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| 1 | Extrahepatic complications to cirrhosis and portal hypertension: Haemodynamic and homeostatic aspects显示文摘In addition to complications relating to the liver, patients with cirrhosis and portal hypertension develop extrahepatic functional disturbances of multiple organ systems. This can be considered a multiple organ failure that involves the heart, lungs, kidneys, the immune systems, and other organ systems. Progressive fibrosis of the liver and subsequent metabolic impairment leads to a systemic and splanchnic arteriolar vasodilatation. This affects both the haemodynamic and functional homeostasis of many organs and largely determines the course of the disease. With the progression of the disease, the circulation becomes hyperdynamic with cardiac, pulmonary as well as renal consequences for dysfunction and reduced survival. Infections and a changed cardiac function known as cirrhotic cardiomyopathy may be involved in further aggravation of other complications such as renal failure precipitatingthe hepatorenal syndrome.Patients with end-stage liver disease and related complications as for example the hepatopulmonary syndrome can only radically be treated by liver transplantation.As a bridge to this treatment,knowledge on the mechanisms of the pathophysiology of complications is essential for the choice of vasoactive drugs,antibiotics,drugs with specific effects on fibrogenesis and inflammation,and drugs that target specific receptors. | S?ren M?ller Jens H Henriksen Flemming Bendtsen | 2014 | World Journal of Gastroenterology2014,20,42: | 14 |
| 2 | 用传统方法与计算机辅助精液分析软件CRISMAS分析166名丹麦青年男性精液样本的结果比较显示文摘本研究以166名丹麦青年男性精液为样本,通过评估精于浓度和活力来比较传统精液分析与计算机辅助精液分析方法(CASA)(哥本哈根Rigshospitalet图像屋精子运动分析系统,CRISMAS软件4.6版本)。CRISMAS软件测定精子的浓度把精子活力分为三类。传统分析方法将精子活力分为四种状态。为了便于二者的比较,本文将传统的四种状态根据精子速度等级重新分为三个状态:rapidly progressive(A),slowly progressive(B)和non-progressive(C+D)。两种方法所研究的参数之间都有显著差异(P〈0.001)。与传统方法相比,CRISMAS高估了精子浓度以及快速运动精子的比例,因而低估了慢速运动和非运动精子。为分析研究结果是否会随精液分析时间而起伏变动,将精液分析结果按分析同期分为四个层次。结果表明CRISMAS对活力的分析结果比传统分析方法稳定,但两种方法都未表现出任何趋势。显然,无法比较CRISMAS CASA和传统分析方法在精子浓度和精子活力方面的分析结果。在临床上使用该软件时以及用其研究这些精子特性时需要说明这一点。 | Anne Vested Cecilia H Ramlau-Hansen Jens P Bonde Ane M Thulstrup Susanne L Kristensen Gunnar Toft | 2011 | Asian Journal of Andrology2011,13,3: | 3 |
| 3 | Hydration simulation of C3S显示文摘 | JENNINGS H M JOHNSON | 1986 | Am Ceram Soc1986,69,5: | 1 |
| 4 | A model for the microstructure of calcium silicate hydrate in cement paste 显示文摘 | JENNINGS H M | 2000 | Cem Coner Res2000,30,1: | 1 |
| 5 | Colloid model of C-S-H and implications to the problem of creep and shrinkage 显示文摘 | JENNINGS H M | 2004 | Mater Struct: Concr Sei Eng2004,37,1: | 1 |
| 6 | Simulation of Microstructure Development During the Hydration of a Cement Compound 显示文摘 | Jennings H M Johnson S K | 1986 | Journal of the American Ceramic Society1986,69,11: | 1 |
| 7 | Mechanisms of cement hydration 显示文摘 | BULLARD J W JENNINGS H M LIVINGSTON R A | 2011 | Cem Concr Res2011,41,12: | 1 |
| 8 | Myocardialnecrosis induced by temporary occlusion of coronary atery in the dog 显示文摘 | Jennings R B Sommers H M Smyth G A | 1960 | Arch Pathol1960,70,1: | 1 |
| 9 | Refinements to colloid model of C-S-H in cement: CM-II 显示文摘 | JENNINGS H M | 2008 | Cem Concr Res2008,38,3: | 1 |
| 10 | A multi-technique investigation of the nanoporosity of cement paste显示文摘 | JENNINGS H M THOMAS J J GEVRENOV J S | 2007 | Cement and Concrete Research2007,,37: | 1 |
| 11 | Composition and density of nanoscale calcium-silicate-hydrate in cement 显示文摘 | ALLEN A J THOMAS J J JENNINGS H M | 2007 | Nat Mater2007,6,4: | 1 |
| 12 | A generalized approach for the determination of yield stress by slump and slump flow显示文摘 | SAAK A W JENNINGS H M SHAH S P | 2004 | Cement and Concrete Research2004,34,3: | 1 |
| 13 | Mechanisms of cement hydration 显示文摘 | BULLARD J W JENNING H M LIVINGSTON R A | 2011 | Cem Concr Res2011,41,12: | 1 |
| 14 | A generalized ap-proach for the determination of yield stress by slump andslump flow显示文摘 | Saak A W Jennings H M Shah S P | 2004 | Cement Concrete Research2004,34,3: | 1 |
| 15 | Characterization and Modeling of Pores and Surfaces in Cement Paste: Correlations to Processing and Properties 显示文摘 | JENNINGS H M BULLARD J W THOMAS J J | 2008 | Journal of Advanced ConcreteTechnology2008,6,1: | 1 |
| 16 | Decalcifica- tion shrinkage of cement paste显示文摘 | JEFFREY J C THOMAS J J JENNINGS H M | 2006 | Cem Concr Res2006,36,5: | 1 |
| 17 | Damage to the pore structure of hardened portland cement paste by mercury intrusion显示文摘 | OLSON R A NEUBAUER C M JENNINGS H M | 1997 | J Am Ceram Soc1997,80,9: | 1 |
| 18 | A multi-technique investigation of the nanoporosity of cement paste 显示文摘 | Jennings H M Thomas J J Gevrenov J S | 2007 | Cement and Concrete Research2007,37,3: | 1 |
| 19 | The Strength of Bolted and Bonded Single-Lapped Composite Joints in Tension显示文摘 | Jen M H | 1999 | Journal of Composite Materials1999,33,7: | 1 |
| 20 | The surface area of hardened cement paste as measured by various techniques显示文摘 | THOMAS J J JENNINGS H M ALLEN A J | 1999 | Concr Sci Eng1999,,3: | 1 |