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| 1 | Artificial Intelligence in Steam Cracking Modeling: A Deep Learning Algorithm for Detailed Effluent Prediction显示文摘Chemical processes can bene t tremendously from fast and accurate ef uent composition prediction for plant design, control, and optimization. The Industry 4.0 revolution claims that by introducing machine learning into these elds, substantial economic and environmental gains can be achieved. The bottleneck for high-frequency optimization and process control is often the time necessary to perform the required detailed analyses of, for example, feed and product. To resolve these issues, a framework of four deep learning arti cial neural networks (DL ANNs) has been developed for the largest chemicals production process steam cracking. The proposed methodology allows both a detailed characterization of a naphtha feedstock and a detailed composition of the steam cracker ef uent to be determined, based on a limited number of commercial naphtha indices and rapidly accessible process characteristics. The detailed char- acterization of a naphtha is predicted from three points on the boiling curve and paraf ns, iso-paraf ns, ole ns, naphthenes, and aronatics (PIONA) characterization. If unavailable, the boiling points are also estimated. Even with estimated boiling points, the developed DL ANN outperforms several established methods such as maximization of Shannon entropy and traditional ANNs. For feedstock reconstruction, a mean absolute error (MAE) of 0.3 wt% is achieved on the test set, while the MAE of the ef uent predic- tion is 0.1 wt%. When combining all networks using the output of the previous as input to the next the ef uent MAE increases to 0.19 wt%. In addition to the high accuracy of the networks, a major bene t is the negligible computational cost required to obtain the predictions. On a standard Intel i7 processor, predictions are made in the order of milliseconds. Commercial software such as COILSIM1D performs slightly better in terms of accuracy, but the required central processing unit time per reaction is in the order of seconds. This tremendous speed-up and minimal accuracy loss make the presented framework highly suitable for the continuous monitoring of dif cult-to-access process parameters and for the envi- sioned, high-frequency real-time optimization (RTO) strategy or process control. Nevertheless, the lack of a fundamental basis implies that fundamental understanding is almost completely lost, which is not always well-accepted by the engineering community. In addition, the performance of the developed net- works drops signi cantly for naphthas that are highly dissimilar to those in the training set. | Pieter PPlehiers Steffen HSymoens Ismaël Amghizar Guy B.Marin Christian V.Stevens Kevin M.Van Geem | 2019 | Engineering2019，5，6： | 9 |
| 2 | intrahepatic cholangiocarcinoma 的胰腺的复发: 案例报告和文学的评论显示文摘 Intrahepatic cholangiocarcinomas(ICC)are malignant tumors arising from the intrahepatic bile ducts that frequently recur after resection.The main sites of recurrence are the remnant liver,lymph nodes and lungs.Metastasis to the pancreas has never been reported.This case describes a 24-year-old woman who underwent a hepatic lobectomy in 2008 for an ICC.Almost 4years after her surgery she presented with a pancreatic mass and lung nodules.An endoscopic ultrasound guided fine needle aspiration of the pancreatic mass and a video-assisted thoracoscopic surgery resection for the lung nodules were performed for diagnostic purposes.Pathological analyses of specimens revealed recurrence of her primary ICC in both pancreas and lungs.Subsequently,the patient received systemic chemotherapy.The patient is currently off chemotherapy and remains well.Moreover,she is pregnant.This is the first report of an ICC with pancreatic metastasis. | Isma?l Labgaa Gonzalo Carrasco-Avino Maria Isabel Fiel Myron Eliot Schwartz | 2014 | World Journal of Gastrointestinal Surgery2014，6，4： | 2 |
| 3 | Thalassemia inter- media: Revisited显示文摘 | Taher A Isma'eel H Cappellinin MD | 2006 | Blood Cells Mol Dis2006，37，1： | 1 |
| 4 | Thalassemia intermedia:revisited显示文摘 | Taher A Isma'eel H Cappellini MD | 2006 | Blood Cells Mol Dis2006，37，： | 1 |
| 5 | Prospective analysis of risk factors and distribution of venous thromboembolism in the population-based Malmo Thrombophilia Study (MATS)显示文摘 | Isma N Svensson PJ Gottsater A | 2009 | Thromb Res2009，124，： | 1 |
| 6 | Rehabilitation of El Yahoudia dumping site, Tunisia显示文摘 | M. Za?¨ri M. Ferchichi A. Isma?¨l M. Jenayeh H. Hammami | 2004 | Waste Management2004，，10： | 1 |
| 7 | Prevalence of Throm-boembolic Events among 8,860 Patients with ThalassemiaMajor and Intermedia in the Mediterranean Area and Iran显示文摘 | Taher A Isma eel H Mehio G | 2006 | Thromb Haemost2006，96，4： | 1 |
| 8 | Does supervised exercise after deep venous thrombosis improve recanalization of occluded vein segments? A randomized study显示文摘 | Isma N Johanssson E Bjork A | 2007 | J Thromb Thrombolysis2007，23，1： | 1 |
| 9 | Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran显示文摘 | Taher A Isma'eel H Mehio G | 2006 | Thrombosis and Haemostasis2006，96，4： | 1 |
| 10 | Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran显示文摘 | Taher A Isma'eel H Mehio G | 2006 | Thromb Haemost2006，96，4： | 1 |
| 11 | Does supervisedexere is eafler deep venous thrombosis improve recanalization of occluded vein seg- ments? A randomized study 显示文摘 | Isma N Johanssson E Bjork A | 2007 | J Thromb Thrnmbolysis2007，71，23： | 1 |
| 12 | Thalassemia inter-media: Revisited显示文摘 | Taher A Isma'eel H Cappellini MD | 2006 | Blood Cells Mol Dis2006，37，： | 1 |
| 13 | Advances in telemedicine for the management of the elderly cardiac patient显示文摘Telemedicine is the use of information and communication technology to deliver healthcare at a distance.It has been resorted to during the COVID-19 pandemic to lessen the need for in-person patient care decreasing the risk of transmission,and it can be of benefit afterward in the management of cardiac disease.The elderly population has unique challenges concerning the use of telehealth technologies.We thus review the advances in telemedicine technologies in treating elderly cardiac patients including in our discussion only studies with a mean age of participants above 60.Remote monitoring of blood pressure,weight,and symptoms,along with home ECG recording has been found to be superior to usual in-clinic follow up.Combining remote monitoring with video conferencing with physicians,patient education websites,and applications is also of benefit.Remote monitoring of Implantable Cardioverter Defibrillators(ICD)and Cardiac Resynchronization Therapy Defibrillators(CRT-D)is also beneficial but can be at the cost of an increase in both appropriate and inappropriate interventions.Implantable sensing devices compatible with remote monitoring have been developed and have been shown to improve care and cost-effectiveness.New smartphone software can detect arrhythmias using home ECG recordings and can detect atrial fibrillation using smartphone cameras.Remote monitoring of implanted pacemakers has shown non-inferiority to in clinic follow up.On the other hand,small-scale questionnaire-based studies demonstrated the willingness of the elderly cardiac patients to use such technologies,and their satisfaction with their use and ease of use.Large-scale studies should further investigate useability in samples more representative of the general elderly population with more diverse socioeconomic and educational backgrounds.Accordingly,it seems that studying integrating multiple technologies into telehealth programs is of great value.Further efforts should also be put in validating the technologies for specific diseases along with the legal and reimbursement aspects of the use of telehealth. | Nadim El Jamal Bernard Abi-Saleh Hussain Isma’eel | 2021 | Journal of Geriatric Cardiology2021，18，9： | 1 |
| 14 | Ziprasidone and haloperidol in the treatment of acute exacerbation of schizophrenia and schizoaffective discorder:comparison of intramuscular and oral formulations in a 6-week,randomized,blinded-assessment study显示文摘 | Shlomo Brook Jeorg Walden Isma Benattia Cynthia O.Siu Steven J.Romano | | 0，，04： | 1 |
| 15 | Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran显示文摘 | Taher A Isma’eel H Mehio G | 2006 | Thromb Haemost2006，96，4： | 1 |
| 16 | Antioxidant activity of benzoxazolinonic and benzothiazolinonic derivatives in the LDL oxidation model显示文摘 | Isma?l Yekini Fatma Hammoudi Fran?oise Martin-Nizard Sa?d Yous Nicolas Lebegue Pascal Berthelot Pascal Carato | 2009 | Bioorganic & Medicinal Chemistry2009，，22： | 1 |
| 17 | Thalassemia intermedia: Revisited显示文摘 | Ali Taher Hussain Isma’eel Maria D. Cappellini | 2006 | Blood Cells, Molecules and Diseases2006，，1： | 1 |
| 18 | The diagnostic ac- curacy of 64-detector cardiac computed tomography compared with stress nuclear imaging in patients undergoing invasive cardi- ac catheterization显示文摘 | Hamirani Y S Isma'eel H Larijani V | 2010 | J Comput Assist Tomogr2010，34，5： | 1 |
| 19 | The effect of carbon black particle size on multifunction additive-carbon black interaction显示文摘 | H Isma P K Frea E Shen | 1995 | Eur Polym J1995，31，11： | 1 |
| 20 | The effect of multifunctional additive in white rice husk ash filled natural rubber compounds显示文摘 | H Isma M N Nasa H D Rozm | 1999 | Eur Polym J1999，35，： | 1 |
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