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| 1 | 受访者推动抽样:研究隐藏人口的方法与实践显示文摘“隐藏人口”的特点是规模较小且成员一般不愿暴露身份,因此很难使用常规抽样方法对其进行研究。近年来出现了一种新的研究隐藏人口的方法——受访者推动抽样(RDS)方法,该方法在传统“雪球抽样”方法的基础上,结合社会网络分析的理论和方法,使研究者有可能根据样本对总体特征做出合理的推论。本文对RDS方法的理论渊源、基本思路、主要操作步骤和原理进行了简要介绍,并探讨了在实际操作过程中应注意的问题。 | 赵延东 Jon Pedersen | 2007 | 社会2007，27，2： | 44 |
| 2 | Progress in additive manufacturing on new materials: A review显示文摘Recent efforts and advances in additive manufacturing(AM) on different types of new materials are presented and reviewed. Special attention is paid to the material design of cladding layers, the choice of feedstock materials, the metallurgical behavior and synthesis principle during the AM process, and the resulted microstructures and properties, as well as the relationship between these factors. Thereafter,the trend of development in the future is forecasted, including: Effects of the particles size and size distribution of powders; Approaches for producing fine microstructures; Opportunities for creating new materials by AM; Wide applications in reconditioning of damaged components; Challenges for deep understanding and applications of the AMed new materials. The idea of 'Develop Materials' or 'Create Materials' by AM is highlighted, but a series of scientific, technological and engineering problems remain to be solved in future. | Neng Li Shuai Huang Guodong Zhang Renyao Qin Wei Liu Huaping Xiong Gongqi Shi Jon Blackburn | 2019 | Journal of Materials Science & Technology2019，35，2： | 47 |
| 3 | 3D bioactive composite scaffolds for bone tissue engineering显示文摘Bone is the second most commonly transplanted tissue worldwide,with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.However,significant limitations affect current treatment options and clinical demand for bone grafts continues to rise due to conditions such as trauma,cancer,infection and arthritis.Developing bioactive three-dimensional(3D)scaffolds to support bone regeneration has therefore become a key area of focus within bone tissue engineering(BTE).A variety of materials and manufacturing methods including 3D printing have been used to create novel alternatives to traditional bone grafts.However,individual groups of materials including polymers,ceramics and hydrogels have been unable to fully replicate the properties of bone when used alone.Favourable material properties can be combined and bioactivity improved when groups of materials are used together in composite 3D scaffolds.This review will therefore consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers,hydrogels,metals,ceramics and bio-glasses in BTE.Scaffold fabrication methodology,mechanical performance,biocompatibility,bioactivity,and potential clinical translations will be discussed. | Gareth Turnbull Jon Clarke Frederic Picard Philip Riches Luanluan Jia Fengxuan Han Bin Li Wenmiao Shu | 2018 | Bioactive Materials2018，3，3： | 40 |
| 4 | 中国成人的卷烟需求及影响因素研究显示文摘本文全面讨论了我国成人对卷烟的需求状况及其影响因素 ,测算了总体居民的卷烟需求的价格弹性 (- 0 5 13)和不同收入群体的价格弹性 :贫困组为 - 1 90 6 ,低收入组为 - 0 774 ,高收入组为- 0 5 0 7;男性组为 - 0 4 5 ,女性组为 - 0 6 9。 | 毛正中 杨功焕 马继民 Jon Samet Marion Ceraso | 2003 | 卫生软科学2003，17，2： | 28 |
| 5 | 美国结直肠外科医师协会2019版藏毛窦诊治临床实践指南显示文摘美国结直肠外科医师协会(The American Society of Colon and Rectal Surgeons,ASCRS)于2019年2月公布了最新的藏毛窦诊治临床实践指南。指南是由国际知名结直肠外科专家组成的临床实践指南委员会修订,对藏毛窦的一些争议进行了汇总和分析。 | Eric K.Johnson,M.D. Jon D.Vogel,M.D. Michelle L.Cowan,M.D. Daniel L.Feingold,M.D. Scott R.Steele,M.D.,M.B.A. 杜涛 张振宇 冷株赟 傅传刚 | 2019 | 结直肠肛门外科2019，25，4： | 23 |
| 6 | The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters显示文摘最近的研究在众多的生物过程增加了我们长 noncoding RNA (lncRNAs ) 的理解,但是很少在体的房间 reprogramming 检验了他们的角色。通过表示介绍并且功能的屏蔽,我们鉴别了大 intergenic noncoding RNA p21 (lincRNA-p21 ) 损害 reprogramming。尤其是, lincRNA-p21 被 p53 导致,但是不在 reprogramming 支持 apoptosis 或房间老朽。相反, lincRNA-p21 与 H3K9 methyltransferase SETDB1 和维护 DNA methyltransferase DNMT1 联系,它被 RNA 有约束力的蛋白质 HNRNPK 便于。因而, lincRNA-p21 由在 pluripotency 基因倡导者支撑 H3K9me3 或 CpG methylation 阻止 reprogramming。我们的结果在 reprogramming 提供卓见进 lncRNAs 的角色并且建立在 p53 和 heterochromatin 规定之间的一个新奇连接。 | Xichen Bao Haitao Wu Xihua Zhu Xiangpeng Guo Andrew P Hutchins Zhiwei Luo Hong Song Yongqiang Chen Keyu Lai Menghui Yin Lingxiao Xu Liang Zhou Jiekai Chen Dongye Wang Baoming Qin Jon Frampton Hung-Fat Tse Duanqing Pei Huating Wang Biliang Zhang Miguel A Esteban | 2015 | Cell Research2015，25，1： | 21 |
| 7 | Sediment fingerprinting in fluvial systems:review of tracers,sediment sources and mixing models显示文摘Suspended sediments in fluvial systems originate from a myriad of diffuse and point sources,with the relative contribution from each source varying over time and space.The process of sediment fingerprinting focuses on developing methods that enable discrete sediment sources to be identified from a composite sample of suspended material.This review identifies existing methodological steps for sediment fingerprinting including fluvial and source sampling,and critically compares biogeochcmical and physical tracers used in fingerprinting studies.Implications of applying different mixing models to the same source data are explored using data from 41 catchments across Europe,Africa,Australia,Asia,and North and South America.The application of seven commonly used mixing models to two case studies from the US(North Fork Broad River watershed) and France(BIcone watershed) with local and global(genetic algorithm) optimization methods identified all outputs remained in the acceptable range of error defined by the original authors.We propose future sediment fingerprinting studies use models that combine the best explanatory parameters provided by the modified Collins(using correction factors) and Hughes(relying on iterations involving all data,and not only their mean values) models with optimization using genetic algorithms to best predict the relative contribution of sediment sources to fluvial systems. | Arman HADDADCHI Darren S.RYDER Olivier EVRARD Jon OLLEY | 2013 | International Journal of Sediment Research2013，28，4： | 14 |
| 8 | Epidemiology of perforated peptic ulcer:Age-and gender-adjusted analysis of incidence and mortality显示文摘AIM:To investigate the epidemiological trends in inci-dence and mortality of perforated peptic ulcer(PPU)in a well-defined Norwegian population. METHODS:A retrospective,population-based,single-center,consecutive cohort study of all patients diag-nosed with benign perforated peptic ulcer.Included were both gastric and duodenal ulcer patients admitted to Stavanger University Hospital between January 2001 and December 2010.Ulcers with a malignant neoplasia diagnosis,verified by histology after biopsy or resection,were excluded.Patients were identified from the hospitals administrative electronic database using pertinent ICD-9 and ICD-10 codes(K25.1,K25.2,K25.5, K25.6,K26.1,K26.2,K26.5,K26.6).Additional searches using appropriate codes for relevant laparoscopic and open surgical procedures(e.g.,JDA 60,JDA 61,JDH 70 and JDH 71)were performed to enable a complete identification of all patients.Patient demographics,presentation patterns and clinical data were retrieved from hospital records and surgical notes.Crude and adjusted incidence and mortality rates were estimated by using national population demographics data. RESULTS:In the study period,a total of 172 patients with PPU were identified.The adjusted incidence rate for the overall 10-year period was 6.5 per 100 000 per year(95%CI:5.6-7.6)and the adjusted mortality rate for the overall 10-year period was 1.1 per 100 000 per year(95%CI:0.7-1.6).A non-significant decline in ad-justed incidence rate from 9.7 to 5.6 occurred during the decade.The standardized mortality ratio for the whole study period was 5.7(95%CI:3.9-8.2),while the total 30-d mortality was 16.3%.No difference in in-cidence or mortality was found between genders.However,for patients≥60 years,the incidence increased over 10-fold,and mortality more than 50-fold,compared to younger ages.The admission rates outside office hours were high with almost two out of three(63%) admissions seen at evening/night time shifts and/or during weekends.The observed seasonal variations in admissions were not statistically significant. CONCLUSION:The adjusted incidence rate,seasonal distribution and mortality rate was stable.PPU fre-quently presents outside regular work-hours.Increase in incidence and mortality occurs with older age. | Kenneth Thorsen Jon Arne Sreide Jan Terje Kvaly Tom Glomsaker Kjetil Sreide | 2013 | World Journal of Gastroenterology2013，19，3： | 14 |
| 9 | 云南思茅地区新生代的持续旋转显示文摘新生代早期(约45 Ma),印度板块在经历了长时期的北向漂移后终与欧亚大陆碰撞。其后,以印度洋的扩张作用为驱动力,印度板块持续向欧亚大陆推挤,使造山带地区产生大规模的陆壳缩短,造就了壮观的世界屋脊——青藏高原。70年代中期。 | 陈海泓 郝杰 Jon P.Dobson Friedrich Heller Kennech J.Hsū | 1993 | 科学通报1993，38，24： | 13 |
| 10 | A prospective analysis of factors that influence weight loss in patients undergoing radiotherapy显示文摘Malnutrition occurs frequently in patients with cancer.Indeed,a variety of nutritional and tumorrelated factors must be taken into account in these patients.Recognizing this relationship,we aimed to prospectively evaluate the risk factors that influence weight loss in patients undergoing radiotherapy with oral nutritional supplementation and dietetic counseling.Weight loss of 74 patients during radiotherapy and 1 month after treatment was analyzed.Parameters such as age,gender,tumor location,tumor stage,Eastern Cooperative Oncology Group performance status(ECOG PS)score,and the use of chemotherapy were analyzed to evaluate their influence on weight loss.All patients underwent oral nutritional supplementation and dietetic counseling.Forty-six(65.7%)patients lost weight,with a mean weight loss of(4.73±3.91)kg,during radiotherapy.At 1 month after treatment,45(66.2%)patients lost weight,presenting a mean weight loss of(4.96±4.04)kg,corresponding to a(6.84±5.24)%net reduction from their baseline weight.Head and neck cancer patients had a mean weight loss of(3.25±5.30)kg,whereas the remaining patients had a mean weight loss of(0.64±2.39)kg(P=0.028)during radiotherapy.In the multivariate analysis,the head and neck tumor location(P=0.005),use of chemotherapy(P=0.011),and ECOG PS score of 2-3(P=0.026)were considered independent risk factors.Nutritional status and parameters,such as tumor location(especially the head and neck),the use of chemotherapy,and the ECOG PS score,should be evaluated before radiotherapy because these factors can influence weight loss during radiotherapy and 1 month after treatment. | Jon Cacicedo Francisco Casquero Lorea Martinez-Indart Olga del Hoyo Alfonso Gomez de Iturriaga Arturo Navarro Pedro Bilbao | 2014 | Chinese Journal of Cancer2014，33，4： | 12 |
| 11 | Rectal nitric oxide as biomarker in the treatment of inflammatory bowel disease: Responders versus nonresponders显示文摘瞄准:探索直肠的氮的氧化物(没有) 作为处理的简历标记,在 ulcerative (UC ) 和 Crohn 的反应是疾病(CD ) ,并且检验在之间的关系直肠没有,没有 synthases (NOS ) 的粘膜表示,和支持 inflammatory cytokines。方法:有 UC 的 22 个病人并且 24 在类固醇治疗期间与 CD 被监视。直肠没有层次被测量,临床的活动在天被估计 1, 3, 7 和 28。NOS 和支持 inflammatory cytokines 的粘膜存在被免疫组织化学和 RT-PCR 分析。结果:显著地显示的活跃 UC 和 CD 增加了直肠没有层次(10950 +/- 1280 每十亿分开的 7610 和 5040 +/-(ppb ) ,分别地) 作为与控制相比(154 +/- 71 ppb, P <
0.001 ) 。直肠不在 UC 和 CD 与疾病活动微弱地相关(r = 0.34 为 UC 和 r = 0.48 为 CD, P <
0.01 ) 。在 12 个病人,一堂类固醇倔强的功课导致了结肠切除术。仅仅稍微有的这些病人没增加层次(UC:620 +/- 270 ppb;CD:1260 +/- 550 ppb ) 与那些相比与治疗学的回答(UC:18860 +/- 530 ppb, P <
0.001;CD:10060 +/- 3200 ppb, P <
0.05 ) 。结论:直肠没有水平是在是的 IBD 的治疗反应的一个有用简历标记低没有层次预言差的临床的回答到类固醇治疗。 | Tryggve Ljung Sofie Lundberg Mark Varsanyi Catharina Johansson Peter T Schmidt Max Herulf Jon O Lundberg Per M Hellstr(o|¨)m | 2006 | World Journal of Gastroenterology2006，12，21： | 10 |
| 12 | 全国青少年的卷烟需求及影响因素显示文摘 | 毛正中 杨功焕 马继民 Jon Samet Marion Ceraso | 2002 | 中国公共卫生2002，18，8： | 9 |
| 13 | A reconnaissance of Cu isotopic compositions of hydrothermal vein-type copper deposit, Jinman, Yunnan, China显示文摘The Jinman deposit is a low-temperature hydrothermal vein-type copper deposit, which occurs along faults and fractures within Middle Jurassic sandstone and mudstone units of the Lanping-Simao Mesozoic-Cenozoic basin of Yunnan Province. In this note, we report for the first time the Cu isotopic compositions of Cu-sulfides from the Jinman deposit. The data show large variations and low δ65Cu values of -3.70‰ to +0.30‰, which are in sharp con-trast to the δ65Cu values of high-temperature mag-matic-hydrothermal copper deposits (-0.62‰ to +0.40‰) and the modern ocean-floor massive sulfide deposits (-0.48‰ to +1.15‰). It is suggested that the Cu isotope fractionation at Jinman is affected mainly by the following factors, i.e. a low temperature of ore formation (150-286℃); a sedimen-tary source for ore materials; various stages of ore deposition; and involvement of organic matter in the ore-forming proc-esses. | JIANG Shaoyong Jon Woodhead YU Jimin PAN Jiayong LIAO Oiling WU Nanping | 2002 | Chinese Science Bulletin2002，47，3： | 9 |
| 14 | 视网膜微血管异常的5年发病率及其与高血压的相关性显示文摘目的描述“北京眼病研究”人群从2001年至2006年5年随访问非糖尿病老年人中视网膜微血管异常的累积发病率,并分析其与高血压的相关性。设计人群为基础的队列研究。研究对象“北京眼病研究”基线人群中参加2006年随访调查者3251人。方法对每位受检者在基线调查和随访调查时均进行了问卷调查和全面的眼科检查,其中包括散瞳后彩色眼底照相。每位受检者随机选一眼进行眼底照片中视网膜血管异常的评价。评价指标包括局限性视网膜动脉缩窄(FN)、动静脉交叉压迫征(AVN)和视网膜病变,评价采用半定量的方法进行。问卷调查以了解一般情况、眼部及全身疾病史、治疗史和吸烟饮酒史。随访调查时进行了身高、体重和血压测量,并收集空腹血液标本检测血糖、血脂。考虑的危险因素包括:年龄、性别、城乡、人均收入、教育程度、高血压、高血脂、冠心病病史、脑卒中病史、糖尿病、体重指数(BMI)、吸烟饮酒、眼局部可能相关疾病(青光眼、老年性黄斑变性和中央份支视网膜静脉阻塞等)和屈光状态等。通过对比基线和5年随访时受检者视网膜微血管的变化,确定视网膜微血管异常的5年发病率和改变情况(进展或消退)。根据治疗情况,将高血压患者分为血压控制的治疗组、未控制的治疗组和未治疗组。比较血压正常者与高血压病患者、不同高血压治疗情况组问视网膜微血管异常的发病率、进展率和好转率的差异。主要指标视网膜微血管异常的发病率、进展率和好转率。结果排除患有糖尿病或任何视网膜视神经疾病等眼局部病变的患者后,2058例受检者纳入本研究,其中女性1409例(68.5%)。平均年龄(53.8+9.5)岁。FN、AVN和视网膜病变的5年累积发病率分别为4.1%,1.4%和3.3%。高血压患者中FN、AVN和视网膜病变的5年发病率明显高于血压正常者(P均〈0.01)。对年龄、性别和居住地区进行调整后,平均动脉压每增加10mmHg,FN、AVN和视网膜病变的5年发病率分别增加1.58倍(95%CI:1.24—2.00;P〈0.001),1.55倍(95%CI:1.04。2.32;P=O.03),1.46倍(95%CI:1.12~1.91;P=0.005)。对年龄、性别和居住地区进行调整后,高血压分级每增加1级,FN好转率减少28%。相应的,血压控制组的FN的好转率(44.4%)明显高于未控制组(22.6%)和未治疗组(11.5%)(P=-O.01)。结论在非糖尿病患者中,高血压与视网膜微血管异常的发病率和进展变化具有强相关性。血压控制理想者的视网膜微血管异常发病率较低,局限性动脉缩窄消退率较高。这表明如果高血压控制良好,作为视网膜微血管异常的早期表现,局限性视网膜动脉缩窄是可逆的。 | 王爽 徐亮 Jons Jost B 王亚星 游启生 王云松 杨桦 周金琼 刘雪 | 2013 | 眼科2013，22，6： | 9 |
| 15 | 苏雪林论鲁迅之“谜”显示文摘一“以其人之道,还治其人之身。”
苏雪林教授(1897—1999),曾在1930年代初被阿英(钱杏邮,1900—1977)称为“女性作家中最优秀的散文作者”。1966年11月,年近70岁的苏雪林在其名为《我论鲁迅》(该书收集旧文十余篇,《自序》作于台湾台南)一书的开篇《自序》中明确写道:“反鲁,几乎成了我半生的事业。” | 寇志明(Jon Eugenevon Kowallis) | 2011 | 鲁迅研究月刊2011，，4： | 8 |
| 16 | Phytochrome-lnteracting Factors (PIFs) as Bridges between Environmental Signals and the Circadian Clock: Diurnal Regulation of Growth and Development显示文摘The rotation of the Earth around its axis results in distinct changes in light and temperature during a 24-h day/night cycle.Plants being sessile are constantly and predictably exposed to these environmental changes.It is therefore critical for them to properly perceive environmental signals in order to effectively manage growth and development. | Jieun Shin Muhammad Usman Anwer Seth Jon Davis | 2013 | Molecular Plant2013，6，3： | 8 |
| 17 | Transfer of Heavy Metals from Soils to Vegetables and Associated Human Health Risks at Selected Sites in Pakistan显示文摘Contamination of the food chain with heavy metals is considered as one of the major environmental pathways of human exposure to metals leading to potential health risks. This study aimed to investigate the concentrations of heavy metals such as copper(Cu),zinc(Zn), chromium(Cr), nickel(Ni), and manganese(Mn) in agricultural soils and food crops(fruit, leaf, and root vegetables), and their associated health risks to the local population in selected southern districts of Khyber Pakhtunkhwa Province, Pakistan. The concentrations of the selected metals in soil varied over a wide range, in the following decreasing order: Mn > Zn > Cr > Ni > Cu.The bioaccumulation of metals in vegetables was within the permissible risk limits, except for Cr which showed higher contamination in all the tested food crops. The trend of metal transfer factors for different vegetables was in the order of Cu > Ni > Cr > Mn >Zn, while the calculated daily intake of metals(DIM) in adults and children through consumption of food crops was in the decreasing order of Mn > Zn > Ni > Cr > Cu. The health risk index(HRI) values for the heavy metals for both adults and children were less than 1. Therefore, no significant health risk is anticipated for the local consumers through ingestion of these food crops. | Zahir Ur REHMAN Sardar KHAN Mohammad Tahir SHAH Mark L.BRUSSEAU Said Akbar KHAN Jon MAINHAGU | 2018 | Pedosphere2018，28，4： | 7 |
| 18 | Clinical and economic consequences of pancreatic fistula after elective pancreatic resection显示文摘BACKGROUND:Postoperative pancreatic fistula is the main cause of morbidity after pancreatic resection.This study aimed to quantify the clinical and economic consequences of pancreatic fistula in a medium-volume pancreatic surgery center.METHODS:Hospital records from patients who had undergone elective pancreatic resection in our department were identified.Pancreatic fistula was defined according to the International Study Group on Pancreatic Fistula(ISGPF).The consequences of pancreatic fistula were determined by treatment cost,hospital stay,and out-patient follow-up until the pancreatic fistula was completely healed.All costs of the treatment are calculated in Euros.The cost increase index was calculated for pancreatic fistula of grades A,B,and C as multiples of the total cost for the no fistula group.RESULTS:In 54 months,102 patients underwent elective pancreatic resections.Forty patients(39.2%) developed pancreatic fistula,and 54 patients(52.9%) had one or more complications.The median length of hospital stay for the no fistula,grades A,B,and C fistula groups was 12.5,14,20,and 59 days,respectively.The hospital stay of patients with fistula of grades B and C was significantly longer than that of patients with no fistula(P<0.001).The median total cost of the treatment was 4952,4679,8239,and 30 820 Euros in the no fistula,grades A,B,and C fistula groups,respectively.CONCLUSIONS:The grading recommended by the ISGPF is useful for comparing the clinical severity of fistula and for analyzing the clinical and economic consequences of pancreatic fistula.Pancreatic fistula prolongs the hospital stay and increases the cost of treatment in proportion to the severity of the fistula. | Filip Ceka Bohumil Jon Zdeněk ubrt Alexander Ferko | 2013 | Hepatobiliary & Pancreatic Diseases International2013，12，5： | 7 |
| 19 | 桑沟湾和胶州湾沉积物耗氧率研究显示文摘为评价浅海海域底层在碳元素生物地化循环中的作用,采用现场取样培养法测定了黄海桑沟湾和胶州湾的沉积物耗氧率。桑沟湾5月和8月的沉积物耗氧率分别为15和24 mmol.m-2.d-1;胶州湾8月的沉积物耗氧率为18 mmol.m-2.d-1。回归分析表明,2个湾的沉积物耗氧率分别与沉积物表层的有机碳和总氮含量正相关。取呼吸商为0.8,得到桑沟湾底层对有机碳的矿化率占水层初级生产力的102%(5月)和67%(8月),胶州湾底层对有机碳的矿化率占水层初级生产力的28%(8月)。取桑沟湾颗粒有机碳的生物沉积速率为236 mg.m-2.d-1,得到底层对有机碳的埋置效率为40%(5月)和3%(8月),埋置的有机碳占水层初级生产力的69%(5月)和2%(8月);胶州湾颗粒有机碳的自然沉积速率为251 mg.m-2.d-1,底层对有机碳的埋置效率为32%(8月),埋置的有机碳占水层初级生产力的13%(8月)。 | 张学雷 朱明远 陈尚 GRANT Jon MARTIN Jean-Louis | 2006 | 海洋科学进展2006，24，1： | 7 |
| 20 | Authoritative sources in a hyperlinked environment显示文摘 | Jon M. Kleinberg | 1999 | Journal of the ACM (JACM)1999，，5： | 6 |
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