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	题名	作者	年代	出处	被引量
1	Protective effect of ascorbic acid in experimental gastric cancer: reduction of oxidative stress显示文摘AIM: Oxidative stress participates in the cell carcinogenesis by inducing DNA mutations. Our aim was to assess whether ascorbic acid, an antioxidant, could have a role in preventing ROS (Reactive Oxygen Species) generation in experimental gastric carcinoma in a rat model.METHODS: Experimental gastric cancer was induced in twelve Wistar male rats (weighting 250-350 g) by profound duodeno-gastric reflux throught split gastrojenunostomy. The rats were allocated to the following groups: Group Ⅰ (n=6)was the control; Group Ⅱ (n=6) which was mantained with daily intake of tape water with Vitamin C (30 mg/Kg). After 6 or 12 months, samples of gastric tumor or non tumor mucosa were taken from the anastomosis of both groups.Oxidative stress was measured by superoxide quantification through lucigenin-amplified chemiluminescence base and by staining with Nitrobluetetrazolium. The histopathologic confirmation of adenocarcinoma was made by eosinhemathoxilin method.RESULTS: The intestinal type of gastric adenocarcinoma was microscopically identified in all animals of group Ⅰwhereas only 3 rats of group Ⅱ showed an adenocarcinoma without macroscopic evidence of them. The cancers were located in the anastomosis in all cases. Basal luminescence from tumor gastric tissue generated 38.4±6.8 count per minute/mg/x106 (mean±SD) and 14.9±4.0 count per minute/mg/×106, respectively, in group Ⅰ and Ⅱ animals (P<0.05). The Nitrobluetetrazolium method showed intense staining in tumor tissues but not in non neoplasic mucosa.CONCLUSION: Experimental gastric tumors seem to produce more reactive oxygen species than non neoplasic gastric tissue. The reduction of oxidative stress and gastric tumor incidence in rats were induced by the intake of ascorbic acid. Therefore, it may have a role in the prevention of gastric carcinoma.	Claudia P.M.S.Oliveira Paulo Kassab Fabio P.Lopasso Heraldo P.Souza Mariano Janiszewski Francisco R.M.Laurindo Kioshi Iriya Antonio A.Laudanna	2003	World Journal of Gastroenterology2003，9，3：	2
2	The influence of filler modification on its aggregation and dispersion behaviour in silica/PBT composite显示文摘	Jesionowski T Bula K Janiszewski J	2003	Composite Interfaces2003，10，23：	1
3	The influence of avatars on online consumer shopping behavior 显示文摘	Martin Holzwarth Chris Janiszewski and Marcus M Neumann	2006	Journal of Marketing2006，70，10：	1
4	The influence of display characteristics on visual exploratory search behavior 显示文摘	Janiszewski C	1998	Journal of Consumer Research1998，25，3：	1
5	A high-capacity LC/MS system for the bioanalysis of samples generated from plate-based metabolic screening显示文摘	Janiszewski J S Rogers K J Whalen K M Cole M J Liston T E Duchoslav E	2001	Anal Chem2001，73，：	1
6	Mast cell ionic channels: significance for stimulus-secretion coupling 显示文摘	Janiszewski J Huizinga JD Blennerhassett MG	1992	Can J Physiol Pharmacol1992，70，1：	1
7	Interactive home shopping: Consumer, retailer, and manufacturer incentives to participate in electronic marketplaces显示文摘	Alba Joseph John Lynch Barton Weitz Chris Janiszewski Richard Lutz Alan Sawyer and Stacy Wood	1997	Journal of Marketing1997，61，：	1
8	The influence of display characteristics on visual exploratory search behavior 显示文摘	Janiszewski C	1998	Journal of Consumer Research1998，25，3：	1
9	When are broader brands stronger brands? An accessibility perspective on the success of brand extensions显示文摘	Meyvis T Janiszewski C		0，，02：	1
10	Two ways of learning brand association 显示文摘	Ossleaer Janiszewski	2001	Journal of consumer arch2001，，9：	1
11	Inhibition of vascular NADH/NADPH oxidase activity by thiol reagents:lack of correlation with cellular glutathione redox status显示文摘	Janiszewski M Pedro MA Scheffer RC	2000	Free Radic Biol Med2000，29，9：	1
12	Numerically controlled oscillators with hybrid function generators显示文摘	Janiszewski I Hoppe B Meuth H	2002	IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control2002，49，7：	1
13	Physical activity in the treatment of obesity: beyond body weight reduction 显示文摘	Janiszewski PM Ross R	2007	Appl Physiol Nutr Metab2007，32，：	1
14	Platelet-derived exosomes of septic individuals possess proapoptotic NAD(P)H oxidase activity: A novel vascular redox pathway显示文摘	Mariano Janiszewski Alípio O. do Carmo Marcelo A. Pedro Eliézer Silva Elias Knobel Francisco R. M. Laurindo	2004	Critical Care Medicine2004，，3：	1
15	Caspases and their role in gastric cancer显示文摘	Frejlich E Rudno-Rudzińska J Janiszewski K	2013	Adv Clin Exp Med2013，22，4：	1
16	Inhibition of vascular NADH/NADPH oxidase activity by thiol reagents:lack of correlation with cellular glutathione redox status显示文摘	Janiszewski M Pedro MA Scheffer RC	2000	Free Radic Biol Med2000，29，9：	1
17	The Influ- ence of Macro-Level Motives on Consideration Set Composition in Novel Purchase Situations 显示文摘	CHAKRAVARTI A JANISZEWSKI C	2003	Jour- nal of Consumer Research2003，30，2：	1
18	Lightning-induced volt- ages on overhead lines-application of the extended Rusck model显示文摘	PIANTINI A JANISZEWSKI J M	2009	IEEE Transactions on Electromagnetic Compati- bility2009，51，3：	1
19	Work or fun? How task construal and completion influence regulatory behavior显示文摘	Laran J and Janiszewski C	2011	Journal of Consumer Research2011，37，6：	1
20	Platelet derived exosomes of septic individuals possess proapoptotic NAD(P) H oxidase activity: A novel vascular redox pathway 显示文摘	Janiszewski M Do Carmo AO Pedro MA	2004	Crit Care Med2004，32，81：	1

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