5篇
您的检索式：作者名="Jason Barnes"
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| 1 | 轮胎未来发展趋势的研究显示文摘 | Jason Barnes 张学山 | 2003 | 轮胎工业2003，23，12： | 3 |
| 2 | Predicting outcome after cardiac surgery in patients with cirrhosis: A comparison of Child-Pugh and MELD scores显示文摘 | Amitabh Suman David S. Barnes Nizar N. Zein Gavin N. Levinthal Jason T. Connor William D. Carey | 2004 | Clinical Gastroenterology and Hepatology2004，，8： | 1 |
| 3 | 有请新老板显示文摘90年代的流行文化包罗万象,喜气洋洋。情况或许有点吵吵闹闹,包容性却无容置疑。汽车方面也是一样,既有斯巴鲁祭出ImperzaTurbo号令天下,促成科林·麦克雷(Colin McRae)横扫江湖,在世界拉力舞台大放异彩,与此同时又有一位NPeterWheeler的前ICI工程师扭尽六壬,把一家剑走偏锋的英国汽车公司变成世界级劲旅。 | JASON BARLOW TOM BARNES TONY | 2017 | 汽车测试报告2017，0，12： | 0 |
| 4 | Non-severe burn injury increases cancer incidence in mice and has long-term impacts on the activation and function of T cells显示文摘Background:Recent evidence suggests that burn patients are at increased risk of hospital admission for infection,mental health conditions,cardiovascular disease and cancer for many years after discharge for the burn injury itself.Burn injury has also been shown to induce sustained immune system dysfunction.This change to immune function may contribute to the increased risk of chronic disease observed.However,the mechanisms that disrupt long-term immune function in response to burn trauma,and their link to long-term morbidity,remain unknown.In this study we investigated changes to immune function after burn injury using a murine model of non-severe injury.Methods:An established mouse model of non-severe burn injury(full thickness burn equivalent to 8%total body surface area)was used in combination with an orthotopic model of B16 melanoma to investigate the link between burns and cancer.Considering that CD8^(+)T cells are important drivers of effective tumour suppression in this model,we also investigated potential dysregulation of this immune population using mouse models of burn injury in combination with herpes simplex virus infection.Flow cytometry was used to detect and quantify cell populations of interest and changes in immune function.Results:We demonstrate that 4 weeks after a non-severe burn injury,mice were significantly more susceptible to tumour development than controls using an orthotopic model of B16 melanoma.In addition,our results reveal that CD8^(+)T cell expansion,differentiation and memory potential is significantly impaired at 1 month post-burn.Conclusions:Our data suggests that CD8^(+)T cell-mediated immunity may be dysfunctional for a sustained period after even non-severe burn injury.Further studies in patients to validate these findings may support clinical intervention to restore or protect immunity in patients after burn injury and reduce the increased risk of secondary morbidities observed. | Lucy W.Barrett Vanessa S.Fear Bree Foley Katherine Audsley Samantha Barnes Hannah Newnes Alison McDonnell Fiona M.Wood Mark W.Fear Jason Waithman | 2022 | Burns & Trauma2022，10，1： | 0 |
| 5 | 深度冻结的地球显示文摘克里斯蒂安·惠更斯于1655年发现了第一颗环绕土星运行的卫星。之后,几代科学家们都试图对第六颗土星卫星——土卫六这个命名为“泰坦”的遥远世界取得更多了解。在最初发现时,人们就知道它的尺寸和特征更加接近一颗行星。泰坦的直径达5150千米,要比月球大一半以上,它的尺寸甚至超过了水星。没有任何其它卫星能像泰坦那样拥有如此稠密的大气层,何况其主要成分是氮,并含有甲烷——事实上,行星专家们将泰坦视为被深度冻结的原始地球。 | Jason Barnes 卢克(译) | 2008 | 中国国家天文2008，，12： | 0 |
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