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| 1 | Biliary carcinoembryonic antigen levels in diagnosis of occult hepatic metastases from colorectal carcinoma显示文摘AIM: To prospectively explore the role of carcinoembryonic antigen (CEA) in gallbladder bile in patients with colorectal carcinoma and the morphological and clinical features of neoplasia and the occurrence of hepatic metastases.METHODS: CEA levels in the gallbladder and peripheral blood were studied in 44 patients with colorectal carcinoma and 10 patients with uncomplicated cholelithiasis. CEA samples were collected from the gallbladder bile and peripheral blood during the operation, immediately before extirpating the colorectal neoplasia or cholecystectomy.Values of up to 5 ng/ml were considered normal for bile and serum CEA.RESULTS: In the 44 patients with colorectal carcinoma who underwent operation with curative intent, the average level of serum CEA was 8.5 ng/ml (range: 0.1 to 111.0 ng/ml) and for bile CEA it was 74.5 ng/ml (range: 0.2 to 571.0ng/ml). In the patients with uncomplicated cholelithiasis who underwent cholecystectomy, the average level of serum CEA was 1.9 ng/ml (range: 1.0 to 3.5 ng/ml) and for bile CEA it was 1.2 ng/ml (range: 0.3 to 2.9 ng/ml).The average duration of follow-up time was 16.5 months (range: 6 to 48 months). Four patients who underwent extirpation of the colorectal carcinoma without evidence of hepatic metastasis and with an average bile CEA value of 213.2 ng/ml presented hepatic metastases between three and seventeen months after removal of the primary colorectal neoplasia. Three of them successfully underwent extirpation of the hepatic lesions.CONCLUSION: High CEA levels in gallbladders of patients undergoing curative operation for colorectal carcinoma may indicate the presence of hepatic metastases. Such patients must be followed up with special attention to the diagnosis of such lesions. | Jaques Waisberg Rogério T.Palma Luís Contim Neto Lourdes C.Martins Maurício S.L.Oliveira Carlos A. Nagashima Antonio C.Godoy Fabio S.Goffi | 2003 | World Journal of Gastroenterology2003，9，7： | 5 |
| 2 | Nickel sulphide deposits in Australia: characteristics, resources and potential显示文摘 | Hoatson D M Jaireth S Jaques A L | 2006 | Ore Geology Reviews2006，29，： | 1 |
| 3 | Generative feature-based design-by-constraints as a means of integration witnin the manufacture industry显示文摘 | Jaques M W S Billingsley J Harrison D | 1991 | Compuer-Aided Engineering Journal1991，8，6： | 1 |
| 4 | Nickel sulfide deposit in Australia:Characteristics,resources,and potential显示文摘 | Hoatson D M Jaireth S and Jaques A L | 2006 | Ore Geolo- gy Review2006，29，34： | 1 |
| 5 | Collection of peripheral blood progenitor cells on Day 4 is feasible and effective while reducing granulocyte- colony- stimulating factor exposure to healthy donors 显示文摘 | Flommersfeld S Sohlbaeh K Jaques G | 2015 | Transfusion2015，55，6： | 1 |
| 6 | Cardiotmphinl protects beta cells from apoptosis and prevents streptozotocin - induced diabetes in a mouse model 显示文摘 | Jimnez - Gonzalez M Jaques F Redrfguez S | 2013 | Diabetologia2013，56，4： | 1 |
| 7 | Indoor-outdoor air pollution relations: particulate matter less than 10 mm in aerodynamic diameter ( PM10 ) in the homes of asthmatics 显示文摘 | Colome S D Kado N Y Jaques P | 1992 | Atmospheric Environment1992，26，： | 1 |
| 8 | Three new regulators of swarming in Vbrio parahaemolyticus显示文摘 | Jaques S Mccarter LL | 2006 | J Bacteriol2006，188，7： | 1 |
| 9 | Differential expression of iodothyronine deiodinase type 2 in growth plates of chickens divergently selected for incidence of tibial dyschondroplasia显示文摘 | Shen S Berry W Jaques S | 2004 | Anim Genet2004，35，2： | 1 |
| 10 | Synthesis of uranium nitride by a mechanically in duced gas-solid reaction显示文摘 | JAQUES B MARX B HAMDY A S | 2008 | Journal of Nuclear Materials2008，381，： | 1 |
| 11 | Cardiotrophin 1 protects beta ceils from apoptosis and prevents streptozotocin-induced diabetes in a mouse model显示文摘 | Jimnez-Gonz61ez M Jaques F Rodriguez S | 2013 | Diabetologia2013，56，4： | 1 |
| 12 | Acclimatization of soil respiration to warming in a tall grass prairie 显示文摘 | Kim S Jaques P A Chang M Froines J R Sioutas C | 2001 | Nature2001，413，6856： | 1 |
| 13 | Energy and environmental implications of copper production显示文摘 | Alvarado S Maldonado P Jaques I | 1999 | Energy1999，24，4： | 1 |
| 14 | Fast - track management of patients undergoing proximal pancreatic resection 显示文摘 | French J J Mansfield S D Jaques K | 2009 | Ann R Coil Surg Engl2009，91，3： | 1 |
| 15 | Neuroendocrine gastric carcinoma expressing somatostatin: A highly malignant, rare tumor显示文摘,糟糕区分了胃的神经内分泌癌稀罕,值得特别注意,,他们是好攻击的并且有极其差的预后。在这份报告,我们与很快致命的结果描述胃的神经内分泌癌。resected 标本染色的 Immunohistological 表明肿瘤是内分泌的癌。肿瘤揭示了强烈免疫反应到 pan-neuroendocrine 标记和弥漫的 somatostatin 免疫反应。与 von Recklinghausen 的神经纤维瘤病没有 psammoma 和没有可论证的协会。在胃肠道,主要生产 somatostatin 的神经内分泌肿瘤仅仅在十二指肠被描述了。就我们的知识而言,现在的报告是广泛地表示 somatostatin 为唯一的神经内分泌的规章的肽的神经内分泌的胃的癌的第二份病案报告。 | Jaques Waisberg Leandro Luongo de Matos Ana Maria do Amaral Antonio Mader Sérgio Pezzolo Esmeralda Miristene Eher Vera Luiza Capelozzi Manlio Basilio Speranzini | 2006 | World Journal of Gastroenterology2006，12，24： | 1 |
| 16 | Three Monte Carlo programs of polarized light transport into scattering media显示文摘 | Ramella-Roman J C Prahl S A Jaques S L | 2005 | Optics Express2005，13，12： | 1 |
| 17 | Preterm birth,ovarian endometriomata, and assisted reproduction technologies显示文摘 | Femando S Breheny S Jaques AM | 2009 | Fertil Steril2009，91，2： | 1 |
| 18 | Three new regulators of swarming in Vibrio parahaemolyticus 显示文摘 | Jaques S McCarter LL | 2006 | J Bacteriol2006，188，7： | 1 |
| 19 | The Endowment Effect and the Coase Theorem显示文摘 | Jaques S | 1992 | American Journal of Agricultural Economics1992，，74： | 1 |
| 20 | Mutations conferring resistance to phenamil and amiloride,inhibitors of sodium-driven motility of Vibrio parahaemolyticus显示文摘 | Kim YK McCarter LL | 1999 | Proc Natl Acad Sci USA1999，96，8： | 1 |
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