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| 1 | Epidemiology of perforated peptic ulcer:Age-and gender-adjusted analysis of incidence and mortality显示文摘AIM:To investigate the epidemiological trends in inci-dence and mortality of perforated peptic ulcer(PPU)in a well-defined Norwegian population. METHODS:A retrospective,population-based,single-center,consecutive cohort study of all patients diag-nosed with benign perforated peptic ulcer.Included were both gastric and duodenal ulcer patients admitted to Stavanger University Hospital between January 2001 and December 2010.Ulcers with a malignant neoplasia diagnosis,verified by histology after biopsy or resection,were excluded.Patients were identified from the hospitals administrative electronic database using pertinent ICD-9 and ICD-10 codes(K25.1,K25.2,K25.5, K25.6,K26.1,K26.2,K26.5,K26.6).Additional searches using appropriate codes for relevant laparoscopic and open surgical procedures(e.g.,JDA 60,JDA 61,JDH 70 and JDH 71)were performed to enable a complete identification of all patients.Patient demographics,presentation patterns and clinical data were retrieved from hospital records and surgical notes.Crude and adjusted incidence and mortality rates were estimated by using national population demographics data. RESULTS:In the study period,a total of 172 patients with PPU were identified.The adjusted incidence rate for the overall 10-year period was 6.5 per 100 000 per year(95%CI:5.6-7.6)and the adjusted mortality rate for the overall 10-year period was 1.1 per 100 000 per year(95%CI:0.7-1.6).A non-significant decline in ad-justed incidence rate from 9.7 to 5.6 occurred during the decade.The standardized mortality ratio for the whole study period was 5.7(95%CI:3.9-8.2),while the total 30-d mortality was 16.3%.No difference in in-cidence or mortality was found between genders.However,for patients≥60 years,the incidence increased over 10-fold,and mortality more than 50-fold,compared to younger ages.The admission rates outside office hours were high with almost two out of three(63%) admissions seen at evening/night time shifts and/or during weekends.The observed seasonal variations in admissions were not statistically significant. CONCLUSION:The adjusted incidence rate,seasonal distribution and mortality rate was stable.PPU fre-quently presents outside regular work-hours.Increase in incidence and mortality occurs with older age. | Kenneth Thorsen Jon Arne Sreide Jan Terje Kvaly Tom Glomsaker Kjetil Sreide | 2013 | World Journal of Gastroenterology2013，19，3： | 14 |
| 2 | A practical(t,n) multi secret sharing scheme显示文摘 | Chien H Y Jan J K Tseng Y M | 2000 | IEICE Transactions on Fundamentals2000，83，12： | 1 |
| 3 | Ha - rasval 12 oncogene increases susceptibility of NIH/3T3 cells to lovastatin显示文摘 | CHANG M Y JAN M S WAN S J | 1998 | Biochem Biophys Res Commun1998，，： | 1 |
| 4 | Molecular cytogenetics of ovarian granulosa cell tumors by comparative genomic hybridization 显示文摘 | Lin YS Eng H Jan Y | 1995 | Gyn Oncol1995，97，1： | 1 |
| 5 | Hepatitis B virus surface antigen can activate human monocyte-derived dendritic cells by nuclear factor kappa B and p38 mitogen-activated protein kinase medi- ated signaling显示文摘 | Jan R H Lin Y L Chen C J | 2012 | Microbiol Immunol2012，5610，： | 1 |
| 6 | Finding the most vital edge with respect to minimum spanning tree in weighted graphs显示文摘 | Hsu L H Jan R H Lee Y C | 1991 | Information Processing Letters1991，39，1： | 1 |
| 7 | Molecular basis for K(ATP) assembly: transmembrane interactions mediate association of a K+ channel with an ABC transporter 显示文摘 | Schwappach B Zerangue N Jan Y N | 2000 | Neuron2000，26，： | 1 |
| 8 | A Practical (t, n) Multi-secret Sharing Scheme 显示文摘 | Chien H Y JAN J K Tseng Y M | 2000 | IEICE Trans on Fundamentals2000，83，12： | 1 |
| 9 | The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse an human livermicrosomes显示文摘 | Ueng Y F Jan W C Lin L C | 2002 | Drug Metab Dispos2002，30，3： | 1 |
| 10 | Fabrication of Fe-Si-B based amorphous powder cores by cold pressing and their magnetic properties显示文摘 | Kim Y B Jans D H Seok H K | | 0，，： | 1 |
| 11 | A mobile ticket system based on personal trusted device显示文摘 | CHEN Y Y CHEN C L JAN J K | 2007 | Wireless Personal Communications2007，40，4： | 1 |
| 12 | Baubion Netude de 1'action chronotrope del'ATP Chezl'homme显示文摘 | Hughes Fc Jan Y Bors V | 1980 | Coer Med intern1980，19，： | 1 |
| 13 | A peptide as a possible transmitter in sympathetic ganglia of the frog显示文摘 | Jan Y N Jan L Y Kuffler S W | 1979 | Proc Natl Acad Sci USA1979，76，3： | 1 |
| 14 | A linearly adaptive gate drive technique for light-load efficiency 显示文摘 | LIU P-J JAN Y CHEN E | 2009 | International Journal of Circuit Theory and Applications2009，37，10： | 1 |
| 15 | PhaseⅢ study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma: positive effect on overall and progression-free survival 显示文摘 | Lin J C Jan J S Hsu C Y | 2003 | J Clin Oncol2003，21，4： | 1 |
| 16 | A DC-DC charge pump design based on voltage doublers显示文摘 | Starzyk J A Jan Y W Qiu F J | 2001 | IEEE Trans on Circuit Syst I2001，48，： | 1 |
| 17 | On the security of generalization of threshold signature and authenticated encryption显示文摘 | TSENG Y M JAN J K CHIEN H Y | 2001 | IEICE Transactions on Fundamentals2001，84，10： | 1 |
| 18 | Structural analysis and proteolytic processing of recombinant G domain of mouse laminin α2 chain显示文摘 | Jan F T Karlheinz Yoshihiko Y | 1998 | FEBS letters1998，426，： | 1 |
| 19 | A practical (t,n) multi-secret sharing scheme显示文摘 | CHIEN H Y JAN J K TSENG Y M | 2000 | IEICE Trans on Fundamentals2000，83，12： | 1 |
| 20 | Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute re- spiratory syndrome coronavirus 显示文摘 | Wen C C Kuo Y H Jan J T | 2007 | J Med Chem2007，50，17： | 1 |
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