jiaqiang Sun Qiaomei Wang Jerry D Cohen Chuanyou Li | 2010 | Cell Research2010,20,5: | 10 |
| 15 | 典型重金属污染地区蔬菜中重金属含量及健康风险显示文摘在大冶市典型重金属污染地区,选择罗家桥街办作为污染区、茗山乡作为对照区,通过采集土壤和蔬菜样品,分析5种重金属(Cu、Zn、As、Cd、Pb)的含量,评价重金属对当地居民的健康风险,评价参数根据当地居民调查得到。结果表明,污染区土壤样品的5种重金属的平均值均高于背景值,对照区土壤样品的5种重金属的平均值与背景值差异不显著或低于背景值。污染区蔬菜样品的5种重金属的平均值也基本都高于对照区。因此,污染区土壤已经受到了重金属的污染,对照区土壤几乎未受到重金属的污染。健康风险评价结果表明,污染区人群面临着非致癌风险和致癌风险,而对照区健康风险较小。从年龄层看,对非致癌风险抵抗力最弱的是儿童,而对致癌风险抵抗力最弱的是成人。污染区最主要的风险元素是Cd和As。 | 杨俊 吕府红 宋永伟 张敬东 Jerry Blomberg | 2017 | 环境污染与防治2017,39,9: | 10 |
| 16 | DPM dissipation experiment at MST's experimental mine and comparison with CFD simulation显示文摘 | ZHENG Yi LAN Hai THIRUVENGADAM Magesh TIEN Jerry C | 2011 | Journal of Coal Science & Engineering(China)2011,17,3: | 9 |
| 17 | A comparative study on polypropylene separators coated with different inorganic materials for lithium-ion batteries显示文摘 | Linghui Yu Jiansong Miao Yi Jin Jerry Y.S. Lin | 2017 | Frontiers of Chemical Science and Engineering2017,11,3: | 9 |
| 18 | 美国体操运动员的培养现状及其启示显示文摘为促进我国体操事业的可持续发展,同时也为能够吸取发达国家体操管理机制的成功经验,运用文献资料法和调查访问法介绍了美国体操运动员培养的现状和管理机制,并对其进行适当的分析和研究,以期为解决我国体操运动员培养过程中所出现的问题提供参考和借鉴。 | 丁励翼 Jerry D. Reighard | 2008 | 成都体育学院学报2008,34,2: | 9 |
| 19 | 玉树地震地表破裂特征及其破裂方式显示文摘北京时间2010年4月14日玉树Ms7.1级地震产生了长约50km的地表破裂带,地表破裂系统非常典型。本文通过对果庆益荣松多村附近河滩与结古镇西南河道两岸2个地表破裂点的野外观测和地表破裂的力学分析,探讨玉树地震地表破裂特征和方式。在果庆益荣松多村附近河滩地表破裂与地震陡坎呈间隔式左行右阶排列,具转换压缩性质;在结古镇西南河道北岸主地表破裂带中地表破裂非常发育,出露一处古断层面。地表破裂的野外调查与应力分析结果表明,玉树地震同震地表破裂带总体走向为125°,属于典型的左行走滑破裂带,最大左行走滑位移量1.75m,主压应力为近东西向,这一结果与美国地质调查局和中国地震局地震地球物理研究所公布的结果基本一致。 | 程丰 李德威 Jerry Bartholomew 罗文行 | 2012 | 大地构造与成矿学2012,36,1: | 8 |
| 20 | Weight gain following breast cancer diagnosis: Implication and proposed mechanisms显示文摘Weight gain occurs in the majority of women following breast cancer treatment. An overview of studies describing weight gain amongst women treated with early to modern chemotherapy regimens is included. Populations at higher risk include women who are younger, closer to ideal body weight and who have been treated with chemotherapy. Weight gain ranges between 1 to 5 kg, and may be associated with change in body composition with gain in fat mass and loss in lean body mass. Women are unlikely to return to pre-diagnosis weight. Possible mechanisms including inactivity and metabolic changes are explored. Potential interventions are reviewed including exercise, dietary changes andpharmacologic agents. Although breast cancer prognosis does not appear to be significantly impacted, weight gain has negative consequences on quality of life and overall health. Future studies should explore change in body composition, metabolism and insulin resistance. Avoiding weight gain in breast cancer survivors following initial diagnosis and treatment should be encouraged. | Grace Makari-Judson Barry Braun D Joseph Jerry Wilson C Mertens | 2014 | World Journal of Clinical Oncology2014,5,3: | 8 |