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| 1 | SARS-CoV-2 infects human neural progenitor cells and brain organoids显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)1 has resulted in over 13 million confirmed cases and more than 580,045 deaths across 218 countries and geographical regions as of July 16,2020.This novel coronavirus primarily causes respiratory illness with clinical manifestations largely resembling those of SARS.However,neurological symptoms including headache,anosmia,ageusia,confusion,seizure,and encephalopathy have also been frequently reported in COVID-19 patients. | Bao-Zhong Zhang Hin Chu Shuo Han Huiping Shuai Jian Deng Ye-fan Hu Hua-rui Gong Andrew Chak-Yiu Lee Zijiao Zou Thomas Yau Wutian Wu Ivan Fan-Ngai Hung Jasper Fuk-Woo Chan Kwok-Yung Yuen Jian-Dong Huang | 2020 | Cell Research2020，30，10： | 8 |
| 2 | 罗布泊南部野双峰驼的分布与环境显示文摘在1995-1996年两年调查的基础上,我们又利用家驼队深入荒漠腹地,考察了罗布泊南部野双峰驼的分布和栖息环境。结果表明在罗布泊南部的湖岸区、阿尔金山北麓及山前丘陵地带均有野驼分布。库姆塔格沙漠中部无野驼进入,但其西侧戈壁及丘间谷地为野驼南北迁徙的通道,冬季野驼主要集中活动在科什兰孜等罗布泊南岸及阿奇克谷地;夏季主要在山区北麓活动,所以应将该区域与上述分布区同归于一个分布区整体,即南北配置的景观复合体结构的分布区。阿尔金山野骆驼保护区内的野驼分布区,实际为该区域野驼分布区的南部分布区。该区域南北部地貌植被特征差异虽大,但均属于干旱荒漠环境。 | 李维东 袁国映 John Hare 袁磊 Jasper Evans | 1998 | 干旱区研究1998，15，1： | 7 |
| 3 | 在有从 Valsalva 的正确湾穴产生的一根单个冠的动脉的一个病人的急性冠的症候群显示文摘 Coronary artery anomalies are usually encountered as coincidental findings during coronary angiography or at autopsy.Life threatening symptoms,such as arrhythmias,syncope,myocardial infarction,or sudden death,can occur in up to 20% of patients.However,the majority of anomalies(80%) are benign and asymptomatic.A single coronary artery(SCA) is one of the most rarely seen coronary anomalies with an incidence of 0.05%.We report the case of a 55-year old male patient who presented with symptoms of chest pain associated with an acute myocardial infarction.Coronary angiography revealed an anomalous left main coronary artery(LMCA) originating from the right coronary ostium,and an occluded distal right coronary artery.The occluded distal right coronary artery was successfully treated by thrombosuction and stenting.In order to confirm the origin and course of the SCA,multi-slice computed tomography(MSCT) of the heart was performed after coronary angiography.MSCT showed that the anomalous LMCA originated from the right coronary artery ostium and then passed the interventricular septum,instead of being intra arterial,and under the right ventricular infundibulum.The anomalous LMCA was classified as R-Ⅱ S subtype according to Lipton’s classification. | Crista Liesting Jasper Jan Brugts Marcellinus Johannes Maria Kofflard Attila Dirkali | 2012 | World Journal of Cardiology2012，4，8： | 7 |
| 4 | Selective laser melting of near-α titanium alloy Ti-6Al-2Zr-1Mo-1V:Parameter optimization, heat treatment and mechanical performance显示文摘This paper presents a comprehensive study conducted to optimize the selective laser melting(SLM)parameters and subsequent heat-treatment temperatures for near-α high-temperature titanium alloy Ti-6 Al-2 Zr-1 Mo-1 V(TA15),which is widely used in the aerospace industry.Based on the surface morphology and relative density analysis,the optimized process parameters were:laser power from 230 W to 380 W,scan speed from 675 mm/s to 800 mm/s,scan spacing of 0.12 mm,and layer thickness of0.03 mm.The effects of the laser power and the layer thickness on the phase constitutions,microstructure features,as well as room-temperature and high-temperature(500℃) tensile properties,were then studied to obtain an in-depth understanding of SLM-built TA15.Six typical temperatures(650,750,850,950,1000 and 1100℃) covering three representative temperature ranges,i.e.,martensite partial decomposition temperature range,martensite complete decomposition temperature range and above βtransus temperature,were subsequently selected as heat-treatment temperatures.The heat treatmentmicrostructure-mechanical property relationships of SLM-built TA15 were elucidated in detail.These results provide valuable information on the development of SLM-built TA15 alloy for industrial applications,and these findings are also beneficial to additive manufacturing of other near-α Ti alloys with desirable high-temperature properties. | Chao Cai Xu Wu Wan Liu Wei Zhu Hui Chen Jasper Chu Dong Qiu Chen-Nan Sun Jie Liu Qingsong Wei Yusheng Shi | 2020 | Journal of Materials Science & Technology2020，54，22： | 7 |
| 5 | 很快进步的心脏的淀粉样变性病的一个不正常的演讲的 Echocardiographic 特征显示文摘 We present the case of a 66 year old male who presented with dyspnea and reduced exercise tolerance. Echocardiography demonstrated impaired left ventricular (LV) function and restrictive diastolic function with pronounced concentric left ventricular hypertrophy (LVH) without a history of hypertension and no aortic valve stenosis. Differential diagnostics of concentric LVH are discussed in detail. In the current case, cardiac amyloidosis (AL) amyloidosis was diagnosed and confirmed by serum amyloid P (SAP) scintigraphy and abdominal fat aspiration biopsy. This case shows the rapid decline in clinical condition with progression of cardiac involvement of AL. As discussed in detail, cardiac involvement in AL-amyloidosis generally denotes a poor prognosis, regardless of the method of treatment. | Jasper J Brugts Jaco Houtgraaf Bouke PC Hazenberg Marcel JM Kofflard | 2013 | World Journal of Cardiology2013，5，5： | 6 |
| 6 | A pan-sarbecovirus vaccine induces highly potent and durable neutralizing antibody responses in non-human primates against SARS-CoV-2 Omicron variant显示文摘Dear Editor,Since the outbreak of Coronavirus Disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,numerous SARS-CoV-2 variants of concern(VOCs),such as Alpha(B.1.1.7),Beta(B.1.351),Gamma(P.1),and Delta(B.1.617.2),have emerged.Recently,the newly identified SARS-CoV-2 VOC,Omicron(B.1.1.529),has rapidly spread in many countries1 and is expected to replace Delta as the dominant variant circulating in the world.Compared to other VOCs,Omicron contains at least 32 mutations in spike(S)protein,including 15 mutations in the receptor-binding domain(RBD),and these mutations are known to confer resistance to neutralizing antibodies(nAbs)and sera of convalescent patients and people who have received COVID-19 vaccines.2–5 Therefore,vaccines able to induce potent and durable neutralizing antibodies against Omicron and other VOCs are urgently needed. | Zezhong Liu Jasper Fuk-Woo Chan Jie Zhou Meiyu Wang Qian Wang Guangxu Zhang Wei Xu Kenn Ka-Heng Chik Yilong Zhang Youchun Wang Kwok-Yung Yuen Lu Lu Shibo Jiang | 2022 | Cell Research2022，32，5： | 4 |
| 7 | Composite tissue allotransplantation: opportunities and challenges显示文摘Vascularized composite allotransplants(VCAs)have unique properties because of diverse tissue components transplanted en mass as a single unit.In addition to surgery,this type of transplant also faces enormous immunological challenges that demand a detailed analysis of all aspects of alloimmune responses,organ preservation,and injury,as well as the immunogenicity of various tissues within the VCA grafts to further improve graft and patient outcomes.Moreover,the side effects of long-term immunosuppression for VCA patients need to be carefully balanced with the potential benefit of a non-life-saving procedure.In this review article,we provide a comprehensive update on limb and face transplantation,with a specific emphasis on the alloimmune responses to VCA,established and novel immunosuppressive treatments,and patient outcomes. | Jasper Iske Yeqi Nian Ryoichi Maenosono Max Maurer Igor M.Sauer Stefan G.Tullius | 2019 | Cellular & Molecular Immunology2019，16，4： | 4 |
| 8 | Light field on a chip: metasurface-based multicolor holograms显示文摘Multicolor holography can faithfully record the color,depth,parallax,and other properties of scenes and have thus found numerous applications,for example,in optical document security,nonvolatile data storage,and virtual or augmented reality systems.Nanophotonic metasurfaces present multiple degrees of freedom to manipulate the properties of optical fields at visible wavelengths.These in turn provide opportunities for metasurface-based multicolor holography.We describe recent developments in multicolor metasurface holograms.These are categorized based on their color-separating mechanisms rather than their structural properties,such as whether they are plasmonic or dielectric.We hope this review will provide readers with new insights and thus help extend applications of metasurface-based multicolor holography to other fields. | Dandan Wen Jasper J.Cadusch Jiajun Meng Kenneth B.Crozier | 2021 | Advanced Photonics2021，3，2： | 3 |
| 9 | The Latent Structure of Medically Unexplained Symptoms and Its Relation to Functional Somatic Syndromes显示文摘 | Michael Witth?ft Wolfgang Hiller Noelle Loch Fabian Jasper | 2013 | International Journal of Behavioral Medicine2013，，2： | 2 |
| 10 | Ability of the Gaussian plume model to predict and describe spore dispersal over a potato crop显示文摘 | H.P. Spijkerboer J.E. Beniers D. Jaspers H.J. Schouten J. Goudriaan R. Rabbinge W. van der Werf | 2002 | Ecological Modelling2002，，1： | 2 |
| 11 | Blood lactate monitoring in critically ill patients: A systematic health technology assessment显示文摘 | Tim C. Jansen Jasper van Bommel Jan Bakker | 2009 | Critical Care Medicine2009，，10： | 2 |
| 12 | A large scale distributed intrusion detection framework based on attack strategy analysis显示文摘 | Huang M Jasper R Wicks T | 1999 | Computer Networks1999，31，3： | 2 |
| 13 | 查看详情显示文摘 | Jasper W J Gamier S J Potlap lli H | | 0，，： | 2 |
| 14 | Controlling the gelation temperature of biomimetic polyisocyanides显示文摘Thermosensitive polymers show an entropy-driven transition from a well-solvated to a poorly solvated polymer chain, resulting in a more compact globular conformation. The transition at the lower critical solution temperature(LCST) is often sharp, which allows for a wide range of smart material applications.At the LCST, oligo(ethylene glycol)-substituted polyisocyanides(PICs) form soft hydrogels, composed of polymer bundles similar to biological gels, such as actin, fibrin and intermediate filaments. Here, we show that the LCST of PICs strongly depends linearly on the length of the ethylene glycol(EG) tails; every EG group increases the LCSTand thus the gelation temperature by nearly 30 ℃. Using a copolymerisation approach, we demonstrate that we can precisely tailor the gelation temperature between 10 ℃ and 60 ℃and, consequently, tune the mechanical properties of the PIC gels. | Paul H.J. Kouwer Paula de Almeida Onno ven den Boomen Zaskia H. Eksteen-Akeroyd Roel Hammink Maarten Jaspers Stijn Kragt Mathijs F.J. Mabesoone RoelandJ.M. Nolte Alan E. Rowan Martin G.T.A. Rutten Vincent A.A. Le Sage Daniel C. Schoenmakers Chengfen Xing Jialiang xu | 2018 | Chinese Chemical Letters2018，29，2： | 2 |
| 15 | Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant显示文摘Dear Editor,Most recently,a new SARS-CoV-2 variant of concern(VOC)Z Omicron(B.1.1.529),was first reported to the World Health Organization(WHO)from South Africa and then quickly spread to many countries,1,2 posing a serious threat to current vaccine prevention and antibody therapeutic strategies.Several studies have reported that the Omicron variant successfully escapes from neutralizing antibodies elicited by COVID-19 vaccines or from COVID-19 convalescent patients. | Shuai Xia Jasper Fuk-Woo Chan Lijue Wang Fanke Jiao Kenn Ka-Heng Chik Hin Chu Qiaoshuai Lan Wei Xu Qian Wang Chao Wang Kwok-Yu ng Yuen Lu Lu Shibo Jiang | 2022 | Cell Research2022，32，4： | 2 |
| 16 | Repeated occurrence of palaeo-wildfires during deposition of the Bahariya Formation(early Cenomanian) of Egypt显示文摘The Upper Cretaceous(early Cenomanian)Bahariya Formation of Egypt has an outstanding reputation for its wealth of vertebrate remains,including a variety of iconic dinosaurs,like the carnivorous Spinosaurus and Carcharodontosaurus,as well as the herbivorous Aegyptosaurus and Paralititan.Besides these dinosaur fossils,the Bahariya Formation yielded also a wealth of invertebrate and plant remains,but even today many aspects concerning the continental palaeoenvironments reflected in these deposits(including the occurrence of palaeo-wildfires)have not been studied in detail.So far six distinct macro-charcoal bearing levels could be identified within the type section of the Bahariya Formation at Gabal El Dist profile,one of the most prolific outcrops of this formation in terms of fossil occurrence located in the north of the Bahariya Oasis,Western Desert,Egypt.Most of the charcoal investigated by means of SEM originates from ferns,pointing to a considerable proportion of this plant group within the palaeo-ecosystems that experienced fires.Gymnosperms and(putative)angiosperms have less frequently been identified.The collected data present evidence that the landscapes at the northern shores of Gondwana repeatedly experienced palaeo-wildfires,adding extra proof to previous statements that the Late Cretaceous was a fiery world on a global scale. | Haytham El Atfy Tarek Anan Andre Jasper Dieter Uhl | 2019 | Journal of Palaeogeography2019，8，4： | 2 |
| 17 | Extensive contact tracing and screening to control the spread of vancomycin-resistant Enterococcus faecium ST414 in Hong Kong显示文摘 | CHENG Vincent Chi-chung TAI Josepha Wai-ming NG Modissa Lai-ming CHAN Jasper Fuk-woo WONG Sally Cheuk-ying LI Iris Wai-sum CHUNG Hon-ping LO Wai-kei YUEN Kwok-yung HO Pak-leung | 2012 | Chinese Medical Journal2012，，19： | 2 |
| 18 | c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches 显示文摘 | Hallaert DY Jaspers A van Noesel C J | 2008 | Blood2008，112，13： | 1 |
| 19 | Use of nuclepore filters for counting bacteria by fluorescence microscopy 显示文摘 | Hobbie J E Daley R J Jasper S | 1977 | Applied and Environmental Microbiology1977，33，： | 1 |
| 20 | Experimental Investigation of Runawayelectron Generation in Textor显示文摘 | Jaspers R Finken K H Mank G | 1993 | Nucl Fusion1993，，12： | 1 |
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