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    题名 作者 年代 出处 被引量
1Lamivudine resistance mutations in patients infected with hepatitis B virus genotype D显示文摘AIM: To determine the distribution of viral genotypes for primary or acquired lamivudine resistance. METHODS: A total of 283 patients with chronic hepatitis B virus (HBV) infection (245 patients with chronic hepatitis B and 38 inactive hepatitis B surface antigen carriers) were included in the study. The HBV geno-type was determined by using quantitative real-time polymerase chain reaction and sequence analysis, and tyrosine-methionine-aspartate-aspartate (YMDD) motif mutations were determined using the reverse transcriptase hybridization method. RESULTS: Lamivudine resistance was determined in a total of 25 (10.7%) chronic hepatitis B patients. Eight subjects (4%) had primary resistance to lamivudine, and 17 (53.1%) had secondary resistance to lamivudine. Genotype D, which was isolated from 267 of the patients with chronic HBV infection, was the dominant genotype in Turkey. CONCLUSION: Identification of YMDD motif mutations should have a positive impact on the selection of proper antiviral medication for patients, even for those who are nucleoside nave.Orhan Yιldιz Bilgehan Aygen Nese Demirtürk Tuna Demirdal Dilara Inan Taner Yιldιrmak Arzu Kantürk Ediz Tütüncü Hepatitis B Study Group 2011World Journal of Gastroenterology2011,17,45:3
2Importance of catalase in the adaptive re- sponse to hydrogen peroxide:Analysis of acatalasaemic Saccharomyces cerevisiae显示文摘Izawa S inane Y Kimura A 1996Biochemical Journal1996,320,:1
3Antioxidant effect of mint, laurel and myrtle leaves essential oils on pomegranate kernel, poppy, grape and linseed oils 显示文摘inan O Ozcan M M A1 Juhaimi F Y 2012J Clean Prod2012,27,:1
4Schedule-dependent cytotoxicity of 5-fluorouracil and ifinotecan in p53 mutant human colon cancer显示文摘Janaka K Inane Y Hiro J 2007J Exp Clin Cancer Res2007,26,2:1
5Over- and under-ex- pressed microRNAs in human colorectal cancer 显示文摘Motoyama K Inane H Takatsuno Y 2009Int J Oncol2009,34,4:1
6Giant congenital epiglottic cystpresenting with airway obstruction at birth 显示文摘Kislal FM Acar B Inan Y 2012J Craniofac Surg2012,23,2:1
7Tumor thrombectomy without bypass for low - grade malignant tumors extending into the inferior vena cava: report of two cases显示文摘Jibiki M Inane Y Sugano N 2006Surg Today2006,36,5:1
8Low Dielectric and Thermal Stable Polyimides with Fluorene Structure 显示文摘Goto K Kakuta M Inane Y 2000Journal of Photopolymer Science & Technology2000,13,2:1
9Thyroid-stimulating antibody is related to Graves'ophthalmopathy but thyrotropin-binding inhibitor immunogIobulin is related to hyperthyroidism in patients with Graves'disease 显示文摘Noh JY Hamada N Inane Y 2000Thyroid2000,10,4:1
10Heating, ionization and upward discharges in the mesosphere due to intense quasi-electrostatic thundercloud fields显示文摘Pasko V P Inan U S Taranenko Y N 1995Geophysical Research Letters1995,22,:1
11Halogenated and phosphorous containing difunctional monomers for UV curable application显示文摘Inan T Y Emel Yildiz Ekrem Ekinci 1999Polymer Preprints1999,40,1:1
12Fractional anisotropy value bydiffusion tensor magnetic resonance imaging as a predictor of celldensity and proliferation activity of glioblastomas显示文摘Beppu T Inane T Shibata Y 2005Surg Neuroi2005,63,1:1
13Well- defined block copolymer ionomers and their blend membranes for proton exchange membrane fuel cell 显示文摘Erdogan T Unveren E E Inan T Y 2009J Membr Sci2009,344,12:1
14Clinical evaluation of forty-four patients with necrotizing fasciitis显示文摘Turhan O Büyüktuna SA Inan D 0,,01:1
15Rapidly solidified power metallurgy Mg97Znl Y2 alloys with excellent tensile yield strength above 600 MPa显示文摘Kawamura Y Hayashi K Inane A 2001Materials Transitions2001,42,7:1
16Prediction of prognosis of estrogenregulated genes显示文摘Yoshida N Omoto Y Inane A 2004Cancer Sci2004,95,6:1
17Maitake beta - glucan en- hances therapeutic effect and reduces myelosupression and nephro- toxicity of cisplatin in mice显示文摘Masuda Y Inane M Miyata A 2009Int Immunopharmacol2009,9,5:1
18Prognostic significance of monocarboxylate transporter 4 expression in patients with colorectal cancer显示文摘Nakayama Y Tofigoe T Inane Y 2012Exp Ther Med2012,3,1:1
19Oral administration of soluble beta - glucans extracted from Grifola frondosa induces systemic anti- tumor immune response and decreases in tumor - bearing mice显示文摘Masuda Y Inane H Ohta H 2013Int J Cancer2013,133,1:1
20Gefitinib enhances the effi- cacy of photodynamic therapy using 5-aminolevulinic acid in ma- lignant brain tumor cells 显示文摘Sun W Kajimoto Y Inane H 2013Photodiagnosis Photodyn Ther2013,10,1:1
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