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| 1 | Pyrrolidine dithiocarbamate reduces ischemia-reperfusion injury of the small intestine显示文摘AIM: To evaluate whether pyrrolidine dithiocarbamate (PDTC), an enhancer of HO production, attenuates intestinal IR injury.METHODS: Eighteen male rats were randomly allocated into three groups: (a) sham; (b) IR, consisting of 30 min of intestinal ischemia, followed by 2-h period of reperfusion; and (c) PDTC treatment before IR. Intestinal microvascular perfusion (IMP) was monitored continuously by laser Doppler fiowmetry. At the end of the reperfusion, serum samples for lactate dehydrogenase (LDH) levels and biopsies of ileum were obtained. HO activity in the ileum was assessed at the end of the reperfusion period.RESULTS: At the end of the reperfusion in the IR group,IMP recovered partially to 42.5% of baseline (P<0.05vs sham), whereas PDTC improved IMP to 67.3% of baseline (P<0.01 vs IR). There was a twofold increase in HO activity in PDTC group (2 062.66±106.11) as compared to IR (842.3±85.12) (P<0.001). LDH was significantly reduced (P<0.001) in PDTC group (585.6±102.4)as compared to IR group (1 973.8±306.5). Histological examination showed that the ileal mucosa was significantly less injured in PDTC group as compared with IR group.CONCLUSION: Our study demonstrates that PDTC improves the IMP and attenuates IR injury of the intestine possibly via HO production. Additional studies are warranted to evaluate the clinical efficacy of PDTC in the prevention of IR injury of the small intestine. | Ismail H Mallick Wen-Xuan Yang Marc C Winslet Alexander M Seifalian | 2005 | World Journal of Gastroenterology2005，11，46： | 8 |
| 2 | GC-ECD and GC-MS Analysis of Profenofos Residues and Its Biochemical Effect in Tomatoes Products显示文摘 | ISMAIL S M M ALI H M HABIBA R A | 1993 | Journal of Agricultural of Food Chemistry1993，41，4： | 1 |
| 3 | The effect of chitosan load- ing on the curing characteristics, mechanical and morphologi- cal properties of chitosan-filled natural rubber(NR) , epoxi- dised natural rubber (ENR) and styrene-butadiene rubber (SBR) compounds 显示文摘 | Ismail H Shaari S M Othman N | 2011 | Polymer Testing2011，30，7： | 1 |
| 4 | Renal replacement therapies in the elderly part in renal transplantation显示文摘 | ISMAIL N HAKIM R M HELDERMAN J H | 1994 | Am J Kidney Dis1994，23，： | 1 |
| 5 | DeterminaTion of flavonoid and phenolic acid contents of clover,cotton and citrus floral honeys显示文摘 | HAMDY A A ISMAIL H M aI-AHWAL A E A | 2009 | J Egypt Public Health Assoc2009，84，34： | 1 |
| 6 | Polyethersulfone(PES)-silver composite UF membrane:effect of silver loading andPVP molecular weight on membrane morphology andantibacterial activity显示文摘 | Basri H Ismail A F Aziz M | 2011 | Desalination2011，273，： | 1 |
| 7 | On the use of Pad'e approximation for performanceevaluation of maximal ratio combining diversity over Weibull fading channels 显示文摘 | Ismail M H Matalgah M M | 2006 | EURASIP Journal on Wireless Commun and Networking2006，2005，： | 1 |
| 8 | Sample preparation technique for artificially cemented soils显示文摘 | ISMAIL M A JOER H A RANDOLPH M F | 2000 | Geotechnieal Testing Journal2000，23，2： | 1 |
| 9 | Oil palm wood flour filled natural rubber composites: The effects of various bonding agents显示文摘 | Ismail H Jaffri R M Rozman H D | 2001 | International Journal of Polymeric Materials2001，49，： | 1 |
| 10 | Effects of role conflict on selected physiological, affective, and performance variables: a laboratory simulation 显示文摘 | Manning M R Ismail A H Sherwood J | 1981 | Multivariate Behavioral Research1981，16，1： | 1 |
| 11 | Efficiency of plant growth-promoting rhizobacteria(PGPR) for the en- hancement of rice growth显示文摘 | Ashrafuzzaman M Farid A H Razi Ismail M | 2009 | African Journal of Biotechnology2009，8，7： | 1 |
| 12 | 源自天然席夫碱的过渡金属配合物在分光光度法测天然水中的Fe(Ⅲ)的应用(英文)显示文摘描述了一种新颖、简便的合成含五齿配位基的大环席夫碱配体的方法,制备和表征了该席夫碱的1∶1包合物。用化学和光谱学方法测定了标题配合物的组成,认为在所有配合物中配位金属原子取八面体结构。数据表明:配体起O2N4六齿结构而每个环绕金属原子在八面体环境中。配合物的红外和1H NMR光谱符合中心金属原子的配位结果。用分光光度法测定了配合物的稳定常数。用共轭余量法(CR method)计算了在热分解的不同阶段配合物活化的动力学和热力学参数。此外,用抑菌圈直径法筛选了配体及其金属配合物抑制细菌和真菌的能力。用回收率试验研究了天然螯合配体在不同天然水体中对Fe(Ⅲ)离子配合作用的影响。 | Khalil M M H Mohamed G G Ismail E H Zayed M E Kamel B A | 2012 | 无机化学学报2012，28，7： | 1 |
| 13 | Use of sewage sludge ash in asphaltic paving mixes inhot regions 显示文摘 | MOHAMMED H A S ISMAIL M M RAHMAN A M B | 1995 | Construction and Building Materials1995，9，1： | 1 |
| 14 | Kinetics and polymerization characteristics for some polyvinyl acetate emulsions prepared by different redox pair initiation systems显示文摘 | SHAFFEI K A AYOUB M M H ISMAIL M N | 1998 | European Polymer Journal1998，34，34： | 1 |
| 15 | Morpho-tectonic analysis of the Tekeze River and the Blue Nile drainage systems on the Northwestern Plateau, Ethiopia显示文摘 | ISMAIL E H ABDELSALAM M G | 2012 | Journal of African earth sciences2012，69，： | 1 |
| 16 | Recovery of pure Mn SO4·H2O by reductive leaching of manganese from pyrolusite ore by sulfuric acid and hydrogen peroxide显示文摘 | Nayl A A Ismail I M Aly H F | 2011 | International Journal of Mineral Processing2011，，100： | 1 |
| 17 | EPDM/modified halloysite nanomposite 显示文摘 | Pooria P H Ismail M N Ahmad F | 2010 | Applied Clay Science2010，48，： | 1 |
| 18 | Expression of NFkB in prostate cancer lymph node metastases 显示文摘 | Ismail H A Lessard L Mes-Masson A M | 2004 | Prostate2004，58，3： | 1 |
| 19 | The effects of filler loading and vulcanisation system on properties of oil palm wood flournatural rubber composites显示文摘 | Ismail H Jaffri R M Rozman H D | 2003 | Journal of Elastomers and Plastics2003，35，2： | 1 |
| 20 | Role of cy- tochrome P450s in insecticide resistanceimpact on the con-trol of mosquito-borne diseases and use of insecticides on Earth显示文摘 | David J P Ismail H M Chandor-Proust A | 2013 | Philosophical Transactions of the Royal Society of London Series B Biological Sciences2013，368，： | 1 |
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