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| 1 | Complement and its role in innate and adaptive immune responses显示文摘补充系统对普通病原体在天生的防卫起一个关键作用。补充的激活导致柔韧、有效的解朊的串联,它通过有势力 proinflammatory 分子的生产在病原体以及在古典煽动性的反应的产生的 opsonization 和细胞溶解终止。然而,更最近,在有免疫力的反应的补充的角色由于连接补充激活到适应有免疫力的回答的观察被扩展了。补充是在允许综合主人防卫到病原的挑战的天生、适应的有免疫力的回答之间的一座功能的桥,这现在被欣赏。因此,它的函数的研究象主机免疫者反应的组织和组织一样允许卓见进主人病原体相互作用的分子的 underpinnings。这评论试图总结在主人防卫上在天生、适应的有免疫力的回答和这些相互作用的后果补充戏的角色。 | Jason R Dunkelberger Wen-Chao Song | 2010 | Cell Research2010，20，1： | 57 |
| 2 | A community-derived classification for extant lycophytes and ferns显示文摘发展史长通知了蕨类植物分类。当我们推断进化的树的能力改善了,针对认出生来的组的分类变得逐渐地预兆、稳定。这里,我们为 lycophytes 和蕨纲植物提供一个现代、全面分类,在下面,利用一条基于社区的途径类水平。我们 monophyly 用作主要标准让 taxa,而且目的识别保存两个广泛地被接受的存在 taxa 和界限并且与我们蕨类植物发展史的理解一致。总共,这个分类对待一在 337 个类, 51 个家庭, 14 目,和二个班估计了 11 916 种类。这个分类没在 lycophyte 和蕨纲植物上作为最后的词被打算分类,而是当前的假设的概括陈述,源于最好的可得到的数据并且在问题由熟悉植物的那些大多数塑造了。我们希望它将在蕨类植物上为最近的文学的那些想要的参考用作一个资源发展史和分类,为指导未来调查的一个框架,和推进讲话的刺激。 | Eric Schuettpelz Harald Schneider Alan R. Smith Peter Hovenkamp Jefferson Prado Germinal Rouhan Alexandre Salino Michael Sundue Thafs Elias Almeida Barbara Parris Emily B. Sessa Ashley R. Field Andre Luis de Gasper Carl J. Rothfels Michael D. Windham Marcus Lehnert Benjamin Dauphin Atsushi Ebihara Samuli Lehtonen Pedro Bond Schwartsburd Jordan Metzgar Li-Bing Zhang Li-Yaung Kuo Patrick J. Brownsey Masahiro Kato Marcelo Daniel Arana Francine C. Assis Michael S. Barker David S. Barrington Ho-Ming Chang Yi-Han Chang Yi-Shan Chao Cheng-Wei Chen De-Kui Chen Wen-Liang Chiou Vinicius Antonio de Oliveira Dittrich Yi-Fan Duan Jean-Yves Dubuisson Donald R. Farrar Susan Fawcett Jose Maria Gabriel y Galan Luiz Armando de Araujo Goes-Neto Jason R. Grant Amanda L. Grusz Christopher Haufler Warren Hauk Hai He Sabine Hennequin Regina Yoshie Hirai Layne Huiet Michael Kessler Petra Korall Paulo H. Labiak Anders Larsson Blanca Leen Chun-Xiang Li Fay-Wei Li Melanie Link-Perez Hong-Mei Liu Ngan Thi Lu Esteban I. Meza-Torres Xin-Yuan Miao Robbin Moran Claudine Massi Mynssens Nathalie Nagalingum Benjamin Ollgaard Alison M. Paul Jovani B. de S. Pereira Leon R. Perrie Monica Ponce Tom A. Ranker Christian Schulz Wataru Shinohara Alexander Shmakov Erin M. Sigel Filipe Soares de Souza Lana da Silva Sylvestre Weston Testo Luz Amparo Triana-Moreno Chie Tsutsumi Hanna Tuomisto IvAn A. Valdespino Alejandra Vasco Raquel Stauffer Viveros Alan Weakley Ran Wei Stina Weststrand Paul G. Wolf George Yatskievych Xiao-Gang Xu Yue-Hong Yan Liang Zhang Xian-Chun Zhang Xin-Mao Zhou | 2016 | Journal of Systematics and Evolution2016，54，6： | 44 |
| 3 | Where Does AlphaGo Go: From Church-Turing Thesis to AlphaGo Thesis and Beyond显示文摘An investigation on the impact and significance of the Alpha Go vs. Lee Sedol Go match is conducted, and concludes with a conjecture of the Alpha Go Thesis and its extension in accordance with the Church-Turing Thesis in the history of computing. It is postulated that the architecture and method utilized by the Alpha Go program provide an engineering solution for tackling issues in complexity and intelligence. Specifically,the Alpha Go Thesis implies that any effective procedure for hard decision problems such as NP-hard can be implemented with Alpha Go-like approach. Deep rule-based networks are proposed in attempt to establish an understandable structure for deep neural networks in deep learning. The success of Alpha Go and corresponding thesis ensure the technical soundness of the parallel intelligence approach for intelligent control and management of complex systems and knowledge automation. | Fei-Yue Wang Jun Jason Zhang Xinhu Zheng Xiao Wang Yong Yuan Xiaoxiao Dai Jie Zhang Liuqing Yang | 2016 | IEEE/CAA Journal of Automatica Sinica2016，3，2： | 44 |
| 4 | Renminbi Internationalization: Progress, Prospect and Comparison显示文摘<正>Using principal component analyses,this paper constructs two internationalization indices for the renminbi(RMB) and 32 other major currencies.We find that the RMB’s currency internationalization degree index(CIDI) is still low,and far behind the 4 most important international currencies.In 2009,it was ranked 18th among all important international currencies.However,in terms of the currency internationalization prospect index(CIPI), the RMB has remained the world’s fifth highest since 2006.Although it is still far behind the US dollar and the euro,surpassing the ranking of the yen and the pound is possible in the near future.The dramatic difference in the ranking between the CIDI and the CIPI is a result of China’s tight capital account control,the usage continuity of international currency due to network externalities,and the narrow foreign exchange and imperfect financial markets.Hence,to a large degree,the RMB’s potential as an international currency depends on China’s capital account liberalization. | Chen-yuan Tung Guo-chen Wang Jason Yeh | 2012 | China & World Economy2012，20，5： | 39 |
| 5 | 我国婴幼儿中存在不同基因型杯状病毒的感染显示文摘Human caliciviruses were detected from stool specimens collected from infants with diarrhea from Beijing and Anhui Province by using RT PCR PCR products with molecular weight around 330 were obtained by using the primer pair of 289/290,which is proved to be able to amplify both Norwalk like and Sapporo like human caliciviruses The PCR products amplified from specimens collected in Beijing(CR480) and Anhui(A141) were cloned into the T A cloning vector pUCm T and sequenced The cDNA fragment amplified from CR480 is 319bp in length,which is consistent with the molecular weight of the cDNA fragment amplified from Norwalk like viruses with the primer pair 289/290,whereas the cDNA fragment amplified from A141 is 331 bp in length,which is the size of the cDNA fragment from Sapporo like viruses The sequence analysis revealed that the cDNA from CR480(the stool specimen collected in Beijing) shared higher nucleotide and amino acid identities with selected Norwalk like viruses (from 60% to 97% and 62% to 99%,respectively)than with selected Sapporo like viruses(less than 58%),having the highest identity with Takl 1999 jp and ARG320,which belong to genotype Ⅱ of Norwalk like viruses The sequence of the cDNA from A141 (collected form Anhui Province) shared higher nucleotide and amino acid identities with selected Sapporo like viruses(from 68% to 92% and 75% to 96%,respectively) than with selected Norwalk like viruses(less than 52%) It suggests that both Norwalk like and Sapporo like human caliciviruses are circulating in China and cause diarrhea in infants and young | 陈冬梅 张又 钱渊 Jason Jiang | 2001 | 病毒学报2001，17，3： | 37 |
| 6 | XLPE电缆及接头局部放电的超高频测量与分析显示文摘超高频的局部放电测量是目前国外电力设备绝缘检测研究的焦点问题之一。本文建立了一套超高频局部放电的测量系统 ,设计了XLPE电力电缆及其接头局部放电超高频测量的电容耦合传感器 ,分析了传感器的等效电路 ,测量了其频率响应 ,对电缆以及接头中的实际放电进行了测量分析。 | 徐阳 钟力生 曹晓珑 G CHEN Jason Y TIAN A E DAVIES | 2002 | 电工电能新技术2002，21，1： | 31 |
| 7 | Spatiotemporal vegetation cover variations in the Qinghai-Tibet Plateau under global climate change显示文摘Empirical Orthogonal Function (EOF) analysis and the related Principal Components (PC) analysis are used to extract valuable vegetation cover derived information from the National Oceanic and Atmos- pheric Administration (NOAA-AVHRR)'s Leaf Area Index (LAI) satellite images. Results suggest that from 1982 to 2000 global climate change has contributed to an increase in vegetation cover in the Qinghai-Tibet Plateau. The correlation between rainfall and LAI EOF PC1 and PC2 indicates that rainfall is the major climatic factor influencing interannual variations of average vegetation cover throughout the entire Plateau. However, annual mean vegetation cover trends in the Qinghai-Tibet Plateau are mainly out of phase with air temperature increasing, which is primarily responsible for nonsynchro- nous changes of vegetation cover. In the southern ridge of the Qinghai-Tibet Plateau, recent warming trends contribute to humid weather and favorable conditions for vegetation growth. By contrast, higher temperatures have led to arid conditions and insufficient rainfall in the northern part of the Plateau, leading to drought and other climatic conditions which are not conducive to increased vegetation cover. | XU XingKui CHEN Hong Jason K LEVY | 2008 | Chinese Science Bulletin2008，53，6： | 28 |
| 8 | Magnesium lithospermate B possesses inhibitory activity on Na^+,K^+-ATPase and neuroprotective effects against ischemic stroke显示文摘瞄准:如果镁 lithospermate B (MLB ) 从 Danshen 提取了,检验,鼠尾草植物 miltiorrhiza 的弄干的根,当为经由一样的分子的机制的这繁体中文植物的 cardiactherapeutic 效果负责的一个活跃部件触发了 bycardiac glycosides,可以行动,例如 ouabain 和异羟基洋地黄毒苷。而且,如果,我们想要测试 MLB 对 ischemic 的 provideneuroprotection 可以是为心脏的 glycosides 观察了摸。方法:在 MLB 和 ouabain 之间的类似 inthe 化学药品结构和分子的配置被分析。Na+ 上的 MLB 和 ouabain 的 Theinhibition 力量,一个商业产品的 K+-ATPase 活动,也, asin 从老鼠大脑和心纸巾净化了膜部分,被检验,对 ischemic 击的 MLB 的 compared.Neuroprotective 效果也用一个外皮的基于 brainslice 的试金模型被评估。结果:商业 Na+ 上的剂量依赖者抑制,为 ouabain 的到那的 K+-ATPaseequivalent 为 MLB 被观察近似由重量的半剂量。ouabain 和 MLB 的 Thisrelative 力量也在 Na+ 上为他们的抑制被观察,从老鼠纸巾净化的 K+-ATPase activityof 血浆膜,尽管这 2 个禁止者有点在这些粗略的摘录展出了 lowercompetence。在 ischemic 沙鼠大脑,与 MLB significantlyreduced 处理以后梗塞尺寸,由 2,3,5-triphenyltetrazolium 氯化物染色设想了, byapproximately 55% 什么时候与控制组相比。结论:这些结果显然 suggestthat Danshen 的心脏的治疗学的效果应该部分至少被归因于 Na+ ,由 MLB 的 K+-ATPase,和那 MLB 的 effectiveinhibition 在 gerbilssubjected 提供 anti-ischemic neuroprotection 给焦点的局部缺血和灌注。 | Jason TC TZEN Tzyy-rong JINN Yi-ching CHEN Feng-yin LI Fu-chou CHENG Li-shian SHI Hank KH SHE Balance CM CHEN Vic HSIEH Mu-lin TU | 2007 | Acta Pharmacologica Sinica2007，28，5： | 25 |
| 9 | Novel concepts in radiation-induced cardiovascular disease显示文摘Radiation-induced cardiovascular disease(RICVD) is the most common nonmalignant cause of morbidity and mortality among cancer survivors who have undergone mediastinal radiation therapy(RT).Cardiovascular complications include effusive or constrictive pericarditis,cardiomyopathy,valvular heart disease,and coronary/vascular disease.These are pathophysiologically distinct disease entities whose prevalence varies depending on the timing and extent of radiation exposure to the heart and great vessels.Although refinements in RT dosimetry and shielding will inevitably limit future cases of RICVD,the increasing number of long-term cancer survivors,including those treated with older higher-dose RT regimens,will ensure a steady flow of afflicted patients for the foreseeable future.Thus,there is a pressing need for enhanced understanding of the disease mechanisms,and improved detection methods and treatment strategies.Newly characterized mechanisms responsible for the establishment of chronic fibrosis,such as oxidative stress,inflammation and epigenetic modifications,are discussed and linked to potential treatments currently under study.Novel imaging modalities may serve as powerful screening tools in RICVD,and recent research and expert opinion advocating their use is introduced.Data arguing for the aggressive use of percutaneous interventions,such as transcutaneous valve replacement and drug-eluting stents,are examined and considered in the context of prior therapeutic approaches.RICVD and its treatment options are the subject of a rich and dynamic body of research,and patients who are at risk or suffering from this disease will benefit from the care of physicians with specialty expertise in the emerging field of cardiooncology. | Jason R Cuomo Gyanendra K Sharma Preston D Conger Neal L Weintraub | 2016 | World Journal of Cardiology2016，8，9： | 17 |
| 10 | Ecological niche suitability model with an application in Taojiang land use planning显示文摘EcologicalnichesuitabilitymodelwithanapplicationinTaojianglanduseplanningOuyangZhiyun;WeismanJason;WangRusong(ResearchCenterf... | Ouyang Zhiyun Weisman Jason Wang Rusong(Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences , Beijing 100085, China) Fu Guinan (Taojiang County Land Bureau, Hunan Province, China) | 1994 | Journal of Environmental Sciences1994，6，4： | 17 |
| 11 | Hepatitis B virus and micro RNAs:Complex interactions affecting hepatitis B virus replication and hepatitis B virusassociated diseases显示文摘Chronic infection with the hepatitis B virus(HBV) is the leading risk factor for the development of hepatocellular carcinoma(HCC). With nearly 750000 deaths yearly, hepatocellular carcinoma is the second highest cause of cancer-related death in the world. Unfortunately, the molecular mechanisms that contribute to the development of HBV-associated HCC remain incompletely understood. Recently, micro RNAs(mi RNAs), a family of small non-coding RNAs that play a role primarily in post-transcriptional gene regulation, have been recognized as important regulators of cellular homeostasis, and altered regulation of mi RNA expression has been suggested to play a significant role in virus-associated diseases and the development of many cancers. With this in mind, many groups have begun to investigate the relationship between mi RNAs and HBV replication and HBV-associated disease. Multiple findings suggest that some mi RNAs, such as mi R-122, and mi R-125 and mi R-199 family members, are playing a role in HBV replication and HBV-associated disease, including the development of HBV-associated HCC. In this review, we discuss the current state of our understanding of the relationship between HBV and mi RNAs, including how HBV affects cellular mi RNAs, how these mi RNAs impact HBV replication, and the relationship between HBV-mediated mi RNA regulation and HCC development. We also address the impact of challenges in studying HBV, such as the lack of an effective model system for infectivity and a reliance on transformed cell lines, on our understanding of the relationship between HBV and mi RNAs, and proposepotential applications of mi RNA-related techniques that could enhance our understanding of the role mi RNAs play in HBV replication and HBV-associated disease, ultimately leading to new therapeutic options and improved patient outcomes. | Jason Lamontagne Laura F Steel Michael J Bouchard | 2015 | World Journal of Gastroenterology2015，21，24： | 17 |
| 12 | Findings from 2010 Global Adult Tobacco Survey: Implementation of MPOWER Policy in China显示文摘Objective To assess the implementation of five key tobacco control policies in China: protection from second-hand smoke (SHS); offering help to quit; health warnings regarding tobacco use; the enforcement of bans on tobacco advertising, promotion, and sponsorship; and increasing tobacco taxes and prices. Methods Using 2010 Global Adults Tobacco Survey in China (GATS-China), 10 indicators are used to assess the implementation of five key tobacco control policies of MPOWER in China. Results Overall, 63.3% and 72.7% of adultsnoticed people smoking indoor workplaces and public places, respectively. Approximately 60% of smokers were not asked about their smoking habits and approximately 67% were not advised to quit on their visit to a health worker. Sixty percent of adults noticed health warning messages on cigarette packaging and in the media in the last 30 days, 63.6% stated that they would not consider quitting. Twenty percent of respondents noticed tobacco advertising, promotion, and/or sponsorship activities in the 30 days prior to the survey. Among them, 76.3% noticed the direct advertising and 50% noticed from TV programs. Although purchasing price of one pack of cigarettes ranged from 1 to 200 RMB, 50% of current smokers (about 150 million) spent 5 RMB or less on one pack of cigarette. The expenditure on 100 packets of cigarettes represents 2% of 2009 GDP per capita. Conclusion The average score for the implementation of the 5 policies of MPOWER in China is 37.3 points, indicating tobacco control policies in China is poor and there is a large gaps from the FCTC requirements. | GONG-HUAN YANG QIANG LI CONG-XIAO WANG JASON HSIA YAN YANG LIN XIAO JIE YANG Lu-HUA ZHAO JIAN ZHANG LI XIE | 2010 | Biomedical and Environmental Sciences2010，23，6： | 16 |
| 13 | 南京市居民购物行为的影响因素和空间效应——基于四种商品的对比研究显示文摘信息技术的发展和使用不断改变着居民的购物方式和行为,并对城市交通和城市商业空间布局等产生了一系列影响。采用2015年南京市居民购物行为问卷调查数据,通过联合有序probit模型,探讨南京市居民购物行为影响因素和空间效应,并对四种商品进行对比研究。研究表明:(1)家庭生命周期、城市建成环境、居民购物态度、机动车保有状况和社会经济人口因素均对居民购物行为有显著影响,且存在产品类型差异;(2)不同类型人群对城市交通出行和商业布局的影响不同,且特征人群分布存在空间分异;(3)居民对不同产品类型购物的空间偏好存在差异,且这种偏好受居民主观决策和客观环境共同影响。基于以上发现,对城市交通和商业布局提出相关建议。 | 杜晓娟 甄峰 CAO Jason | 2017 | 地理研究2017，36，5： | 16 |
| 14 | Regulation of inflammation and tumorigenesis by the FIPE family of phospholipid transfer proteins显示文摘 | Jason R Goldsmith Youhai H Chen | 2017 | Cellular & Molecular Immunology2017，14，6： | 15 |
| 15 | 天然实验流域降雨径流现象发生的悖论显示文摘作为滁州水文实验系统一部分的1号天然实验流域,面积7897m2,以安山岩为基底,上覆平均厚度2.46m的第四系沉积物。实测了包括地面径流和地面下径流的各种降雨径流响应,后者包括来自非饱和带的壤中流和饱和带的地下水径流。表明这些径流成分有着复杂的组合类型,主要是以地面径流为主的SR型和以地面下径流为主的SSR型,以及中间的和演化的类型。SR型实例中的地面径流量可占总径流的65%,而SSR实例中的地面下径流量可有90%。主要降水的7月,地面下贡献占54.5%,其中地下水径流即占33%。大部分地面径流与降水的18O组成有不小的差异,比较了同时进行测验的3个实验流域,在1400min的降水径流过程中,降水的平均δ18O为-1.210%,而同期地面径流的平均δ18O,2号水文山流域(512m2)为-1.132%,1号南大洼天然流域为-1.065%,3号只有薄层风化碎屑的牵牛花流域(4573m2)为-0.801%。这质疑了现行同位素流量过程线划分方法8个假定中的两个:地面径流的同位素组成不同于降水,天然流域尤其如此;各种水源在汇集过程中的同位素分馏影响并非都可忽略不计。实验流域因降水而产生径流,但所产生的径流却有着非本次降水的组分,这一降水径流悖论发生于各个实验流域。SR型和SSR型总的非本次降水组分分别达16%和64%。 | 顾慰祖 尚熳廷 翟劭燚 陆家驹 Frentress Jason Jeffrey McDonnell Carol Kendall | 2010 | 水科学进展2010，21，4： | 15 |
| 16 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 17 | Portal hypertension: Imaging of portosystemic collateral pathways and associated image-guided therapy显示文摘Portal hypertension is a common clinical syndrome, defined by a pathologic increase in the portal venous pressure. Increased resistance to portal blood flow, the primary factor in the pathophysiology of portal hypertension, is in part due to morphological changes occurring in chronic liver diseases. This results in rerouting of blood flow away from the liver through collateral pathways to low-pressure systemic veins. Through a variety of computed tomographic, sonographic, magnetic resonance imaging and angiographic examples, this article discusses the appearances and prevalence of both common and less common portosystemic collateral channels in the thorax and abdomen. A brief overview of established interventional radiologic techniques for treatment of portal hypertension will also be provided. Awareness of the various imaging manifestations of portal hypertension can be helpful for assessing overall prognosis and planning proper management. | Murad Feroz Bandali Anirudh Mirakhur Edward Wolfgang Lee Mollie Clarke Ferris David James Sadler Robin Ritchie Gray Jason Kam Wong | 2017 | World Journal of Gastroenterology2017，23，10： | 14 |
| 18 | 变泥质岩的深熔作用与具铈(Ce)负异常熔体的成因显示文摘对美国加州南Sierra Nevada岩基中一个典型的中生代变质表壳岩及其混合岩带进行了详细的野外观察和元素地球化学研究。研究发现:在持久(约为150Ma)的花岗岩侵位作用下,早白垩世变泥质岩发生达角闪岩相的中高级变质作用和部分熔融,导致Isabella混合岩的形成;浅色体具有和变泥质岩及混合岩近平行的REE分布模式,但浅色体的LREE含量相对较低;和变泥质岩相似,混合岩中的浅色体具有显著的Ce负异常。野外观测、岩相观察及元素地球化学特征表明,浅色体显著的Ce负异常是继承了原岩的Ce负异常特征,而不是由于副矿物(磷灰石、独居石或锆石)的差异溶解或结晶分异作用造成的。早白垩世变泥质岩(浅色体的原岩)主要由泥质及沙质海相沉积物组成,局部夹基性火山灰和火山碎屑,形成于与大陆岛弧密切相关的浅海环境。原岩的Ce负异常反映了较还原的浅海沉积环境。具有Ce负异常浅色体的产出表明,如果俯冲带上的沉积岩在俯冲过程中发生部分熔融作用并且所产生的熔体参与大洋型岛弧岩浆作用,最终可以导致具有Ce异常的基性岩浆生成。 | 曾令森 Mihai DUCEA Jason SALEEBY | 2005 | 岩石矿物学杂志2005，24，5： | 14 |
| 19 | The human gut sterolbiome:bile acid-microbiome endocrine aspects and therapeutics显示文摘The human body is now viewed as a complex ecosystem that on a cellular and gene level is mainly prokaryotic. The mammalian liver synthesizes and secretes hydrophilic primary bile acids, some of which enter the colon during the enterohepatic circulation, and are converted into numerous hydrophobic metabolites which are capable of entering the portal circulation, returned to the liver, and in humans,accumulating in the biliary pool. Bile acids are hormones that regulate their own synthesis, transport, in addition to glucose and lipid homeostasis, and energy balance. The gut microbial community through their capacity to produce bile acid metabolites distinct from the liver can be thought of as an 'endocrine organ'with potential to alter host physiology, perhaps to their own favor. We propose the term 'sterolbiome' to describe the genetic potential of the gut microbiome to produce endocrine molecules from endogenous and exogenous steroids in the mammalian gut. The affinity of secondary bile acid metabolites to host nuclear receptors is described, the potential of secondary bile acids to promote tumors, and the potential of bile acids to serve as therapeutic agents are discussed. | Jason M.Ridlon Jasmohan S.Bajaj | 2015 | Acta Pharmaceutica Sinica B2015，5，2： | 14 |
| 20 | Prostate cancer in Asia:A collaborative report显示文摘The incidence of prostate cancer(PCa)within Asian population used to be much lower than in the Western population;however,in recent years the incidence and mortality rate of PCa in some Asian countries have grown rapidly.This collaborative report summarized the latest epidemiology information,risk factors,and racial differences in PCa diagnosis,current status and new trends in surgery management and novel agents for castration-resistant prostate cancer.We believe such information would be helpful in clinical decision making for urologists and oncologists,health-care ministries and medical researchers. | Rui Chen Shancheng Ren 无 Ming Kwong Yiu Ng Chi Fai Wai Sam Cheng Lap Hong Ian Seiji Naito Tadashi Matsuda Elijah Kehinde Ali Kural Jason Yichun Chiu Rainy Umbas Qiang Wei Xiaolei Shi Liqun Zhou Jian Huang Yiran Huang Liping Xie Lulin Ma Changjun Yin Danfeng Xu Kexin Xu Zhangqun Ye Chunxiao Liu Dingwei Ye Xin Gao Qiang Fu Jianquan Hou Jianlin Yuan Dalin He Tiejun Pan Qiang Ding Fengshuo Jin Benkang Shi Gongxian Wang Xiuheng Liu Dongwen Wang Zhoujun Shen Xiangbo Kong Wanhai Xu Yaoliang Deng Haibo Xia Alexa NCohen Xu Gao Chuanliang Xu Yinghao Sun | 2014 | Asian Journal of Urology2014，1，1： | 13 |
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