|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Adalimumab sustains clinical remission and overall clinical benefit after 2?years of therapy for Crohn’s disease显示文摘 | R.PANACCIONE J.‐F.COLOMBEL W. J.SANDBORN P.RUTGEERTS G. R.D’HAENS A. M.ROBINSON J.CHAO P. M.MULANI P. F.POLLACK | 2010 | Alimentary Pharmacology & Therapeutics2010，，12： | 1 |
| 2 | The CHOICE trial: adalimumab demonstrates safety, fistula healing, improved quality of life and increased work productivity in patients with Crohn’s disease who failed prior infliximab therapy显示文摘 | S.Lichtiger D. G.Binion D. C.Wolf D. H.Present A. G.Bensimon E.Wu A. P.Yu A. T.Cardoso J.Chao P. M.Mulani K. G.Lomax J. D.Kent | 2010 | Alimentary Pharmacology & Therapeutics2010，，10： | 1 |
| 3 | The enhanced negative thermal expansion in less-oxygen-vacancies copper pyrophosphate显示文摘For oxides,controlling the concentration of oxygen vacancy is a useful way to optimize their functional properties.However,when it comes to the field of negative thermal expansion(NTE),much less attention has been paid to the effect of oxygen vacancy on NTE,though oxide-typed NTE materials account for more than 40%of the total NTE materials.Here,we report that the linear coefficient of thermal expansion at 250–350 K of copper pyrophosphate(i.e.,Cu_(2)P_(2)O_(7))can be significantly improved from–13.88 to–36.60 ppm/K when the synthesis temperature is raised from 1073 to 1373 K.The combined study including X-ray absorption near edge structure,neutron powder diffraction,and X-ray diffraction has confirmed the selective vacancies in the O1 site for low-temperature synthesized samples,which suppress both the phase-transition and framework-structure driven NTE simultaneously.Our result proposes a new approach for optimizing the NTE effect of oxides. | L.Lu Xie T.Fei Shi J.Chao Lin X.Kai Zhang X.Kang Zhong K.Ke Liu B.Ke Dong Cheng Yang X.Lian Wang T.Jiao Xiong W.Sheng Yan J.Ping Xu H.Can Chen Wen Yin Ming Li Peng Tong W.Hai Song Y.Ping Sun | 2023 | Journal of Materials Science & Technology2023，，15： | 1 |
| 4 | Effects of dietary energy density on plasma glucose and lipid profile,morphological aspects and chemical characteristics of adipose tissue in finishing pigs显示文摘Peroxisome proliferator-activated receptor-γ (PPAR-γ) plays a pivotal role in controlling adipogenesis.We hypothesized that changes in dietary energy density might alter fat deposition in finishing pigs via modulation of the expression of PPAR-γ.To test this hypothesis,thirty female finishing pigs were fed diets containing low (LD),medium (MD) or high (HD) energy density.Blood samples were collected on day 53,and then the pigs were sacrificed to collect samples of the dorsal subcutaneous (ST),abdominal (AT) and mesenteric (MT) adipose tissue.Compared with pigs fed the MD diet,malate dehydrogenase activity was increased in the ST and MT of pigs fed the HD diet,while activity was decreased in the MT of pigs fed the LD diet (P<0.05).Glucose-6-phosphate dehydrogenase activity was increased in all three fat depots of pigs fed the HD diet (P<0.05) in comparison with pigs fed the MD diet.Both HD and LD diets increased the size of the adipocytes in the AT and MT (P<0.05).Pigs fed the HD diet had a higher cell proliferation index in the ST compared with pigs fed the other two diets (P<0.05).Compared with pigs fed the MD diet,a decreased apoptosis index was seen in the ST of pigs fed the HD diet,and in the AT of pigs fed the LD diet,as well as in the MT of both HD and LD fed pigs (P<0.05).PPAR-γ positive percentage was elevated in the ST and MT of HD fed pigs compared with pigs fed the MD and LD diets,while it was decreased in the ST of LD compared with MD fed pigs (P<0.05).These results suggest that dietary energy density may regulate fat deposition in finishing pigs.It is possible that feeding a high energy diet may induce fat deposition via up-regulation of PPAR-γ expression. | J.Chao Y.L.Liu Y.L.Yin Y.Q.Hou H.L.Zhu X.FKong | 2010 | Journal of Animal Science and Biotechnology2010，1，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员