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| 1 | Expression of calreticulin is associated with infiltration of T-cells in stage ⅢB colon cancer显示文摘AIM: To investigate the correlation between expression of calreticulin and infiltration of lymphocytes in stage ⅢB colon cancer. METHODS: Sixty-eight pathologically-confirmed speci-mens were obtained from stage ⅢB (T3N1M0) colon cancer patients who underwent radical resection between January 1999 and May 2002 at the Cancer Center of Sun Yat-Sen University, Guangzhou, China. Immuno-histochemical analysis was performed to show infiltration of lymphocytes and expression of calreticulin in colon cancer. Association between calreticulin expression, infiltration of lymphocytes, and 5-year survival rate of patients was assessed. RESULTS: The expression level of calreticulin was lower in cancer nest than in its adjacent normal epithelium since 61.8% (42/68) of the samples were stained with calreticulin in colon cancer. The expression of calreticulin in colon cancer was associated with the infi ltration of CD45RO+ cells rather than with that of CD3+ cells. In addition, the stronger expression of calreticulin and the higher infiltration of CD3+ and CD45RO+ cells in colon cancer were associated with the higher 5-year survival rate of patients. CONCLUSION: Expression of calreticulin is associated with infiltration of T-cells, which implies that a low expression level of molecular marker may represent a new mechanism underlying immune escape in colon cancer. | Rui-Qing Peng, Ya Ding, Xing Zhang, Yi-Xin Zeng, Xiao- Shi Zhang, State Key Laboratory of Oncology in South China, Biotherapy Center, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Ying-Bo Chen, Zhi-Wei Zhou, State Key Laboratory of Oncology in South China, Department of Gastric and Pancreatic Oncology, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Rong Zhang, State Key Laboratory of Oncology in South China, Department of Endoscopy, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China Xing-Juan Yu, Yi-Xin Zeng, State Key Laboratory of Oncology in South China, Department of Experimental Research, Cancer Center, Sun Yat-Sen University, 651 Dongfeng R E, Guangzhou 510060, Guangdong Province, China | 2010 | World Journal of Gastroenterology2010，16，19： | 16 |
| 2 | Boundary Layer Theory and the Zero-Viscosity Limit of the Navier-Stokes Equation | Weinan E Department of Mathematics and Program in Applied and Computational Mathematics,Princeton University,USA | 2000 | Acta Mathematica Sinica,English Series2000，16，2： | 10 |
| 3 | Eco-environment evolvement analysis of Ertan reservoir catchment based on remote sensing显示文摘Hydropower project may bring with it social-economic profits as well as side effects.The built dam and reservoir often cause some problems to the surrounding areas,among which the ecological and environmental effects caused by hydropower projects are always concerned by the public.In this article,we take the Ertan reservoir catchment as the research area and try to quantitatively analyze the variation of vegetation cover and soil erosion by remote sensing technique,and to comprehensively assess the evolvement and development trend of reservoir catchment.Soil erosion,land use/cover are used as ecological and environmental indicators which reflect the changes before,after and in the period of the construction of Ertan hydropower station.Supported by the multi-source remote sensing data(from satellite Landsat and CBERS) and DEM data,the land use/cover is interpreted through RS images which are classified both by unsupervised and supervised method,and the driving factors of the ecological changes are also analyzed.At the same time,the changes of soil loss are also monitored and analyzed during flood seasons of Ertan reservoir area before and after reservoir impoundment(1995,2000 and 2005) using the revised universal soil loss equation(RUSLE) .The results show that during the recent 13 years the arable land area has decreased obviously,and construction area and water surface have increased slightly.The increase of vegetation cover has some relations with the implementation of local ecological projects,i.e.,de-farming to forestry and de-farming to pasture projects.At the same time,changes may also be caused by the climate adjustment in the reservoir area.In the ten years from 1995 to 2005,the high soil loss classes were transforming to lowly level classes continuously.All of these show that the soil loss of Ertan reservoir area is getting better. | PANG ZhiGuo ,GE DeXiang & FU Jun E State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin,,China Institute of Water Resources and Hydropower Research,Beijing 100048,China | 2011 | Science China(Technological Sciences)2011，54，S1： | 3 |
| 4 | MODELING OF SEDIMENT AND NONPOINT SOURCE POLLUTANT YIELD显示文摘For water and soil conservation and water pollution control, it is very important to simulate and predict the load of sediment and pollutant during storm-runoff. On the basis of analyzing the simultaneous measurements of flow, sediment and pollutants observed at watershed outlet, a practical sediment yield model is developed by standardizing the load rate. The results show that the standardized pollutant yield equals effective rainfall and the process of effective load yield is the same as effective rainfall hyetograph. Comparison with measured data show that this model is applicable to various pollutants. | Huai’en LI, Xiaokang Hong and Bing SHEN Professor, Institute of Environmental Sciences, Xi’an University of Technology, Xi’an 710048, Shaanxi Province, P.R.China. Ph.D. studdent in Hydrology and Water Resources, Xi’an University of Techology, and Senior E | 2001 | International Journal of Sediment Research2001，16，3： | 2 |
| 5 | Causes cortical brain slices during hypoxia and ischemic: role of ion channels and membrane damage显示文摘 | PHILIP E BICKER M BONN of calcium accumulation in rat C M | 1994 | Brain Res1994，665，2： | 1 |
| 6 | Comparison of Two Spectrofluorimetric Methods Applied to Water Samples 显示文摘 | Eiroa A A Blanco E V Machia P L Resolution of Benzo(a)pyrene in Complex Mixtures of Other Polycyclic Aromatic Hydrocarbons | 2000 | Analyst2000，125，7： | 1 |
| 7 | Posterior reversibleencephalopathy syndrome (PRES):Features on CT and MRimaging显示文摘 | Hugonnet E Da Ines D Boby H | 2012 | Diagn Interv Imaging2012，94，1： | 1 |
| 8 | Comparison of fixed and rotating spray plate sprinklers显示文摘 | Faci J M Salvador R Play in E | 2001 | Journal of Irrigation and Drainage Engineering2001，127，4： | 1 |
| 9 | Polyphenol contents and in vitro antioxidant ac- tivities of lyophilised aqueous extract of kiwifruit (Actinidia deli- ciosa)显示文摘 | Bursal E G L In I | 2011 | Food Research International2011，44，5： | 1 |
| 10 | Regulation of RPE intercellular junction integrity and function by hepatocyte growth factor显示文摘 | Barron E He S | 2002 | Invest Ophthalmol Vis Sci2002，43，： | 1 |
| 11 | Selective blockage of in-termediate-Conductance Ca2+-Activated K+Channel sup-presses proliferation of microvascular and macrovascular en-dothelial cells and angiogenesis in vitro显示文摘 | Ivica G Ines E Philipp H | 2005 | ArteriosclerosisThromb Vasc Biol2005，25，： | 1 |
| 12 | Shear stress-induced up-regulation of the intermediate-conductance Ca2+-activated K+ channel in human endothelium显示文摘 | Susanne B Anne K Ines E | 2003 | Cardiovasc Res2003，60，： | 1 |
| 13 | Yong, Regean-Era Efficiency Program Called Wastefull显示文摘 | Senator Jim Sasser as Quoted in John E | 1990 | Washington Post1990，，： | 1 |
| 14 | Helicobacter pylori infection is identified as a cardiovascular risk factor in Central Mricans显示文摘 | Longo - Mbenza B Nsenga IN Mokondjimobe E | 2012 | Vase Health Risk Manag2012，6，： | 1 |
| 15 | Nonlocal boundary value problem of the _rst kind for a Sturm-Liouville operator in its differential and finite difference aspects显示文摘 | Il’IN V A MOISEEV E I | 1987 | Differential Equations1987，23，7： | 1 |
| 16 | using elicitation and precursor 显示文摘 | Shinde A N Malpathak N Fulzele D E Optimized production of isoflavones in cell cultures of Psoralea corylifolia L | 2009 | Feeding BiotechnolBioproc Eng2009，14，： | 1 |
| 17 | Performance of rotating spray plate sprinklers in indoor experiments显示文摘 | Sourell H Faci J M Play in E | 2003 | Journal of Irrigation and Drainage Engineering2003，129，5： | 1 |
| 18 | Correlation of the Tei index with invasive measurement of ventricular function in a porcine mode 显示文摘 | La Corte J C Cabreriza S E Rabk in D G | 2003 | Am soe Echocardiogr2003，16，5： | 1 |
| 19 | Activation-induced cell death vs passive macrophage-dependent deletion 显示文摘 | Gonzalo JA Baixeras E Gonzalez-Garcia A Differential in vivo effects of a superantigen and an antibody targeted to the same T cell receptor | 1994 | J Immunol1994，152，： | 1 |
| 20 | 3MoO3显示文摘 | MACHADO-CHARRY E ORDEJON P CANADELL E Analysis of scanning tunneling microscopy images of the charge-density-wave phase in quasi-one-dimensional Rb 0 | 2006 | Phys Rev B2006，74，15： | 1 |
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