| 1 | Antioxidant and antiglycation properties of two mango(Mangifera indica L.) cultivars from Senegal显示文摘Objective: To evaluate the total phenolic contents, antioxidant and antiglycation activities of leaves, barks, roots and kernels from two cultivars of Mangifera indica(Anacardiaceae). Methods: Total phenolic contents were determined by using Folin-Ciocalteu's method. The antioxidant activities were assessed by three different protocols including DPPH, oxygen radical absorbance capacity and iron(Ⅱ) chelation assays. In addition, in vitro bovine serum albumin/D-ribose assay was chosen to evaluate the antiglycation properties of the extracts. Results: All the investigated extracts were found to contain high level of total phenols as well as potent antioxidant activities. Kernel extracts showed the highest total phenol contents and DPPH radical scavenging activities whereas higher oxygen radical absorbance capacity values were observed for leave, root and bark extracts. Besides, extracts from leaves, roots and barks from both cultivars exhibited potent inhibitory effects against the formation of advanced glycation end products, with IC_(50) values lower than the standard positive control aminoguanidine. Conclusions: The potent antiglycation and antioxidative activities of these two Mangifera indica cultivars suggest a possible role in targeting aging, diabetic complications and oxidative stress related diseases. | Samba Fama Ndoye Didier Fraisse Blandine Akendengue Mbaye Diaw Dioum Rokhaya Sylla Gueye Cheikh Sall Insa Seck Catherine Felgines Matar Seck Francois Senejoux | 2018 | Asian Pacific Journal of Tropical Biomedicine2018，8，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员