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| 1 | European vs 2015-World Health Organization clinical molecular and pathological classification of myeloproliferative neoplasms显示文摘The BCR/ABL fusion gene or the Ph^1-chromosome in the t(9;22)(q34;q11)exerts a high tyrokinase acticity,which is the cause of chronic myeloid leukemia(CML).The1990 Hannover Bone Marrow Classification separated CML from the myeloproliferative disorders essential thrombocythemia(ET),polycythemia vera(PV)and chronic megakaryocytic granulocytic myeloproliferation(CMGM).The 2006-2008 European Clinical Molecular and Pathological(ECMP)criteria discovered 3variants of thrombocythemia:ET with features of PV(prodromal PV),'true'ET and ET associated with CMGM.The 2008 World Health Organization(WHO)-ECMP and 2014 WHO-CMP classifications defined three phenotypes of JAK2^(V617F)mutated ET:normocellular ET(WHO-ET),hypercelluar ET due to increased erythropoiesis(prodromal PV)and ET with hypercellular megakaryocytic-granulocytic myeloproliferation.The JAK2^(V617F)mutation load in heterozygous WHO-ET is low and associated with normal life expectance.The hetero/homozygous JAK2^(V617F)mutation load in PV and myelofibrosis is related to myeloproliferative neoplasm(MPN)disease burden in terms of symptomaticsplenomegaly,constitutional symptoms,bone marrow hypercellularity and myelofibrosis.JAK2 exon 12mutated MPN presents as idiopathic eryhrocythemia and early stage PV.According to 2014 WHO-CMP criteria JAK2 wild type MPL^(515)mutated ET is the second distinct thrombocythemia featured by clustered giant megakaryocytes with hyperlobulated stag-horn-like nuclei,in a normocellular bone marrow consistent with the diagnosis of'true'ET.JAK2/MPL wild type,calreticulin mutated hypercellular ET appears to be the third distinct thrombocythemia characterized by clustered larged immature dysmorphic megakaryocytes and bulky(bulbous)hyperchromatic nuclei consistent with CMGM or primary megakaryocytic granulocytic myeloproliferation. | Jan Jacques Michiels Fransje Valster Jenne Wielenga Katrien Schelfout Hendrik De Raeve | 2015 | World Journal of Hematology2015，4，3： | 3 |
| 2 | Physical Activity and Pregnancy: Past and Present Evidence and Future Recommendations显示文摘 | Downs Danielle Symons Chasan-Taber Lisa Evenson KeIly R Leiferman Jenn Yeo SeonAe | 2012 | Research Quarterly for Exercise and Sport2012，，4： | 2 |
| 3 | Comparison of various approaches to model thethermal load on the EDM wire electrode显示文摘 | Jennes M | 1984 | Annals of theCIRP1984，33，1： | 1 |
| 4 | Combined effects of dietary phosphatidylcholine and cholesterol on the growth, survival and body lipid composition of marine shrimp, Penaeus penicillatus 显示文摘 | Chen H Y Jenn J S | 1991 | Aquaculture1991，96，： | 1 |
| 5 | T-bet-dependent S1 P5 expression in NK cells promotes egress from lymph nodes and bone marrow显示文摘 | Jenne C N Enders A Rivera R | 2009 | The Journal of experimental medicine2009，206，11： | 1 |
| 6 | Genomic organization and subchromosomal in situ localization of the murine granzyme F, a serine protease expressed in CD8^+ T cells显示文摘 | Jenne DE Zimmer M Garcia Sanz JA | 1991 | J Immunol1991，147，3： | 1 |
| 7 | Comparison of various approaches to model the thermal load on the EDM wire electrode显示文摘 | Jennes M Snoeys R Dekseyer W | 1984 | Annals of the CIRP1984，33，1： | 1 |
| 8 | The Relationship of Hardiness, Coping Strategies, and Perceived Stress to Symptoms of Illness显示文摘 | Mike Soderstrom Christyn Dolbier Jenn Leiferman Mary Steinhardt | 2000 | Journal of Behavioral Medicine2000，，3： | 1 |
| 9 | LPS-binding protein and IL-6 mark paradoxical tuberculosis immune reconstitu- tion inflammatory syndrome in HIV patients显示文摘 | Goovaerts O Jennes W Massinga-Loembe M | 2013 | PLoS One2013，8，81： | 1 |
| 10 | Intravascular Neutrophil Extracellular Traps Capture Bacteria from the Bloodstream during Sepsis显示文摘 | Braedon McDonald Rossana Urrutia Bryan G. Yipp Craig N. Jenne Paul Kubes | 2012 | Cell Host & Microbe2012，，： | 1 |
| 11 | Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase 显示文摘 | Jenne DE Reimann H Nezu J | 1998 | Nat Genet1998，18，1： | 1 |
| 12 | A new noninvasive approach in breast cancer therapy using magnetic resonance imaging-guided focused ultrasound surgery显示文摘 | Huber P E Jenne J W Rastert R | 2001 | Cancer Research2001，61，23： | 1 |
| 13 | Functional innervation of hepatic iNKT cells is immunosuppressive following stroke显示文摘 | Wong CH Jenne CN Lee WY | 2011 | Science2011，334，652： | 1 |
| 14 | Effect of polysaccharides on textural characteristics of soy protein isolate emulsion显示文摘 | Jenn Shou Tsai Koji Yamada Hiroki Murakami | 1989 | Nippon Shokuhin Kogyo Gokkaishi1989，36，9： | 1 |
| 15 | Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps 显示文摘 | Jenne C N Wong C H Y Zemp F J | 2013 | Cell Host Microbe2013，13，2： | 1 |
| 16 | The NLRP3/ASC/Caspase-1 axis regulates IL - 113 processing in neutrophils显示文摘 | Mankan AK Dau T Jenne D | 2012 | EurJ Immunol2012，42，3： | 1 |
| 17 | Importance of nausea显示文摘 | Jenns K | 1994 | Cancer Nurs1994，17，： | 1 |
| 18 | Trimodal cancer treatment:beneficial effects of combined antiangiogenesis,radiation,and chemotherapy显示文摘 | Huber PE Bischof M Jenne J | 2005 | Cancer Res2005，65，9： | 1 |
| 19 | Nucleotide sequence and organi-zation of the human S-protein gene:repeating peptide motifsin the“pexin”family and a model for their evolution显示文摘 | JENNE D STANLEY K K | 1987 | Bio-chemistry1987，26，21： | 1 |
| 20 | LHRH-systems in the brain of the golden hamster显示文摘 | Dr. Lothar Jennes Walter E. Stumpf | 1980 | Cell and Tissue Research1980，，2： | 1 |
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