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| 1 | PD-L1在滋养细胞肿瘤中高表达可用于鉴别诊断显示文摘PD-1/PD-L是调控免疫反应和自身免疫耐受机制的关键点。PD-1属于免疫球蛋白超家族成员的细胞表面受体,主要表达于活化的T细胞;PD-L1是PD-1的配体,一旦与受体结合可抑制与T细胞活化相关的蛋白激酶。研究证实PD-L1高表达可促进肿瘤细胞免疫逃逸,且与肿瘤侵袭性及预后差相关。近年来,针对PD-1/PD-L的免疫抑制剂应用于肿瘤治疗取得一定的疗效,而PD-L1免疫组化染色是判断新型免疫抑制剂治疗反应的有效方法。Inaguma等采用免疫组化分析5536例各种类型肿瘤(包括生殖细胞、上皮细胞、间皮细胞、黑色素细胞/神经外胚层及淋巴造血系统肿瘤)以及人正常组织(包括胚胎组织)中PD-L1的表达。 | Inaguma S Wang Z Lasota J 杨海玉 刘勇 | 2016 | 临床与实验病理学杂志2016，32，11： | 9 |
| 2 | Candidate compounds with perovskite structure for high lithium ionic-conductivity显示文摘 | Inaguma Y Chen L Itoh M | 1994 | Solid State Ionics1994，70，： | 1 |
| 3 | The effect of the hydrostatic pressure on the ionic cnductivity in a perovskite lanthanum lithium titanate显示文摘 | INAGUMA Y YU J SHAN Y J | 1995 | J Electrochem Soc1995，142，1： | 1 |
| 4 | Plasmablastic lymphoma of the stomach in an HIV-negative patient 显示文摘 | Hashimoto M Inaguma S Kasai K | 2012 | Pafllol Int2012，62，11： | 1 |
| 5 | Brain-derived neurotrophic factor,nerve growth and neurotrophin-3 selected regions of the rat brain following kainic acid-induced seizure activity显示文摘 | Katoh-Semba R Takeuchi IK Inaguma Y | 1999 | Neurosci Res1999，11，： | 1 |
| 6 | Nephrologist care for months or more increases hemodialysis initiation with per- manent vascular access 显示文摘 | Inaguma D Ando R Ikeda M | 2011 | Clin Exp Nephrol2011，15，5： | 1 |
| 7 | GLI1 facilitates the migration and invasion of pancreatic cancer cell through MUC5AC-mediated attenuation of E-cadherin显示文摘 | Inaguma S Kasai K Ikeda H | 2011 | 30(6):714 -7232011，30，6： | 1 |
| 8 | High ionic conductivity in lithium lanthanum titanate显示文摘 | Inaguma Y Chen L Itoh M | 1993 | Solid State Commun1993，86，： | 1 |
| 9 | Dielectric Properties of A-site Deficient Perovskite-type Lanthanum-calcium-titanium Oxide Solid Solution System显示文摘 | I.S.Kim W H Jung Y Inaguma | | 0，，03： | 1 |
| 10 | High Ionic Conductivity in Lithium Lanthanum Titanate显示文摘 | Inaguma Y Liquan C Itoh | 1993 | Solid State Commun1993，86，： | 1 |
| 11 | Is the volume of the parathyroid gland a predictor of Maxacalcitol response in advanced secondary hyperparathyroidism?显示文摘 | Tominaga Y Inaguma D Matsuoka S | 2006 | Ther Apher Dial2006，10，2： | 1 |
| 12 | Relationship between seruml, 25 - dihydroxy vitamin D and mortality in patients with pre- dialysis chronic kidney disease 显示文摘 | Inaguma D Nagaya H Hara K | 2008 | Clin Exp Nephrol2008，12，： | 1 |
| 13 | $CL/TAL1 interrupting locus derepresses GLI1 from the negative control of suppressor-of-fused in pancreatic cancer cell显示文摘 | Kasai K Inaguma S Yoneyama A | 2008 | Cancer Res2008，68，19： | 1 |
| 14 | Fabrication of Cu-based functionally graded materials dispersing fine SIC particles by a centrifugal mixed-powder method 显示文摘 | Sato Hisashi Inaguma Yoshifumi Watanabe Yoshimi | 2010 | Materials Science Forum2010，，： | 1 |
| 15 | Valency pair and properties of 1, 1 ordered perovskite-type compounds Sr2 MMoO6 ( M= Mn, Fe,Co) 显示文摘 | Itoh M Ohta I Inaguma Y | 1996 | Mater Sci Eng B1996，41，： | 1 |
| 16 | Brain derived neuro trophic factor,nerve growth and neuro trophin3 selected regions of the rat brain following kainic acid2 induced seizure activity显示文摘 | KatohSemba R Takeuchi IK Inaguma Y | 1999 | Neurosci Res1999，35，1： | 1 |
| 17 | Molecular Dynamics Simulation in SrTiO3显示文摘 | Yoshiyuki Inaguma and Mitsuru Itoh | 1998 | Solid State Ionics1998，108，： | 1 |
| 18 | Successful pregnancy in a patient with chronic myeloid leukemia under treatment with ima- tinib 显示文摘 | Tsuzuki M Inaguma Y Handa K | 2009 | Intern Med2009，48，16： | 1 |
| 19 | GLI1 facilitates the migration and invasion of pancreatic cancer cells through MUC5AC-mediated attenuation of E-cadherin显示文摘 | Inaguma S Kasai K Ikeda H | | 0，，06： | 1 |
| 20 | 显示文摘 | Inaguma Y Chen Liquan Mitsuru Itoh | 1993 | Solid State Commun1993，86，： | 1 |
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