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1人工全膝关节中多孔钽金属型和骨水泥型胫骨假体周围骨矿物质密度比较显示文摘背景:多孔钽金属近年来用作全膝关节置换的金属植入材料。其多孔性、低弹性模量和高摩擦性能可保证良好的生理负荷传导并保留假体周围的骨储备。但就我们所知,这种小梁金属(TrabecularMetal)胫骨假体对周围骨矿物质密度的影响未见文献报道。本文的目的是对使用非骨水泥的小梁金属胫骨假体和骨水泥型胫骨假体关节周围骨矿物质密度进行比较。方法:对使用小梁金属胫骨假体和使用骨水泥固定的钴铬钼合金胫骨假体各28个膝分别在术前2周、术后2周、术后6、12、18和24个月进行双能x线吸收光谱扫描,以评价假体周围骨矿物质密度。所有手术均由一名医师操作并采用髌旁内侧入路。结果:术前两组股骨颈、腕关节、腰椎椎体或膝关节的骨密度均无明显差异。术后两组的胫骨骨密度均下降。但术后24个月的胫骨侧位x线片显示小梁金属胫骨假体周围的骨密度减低明显小于骨水泥型胫骨假体组(平均值±标准差,-6.7%±22.9%与-36.8%+24.2%;p=0.002)。两组患者的膝关节学会(Knee Society)评分、膝关节活动度和腰椎椎体骨密度在术后24个月无明显差异。假体微动和假体周围骨折在两组膝关节中均未见到。结论:全膝关节置换术使用小梁金属胫骨假体的胫骨外侧平台的骨密度降低小于使用骨水泥型胫骨假体的膝关节。确定多孔钽金属胫骨假体用于全膝关节置换的长期临床疗效尚待进一步研究。Yukihide Minoda Akio Kobayashi Hiroyoshi Iwaki Mitsuhiko Ikebuchi Fumiaki Inori Kunio Takaoka 赵建宁(译) 包倪荣(译) 2010中华骨科杂志2010,30,6:4
2Insulin resistance rather than hyperinsulinemia more closely associated with essential hypertension显示文摘Yokota C Ikebuchi M Suzuki M 1995Clin Exp Hypertens1995,17,:1
3The interosseous and lumbrieal muscles in the human hand, with spe- cial reference to the insertions of the interosseous muscles显示文摘Ikebuchi Y Murakami T Ohtsuka A 1988Acta Med Okayama1988,42,:1
4Different adhesive characteristics and VLA-4 expression of CD34 (+) progenitors in G0/G1 versus S + G2/M phases of the cell cycle 显示文摘 Ikebuchi K Hirayama F 1998Blood1998,92,3:1
5Virus inactivation in superoxide dismutase preparations by ultraviolet light irradiation显示文摘Hirayama J Abe H Ikebuchi K 1998Biol Pharm Bull1998,21,6:1
6Interleukin 6 enhance- ment of interleukin 3-dependent proliferation of multipotential he- mopoietic progenitors显示文摘Ikebuchi K Wong GG Clark SC 1987Proc Natl Acad Sci U S A1987,84,24:1
7Granulocyte colony-stimulating factor enhances interleukin 3-dependent proliferation of multipotential hemopoietic progenitors显示文摘Ikebuchi K Clark SC Ihle IN 1988Proc Natl Acad Sci USA1988,85,10:1
8Pulmonary embolism in patients with isolated soleal vein thrombosis 显示文摘Ohgi S Tachibana M Ikebuchi M 1998Angiology1998,49,9:1
9Superoxide anion increases intracellular pH,intracellular free calcium and arachidonate release in human amnion cell显示文摘Ikebuchi Y Masumoto K Tasaka K 0,,20:1
10Porous tantalum tibial component prevents periprosthetic loss of bone mineral density after total knee arthroplasty for five years:a matched cohort study显示文摘Minoda Y Kobayashi A Ikebuchi M 2013J Arthroplasty2013,28,10:1
11Effects of filtration and gamma radiation on the accumulation of RATNES and transforming growth factor-β1 in apheresis platelet concentrates during storage 显示文摘Fujihara M Ikebuchi K Wakamoto S 1999Transfusion1999,39,5:1
12Thin-layer chromatography with flame ionitation detection for the determination of tetrodotoxin in biological fluids显示文摘Ikebuchi J Suenaga K Kotoku S 1988Chronmlogr1988,432,:1
13Increase of cells expressing PD-L1 in bovine leukemia virus infection and enhancement of anti-viral immune responses in vitro via PD-L1 blockade显示文摘Ikebuchi R Konnai S Shirai T 2011Vet Res2011,42,1:1
14Abnomal glutathione metabolism and increased cytotoxicity caused by H202 in human umbilical vein endothelial cells cultured in high glucose medium显示文摘Kashiwagi A Asahina T Ikebuchi M 1994Diabetologia1994,37,:1
15A stochastic approach to short-term rainfall prediction using a physically based conceptual rainfall mode 显示文摘Sugimoto S Nakakita E Ikebuchi S 2001Journal of Hydrology2001,242,:1
16Demonstration of insulin resistance in coronary artery disease documented with angiography 显示文摘 Suzuki M Ikebuchi M 1996Diabetes Care1996,19,:1
17RANKL subcellular trafficking and regulatory mechanisms in osteocytes显示文摘Honma M Ikebuchi Y Kariya Y 2013Journal of Bone and Mineral Research2013,28,9:1
18Mechanism and clinical implication of insulin resistance syndrome显示文摘Suzuki M Ikebuchi M Shinozaki K 1996Diabetes1996,45,3:1
19Increase of cells expressingPD-L1 in bovine leukemia virus infection and enhancement ofanti-viral immune responses in vitro via PD-L1 blockade 显示文摘Ikebuchi R Konnai S Shirai T 2011VetRes2011,42,1:1
20Comparison of sensitivity to ultraviolet B irradiation between human lymphocytes and hematopoietic stem cells显示文摘Azuma H Ikebuchi K Yamaguchi M 2000Blood2000,96,:1
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